Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.939 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
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Se han encontrado 5400 productos de "Neurociencia"
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Iclepertin
CAS:<p>Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.</p>Fórmula:C20H18F6N2O5SPureza:98.89% - 98.93%Forma y color:SolidPeso molecular:512.42LY2979165
CAS:<p>LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.</p>Fórmula:C13H22N6O6SPureza:98.41%Forma y color:SolidPeso molecular:390.42SB-224289 hydrochloride
CAS:<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Fórmula:C32H33ClN4O3Pureza:97.82% - 98.99%Forma y color:SolidPeso molecular:557.08BMS 299897
CAS:<p>BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.</p>Fórmula:C24H21ClF3NO4SPureza:99.82%Forma y color:SolidPeso molecular:511.94NB-360
CAS:<p>NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.</p>Fórmula:C21H19F4N5O2Pureza:99.72%Forma y color:SolidPeso molecular:449.4BDZ-g
CAS:<p>BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.</p>Fórmula:C21H21N5O2SPureza:99.97%Forma y color:SolidPeso molecular:407.49AChE-IN-26
CAS:<p>AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor (IC50: 0.42 μM).</p>Fórmula:C21H21BrN2O3Pureza:99.24% - 99.85%Forma y color:SoildPeso molecular:429.31Umibecestat
CAS:<p>Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.</p>Fórmula:C19H15ClF7N5O2Pureza:99.88%Forma y color:SolidPeso molecular:513.84-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS:Fórmula:C5H5N5OPureza:>93.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystallinePeso molecular:151.13(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Fórmula:C21H20BrNO6Forma y color:WhitePeso molecular:462.29YM-298198 hydrochloride
CAS:<p>mGlu1 receptor antagonist</p>Fórmula:C18H23ClN4OSPureza:98%Forma y color:SolidPeso molecular:378.919Pumosetrag Hydrochloride
CAS:<p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>Fórmula:C15H18ClN3O2SPureza:98%Forma y color:SolidPeso molecular:339.84MG 624
CAS:<p>neuronal α7 nAChR antagonist</p>Fórmula:C22H30INOForma y color:SolidPeso molecular:451.38BF 227
CAS:<p>BF 227 is a candidate for an amyloid imaging probe for PET [Ki: 4.3 nM for Aβ1-42 fibrils].</p>Fórmula:C16H16FN3O2SForma y color:SolidPeso molecular:333.38(RS)-APICA
CAS:<p>group II metabotropic glutamate receptor antagonist</p>Fórmula:C10H12NO5PForma y color:SolidPeso molecular:257.187-Desmethyl-agomelatine
CAS:<p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>Fórmula:C14H15NO2Forma y color:SolidPeso molecular:229.27Xanthocillin X permethyl ether
CAS:<p>Xanthocillin X permethyl ether, a natural product extracted from fungal sources, exhibits Aβ-42 lowering activity.</p>Fórmula:C20H16N2O2Pureza:98%Forma y color:SolidPeso molecular:316.35SB-399885 hydrochloride
CAS:<p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>Fórmula:C18H22Cl3N3O4SPureza:98%Forma y color:SolidPeso molecular:482.81Eglumegad
CAS:<p>Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).</p>Fórmula:C8H11NO4Forma y color:SolidPeso molecular:185.18Arotinolol
CAS:<p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>Fórmula:C15H21N3O2S3Forma y color:White SolidPeso molecular:371.54Ref: IN-DA003TYN
Producto descatalogadoRef: IN-DA01DQA4
Producto descatalogado1,2-Benzisoxazole-4,5,6,7-d4-3-methanesulfonamide
CAS:Fórmula:C8H4D4N2O3SPureza:CP：95%，95 atom % DForma y color:SolidPeso molecular:216.25049a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Fórmula:C22H29FO5Pureza:99%Forma y color:SolidPeso molecular:392.4611Ref: IN-DA0034IN
Producto descatalogado(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Fórmula:C24H31FO6Pureza:99%Forma y color:SolidPeso molecular:434.4977Ref: IN-DA0039HQ
Producto descatalogado11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Fórmula:C21H30O5Pureza:98%Forma y color:SolidPeso molecular:362.4599Ref: IN-DA003AAY
Producto descatalogado3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
CAS:Fórmula:C13H14N2OPureza:98%Forma y color:SolidPeso molecular:214.263111β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Fórmula:C21H28O5Pureza:98%Forma y color:SolidPeso molecular:360.4440Phosphonic acid, P-methyl-, bis(1-methylethyl) ester
CAS:Fórmula:C7H17O3PPureza:98%Forma y color:LiquidPeso molecular:180.18181-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROXPYRIDINE
CAS:Producto controladoFórmula:C12H15NPureza:95%Forma y color:SolidPeso molecular:173.2542(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione
CAS:Fórmula:C20H24O2Pureza:99%Forma y color:SolidPeso molecular:296.40343-(3,4-DIHYDROXYPHENYL-2,5,6-D3)-L-ALANINE
CAS:Fórmula:C9H8D3NO4Pureza:98%Forma y color:SolidPeso molecular:200.20642-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-onehydrochloride
CAS:Fórmula:C13H19Cl2NOPureza:98%Forma y color:SolidPeso molecular:276.2021Physostigmine
CAS:<p>Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).</p>Fórmula:C15H21N3O2Pureza:98%Forma y color:Orthorhombic Sphenoidal Prisms Or Clusters Of Leaflets From Ether Or Benzene (Anticholinesterase) Agent And As A Veterinary Medication (Epa 1998)Peso molecular:275.352-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Fórmula:C3H10NO3PPureza:98%Forma y color:SolidPeso molecular:139.091Calmodulin antagonist-1
CAS:<p>Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.</p>Fórmula:C14H18Cl2N2O2SForma y color:SolidPeso molecular:349.27Eglumegad hydrochloride
<p>Eglumegad (LY354740) hydrochloride is a potent, selective agonist for group II (mGlu2/3) receptors, showing IC50 values of 5 nM for mGlu2 and 24 nM for mGlu3 receptors in transfected human cells. This compound provides neuroprotection against NMDA-induced toxicity and exhibits anxiolytic- and antipsychotic-like properties [1].</p>Fórmula:C8H12ClNO4Forma y color:SolidPeso molecular:221.64Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.51BRL 15572
CAS:<p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>Fórmula:C25H27ClN2OForma y color:SolidPeso molecular:406.95Sarizotan
CAS:<p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>Fórmula:C22H21FN2OForma y color:SolidPeso molecular:348.421VU0080241
CAS:<p>VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).</p>Fórmula:C19H23N5Forma y color:SolidPeso molecular:321.42VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Fórmula:C18H17F2N5OSForma y color:SolidPeso molecular:389.42Ebeiedinone
CAS:<p>Ebeiedinone, a steroidal alkaloid derived from Fritillaria species, effectively inhibits the activity of human whole blood cholinesterase (ChE) at a concentration of 0.1 mM, resulting in a significant inhibitory effect of 69.0%.</p>Fórmula:C27H43NO2Forma y color:SolidPeso molecular:413.643-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Fórmula:C6H8O4Pureza:98%Forma y color:SolidPeso molecular:144.13Desmethyl cariprazine
CAS:<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Fórmula:C20H30Cl2N4OPureza:98%Forma y color:SolidPeso molecular:413.38Fluorometholone
CAS:Fórmula:C22H29FO4Pureza:>98.0%(HPLC)Forma y color:White to Orange to Green powder to crystalPeso molecular:376.47(S)-Rasagiline
CAS:<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Fórmula:C12H13NForma y color:SolidPeso molecular:171.24Ref: TM-T13252
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