HIF / HIF Prolilhidroxilasa
El Factor Inducible por Hipoxia (HIF) es un factor de transcripción que desempeña un papel crucial en las respuestas celulares a bajos niveles de oxígeno (hipoxia). La actividad del HIF está regulada estrictamente por las prolil-hidroxilasas de HIF, que dirigen al HIF para su degradación en condiciones normóxicas. Los inhibidores de la prolil-hidroxilasa de HIF pueden estabilizar el HIF, promoviendo la expresión de genes involucrados en la angiogénesis, la eritropoyesis y el metabolismo. Estos inhibidores son de gran interés en el tratamiento de afecciones como la anemia, las enfermedades isquémicas y el cáncer. En CymitQuimica, ofrecemos inhibidores de HIF/prolil-hidroxilasa HIF para apoyar su investigación en biología de la hipoxia, terapia del cáncer y regulación metabólica.
Se han encontrado 146 productos de "HIF / HIF Prolilhidroxilasa"
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Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFórmula:C6H13Li3O11Pureza:99.88%Forma y color:White Crystalline PowderPeso molecular:281.98Roxadustat
CAS:Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.Fórmula:C19H16N2O5Pureza:99% - 99.88%Forma y color:SolidPeso molecular:352.34Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Fórmula:C6H13NO5·HClPureza:99.77%Forma y color:White Solid CrystallinePeso molecular:215.63Hydroxycitric acid tripotassium hydrate
CAS:Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor effects.Fórmula:C6H7K3O8Pureza:99.85%Forma y color:White Solid CrystallinePeso molecular:324.41Tilorone dihydrochloride
CAS:Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
Fórmula:C25H36Cl2N2O3Pureza:98% - 99.86%Forma y color:Orange Yellow Crystal PowderPeso molecular:483.47Glucosamine
CAS:Glucosamine (Chitosamine) is used as a dietary supplement. Glucosamine has pharmacological effects on osteoarthritis cartilage. High-Quality, Low-Cost!
Fórmula:C6H13NO5Pureza:99.8% - 99.8%Forma y color:CoaPeso molecular:179.17Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Fórmula:C5H15N2O3PSPureza:99.59%Forma y color:White SolidPeso molecular:214.22Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Fórmula:C12H15N3O2SPureza:98.21% - 98.76%Forma y color:Colorless Crystals SolidPeso molecular:265.33(-)-Hydroxycitric acid lactone
CAS:(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, whichFórmula:C6H6O7Pureza:99.91%Forma y color:SolidPeso molecular:190.11EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Fórmula:C28H35NO3Pureza:98.36%Forma y color:SolidPeso molecular:433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.
Fórmula:C11H12Cl2N2O5Pureza:99.6% - 99.84%Forma y color:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidPeso molecular:323.13SYP-5
CAS:SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.Fórmula:C18H16O3SPureza:98.31%Forma y color:SolidPeso molecular:312.38Enarodustat
CAS:Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.Fórmula:C17H16N4O4Pureza:99.73% - 99.75%Forma y color:SolidPeso molecular:340.33Ref: TM-T15219
1mg37,00€2mg52,00€5mg74,00€10mg109,00€25mg178,00€50mg295,00€100mg439,00€1mL*10mM (DMSO)86,00€HIF-2α-IN-2
CAS:HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).Fórmula:C17H13F2NO4SPureza:99.24%Forma y color:SolidPeso molecular:365.35Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Forma y color:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94PT2399
CAS:PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.Fórmula:C17H10F5NO4SPureza:98.8% - 99.45%Forma y color:SolidPeso molecular:419.32Ref: TM-T12675L
1mg88,00€5mg212,00€10mg318,00€25mg575,00€50mg848,00€100mg1.189,00€1mL*10mM (DMSO)233,00€Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Fórmula:C26H52N6O11SPureza:94.68% - 99.8%Forma y color:SolidPeso molecular:656.79Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Fórmula:C8H9ClN4Pureza:99.85% - 99.86%Forma y color:Yellow Crystals White Crystalline SolidPeso molecular:196.64Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Fórmula:C8H6N2S3Pureza:98.79% - 99.77%Forma y color:SolidPeso molecular:226.34Vadadustat
CAS:Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.Fórmula:C14H11ClN2O4Pureza:99.02% - 99.80%Forma y color:SolidPeso molecular:306.7
