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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Monoamine Oxidase B inhibitor 2


    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Fórmula:C19H19FO3
    Forma y color:Solid
    Peso molecular:314.35
  • Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Fórmula:C15H18N2O3
    Forma y color:Solid
    Peso molecular:274.315
  • ChE/Aβ1-42-IN-1


    <p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>
    Fórmula:C19H24N2O3
    Forma y color:Solid
    Peso molecular:328.41
  • nAChR antagonist 1

    CAS:
    <p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>
    Fórmula:C19H22N4O2
    Forma y color:Solid
    Peso molecular:338.4
  • AChE-IN-11


    <p>AChE-IN-11 aids Alzheimer's research, has neuroprotection/antioxidant properties (ORAC=2.5), and acts on AChE, MAO-B, BACE1 with IC50 values of 7.9-9.9 μM.</p>
    Fórmula:C18H28N2O4
    Forma y color:Solid
    Peso molecular:336.43
  • SB 258741 hydrochloride


    <p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>
    Fórmula:C19H31ClN2O2S
    Forma y color:Solid
    Peso molecular:386.98
  • CB2R/5-HT1AR agonist 1

    CAS:
    <p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>
    Fórmula:C24H33NO3
    Forma y color:Solid
    Peso molecular:383.52
  • MAO-B-IN-40

    CAS:
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Fórmula:C17H15N3O3
    Forma y color:Solid
    Peso molecular:309.319
  • YNT-3708

    CAS:
    <p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>
    Fórmula:C35H36N4O6S
    Forma y color:Solid
    Peso molecular:640.749
  • Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Fórmula:C22H24Cl3N3OS
    Forma y color:Solid
    Peso molecular:484.87
  • hMAO-B-IN-10


    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Fórmula:C16H12N4O4
    Forma y color:Solid
    Peso molecular:324.29
  • TP003

    CAS:
    <p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>
    Fórmula:C23H16F3N3O
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:407.39
  • (S)-Norfluoxetine

    CAS:
    <p>(S)-Norfluoxetine, the S enantiomer of Norfluoxetine, functions as a selective serotonin reuptake inhibitor. It enhances allopregnanolone levels and reduces aggression in socially isolated mice.</p>
    Fórmula:C16H16F3NO
    Forma y color:Solid
    Peso molecular:295.3
  • AChE/BACE1/GSK3β-IN-1


    <p>AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.</p>
    Fórmula:C26H27FN2O4
    Forma y color:Solid
    Peso molecular:450.5
  • γ-Secretase modulator 11 hydrochloride

    CAS:
    <p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>
    Fórmula:C28H23ClF2N4O2
    Forma y color:Solid
    Peso molecular:520.96
  • MAO-B-IN-10


    <p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>
    Fórmula:C23H26N2O4
    Forma y color:Solid
    Peso molecular:394.46
  • BACE1-IN-2

    CAS:
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Fórmula:C19H15F4N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:421.35
  • THRX-194556

    CAS:
    <p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>
    Fórmula:C28H41N5O5S
    Forma y color:Solid
    Peso molecular:559.721
  • (S)-Praziquantel

    CAS:
    <p>(S)-Praziquantel is the inactive isomer of R-praziquantel.</p>
    Fórmula:C19H24N2O2
    Forma y color:Solid
    Peso molecular:312.406
  • MAO-B-IN-28

    CAS:
    <p>MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.</p>
    Fórmula:C19H10F3NO4S
    Peso molecular:405.35