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HIF / HIF Prolilhidroxilasa

HIF / HIF Prolilhidroxilasa

El Factor Inducible por Hipoxia (HIF) es un factor de transcripción que desempeña un papel crucial en las respuestas celulares a bajos niveles de oxígeno (hipoxia). La actividad del HIF está regulada estrictamente por las prolil-hidroxilasas de HIF, que dirigen al HIF para su degradación en condiciones normóxicas. Los inhibidores de la prolil-hidroxilasa de HIF pueden estabilizar el HIF, promoviendo la expresión de genes involucrados en la angiogénesis, la eritropoyesis y el metabolismo. Estos inhibidores son de gran interés en el tratamiento de afecciones como la anemia, las enfermedades isquémicas y el cáncer. En CymitQuimica, ofrecemos inhibidores de HIF/prolil-hidroxilasa HIF para apoyar su investigación en biología de la hipoxia, terapia del cáncer y regulación metabólica.

Se han encontrado 142 productos de "HIF / HIF Prolilhidroxilasa"

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  • Citric acid trilithium salt tetrahydrate

    CAS:
    <p>Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of</p>
    Fórmula:C6H13Li3O11
    Pureza:99.88%
    Forma y color:White Crystalline Powder
    Peso molecular:281.98
  • Roxadustat

    CAS:
    <p>Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.</p>
    Fórmula:C19H16N2O5
    Pureza:99% - 99.88%
    Forma y color:Solid
    Peso molecular:352.34
  • Glucosamine hydrochloride

    CAS:
    <p>Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.</p>
    Fórmula:C6H13NO5·HCl
    Pureza:99.77%
    Forma y color:White Solid Crystalline
    Peso molecular:215.63
  • Hydroxycitric acid tripotassium hydrate

    CAS:
    <p>Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor effects.</p>
    Fórmula:C6H7K3O8
    Pureza:99.85%
    Forma y color:White Solid Crystalline
    Peso molecular:324.41
  • Tilorone dihydrochloride

    CAS:
    <p>Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.</p>
    Fórmula:C25H36Cl2N2O3
    Pureza:98% - 99.86%
    Forma y color:Orange Yellow Crystal Powder
    Peso molecular:483.47
  • Glucosamine

    CAS:
    <p>Glucosamine (Chitosamine) is used as a dietary supplement. Glucosamine has pharmacological effects on osteoarthritis cartilage. High-Quality, Low-Cost!</p>
    Fórmula:C6H13NO5
    Pureza:99.8% - 99.8%
    Forma y color:Coa
    Peso molecular:179.17
  • Amifostine

    CAS:
    <p>Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.</p>
    Fórmula:C5H15N2O3PS
    Pureza:99.88%
    Forma y color:White Solid
    Peso molecular:214.22
  • Albendazole

    CAS:
    <p>Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.</p>
    Fórmula:C12H15N3O2S
    Pureza:98.21% - 98.76%
    Forma y color:Colorless Crystals Solid
    Peso molecular:265.33
  • (-)-Hydroxycitric acid lactone

    CAS:
    <p>(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which</p>
    Fórmula:C6H6O7
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:190.11
  • EHP-101

    CAS:
    <p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>
    Fórmula:C28H35NO3
    Pureza:98.36%
    Forma y color:Solid
    Peso molecular:433.58
  • Chloramphenicol

    CAS:
    <p>Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.</p>
    Fórmula:C11H12Cl2N2O5
    Pureza:99.6% - 99.84%
    Forma y color:Needles Or Elongated Plates From Water Or Ethylene Dichloride Solid
    Peso molecular:323.13
  • SYP-5

    CAS:
    <p>SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.</p>
    Fórmula:C18H16O3S
    Pureza:98.31%
    Forma y color:Solid
    Peso molecular:312.38
  • Enarodustat

    CAS:
    <p>Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.</p>
    Fórmula:C17H16N4O4
    Pureza:99.73% - 99.75%
    Forma y color:Solid
    Peso molecular:340.33
  • HIF-2α-IN-2

    CAS:
    <p>HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).</p>
    Fórmula:C17H13F2NO4S
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:365.35
  • Minocycline hydrochloride

    CAS:
    <p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>
    Fórmula:C23H28ClN3O7
    Pureza:99.28% - >99.99%
    Forma y color:Bright Yellow-Orange Amorphous Solid Crystalline Yellow
    Peso molecular:493.94
  • PT2399

    CAS:
    <p>PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.</p>
    Fórmula:C17H10F5NO4S
    Pureza:98.8% - 99.45%
    Forma y color:Solid
    Peso molecular:419.32
  • Deferoxamine Mesylate

    CAS:
    <p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>
    Fórmula:C26H52N6O11S
    Pureza:94.68% - 99.8%
    Forma y color:Solid
    Peso molecular:656.79
  • Hydralazine hydrochloride

    CAS:
    <p>Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.</p>
    Fórmula:C8H9ClN4
    Pureza:99.85% - 99.86%
    Forma y color:Yellow Crystals White Crystalline Solid
    Peso molecular:196.64
  • Oltipraz

    CAS:
    <p>Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.</p>
    Fórmula:C8H6N2S3
    Pureza:98.79% - 99.77%
    Forma y color:Solid
    Peso molecular:226.34
  • Vadadustat

    CAS:
    <p>Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.</p>
    Fórmula:C14H11ClN2O4
    Pureza:99.02% - 99.80%
    Forma y color:Solid
    Peso molecular:306.7