Tirosina quinasa / adaptadores
Los inhibidores de tirosina quinasa y adaptadores son compuestos que se dirigen a las tirosina quinasas y sus proteínas adaptadoras asociadas, las cuales desempeñan roles cruciales en la señalización celular, el crecimiento y la diferenciación. Estos inhibidores son herramientas esenciales en la investigación del cáncer, ya que muchas tirosina quinasas están involucradas en las vías de señalización que impulsan el crecimiento tumoral y la metástasis. Al inhibir las tirosina quinasas, estos compuestos pueden bloquear cascadas de señalización críticas, ofreciendo potenciales estrategias terapéuticas para varios tipos de cáncer y otras enfermedades que implican una señalización celular anormal. En CymitQuimica, ofrecemos una amplia gama de inhibidores de tirosina quinasa y adaptadores de alta calidad para apoyar su investigación en oncología, biología molecular y desarrollo de terapias dirigidas.
Subcategorías de "Tirosina quinasa / adaptadores"
- ALK(112 productos)
- CSF-1R(42 productos)
- EGFR(572 productos)
- Receptor de efrina(23 productos)
- FLT(92 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(169 productos)
- HER(5 productos)
- Hck(3 productos)
- IGF-1R(88 productos)
- PDGFR(126 productos)
- PYK2(7 productos)
- Src(79 productos)
- Receptor TAM(32 productos)
- Tie-2(20 productos)
- Receptor de Trk(59 productos)
- Tirosina quinasas(26 productos)
- VEGFR(268 productos)
- c-Fms(108 productos)
- c-Kit(101 productos)
- c-Met / HGFR(128 productos)
- c-RET(51 productos)
Mostrar 13 subcategorías más
Se han encontrado 1370 productos de "Tirosina quinasa / adaptadores"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
JNJ-10198409
CAS:<p>JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.</p>Fórmula:C18H16FN3O2Pureza:98.51%Forma y color:SolidPeso molecular:325.34Gunagratinib
CAS:<p>Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.</p>Fórmula:C22H25N5O4Pureza:99.68%Forma y color:SolidPeso molecular:423.47AG 1295
CAS:<p>AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.</p>Fórmula:C16H14N2Pureza:99.64%Forma y color:SolidPeso molecular:234.32-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
1g131,00€5g255,00€10g619,00€50g617,00€100gA consultar10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€CSF1R-IN-1
CAS:<p>CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.</p>Fórmula:C25H20F3N5O2Pureza:97.02% - 98.56%Forma y color:SolidPeso molecular:479.45(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide
CAS:Fórmula:C18H16N2O3Pureza:97%Forma y color:SolidPeso molecular:308.3312Bucladesine sodium
CAS:<p>Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.</p>Fórmula:C18H23N5NaO8PPureza:96.56% - 99.76%Forma y color:White PowderPeso molecular:491.372-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:95%Forma y color:SolidPeso molecular:360.4274Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Fórmula:C11H8N2OPureza:98%Forma y color:SolidPeso molecular:184.1940Margetuximab
CAS:<p>Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.</p>Pureza:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Forma y color:LiquidErlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Forma y color:White Or Off-White PowderPeso molecular:429.94-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1)
CAS:Fórmula:C22H23ClN3O4Pureza:98%Forma y color:SolidPeso molecular:429.8967GSK-626616
CAS:<p>GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.</p>Fórmula:C18H10Cl2N4OSPureza:98.27%Forma y color:SolidPeso molecular:401.272H-1-Benzopyran-2-one, 7,8-dihydroxy-
CAS:Fórmula:C9H6O4Pureza:95%Forma y color:SolidPeso molecular:178.14152H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS:Fórmula:C15H14N2OPureza:98%Forma y color:SolidPeso molecular:238.28454H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
CAS:Fórmula:C15H10O5Pureza:97%Forma y color:SolidPeso molecular:270.2369Ref: IN-DA00I8G3
1g26,00€5g24,00€10g31,00€1kg686,00€25g52,00€50g77,00€5kgA consultar100g114,00€10kgA consultar250g181,00€500g320,00€100mg26,00€Ref: IN-DA01DU9U
2mg112,00€5mg161,00€10mg156,00€25mg310,00€50mg701,00€100mgA consultar250mgA consultarCSF1R-IN-2
CAS:<p>CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).</p>Fórmula:C20H20FN7O2Pureza:99.29%Forma y color:SolidPeso molecular:409.42Ref: IN-DA00AP0L
1gA consultar1mg51,00€5mg68,00€10mg80,00€25mg102,00€50mg126,00€100mg193,00€250mg273,00€Methyl 2,5-Dihydroxycinnamate
CAS:Fórmula:C10H10O4Pureza:95%Forma y color:SolidPeso molecular:194.1840Emibetuzumab
CAS:<p>Emibetuzumab: potent humanized MET antibody, antitumor, inhibits HGF/MET pathways, for advanced prostate cancer research.</p>Pureza:SDS-PAGE:96.2%;SEC-HPLC:98.8%Forma y color:LiquidPeso molecular:143.74 kDaBLU-945
CAS:<p>BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.</p>Fórmula:C28H37FN6O3SPureza:99.11% - 99.16%Forma y color:SolidPeso molecular:556.7CE-245677
CAS:<p>CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.</p>Fórmula:C24H22Cl2N6O3Pureza:98.99% - 99.23%Forma y color:SolidPeso molecular:513.38Rilotumumab
CAS:<p>Rilotumumab (AMG 102) is an HGF-targeting antibody, inhibits HGF/MET signaling, and is used for CRPC and gastric cancer research.</p>Pureza:SDS-PAGE:95% SEC-HPLC:97.51%Forma y color:LiquidPeso molecular:145.2 kDaBtk inhibitor 2
CAS:<p>Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor.</p>Fórmula:C24H25N5O3Pureza:99.94%Forma y color:SolidPeso molecular:431.49AV-412
CAS:<p>AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).</p>Fórmula:C41H44ClFN6O7S2Pureza:99.85% - 99.92%Forma y color:SolidPeso molecular:851.41GIP (3-42), human
CAS:<p>Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.</p>Fórmula:C214H324N58O63SPureza:95.73%Forma y color:SolidPeso molecular:4749.35Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Forma y color:Yellow SolidPeso molecular:925.46Gancotamab
CAS:<p>Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.</p>Pureza:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Forma y color:LiquidBosutinib
CAS:<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Forma y color:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Axatilimab
CAS:<p>Axatilimab (SNDX-6352) is a human IgG4 antibody that targets CSF-1R and can be used to study immune system diseases and respiratory diseases.</p>Pureza:97.9% (SDS-PAGE); 97% (SEC-HPLC) - 97.9% (SDS-PAGE); 97% (SEC-HPLC)Forma y color:LiquidPetosemtamab
CAS:<p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.</p>Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:145.97 kDaGanitumab
CAS:<p>Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.</p>Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:145.70 kDaDasatinib monohydrate
CAS:<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Forma y color:SolidPeso molecular:506.031-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Fórmula:C25H23F3N4O2Pureza:98%Forma y color:SolidPeso molecular:468.4709O-Desmethyl gefitinib
CAS:<p>O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.</p>Fórmula:C21H22ClFN4O3Pureza:97.17%Forma y color:SolidPeso molecular:432.88Lanraplenib
CAS:<p>Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.</p>Fórmula:C23H25N9OPureza:98.35%Forma y color:SolidPeso molecular:443.5SU 5616
CAS:<p>SU 5616 (WAY-608241) regulates abnormal cell proliferation and modulates tyrosine kinase signaling.</p>Fórmula:C13H8ClNOSPureza:98.84%Forma y color:SoildPeso molecular:261.73GIP (human) acetate
<p>GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.</p>Pureza:98.65%Forma y color:SoildQuinoxaline, 6,7-dimethoxy-2-phenyl-
CAS:Fórmula:C16H14N2O2Pureza:98%Forma y color:SolidPeso molecular:266.2946Ref: IN-DA001E48
1gA consultar1mg53,00€5mg54,00€10mg73,00€25mg107,00€50mg164,00€100mg187,00€250mg503,00€Losatuxizumab
CAS:<p>Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.</p>Pureza:97.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.3% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidDuligotuzumab
CAS:<p>Duligotuzumab is a dual-targeting anti-EGFR/HER3 mAb that blocks signaling and induces ADCC for tumors with poor prognosis.</p>Pureza:95% - 95%Forma y color:LiquidCompound TPX-0046
CAS:<p>Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.</p>Fórmula:C21H21FN6O3Pureza:99.94%Forma y color:SoildPeso molecular:424.43PROTAC EGFR degrader 2
<p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>Fórmula:C58H72ClFN12O8SForma y color:SolidPeso molecular:1151.78WAY-270250
CAS:<p>WAY-270250 is an IGF-1R/SRC inhibitor.</p>Fórmula:C18H16N2O2Pureza:99.77%Forma y color:SoildPeso molecular:292.33EGFR-IN-22
CAS:<p>EGFR-IN-22: potent for EGFR (IC50: 4.91 nM) & L858R/T790M/C797S mutation (IC50: 0.54 nM).</p>Fórmula:C38H47BrFN10O2PForma y color:SolidPeso molecular:805.72
![2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluoroph…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00ICN3.webp&w=3840&q=75)
![(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA003988.webp&w=3840&q=75)
![Propanedinitrile,2-[(4-methoxyphenyl)methylene]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA007L0Q.webp&w=3840&q=75)
![2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00298W.webp&w=3840&q=75)
![1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0078T8.webp&w=3840&q=75)
