GPCR / proteína G
Los inhibidores de GPCR/proteínas G son compuestos que se dirigen a los receptores acoplados a proteínas G (GPCR) y a las proteínas G asociadas, que desempeñan roles cruciales en la transmisión de señales desde el exterior hacia el interior de las células. Estos inhibidores son esenciales para estudiar las vías de señalización mediadas por los GPCR, que están involucradas en numerosos procesos fisiológicos, incluyendo la percepción sensorial, la respuesta inmunitaria y la neurotransmisión. Los inhibidores de GPCR también son importantes en el desarrollo de fármacos, ya que muchos agentes terapéuticos tienen como objetivo estos receptores. En CymitQuimica, ofrecemos una amplia gama de inhibidores de GPCR/proteínas G de alta calidad para apoyar su investigación en farmacología, biología celular y campos relacionados.
Subcategorías de "GPCR / proteína G"
- Receptor 5-HT(1.024 productos)
- Receptor de adenosina(249 productos)
- Receptor adrenérgico(3.029 productos)
- Receptor de bombesina(35 productos)
- Receptor de bradicinina(61 productos)
- CXCR(159 productos)
- CaSR(34 productos)
- Receptor de cannabinoides(217 productos)
- Colecistoquinina(1 productos)
- Receptor de dopamina(443 productos)
- Receptor de endotelina(86 productos)
- Receptor GNRH(84 productos)
- GPCR19(33 productos)
- GRK(33 productos)
- GTPasa(22 productos)
- Receptor de glucagón(196 productos)
- Hedgehog / Smoothened(49 productos)
- Receptor de histamina(385 productos)
- Receptor LPA(21 productos)
- Receptor de melatonina(26 productos)
- Receptor de OX(42 productos)
- Receptor de opioides(326 productos)
- PAFR(14 productos)
- PKA(53 productos)
- Receptor S1P(17 productos)
- SGLT(31 productos)
- Receptor sigma(46 productos)
Mostrar 19 subcategorías más
Se han encontrado 5980 productos de "GPCR / proteína G"
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Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Fórmula:C22H21FN2OForma y color:SolidPeso molecular:348.421Propiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Fórmula:C16H25N3O·xClHPureza:99.25%Forma y color:SoildVornorexant
CAS:Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Fórmula:C23H22FN7O2Forma y color:SolidPeso molecular:447.474Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Forma y color:Odour LiquidDesmethyl cariprazine
CAS:Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Fórmula:C20H30Cl2N4OPureza:98%Forma y color:SolidPeso molecular:413.38(Rac)-Zevaquenabant
CAS:(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Fórmula:C25H21ClF3N5O2SForma y color:SolidPeso molecular:547.98Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Fórmula:C24H25FO5SPureza:98%Forma y color:SolidPeso molecular:448.54Ref: TM-T10669
Producto descatalogadoPamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Fórmula:C23H16O6Pureza:99.99%Forma y color:Fine Yellow PowderPeso molecular:388.372-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Fórmula:C11H15ClN2OPureza:98%Forma y color:SolidPeso molecular:226.7RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Fórmula:C18H22N2O5Forma y color:SolidPeso molecular:346.38Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Fórmula:C6H12Br2N4SPureza:98%Forma y color:SolidPeso molecular:332.06GR 218,231
CAS:GR 218,231 is a selective antagonist of D3 dopamine receptor.Fórmula:C24H33NO3SPureza:98%Forma y color:SolidPeso molecular:415.59Neurokinin antagonist 1
CAS:Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Fórmula:C38H40N4O3Pureza:>99.99%Forma y color:SolidPeso molecular:600.75SB251023
CAS:SB251023 is an agonist of β3-adrenoceptor.Fórmula:C28H34NO6PForma y color:SolidPeso molecular:511.55Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Fórmula:C11H12F3NOPureza:98%Forma y color:SolidPeso molecular:231.21MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Fórmula:C38H40N4O3Pureza:>99.99%Forma y color:SolidPeso molecular:600.75S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Fórmula:C25H26F3NO3Pureza:98%Forma y color:SolidPeso molecular:445.47AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Fórmula:C29H40O3Pureza:99.58%Forma y color:SolidPeso molecular:436.63Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Fórmula:C31H50O3Pureza:99.65% - >99.99%Forma y color:SolidPeso molecular:470.73Ref: TM-T27176
Producto descatalogado2-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Fórmula:C8H8N2O3SForma y color:LiquidPeso molecular:212.23
