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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 9054 productos de "Metabolismo"

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  • RXPA 380

    CAS:
    RXPA 380: C-terminal ACE inhibitor, Ki=3nM; IC50=2.5nM for C-domain ACE mutants.
    Fórmula:C33H36N3O7P
    Forma y color:Solid
    Peso molecular:617.63
  • 9-SAHSA

    CAS:
    Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids that are modulated by dietary changes such as fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds generally consist of a fatty acid chain of either 16 or 18 carbons (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified to a similarly long hydroxy fatty acid. One specific FAHFA, 9-SAHSA, features stearic acid esterified at the 9th carbon of hydroxy stearic acid. The concentration of 9-SAHSA is notably increased in the serum of glucose-tolerant AG4OX mice, which specifically express the Glut4 glucose-transporting protein in adipose tissue.
    Fórmula:C36H70O4
    Forma y color:Solid
    Peso molecular:566.9
  • CAY10632

    CAS:
    Very long chain polyunsaturated fatty acids (VLCPUFA), notably present in the retina, sperm, and brain, have yet to be fully understood in terms of their biosynthesis and functional roles within these tissues. Recent research, particularly with the elongation of very long-chain FA-4 protein, indicates a distinct function for VLCPUFAs in retinal development and the progression of macular degeneration. CAY10632, a specific C32:6 VLCPUFA, while largely unexplored in its biological activities, is believed to play a role in maintaining normal function of photoreceptor cells in the retina.
    Fórmula:C32H52O2
    Forma y color:Solid
    Peso molecular:468.766
  • VU0155069 hydrochloride

    CAS:
    VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent and selective inhibitor of phospholipase D (PLD), exhibiting IC50 values of 46 nM for PLD1 and 933 nM for PLD2. It effectively inhibits the migration of both human and mouse breast cancer cell lines [1] [2].
    Fórmula:C26H28Cl2N4O2
    Forma y color:Solid
    Peso molecular:499.43
  • Dinophysistoxin 1

    CAS:
    Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid), a causative agent of diarrhetic shellfish poisoning, exhibits tumor-promoting activity and also acts as a skin
    Fórmula:C45H70O13
    Forma y color:Solid
    Peso molecular:819.03
  • Kelatorphan

    CAS:
    Kelatorphan is an enkephalin degrading enzyme full inhibitor.
    Fórmula:C14H18N2O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:294.3
  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium

    CAS:
    1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), a lysophospholipid with oleic acid (18:1) at the sn-1 position, finds application in creating micelles, liposomes, and various artificial membranes, notably in lipid-based drug delivery systems.
    Fórmula:C24H46NaO9P
    Forma y color:Solid
    Peso molecular:532.587
  • ICMT-IN-33

    CAS:
    ICMT-IN-33 (compound 73) functions as an ICMT inhibitor with an IC50 value of 0.46 μM [1].
    Fórmula:C20H24ClNO
    Forma y color:Solid
    Peso molecular:329.86
  • H2-003

    CAS:
    H2-003 is a selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2).
    Fórmula:C25H26N4O4
    Forma y color:Solid
    Peso molecular:446.5
  • FXIa-IN-7

    CAS:
    FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.
    Fórmula:C28H28N2O4
    Pureza:98.55%
    Forma y color:Solid
    Peso molecular:456.53
  • Selenocystine

    CAS:
    <p>Selenocystine, a broad-spectrum anticancer agent, effectively induces DNA damage, notably DNA double-strand breaks (DSBs), in HepG2 cells, showcasing</p>
    Fórmula:C6H12N2O4Se2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:334.09
  • C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0)

    CAS:
    C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is a lipid molecule that can be used in life science related research. The CAS number of C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is 34249-41-7.
    Fórmula:C36H71NO4
    Forma y color:Solid
    Peso molecular:581.967
  • l-Primaquine

    CAS:
    l-Primaquine is used to treat and prevent malaria and to treat Pneumocystis pneumonia.
    Fórmula:C15H21N3O
    Forma y color:Solid
    Peso molecular:259.35
  • G43-C3-TEG

    CAS:
    G43-C3-TEG is a glycosyl-transferase inhibitor that diminishes biofilm formation by inhibiting the synthesis of extracellular polysaccharides (EPS) [1].
    Fórmula:C24H27N3O9S
    Forma y color:Solid
    Peso molecular:533.55
  • 13-OAHSA

    CAS:
    <p>13-OAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), results from the esterification of oleic acid to 13-hydroxy stearic acid. It represents a significant component of the FAHFA family, most abundantly expressed in the serum of glucose-tolerant AG4OX mice that exhibit adipose tissue-specific overexpression of the Glut4 glucose transporter. Similar to other FAHFAs which are known to enhance glucose tolerance, stimulate insulin secretion, and exert anti-inflammatory effects, 13-OAHSA may play a pivotal role in managing metabolic syndrome and inflammation.</p>
    Fórmula:C36H68O4
    Forma y color:Solid
    Peso molecular:564.9
  • ICMT-IN-30

    CAS:
    ICMT-IN-30 (compound 67) is an ICMT inhibitor with an IC50 value of 0.27 μM [1].
    Fórmula:C19H25NOS
    Forma y color:Solid
    Peso molecular:315.47
  • Tetramyristoylcardiolipin

    CAS:
    Tetramyristoylcardiolipin (TMCL), an anionic lipid, plays a crucial role in studying cell membrane function and drug delivery mechanisms [1].
    Fórmula:C65H132N2O17P2
    Forma y color:Solid
    Peso molecular:1275.69
  • Tetrahydro-11-dehydrocorticosterone

    CAS:
    Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].
    Fórmula:C21H32O4
    Forma y color:Solid
    Peso molecular:348.48
  • ICMT-IN-34

    CAS:
    ICMT-IN-34 (compound 39) serves as an effective inhibitor of ICMT, exhibiting an IC50 value of 0.17 μM [1].
    Fórmula:C21H25Cl2NO
    Forma y color:Solid
    Peso molecular:378.34
  • (±)-HIP-A

    CAS:
    <p>(±)-HIP-A is an excitatory amino acid transporter blocker.</p>
    Fórmula:C6H8N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:172.14