Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(42 productos)
- Aminopeptidasa(76 productos)
- CETP(20 productos)
- Anhídrido carbónico(196 productos)
- Caseína quinasa(139 productos)
- DHFR(30 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(302 productos)
- FAAH(64 productos)
- FXR(62 productos)
- Factor Xa(87 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(227 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(34 productos)
- Hidroxilasa(36 productos)
- IDO(84 productos)
- LDL(7 productos)
- Lipasa(107 productos)
- Lípido(62 productos)
- Lipoxigenasa(133 productos)
- MAO(85 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(170 productos)
- PED(1 productos)
- PKM(17 productos)
- PPAR(170 productos)
- Fosfolipasa(85 productos)
- ROR(47 productos)
- Receptor de retinoides(20 productos)
- SGK(10 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(43 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9197 productos de "Metabolismo"
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Lp-PLA2-IN-10
Lp-PLA2-IN-10, a potent Lp-PLA2 inhibitor, may research neurodegenerative and cardiovascular diseases.Fórmula:C21H15F5N4O4Forma y color:SolidPeso molecular:482.36Z57346765
CAS:Z57346765 is a specific PGK1 inhibitor that inhibits PGK1-dependent cell proliferation by decreasing the metabolic enzyme activity of PGK1 during glycolysis.Fórmula:C17H18N4OPureza:99.85%Forma y color:SolidPeso molecular:294.35DGAT2-IN-3
CAS:DGAT2-IN-3 (compound 9) is an inhibitor of DGAT2 with an IC50 value of 0.4 nM. It is utilized in research related to fatty liver disease, diabetes, and cardiovascular diseases.Fórmula:C21H20F4N4O5SForma y color:SolidPeso molecular:516.47Glucokinase activator 7
CAS:Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].Fórmula:C14H13N3O2SForma y color:SolidPeso molecular:287.337BMS-214662 mesylate
CAS:BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.Fórmula:C26H27N5O5S3Forma y color:SolidPeso molecular:585.718RORγt modulator 5
CAS:RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.Fórmula:C27H22F5N3O6SForma y color:SolidPeso molecular:611.54Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Fórmula:C24H20ClN3O3SForma y color:SolidPeso molecular:465.95Cilazaprilat
CAS:Cilazaprilat is the active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.Fórmula:C20H27N3O5Forma y color:SolidPeso molecular:389.45ABD957
CAS:ABD957: covalent ABHD17 depalmitoylases inhibitor, IC50 0.21µM for ABHD17B, blocks N-Ras, halts NRAS-mutant AML cell growth.Fórmula:C27H36F3N7O5SForma y color:SolidPeso molecular:627.68NAZ2329
CAS:NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) & hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.Fórmula:C21H18F3NO4S3Forma y color:SoildPeso molecular:501.56CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Fórmula:C27H28N2O6SForma y color:SolidPeso molecular:508.59TMX-4116
CAS:TMX-4116 is a CK1α degrader targeting multiple cell lines with DC50s below 200 nM, used in multiple myeloma research and protein degradation strategy studies.Fórmula:C17H19N5O4SForma y color:SolidPeso molecular:389.43Enpp-1-IN-11
Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.Fórmula:C15H15N5O3SForma y color:SolidPeso molecular:345.38Darlifarnib
CAS:Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.Fórmula:C29H20N6OForma y color:SolidPeso molecular:468.509Gcase activator 2
CAS:Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.Fórmula:C21H24N4O2Pureza:99.51% - 99.76%Forma y color:SolidPeso molecular:364.44PKM2-IN-9
CAS:PKM2-IN-9 (compound C1) is a potent inhibitor of PKM2, demonstrating a 75% inhibition rate at 50 μM. It plays a significant role in cancer research.Fórmula:C24H22N4O2Forma y color:SolidPeso molecular:398.457QGC583
CAS:QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.Fórmula:C13H20NO5PForma y color:SolidPeso molecular:301.28PDE4-IN-12
PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).Fórmula:C34H35NO6Forma y color:SolidPeso molecular:553.64S-15176
CAS:S-15176 is an inhibitor of the mitochondrial permeability transition pore (PTP). It effectively suppresses mitochondrial swelling induced by tert-butyl hydroperoxide, with an IC50 value of 45.7 μM. S-15176 prevents the opening of PTP, thus averting the dissipation of mitochondrial membrane potential and the oxidation of NAD(P)H, while enhancing mitochondrial calcium loading capacity. It holds potential for research into ischemia-reperfusion injury.
Fórmula:C31H48N2O4SForma y color:SolidPeso molecular:544.79L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Fórmula:C36H35ClN6OSPureza:98%Forma y color:SolidPeso molecular:635.22
