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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5397 productos de "Neurociencia"

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  • Tipindole

    CAS:
    <p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>
    Fórmula:C16H20N2O2S
    Forma y color:Solid
    Peso molecular:304.41
  • COX-2-IN-47

    CAS:
    <p>COX-2-IN-47 (compound 6c) is a selective inhibitor of COX-2, exhibiting an IC50 of 0.03 μM. This compound also displays antiedema activity.</p>
    Fórmula:C18H18N2O4
    Forma y color:Solid
    Peso molecular:326.35
  • VA012

    CAS:
    <p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>
    Fórmula:C21H19N3
    Forma y color:Solid
    Peso molecular:313.40
  • MAO-A/SERT-IN-1

    CAS:
    <p>MAO-A/SERT-IN-1 acts as an inhibitor for both MAO-A and the serotonin transporter (SERT). It decreases the SERT-mediated reuptake of 5-HT and demonstrates neuroprotective properties in cellular inhibition models. Additionally, this compound has shown to alleviate depressive behaviors in both zebrafish and mice.</p>
    Fórmula:C19H14N2O5
    Forma y color:Solid
    Peso molecular:350.32
  • 5-HT2A/5-HT2C inverse agonist 1

    CAS:
    <p>5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.</p>
    Fórmula:C24H35N5O2
    Forma y color:Solid
    Peso molecular:425.57
  • Flucopride

    CAS:
    <p>Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.</p>
    Fórmula:C22H33FN2O2
    Forma y color:Solid
    Peso molecular:376.51
  • R-137696

    CAS:
    <p>R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.</p>
    Fórmula:C17H23N3O2
    Forma y color:Solid
    Peso molecular:301.38
  • CaMKK2-IN-1

    CAS:
    <p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>
    Fórmula:C22H22N2O3
    Peso molecular:362.42
  • QP5020

    CAS:
    <p>QP5020 is a QPCTL inhibitor with an IC50 value of 15 nM, demonstrating antitumor efficacy.</p>
    Fórmula:C20H19FN6
    Peso molecular:362.40
  • Neral

    CAS:
    <p>Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.</p>
    Fórmula:C10H16O
    Forma y color:Solid
    Peso molecular:152.23
  • ROS151


    <p>ROS151 is an AChE inhibitor with IC50 values of 14 nM (hAChE), 1.68 μM (eqBChE), and 8.17 μM (hFAAH). Additionally, it acts as a chelating agent for Fe3+ and Cu2+. ROS151 is utilized in research related to Alzheimer's disease.</p>
    Fórmula:C18H18FN3O6
    Forma y color:Solid
    Peso molecular:391.35
  • Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Fórmula:C26H25F7N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:574.49
  • S-8510 phosphate

    CAS:
    <p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>
    Fórmula:C12H13N4O6P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:340.23
  • MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Fórmula:C16H20N2S
    Forma y color:Solid
    Peso molecular:272.408
  • 5-HT6/5-HT2AR antagonist-1


    <p>Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM &amp; 39 nM.</p>
    Fórmula:C21H26N6S
    Forma y color:Solid
    Peso molecular:394.54
  • Aβ42-IN-1

    CAS:
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Fórmula:C29H27ClN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:499
  • eeAChE-IN-1


    <p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>
    Fórmula:C27H30N6O5S
    Forma y color:Solid
    Peso molecular:550.63
  • Pareptide monohydrochloride

    CAS:
    <p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>
    Fórmula:C14H27ClN4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:334.84
  • Desmethylflunitrazepam

    CAS:
    <p>Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.</p>
    Fórmula:C15H10FN3O3
    Forma y color:Solid
    Peso molecular:299.26
  • BChE-IN-38

    CAS:
    <p>BChE-IN-38 (compound 13) is a potent BChE inhibitor, with Ki values of 62.05, 28.78, 14.09, and 1.15 nM for hCAI, hCAII, AChE, and BChE, respectively. BChE-IN-38 also demonstrates cytotoxic activity.</p>
    Fórmula:C27H20N4
    Forma y color:Solid
    Peso molecular:400.474