Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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BM-1197
CAS :BM-1197, a highly potent and specific dual inhibitor of Bcl-2 and Bcl-xL, effectively targets these proteins with IC50 values of 3.5 nM and 5.2 nM for Bcl-2 andFormule :C53H59ClF4N6O7S4Couleur et forme :SolidMasse moléculaire :1131.77ReACp53
ReACp53 inhibits amyloid formation, restores p53 in cancer cells and HGSOC-derived organoids.Formule :C108H206N52O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2617.13Thalidomide-4-C3-NH2 hydrochloride
CAS :Thalidomide-4-C3-NH2 HCl is a cereblon ligand for CRBN recruitment, used to make PROTACs with a linker.Formule :C16H18ClN3O4Couleur et forme :SolidMasse moléculaire :351.785QN523
CAS :QN523 has drug-like traits, kills cancer cells in vitro, effective in vivo against pancreatic cancer, works via autophagy.Formule :C14H10N4ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :250.26Chalcones A-N-5
CAS :Chalcones A-N-5, a non-cytotoxic trihydroxy chalcone, aids cell growth & neuroprotection, inhibits ferroptosis, and targets AD research.Formule :C21H20N4O4Couleur et forme :SolidMasse moléculaire :392.41Sanggenon G
CAS :Sanggenon G inhibits XIAP by binding its BIR3 domain; affinity is 34.26 μM, boosting caspase activation.Formule :C40H38O11Couleur et forme :SolidMasse moléculaire :694.72AZD5582 dihydrochloride
CAS :Dimeric Smac mimetic inhibits XIAP, cIAP1/2 (IC50: 15/15/21 nM); binds BIR3 domain; degrades cIAPs; induces apoptosis in cancer cells; shrinks tumors in mice.Formule :C58H80Cl2N8O8Couleur et forme :SolidMasse moléculaire :1088.23Antitumor agent-41
Antitumor Agent-41 (Compound N-12) exhibits potent antitumor properties, demonstrating significant antimigration and anti-invasion activities.Formule :C64H109IN2O21Couleur et forme :SolidMasse moléculaire :1369.46LSD1-IN-26
LSD1-IN-26 (12u) is a potent LSD1 inhibitor (IC50=25.3 nM), also inhibits MAO-A/B, induces apoptosis in MGC-803, for gastric cancer research.Formule :C27H25Cl2F2N3OCouleur et forme :SolidMasse moléculaire :516.415-LOX-IN-8
5-LOX-IN-8 is a 5-LOX inhibitor with anti-inflammatory properties. It suppresses IL-6, IL-1β, TNF-α, and IFN-γ in macrophages and reduces IL-8 secretion in SW480 cells. Additionally, 5-LOX-IN-8 decreases the disease activity index in DSS colitis models. This compound is applicable for research in inflammatory bowel disease (IBD).Couleur et forme :Odour SolidThymidine 3',5'-diphosphate tetrasodium
CAS :Thymidine 3',5'-diphosphate tetrasodium inhibits staphylococcal nuclease, SND1 & tyrosyl nuclease; has anti-tumor properties & catalyzes biochemical reactions.Formule :C10H12N2Na4O11P2Couleur et forme :SolidMasse moléculaire :490.12RO5353
CAS :RO5353 is a potent and orally active inhibitor of p53-MDM2.Formule :C29H29Cl2FN4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.53PROTAC Bcl-xL ligand-1
PROTAC Bcl-xL ligand-1 serves as a ligand targeting Bcl-xL, essential in synthesizing PROTACs [1].Formule :C32H29IN4O4S2Couleur et forme :SolidMasse moléculaire :724.63Thalidomide-NH-PEG3-COOH
CAS :Thalidomide-NH-PEG3-COOH is a cereblon-based E3 ligase ligand-linker for PROTAC synthesis.Formule :C22H27N3O9Couleur et forme :SolidMasse moléculaire :477.47Anticancer agent 52
CAS :Anticancer agent 52 exhibits potent cytotoxicity, induces apoptosis, and has potential in bladder cancer research.Formule :C50H43Br2N2PCouleur et forme :SolidMasse moléculaire :862.67INF 195
CAS :INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia and myocardial infarction.Formule :C17H22ClNO3Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :323.81Thalidomide-Piperazine-PEG3-NH2
CAS :Thalidomide-Piperazine-PEG3-NH2: a cereblon ligand-linker for PROTAC E3 ligase recruitment.Formule :C25H35N5O7Couleur et forme :SolidMasse moléculaire :517.583Resistomycin
CAS :Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.
Formule :C22H16O6Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :376.36Ref: TM-T21820
1mg107,00€2mg153,00€5mg239,00€10mg353,00€25mg563,00€50mg758,00€100mg1.008,00€200mg1.359,00€Ilicicolin A
CAS :Ilicicolin A is a useful organic compound for research related to life sciences. The catalog number is T125289 and the CAS number is 22581-06-2.Formule :C23H31ClO3Couleur et forme :SolidMasse moléculaire :390.95Antibiotic DC 81
CAS :DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.Formule :C13H14N2O3Couleur et forme :SolidMasse moléculaire :246.262,4-D sodium salt
CAS :Sodium 2,4-dichlorophenoxyacetate: selective herbicide, controls broadleaf weeds by disrupting growth and protein/DNA synthesis.Formule :C8H5Cl2NaO3Couleur et forme :SolidMasse moléculaire :243.02Thalidomide-NH-C6-NH-Boc
CAS :Thalidomide-based E3 ligase ligand for PROTAC degrader MI-389 synthesis, linked to cereblon and Boc.Formule :C24H32N4O6Couleur et forme :SolidMasse moléculaire :472.542Thalidomide-5-propargyne-NH2 hydrochloride
CAS :Thalidomide derivative for CRBN protein recruitment, used in PROTACs production for protein degradation.Formule :C16H14ClN3O4Couleur et forme :SolidMasse moléculaire :347.753Thalidomide-O-C4-COOH
CAS :Thalidomide-O-C4-COOH is a synthetic E3 ligase linker derived from Thalidomide for PROTAC tech.Formule :C18H18N2O7Couleur et forme :SolidMasse moléculaire :374.3447Bromoiodoacetamide
CAS :Bromoiodoacetamide (I-HAcAm): cytotoxic, induces ROS & apoptosis in HepG-2 cells.Formule :C2H3BrINOCouleur et forme :SolidMasse moléculaire :263.86KP1019
CAS :KP1019 is now discontinued.Formule :C21H19Cl4N6RuCouleur et forme :SolidMasse moléculaire :598.30eIF4A3-IN-7
CAS :eIF4A3-IN-7: Potent eIF4A3 inhibitor, potential cancer/dysproliferation research (WO2019161345A1, Compound 8).Formule :C26H25NO7Couleur et forme :SolidMasse moléculaire :463.486Lactoferrin (17-41)
CAS :Amino acids 17-41 of lactoferrin, lactoferricin B, enhance anti-fungal effects, targeting Candida Albicans.Formule :C141H224N46O29S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3123.77Angiogenesis inhibitor 3
CAS :Angiogenesis Inhibitor 3 (compound 8) is a potent anti-cancer agent, blocking HUVEC/HCT-15 cell growth and inducing apoptosis.Formule :C44H42BrN3O9Couleur et forme :SolidMasse moléculaire :836.72Fludarabine triphosphate
CAS :Fludarabine triphosphate inhibits key enzymes, causing cell death.Formule :C10H15FN5O13P3Couleur et forme :SolidMasse moléculaire :525.17MY-943
MY-943, a potent inhibitor of tubulin polymerization and LSD1, exhibits anticancer properties by inducing G2/M phase arrest, promoting apoptosis, andFormule :C30H36N4O6S2Couleur et forme :SolidMasse moléculaire :612.763-Hydroxyterphenyllin
CAS :3-Hydroxyterphenyllin from A. candidus is a fungal compound with antioxidant, anticancer, antibacterial, and antiviral effects.Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.35LL-K9-3
CAS :LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM forFormule :C31H49N5O6S3Couleur et forme :SolidMasse moléculaire :683.94BODIPY FL thalidomide
CAS :BODIPY FL thalidomide is a fluorescent probe that binds human cereblon protein with high affinity, exhibiting a dissociation constant (Kd) of 3.6 nM [1].Formule :C37H43BF2N6O7Couleur et forme :SolidMasse moléculaire :732.58fac-[Re(CO)3(L3)(H2O)][NO3]
Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction.Formule :C25H17N6O8ReCouleur et forme :SolidMasse moléculaire :715.64Thalidomide-Piperazine 5-fluoride hydrochloride
CAS :Thalidomide-Piperazine 5-fluoride hydrochloride, a derivative of the cereblon (CRBN) inhibitor Thalidomide, serves as a ligand for E3 ubiquitin ligase (Ligands for E3 Ligase), facilitating the synthesis of PROTACs [1].Formule :C17H18ClFN4O4Couleur et forme :SolidMasse moléculaire :396.8eIF4E-IN-5
eIF4E-IN-5 (Compound 6n) is a cell-permeable eIF4E inhibitor that binds to capped mRNA, thereby inhibiting cap-dependent translation [1].Formule :C30H39Cl2N6O8PCouleur et forme :SolidMasse moléculaire :713.55Mcl-1 inhibitor 15
Mcl-1 Inhibitor 15 (Compound (Ra)-15), with a K i of 0.02 nM, is utilized in cancer research [1].Formule :C40H42ClFN6O4SCouleur et forme :SolidMasse moléculaire :757.32PD-1/PD-L1-IN-48
PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.Couleur et forme :Odour SolidNecroptosis-IN-4
Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1/2 and PDGFR-α.Couleur et forme :Odour Solid5-Fluorouracil-13C,15N2
CAS :5-Fluorouracil-13C,15N2 is a standard for quantifying 5-fluorouracil via GC/LC-MS and blocks DNA synthesis, causing cell apoptosis.Formule :C4H3FN2O2Couleur et forme :SolidMasse moléculaire :133.057EGFR/DHFR-IN-2
EGFR/DHFR-IN-2 (9b) is a dual inhibitor of h-DHFR/EGFR TK, exhibiting IC50 values of 0.192 μM for h-DHFR and 0.109 μM for EGFR. It causes cell cycle arrest at the G1/S phase and induces apoptosis. Additionally, EGFR/DHFR-IN-2 (9b) is a potential inhibitor of CYP2C9 and CYP3A4. This compound can be utilized in cancer research.Formule :C24H16N4O5Couleur et forme :SolidMasse moléculaire :440.11207Zamzetoclax
CAS :Zamzetoclax (compound 1) acts as a potential inhibitor of Mcl-1.Formule :C38H46ClN5O6SCouleur et forme :SolidMasse moléculaire :736.32Antagonist G TFA
Potent vasopressin blocker, Antagonist G TFA also mildly inhibits GRP & Bradykinin, triggers AP-1, enhances chemo response.Formule :C51H67F3N12O8SCouleur et forme :SolidMasse moléculaire :1065.21(E/Z)-Eltrombopag 13C4
CAS :(E/Z)-Eltrombopag 13C4 is a mix of E/Z isotopologues, both 13C-labeled TPO receptor agonists for thrombocytopenia.Formule :C25H22N4O4Couleur et forme :SolidMasse moléculaire :446.444GSK-1070916
CAS :GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.Formule :C30H33N7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :507.63MMRi62
CAS :MMRi62, a MDM2-MDM4 inhibitor, induces ferroptosis and autophagy in PDAC, degrades FTH1 and mutant p53, and inhibits KRAS/TP53 mutant PDAC in mice.Formule :C21H15Cl2N3ODegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :396.27Ref: TM-T60202
1mg35,00€5mg70,00€10mg104,00€25mg202,00€50mg329,00€100mg525,00€500mg1.121,00€1mL*10mM (DMSO)78,00€Ac-Trp-Glu-His-Asp-Aldehyde
CAS :Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].Formule :C28H33N7O9Couleur et forme :SolidMasse moléculaire :611.6IRF1-IN-2
CAS :IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.Formule :C18H20N2O4SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :360.43PD-L1 inhibitory peptide
CAS :PD-L1inhibitory peptide is an inhibitor peptide that targets the programmed cell death ligand 1 (PD-L1). By binding to PD-L1, it lifts immune suppression and restores the anti-tumor activity of T cells. PD-L1inhibitory peptide holds promise for use in tumor research.Formule :C96H135N21O23SCouleur et forme :SolidMasse moléculaire :1983.29CDK2-IN-45
CDK2-IN-45 is a CDK2 inhibitor with an IC50 value of 0.64 μM. It effectively inhibits the proliferation of DU-145 and PC-3 cell lines, with IC50 values of 2.20 μM and 4.17 μM, respectively. Additionally, CDK2-IN-45 induces G0/G1 phase cell cycle arrest and apoptosis. It is utilized in prostate cancer research.Formule :C25H16ClN5SCouleur et forme :SolidMasse moléculaire :453.95FAK-IN-25
FAK-IN-25 (4c) is an inhibitor of FAK with an IC50 value of 50.98 nM. It induces apoptosis and causes cell cycle arrest in the G1 phase, making it relevant for cancer research.Formule :C22H13ClN4OS2Couleur et forme :SolidMasse moléculaire :448.95PBE-AMF
PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.Couleur et forme :Odour SolidIDH1/2-IN-1
IDH1/2-IN-1 (Compound 6b) is a dual inhibitor of IDH1(R132H)/IDH2(R140Q) with IC50 values of 0.22 μM and 1.6 μM, respectively. This compound effectively inhibits tumor growth by suppressing tumor cell proliferation and activating antioxidative enzymes to enhance host defense. Additionally, IDH1/2-IN-1 reduces inflammation and promotes apoptosis, demonstrating significant anti-tumor activity. It is also utilized in leukemia research.Couleur et forme :Odour Solidd-(KLAKLAK)2, Proapoptotic Peptide
CAS :d-(KLAKLAK)2 is an antimicrobial and antitumor peptide, notable within the group of antimicrobial peptides, and exhibits strong anticancer properties. It kills bacteria by disrupting their cell membranes, causing leakage of cell contents. Additionally, d-(KLAKLAK)2 inhibits tumor cell proliferation by inducing apoptosis through mitochondrial swelling and membrane damage.Formule :C72H139N21O14Couleur et forme :SolidMasse moléculaire :1523.01MKC-1
CAS :MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formule :C22H16N4O4Degré de pureté :99.63% - 99.85%Couleur et forme :SolidMasse moléculaire :400.39Ref: TM-T9831
1mg54,00€5mg118,00€10mg168,00€25mg293,00€50mg423,00€100mg588,00€500mgÀ demander1mL*10mM (DMSO)127,00€PRMT5-IN-33
PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.Formule :C25H24BrN5O3SMasse moléculaire :553.07832PD-1/PD-L1-IN-39
PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with an IC50 value of 15.73 nM. It exhibits strong binding affinity to human and mouse PD-L1, with KD values of 14.62 and 392 nM, respectively. PD-1/PD-L1-IN-39 also demonstrates antitumor activity.Formule :C23H20ClFN2O3Masse moléculaire :426.11465WK369
WK369 is an innovative small molecule inhibitor of BCL6, demonstrating remarkable bioactivity against ovarian cancer by inducing cell cycle arrest and triggering apoptosis. It binds directly to the BCL6-BTB domain, obstructing the interaction between BCL6 and SMRT, which results in the reactivation of p53, ATR, and CDKN1A.Formule :C19H20FN5O2Masse moléculaire :369.1601S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Formule :C52H75Cl2FN6O6SMasse moléculaire :1000.48299OPBP-1
OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.Formule :C64H92N20O19SMasse moléculaire :1476.65683LZFPN-90
LZFPN-90 (LZ90) is a dual-target compound aimed at NAMPT and PD-L1. It inhibits the interaction between PD-1/PD-L1 and NAMPT activity. LZFPN-90 suppresses cell growth in a NAMPT-dependent manner, blocking the cell cycle and subsequently inducing apoptosis. Additionally, LZFPN-90 exhibits target-dependent antitumor activity, impacting metabolic processes and the immune system.Formule :C33H36N8O2SMasse moléculaire :608.26819Anticancer agent 204
Anticanceragent 204 (Compound 6) is a fluorinated derivative of cinnamamides with anticancer activity. It can arrest the cell cycle of HepG2 cells in the G1 phase and induces apoptosis by reducing mitochondrial membrane polarization (MMP) levels.Formule :C26H18FN5O3SMasse moléculaire :499.11144Necrosis inhibitor 2 (hydrocholide)
Necrosis inhibitor 2 hydrochloride (Compound B19) is an agent that inhibits cellular necrosis. It is useful for researching diseases associated with necrotic pathways, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases.Formule :C24H26ClN5O5Masse moléculaire :499.16225Thalidomide-N-C3-O-C4-O-C3-OH
Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of an E3 ligase ligand and a linker, used in the synthesis of the Aster-APROTAC degrader.Formule :C23H31N3O7Masse moléculaire :461.2162HDAC6-IN-28
HDAC6-IN-28 (compound 10C) is a potent inhibitor of HDAC6 with an IC50 of 261 nM. It significantly induces apoptosis in B16-F10 cells and causes S phase arrest. Additionally, HDAC6-IN-28 effectively increases the expression of acetylated-α-tubulin both in vitro and in vivo.Formule :C23H16FN3O2Masse moléculaire :385.12265RIPK2-IN-4
RIPK2-IN-4 is a potent and specific inhibitor of RIPK2 with an IC50 value of 5 nM.Formule :C16H10N6S2Masse moléculaire :350.04084Poly (I:C):Kanamycin (1:1)
Poly (I:C):Kanamycin (1:1) is an equimolar mixture of Poly(I:C) and kanamycin. TLR3 agonist commonly used as a vaccine adjuvant; enhanced Poly(I:C) stability.
Couleur et forme :Solid4-Nitro-3-cresol
CAS :4-Nitro-3-cresol exhibits ciliate toxicity against Tetrahymena pyriformis and is widely used in biochemical experiments and drug synthesis research.Formule :C7H7NO3Degré de pureté :99.87%Couleur et forme :Beige PowderMasse moléculaire :153.14Trimebutine
CAS :Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioidFormule :C22H29NO5Degré de pureté :99.49% - 99.86%Couleur et forme :SolidMasse moléculaire :387.47(E/Z)-LAQ824
CAS :(E/Z)-LAQ824 is an inhibitor of histone deacetylase.Formule :C22H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.46Isomahanine
Isomahanine is a useful organic compound for research related to life sciences and the catalog number is T125848.Formule :C23H25NO2Couleur et forme :SolidMasse moléculaire :347.458BDK-IN-1
BDK-IN-1 (compound (-)-43) is a BDK inhibitor with an IC50 of 0.23 μM and a maximum inhibition rate of 90%. It reduces phosphorylated-E1 levels and is useful in the study of cardiac metabolic diseases.Formule :C18H14F2N2O3SCouleur et forme :SolidMasse moléculaire :376.38Apoptosis inducer 29
Apoptosis Inducer 29 (compound Y9) demonstrates anticancer efficacy in non-small cell lung cancer by inducing lysosomal dysfunction and apoptosis, and exhibits superior performance to Gboixn both in vitro and in vivo.Formule :C33H46ClN3O3Couleur et forme :SolidMasse moléculaire :568.19Sodium propionate
CAS :Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.Formule :C3H5NaO2Couleur et forme :SoildMasse moléculaire :96.06Silicon naphthalocyanine dichloride
CAS :Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. This compound is employed in photodynamic therapy to inhibit cancer by effectively absorbing specific wavelengths of light, thereby generating oxygen radicals that aid in the destruction of cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride demonstrates promising prospects for medical applications.Formule :C48H24Cl2N8SiCouleur et forme :SolidMasse moléculaire :811.75MG-C-30
CAS :MG-C-30 is an orally active CD27 agonist with an EC50 of 0.84 μM. It activates co-stimulatory signaling in NK cells and T cells, thereby enhancing the immune response. In the EG7-OVA mouse model, MG-C-30 demonstrates antitumor activity.Formule :C24H26N4O3SCouleur et forme :SolidMasse moléculaire :450.55N-Acetylpsychosine
CAS :N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties.
Formule :C26H49NO8Couleur et forme :SolidMasse moléculaire :503.67YJ1206
CAS :YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.Formule :C49H52FN11O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :894.01SC-2001
CAS :SC-2001 inhibits MCL-1 and STAT3, enhances SHP-1, induces apoptosis in breast cancer, and counters STAT3-driven sorafenib resistance in liver cancer.Formule :C18H14BrN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.23RET-IN-28
CAS :RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.Formule :C26H29N9Couleur et forme :SolidMasse moléculaire :467.57HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65Verdinexor
CAS :Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.Formule :C18H12F6N6ODegré de pureté :98% - 99.68%Couleur et forme :SolidMasse moléculaire :442.32Ref: TM-T6123
1mg35,00€5mg111,00€10mg187,00€25mg341,00€50mg567,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)123,00€Ianalumab
CAS :Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R.Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :146.44 kDa2-Acetamidophenol
CAS :2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).
Formule :C8H9NO2Degré de pureté :>99.99%Couleur et forme :Light Brown PowderMasse moléculaire :151.16Spexin TFA
Spexin TFA: GAL2/GAL3 agonist (EC50: 45.7/112.2 nM), no activity at GAL1, reduces appetite, fatty acid uptake, and LH secretion; anxiolytic.Formule :C76H115F3N20O21SCouleur et forme :SolidMasse moléculaire :1733.9Z-Ala-Ala-Asp-CMK
CAS :Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.Formule :C19H24ClN3O7Degré de pureté :99.967%Couleur et forme :SolidMasse moléculaire :441.86RMC-9805
CAS :RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.Formule :C63H88F3N11O7Degré de pureté :98.10% - 99.92%Couleur et forme :SolidMasse moléculaire :1168.44Ref: TM-T78212
1mg127,00€5mg311,00€10mg485,00€25mg795,00€50mg1.159,00€100mg1.710,00€1mL*10mM (DMSO)687,00€ChoKα inhibitor-4
ChoKα Inhibitor-4 is a bioisosteric agent that effectively inhibits human choline kinase α1 (HChoK α1) with an IC50 of 0.66 μM.Couleur et forme :Odour SolidS-Adenosyl-L-methionine iodide
CAS :S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].Formule :C15H23IN6O5SCouleur et forme :SolidMasse moléculaire :526.35Syringolin A
CAS :Syringolin A is a useful organic compound for research related to life sciences. The catalog number is T125354 and the CAS number is 212115-96-3.
Formule :C24H39N5O6Couleur et forme :SolidMasse moléculaire :493.605Hellebrin
CAS :Cytotoxic and antiproliferative effects of Hellebrin on breast and lung cancer cells.Formule :C36H52O15Couleur et forme :SolidMasse moléculaire :724.79Spexin
CAS :Potent GAL2/GAL3 agonist (EC50 = 45.7, 112.2 nM), inactive at GAL1. Reduces appetite, fatty acid uptake in adipocytes, and LH in goldfish; anxiolytic in vivo.Formule :C74H114N20O19SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1619.9(D)-PPA 1 TFA
(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstratingFormule :C72H99F3N20O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1669.67ALK/ROS1 inhibitor 2e HCL
(R)-1-(2-((2-MeO-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(CF3O)benzyl)piperidine-3-carboxamide HCl is anti-apoptotic and anti-cancer.Formule :C30H36ClF3N6O3Degré de pureté :98.66%Couleur et forme :SoildMasse moléculaire :621.09(Iso)-Z-VAD(OMe)-FMK
CAS :(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.Formule :C22H30FN3O7Degré de pureté :97.10%Couleur et forme :SoildMasse moléculaire :467.49Asudemotide
CAS :Asudemotide is a bioactive chemical.Formule :C58H80N10O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1189.31TNF-α (46-65), human
CAS :Human TNF alpha (46-65) peptide.Formule :C110H172N24O30Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2310.69AZD5153
CAS :AZD5153 is an orally active and selective BET/BRD4 bromodomain inhibitor with an IC50 value of 1.7nM for BRD4.Formule :C25H33N7O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :479.57IDOi-Pt(IV) prodrug-1
IDOi-Pt(IV) prodrug-1 (Compound 10) is an IDOi-Pt(IV) prodrug that suppresses IDO expression. It induces apoptosis, reduces mitochondrial membrane potential, and inhibits tumor cell migration and invasion. Additionally, IDOi-Pt(IV) prodrug-1 triggers reactive oxygen species-mediated endoplasmic reticulum stress and the secretion of damage-associated molecular patterns (DAMPs), leading to immunogenic cell death (ICD). Compared to cisplatin, IDOi-Pt(IV) prodrug-1 exhibits relatively high efficiency and low toxicity in its antitumor activity.Formule :C21H26Cl3N3O6PtSCouleur et forme :SolidMasse moléculaire :749.96
