Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(42 productos)
- Aminopeptidasa(76 productos)
- CETP(20 productos)
- Anhídrido carbónico(196 productos)
- Caseína quinasa(138 productos)
- DHFR(30 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(300 productos)
- FAAH(64 productos)
- FXR(62 productos)
- Factor Xa(86 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(226 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(34 productos)
- Hidroxilasa(36 productos)
- IDO(84 productos)
- LDL(7 productos)
- Lipasa(107 productos)
- Lípido(62 productos)
- Lipoxigenasa(133 productos)
- MAO(86 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(169 productos)
- PED(1 productos)
- PKM(17 productos)
- PPAR(170 productos)
- Fosfolipasa(85 productos)
- ROR(47 productos)
- Receptor de retinoides(20 productos)
- SGK(10 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(44 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9202 productos de "Metabolismo"
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OSI-413 free base
CAS:OSI-413 (free base) (CP 373413) is the primary metabolite of Erlotinib. Erlotinib (CP-358774) acts as a direct EGFR tyrosine kinase inhibitor with an IC50 of 2 nM against human EGFR.Fórmula:C21H21N3O4Forma y color:SolidPeso molecular:379.409Porphobilinogen
CAS:Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.Fórmula:C10H14N2O4Pureza:98%Forma y color:SolidPeso molecular:226.23(R,R)-BMS-986397
CAS:(R,R)-BMS-986397 is a CK1α degrader with a DC50 ranging from 0.1 to 0.5 pM. This compound is applicable in leukemia research.Fórmula:C21H16ClF3N4O4Forma y color:SolidPeso molecular:480.82PKM2-IN-9
CAS:PKM2-IN-9 (compound C1) is a potent inhibitor of PKM2, demonstrating a 75% inhibition rate at 50 μM. It plays a significant role in cancer research.Fórmula:C24H22N4O2Forma y color:SolidPeso molecular:398.457Enpp-1-IN-11
Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.Fórmula:C15H15N5O3SForma y color:SolidPeso molecular:345.38TMX-4116
CAS:TMX-4116 is a CK1α degrader targeting multiple cell lines with DC50s below 200 nM, used in multiple myeloma research and protein degradation strategy studies.Fórmula:C17H19N5O4SForma y color:SolidPeso molecular:389.43BAY R3401
CAS:BAY R3401 is an orally active inhibitor of glycogen phosphorylase, leading to irreversible and non-selective inhibition of liver glycogenolysis. It suppresses glycogen breakdown in hepatocytes with IC50 values of 27.06 μM in HL-7702 cells and 52.83 μM in HepG2 cells. BAY R3401 is applicable for research in type 2 diabetes.Fórmula:C20H22ClNO4Forma y color:SolidPeso molecular:375.846L 671776
CAS:L 671776 is an inositol monophosphatase inhibitor.Fórmula:C23H32O5Pureza:98%Forma y color:SolidPeso molecular:388.5LXRα agonist 1
CAS:LXRα agonist 1 (Compound 40) is a selective activator of LXRα, with an EC50 of 42 nM, and also demonstrates some activation effects on LXRβ, with an EC50 of 266 nM. It promotes target gene transcription by stabilizing the ligand-binding domain (LBD) of LXRα. When combined with the Raf inhibitor Sorafenib, LXRα agonist 1 shows significant antitumor activity in liver cancer cells. This compound is applicable in research focused on lipotoxicity-related cancers.Fórmula:C28H27N3O2Forma y color:SolidPeso molecular:437.533NAZ2329
CAS:NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) & hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.Fórmula:C21H18F3NO4S3Forma y color:SoildPeso molecular:501.56α-Amylase/α-Glucosidase-IN-7
CAS:α-Amylase/α-Glucosidase-IN-7 (Compound 3f) serves as a competitive inhibitor for the enzymes α-glucosidase and α-amylase, exhibiting IC50 values of 18.52 µM and 20.25 µM, respectively. Additionally, it effectively inhibits AChE and BChE, with IC50 values of 9.25 µM and 10.06 µM, respectively. This compound is useful in research related to diabetes and Alzheimer's [1].Fórmula:C15H9Cl2FN2OSForma y color:SolidPeso molecular:355.21Diacylglycerol acyltransferase inhibitor-1
CAS:Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.Fórmula:C21H23N5O2Pureza:98%Forma y color:SolidPeso molecular:377.44Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Fórmula:C24H20ClN3O3SForma y color:SolidPeso molecular:465.95ICMT-IN-55
CAS:ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].Fórmula:C22H26F3NO2Forma y color:SolidPeso molecular:393.44Antidiabetic agent 5
CAS:Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1].Fórmula:C17H15N3O4SForma y color:SolidPeso molecular:357.38RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Fórmula:C18H24N6O5SPureza:98%Forma y color:SolidPeso molecular:436.49T-3764518
CAS:T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Fórmula:C20H17F6N5O2Pureza:98%Forma y color:SolidPeso molecular:473.37Lp-PLA2-IN-10
Lp-PLA2-IN-10, a potent Lp-PLA2 inhibitor, may research neurodegenerative and cardiovascular diseases.Fórmula:C21H15F5N4O4Forma y color:SolidPeso molecular:482.36PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.Fórmula:C24H25N5O3Forma y color:SolidPeso molecular:431.49IDH1 Inhibitor 1
CAS:Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.Fórmula:C20H18F4N6O2Pureza:98%Forma y color:SolidPeso molecular:450.39
