Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5593 produits trouvés pour "Apoptose"
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Thalidomide-O-C4-NH2 hydrochloride
CAS :<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Formule :C17H20ClN3O5Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :381.81Dihydrocapsaicin
CAS :<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Formule :C18H29NO3Degré de pureté :99.61% - ≥95%Couleur et forme :White CrystalMasse moléculaire :307.43Laquinimod sodium
CAS :<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Formule :C19H16ClN2NaO3Couleur et forme :SolidMasse moléculaire :378.79Enzastaurin
CAS :<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Formule :C32H29N5O2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :515.6Thalidomide-PEG4-Propargyl
CAS :<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Formule :C24H28N2O9Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :488.49PFI-1
CAS :<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.39MCB-613
CAS :<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Formule :C20H20N2ODegré de pureté :98.17% - 99.754%Couleur et forme :SolidMasse moléculaire :304.39SKLB-163
CAS :<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Formule :C18H16ClN3O2S2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :405.92Fasentin
CAS :<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Formule :C11H9ClF3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :279.64Mitoxantrone diacetate
CAS :<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Formule :C26H36N4O10Couleur et forme :SolidMasse moléculaire :564.592ONO-8130
CAS :<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Formule :C25H28N2O5S2Degré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :500.63Fedratinib
CAS :Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37Dimethyl malonate
CAS :<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Formule :C5H8O4Degré de pureté :≥95%Couleur et forme :LiquidMasse moléculaire :132.11Itanapraced
CAS :<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Formule :C16H11Cl2FO2Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :325.16Tofacitinib Citrate
CAS :<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formule :C22H28N6O8Degré de pureté :99.19% - 99.75%Couleur et forme :SolidMasse moléculaire :504.49Siremadlin
CAS :<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Formule :C26H24Cl2N6O4Degré de pureté :99.30% - 99.76%Couleur et forme :SolidMasse moléculaire :555.41Meloxicam sodium
CAS :<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Formule :C14H12N3NaO4S2Couleur et forme :SolidMasse moléculaire :373.383'-Hydroxypterostilbene
CAS :<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3Benzoylpaeoniflorin
CAS :<p>1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.</p>Formule :C30H32O12Degré de pureté :95.86% - 97.28%Couleur et forme :SolidMasse moléculaire :584.57Purvalanol A
CAS :<p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>Formule :C19H25ClN6ODegré de pureté :98.13% - 99.68%Couleur et forme :PowderMasse moléculaire :388.89Cinchonine monohydrochloride hydrate
CAS :<p>Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.</p>Formule :C19H25ClN2O2Couleur et forme :SolidMasse moléculaire :348.87Ulinastatin
CAS :<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Formule :C13H16O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.10994Droxinostat
CAS :<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Formule :C11H14ClNO3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :243.69RG7112
CAS :<p>RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.</p>Formule :C38H48Cl2N4O4SDegré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :727.788-Bromo-cAMP sodium salt
CAS :<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Formule :C10H10BrN5NaO6PDegré de pureté :98% - 99.94%Couleur et forme :Off-White PowderMasse moléculaire :430.08C5 Lenalidomide
CAS :<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Formule :C13H13N3O3Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :259.26Kinetin riboside
CAS :<p>Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)</p>Formule :C15H17N5O5Degré de pureté :98.17%Couleur et forme :White SolidMasse moléculaire :347.33Dacomitinib
CAS :<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Formule :C24H25ClFN5O2Degré de pureté :99.4% - 99.72%Couleur et forme :SolidMasse moléculaire :469.94Flupentixol dihydrochloride
CAS :<p>Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.</p>Formule :C23H27Cl2F3N2OSDegré de pureté :98.76% - >99.99%Couleur et forme :White Or Off-White SolidMasse moléculaire :507.43Shield-1
CAS :<p>Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.</p>Formule :C42H56N2O10Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :748.9Meisoindigo
CAS :<p>Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).</p>Formule :C17H12N2O2Degré de pureté :98.03% - 98.19%Couleur et forme :SolidMasse moléculaire :276.29Tazemetostat
CAS :<p>Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.</p>Formule :C34H44N4O4Degré de pureté :98.24% - ≥95%Couleur et forme :SolidMasse moléculaire :572.74Pinosylvin
CAS :<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formule :C14H12O2Degré de pureté :99.89% - 99.91%Couleur et forme :SolidMasse moléculaire :212.24Nerol
CAS :<p>Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias</p>Formule :C10H18ODegré de pureté :98.59%Couleur et forme :Colorless Oily Liquid LiquidMasse moléculaire :154.25Ricolinostat
CAS :<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formule :C24H27N5O3Degré de pureté :97.17% - 99.76%Couleur et forme :SolidMasse moléculaire :433.5Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS :<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formule :C15H16ClN3O5Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :353.76Sodium Demethylcantharidate
CAS :<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>Formule :C8H9O5·NaDegré de pureté :99.66% - ≥98%Couleur et forme :SolidMasse moléculaire :208.14BAY 61-3606 HCl
CAS :<p>BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.</p>Formule :C20H19ClN6O3Couleur et forme :SolidMasse moléculaire :426.86FB23-2
CAS :<p>FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).</p>Formule :C18H15Cl2N3O3Degré de pureté :97.29% - ≥95%Couleur et forme :SolidMasse moléculaire :392.24Thalidomide-O-amido-C6-NH2 TFA
CAS :<p>Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based</p>Formule :C46H53F6N8O16Degré de pureté :95.16%Couleur et forme :SolidMasse moléculaire :1087.95ICCB280
CAS :<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formule :C23H18N2O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :386.4M50054
CAS :<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Formule :C13H16O4Degré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :236.26Phenoxyethanol
CAS :<p>Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.</p>Formule :C8H10O2Degré de pureté :99.47%Couleur et forme :Clear To Practically Clear Colourless LiquidMasse moléculaire :138.16NSC-87877 disodium
CAS :<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Formule :C19H13N3O7S2·2NaDegré de pureté :97.89%Couleur et forme :SolidMasse moléculaire :503.42Lenaldekar
CAS :<p>Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.</p>Formule :C18H14N4Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :286.33Hederacolchiside A1
CAS :<p>Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.</p>Formule :C47H76O16Degré de pureté :98.76% - 99.92%Couleur et forme :SolidMasse moléculaire :897.1Bicyclol
CAS :<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formule :C19H18O9Degré de pureté :99.64% - 99.85%Couleur et forme :SolidMasse moléculaire :390.34Calcium dobesilate
CAS :Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Formule :C6H5O5SCa0Degré de pureté :98.39%Couleur et forme :White Or Almost PowderMasse moléculaire :229.2ZYN57939
CAS :<p>ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.</p>Formule :C28H27N7O2SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :525.62CBL0137 hydrochloride
CAS :<p>CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.</p>Formule :C21H25ClN2O2Degré de pureté :99.35% - 99.86%Couleur et forme :SolidMasse moléculaire :372.88Trametinib (DMSO solvate)
CAS :<p>Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)</p>Formule :C28H29FIN5O5SDegré de pureté :98.82% - 99.92%Couleur et forme :SolidMasse moléculaire :693.53TCS PrP Inhibitor 13
CAS :<p>TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.</p>Formule :C15H11N3O3Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :281.27Cladribine
CAS :<p>Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.</p>Formule :C10H12ClN5O3Degré de pureté :99.58% - >99.99%Couleur et forme :White Crystalline SolidMasse moléculaire :285.69Talampanel
CAS :<p>Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.</p>Formule :C19H19N3O3Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :337.37BI-847325
CAS :<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formule :C29H28N4O2Degré de pureté :97.13% - 97.54%Couleur et forme :SolidMasse moléculaire :464.56ENMD-1068 hydrochloride
CAS :<p>ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.</p>Formule :C15H30ClN3O2Couleur et forme :SolidMasse moléculaire :319.87Glycochenodeoxycholic acid sodium salt
CAS :<p>GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.</p>Formule :C26H42NNaO5Degré de pureté :95.48% - 99.82%Couleur et forme :SolidMasse moléculaire :471.61Birinapant
CAS :<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formule :C42H56F2N8O6Degré de pureté :97.08% - ≥95%Couleur et forme :SolidMasse moléculaire :806.94σ1 Receptor antagonist-1
CAS :<p>σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.</p>Formule :C21H23NOSDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :337.48IMM-01
CAS :<p>IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin</p>Formule :C12H17N3O2SDegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :267.35Topotecan
CAS :<p>Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.</p>Formule :C23H23N3O5Degré de pureté :96.14% - 98.23%Couleur et forme :Light Yellow Needle Crystal Or Crystalline PowderMasse moléculaire :421.45DRB
CAS :<p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>Formule :C12H12Cl2N2O4Degré de pureté :99.46% - 99.83%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :319.14Inauhzin
CAS :<p>Inauhzin (INZ) reactivates p53, inhibits SIRT1, induces Y cell apoptosis without genotoxic stress (IC50=3 uM in A549).</p>Formule :C25H19N5OS2Degré de pureté :98% - 99.36%Couleur et forme :SolidMasse moléculaire :469.58Tenovin-6 Hydrochloride
CAS :<p>Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.</p>Formule :C25H35ClN4O2SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :491.09S-(5'-Adenosyl)-L-methionine tosylate
CAS :<p>S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA</p>Formule :C22H30N6O8S2Degré de pureté :80% - 98.18%Couleur et forme :SolidMasse moléculaire :570.64BI 2536
CAS :<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formule :C28H39N7O3Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :521.65Oncrasin-1
CAS :<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Formule :C16H12ClNODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :269.73Bioymifi
CAS :<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>Formule :C22H12BrN3O4SDegré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :494.32Azoramide
CAS :<p>Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.</p>Formule :C15H17ClN2OSDegré de pureté :99.08% - 99.85%Couleur et forme :SolidMasse moléculaire :308.83Nobiletin
CAS :<p>Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.</p>Formule :C21H22O8Degré de pureté :98.65% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Thalidomide-5-methyl
CAS :<p>Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.</p>Formule :C14H12N2O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :272.26AZD3759 hydrochloride
CAS :<p>AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.</p>Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36PD173955
CAS :<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Formule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35Ciprofloxacin hydrochloride monohydrate
CAS :<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82RGX-202
CAS :<p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>Formule :C4H9N3O2Degré de pureté :99.67% - 99.8%Couleur et forme :SolidMasse moléculaire :131.13Laquinimod
CAS :<p>Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral</p>Formule :C19H17ClN2O3Degré de pureté :98.42% - 98.84%Couleur et forme :SolidMasse moléculaire :356.8Tenovin-3
CAS :<p>Tenovin-3 acts as a p53 activator.</p>Formule :C18H21N3OSDegré de pureté :99.72% - ≥95%Couleur et forme :SolidMasse moléculaire :327.44Neobavaisoflavone
CAS :<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formule :C20H18O4Degré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :322.35Ibandronate sodium monohydrate
CAS :<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Formule :C9H24NNaO8P2Degré de pureté :99.62%Couleur et forme :White Crystalline PowderMasse moléculaire :359.23Obatoclax Mesylate
CAS :<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>Formule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49CHR-6494 TFA
CAS :<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36MPTP hydrochloride
CAS :<p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>Formule :C12H16ClNDegré de pureté :96.35% - >99.99%Couleur et forme :SolidMasse moléculaire :209.72Demethoxycurcumin
CAS :<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Formule :C20H18O5Degré de pureté :94.54% - 99.86%Couleur et forme :SolidMasse moléculaire :338.35A-419259
CAS :<p>A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.</p>Formule :C29H34N6ODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :482.62Choline
CAS :<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Formule :C5H15NO2Degré de pureté :99.97% - ≥98%Couleur et forme :LiquidMasse moléculaire :121.18Salubrinal
CAS :<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formule :C21H17Cl3N4OSDegré de pureté :97.25% - >99.99%Couleur et forme :SolidMasse moléculaire :479.81(S)-crizotinib
CAS :<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Formule :C21H22Cl2FN5ODegré de pureté :98.52% - 99.47%Couleur et forme :SolidMasse moléculaire :450.34Ro-3306
CAS :<p>RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.</p>Formule :C18H13N3OS2Degré de pureté :97.67% - 99.79%Couleur et forme :SolidMasse moléculaire :351.45PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS :<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formule :C18H21Cl3N4ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :415.75Dienogest
CAS :<p>Dienogest (STS 557), an oral 4th-gen progestogen, is used in hormone therapy and contraception with antiandrogenic effects.</p>Formule :C20H25NO2Degré de pureté :98% - 99.43%Couleur et forme :Pale Yellow SolidMasse moléculaire :311.42Tauroursodeoxycholate
CAS :<p>Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.</p>Formule :C26H45NO6SDegré de pureté :98.77% - 99.93%Couleur et forme :White SolidMasse moléculaire :499.7PEAQX
CAS :<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Formule :C17H17BrN3O5PDegré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :454.21Copanlisib
CAS :<p>Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.</p>Formule :C23H28N8O4Degré de pureté :99% - 99.88%Couleur et forme :SolidMasse moléculaire :480.52AR42
CAS :<p>AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).</p>Formule :C18H20N2O3Degré de pureté :98.46% - 98.96%Couleur et forme :SolidMasse moléculaire :312.36Emricasan
CAS :<p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>Formule :C26H27F4N3O7Degré de pureté :98.13% - 99%Couleur et forme :SolidMasse moléculaire :569.5Aloperine
CAS :<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formule :C15H24N2Degré de pureté :98% - 99.88%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :232.361400W dihydrochloride
CAS :<p>1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).</p>Formule :C10H17Cl2N3Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :250.17Vesatolimod
CAS :<p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>Formule :C22H30N6O2Degré de pureté :97.46% - 99.03%Couleur et forme :SolidMasse moléculaire :410.51IC261
CAS :<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Formule :C18H17NO4Degré de pureté :99.45% - 99.91%Couleur et forme :SolidMasse moléculaire :311.33Bilobalide
CAS :<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formule :C15H18O8Degré de pureté :98.81% - 99.92%Couleur et forme :White SolidMasse moléculaire :326.3Evocarpine
CAS :<p>Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.</p>Formule :C23H33NODegré de pureté :99.77% - 99.819%Couleur et forme :SolidMasse moléculaire :339.51Avicularin
CAS :<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Ipatasertib
CAS :<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Formule :C24H32ClN5O2Degré de pureté :98.28% - 99.21%Couleur et forme :SolidMasse moléculaire :458Sulforaphane
CAS :<p>Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formule :C6H11NOS2Degré de pureté :95% - 99.79%Couleur et forme :Light Yellow LiquidMasse moléculaire :177.29PD146176
CAS :<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formule :C15H11NSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :237.32Bacopaside II
CAS :<p>Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.</p>Formule :C47H76O18Degré de pureté :98.14% - 99.86%Couleur et forme :SolidMasse moléculaire :929.1Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS :<p>Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase</p>Formule :C5H14Cl2N4O3Degré de pureté :99.12% - 99.84%Couleur et forme :SolidMasse moléculaire :249.10ZZW-115 hydrochloride
CAS :<p>ZZW-115 hydrochloride inhibits the activity of NUPR1.</p>Formule :C24H34Cl3F3N4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :573.97Chromium picolinate
CAS :<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Formule :C18H12CrN3O6Degré de pureté :99.64%Couleur et forme :Violet-Red Crystalline PowderMasse moléculaire :418.30Infigratinib
CAS :<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Formule :C26H31Cl2N7O3Degré de pureté :98% - 98.97%Couleur et forme :SolidMasse moléculaire :560.48Thalidomide-NH-PEG1-NH2 hydrochloride
CAS :<p>Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-</p>Formule :C17H21ClN4O5Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :396.83Trolox
CAS :<p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>Formule :C14H18O4Degré de pureté :98.90% - 99.90%Couleur et forme :White To Fainly Beige Crystalline PowderMasse moléculaire :250.29Thalidomide-NH-CH2-COOH
CAS :<p>Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a</p>Formule :C15H13N3O6Degré de pureté :96.3800%Couleur et forme :SolidMasse moléculaire :331.28Afatinib
CAS :<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formule :C24H25ClFN5O3Degré de pureté :98.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Hypericin
CAS :<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Formule :C30H16O8Degré de pureté :99.05% - ≥98%Couleur et forme :Red-Coloured Anthraquinone-DerivativeMasse moléculaire :504.44Tetrahydroxyquinone monohydrate
CAS :<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Formule :C6H6O7Couleur et forme :SolidMasse moléculaire :190.11Momordin Ic
CAS :<p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>Formule :C41H64O13Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :764.94Neferine
CAS :<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Formule :C38H44N2O6Degré de pureté :98.81% - 99.65%Couleur et forme :SolidMasse moléculaire :624.77Terrestrosin D
CAS :<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Formule :C50H80O23Degré de pureté :99.92% - 99.96%Couleur et forme :SolidMasse moléculaire :1049.16PKR-IN-C16
CAS :<p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>Formule :C13H8N4OSDegré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :268.29Apocynin
CAS :<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Formule :C9H10O3Degré de pureté :99.71% - 99.98%Couleur et forme :Yellowish To Brown PowderMasse moléculaire :166.17Levomenol
CAS :<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Formule :C15H26ODegré de pureté :96.01%Couleur et forme :Clear To Yellowish LiquidMasse moléculaire :222.37Alda-1
CAS :<p>Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.</p>Formule :C15H11Cl2NO3Degré de pureté :98.5% - 99.63%Couleur et forme :SolidMasse moléculaire :324.16Pifithrin-β hydrobromide
CAS :<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Formule :C16H17BrN2SDegré de pureté :99.24% - 99.74%Couleur et forme :SolidMasse moléculaire :349.29PIK-75
CAS :<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Formule :C16H14BrN5O4SDegré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :452.28Metamizole magnesium
CAS :<p>Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.</p>Formule :C26H32MgN6O8S2Degré de pureté :93.51%Couleur et forme :SolidMasse moléculaire :645.01ARRY 520 hydrochloride
CAS :<p>'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'</p>Formule :C20H23ClF2N4O2SDegré de pureté :98.06% - 99.62%Couleur et forme :SolidMasse moléculaire :456.94Eltrombopag Olamine
CAS :<p>Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin</p>Formule :C29H36N6O6Degré de pureté :99.59% - 99.89%Couleur et forme :SolidMasse moléculaire :564.63Epibrassinolide
CAS :<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Formule :C28H48O6Degré de pureté :97.57% - 98.11%Couleur et forme :SolidMasse moléculaire :480.68Rotenone
CAS :<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Chelidonine
CAS :<p>Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.</p>Formule :C20H19NO5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :353.37HA15
CAS :<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Formule :C23H22N4O3S2Degré de pureté :99.77% - 99.86%Couleur et forme :SolidMasse moléculaire :466.58ISRIB (trans-isomer)
CAS :<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Formule :C22H24Cl2N2O4Degré de pureté :97.86% - 99.27%Couleur et forme :SolidMasse moléculaire :451.34SGI-1027
CAS :<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Thalidomide 4-fluoride
CAS :<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Formule :C13H9FN2O4Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :276.22AZ 628
CAS :<p>AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.</p>Formule :C27H25N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :451.52Thalidomide-O-amido-C6-NH2 hydrochloride
CAS :<p>Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.</p>Formule :C21H27ClN4O6Degré de pureté :97.33%Couleur et forme :SolidMasse moléculaire :466.915CA-4948
CAS :<p>CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.</p>Formule :C24H25N7O5Degré de pureté :99.35% - 99.88%Couleur et forme :SolidMasse moléculaire :491.5Tenovin-6
CAS :<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Formule :C25H34N4O2SDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :454.63Dacarbazine citrate
CAS :<p>Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.</p>Formule :C12H18N6O8Couleur et forme :SolidMasse moléculaire :374.31Ganetespib
CAS :<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Formule :C20H20N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :364.4FOXO4-DRI acetate
<p>FOXO4-DRI acetate is a bioactive chemical.</p>Formule :C36H64N14O14SDegré de pureté :99.10%Couleur et forme :SolidMasse moléculaire :5358.06(1E,6E)-Bis(demethoxy)curcumin
CAS :<p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>Formule :C19H16O4Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :308.33Periplocin
CAS :<p>Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.</p>Formule :C36H56O13Degré de pureté :99.66% - 99.74%Couleur et forme :SolidMasse moléculaire :696.82Genistein
CAS :<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24TrxR1-IN-B19
CAS :<p>TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress</p>Formule :C21H22O5Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :354.4Thalidomide-O-amido-C3-NH2 TFA
CAS :<p>Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.</p>Formule :C20H21F3N4O8Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :502.4Thalidomide-O-COOH
CAS :<p>Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.</p>Formule :C15H12N2O7Degré de pureté :98% - 98.29%Couleur et forme :SolidMasse moléculaire :332.27Cyasterone
CAS :<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Formule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Formosanin C
CAS :<p>Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.</p>Formule :C51H82O20Degré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :1015.18Wogonin
CAS :<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Triptolide
CAS :<p>Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.</p>Formule :C20H24O6Degré de pureté :97.19% - 99.97%Couleur et forme :White To Off-White SolidMasse moléculaire :360.4Volasertib
CAS :<p>Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.</p>Formule :C34H50N8O3Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :618.81FIN56
CAS :<p>FIN56 is a specific inducer of ferroptosis.</p>Formule :C25H31N3O5S2Degré de pureté :99.72% - 99.78%Couleur et forme :SolidMasse moléculaire :517.66Calycosin
CAS :<p>Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).</p>Formule :C16H12O5Degré de pureté :99.91% - >99.99%Couleur et forme :White PowderMasse moléculaire :284.26MG 149
CAS :<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formule :C22H28O3Degré de pureté :98.69% - 99.86%Couleur et forme :SolidMasse moléculaire :340.46VER-50589
CAS :<p>VER-50589 is a potent HSP90 inhibitor.</p>Formule :C19H17ClN2O5Degré de pureté :99.96% - >99.99%Couleur et forme :SolidMasse moléculaire :388.8Methoxychlor
CAS :<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Formule :C16H15Cl3O2Degré de pureté :98.82% - ≥95%Couleur et forme :Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfMasse moléculaire :345.65Aminopurvalanol A
CAS :<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Formule :C19H26ClN7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :403.91Betulin
CAS :<p>Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.</p>Formule :C30H50O2Degré de pureté :98.52% - 99.88%Couleur et forme :White Crystalline PowderMasse moléculaire :442.72CPI1189
CAS :<p>CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.</p>Formule :C13H18N2O2Degré de pureté :98.34% - 99.51%Couleur et forme :SolidMasse moléculaire :234.29Apomine
CAS :<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Formule :C28H52O7P2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :562.66GW779439X
CAS :<p>GW779439X is an inhibitor of CDK.</p>Formule :C22H21F3N8Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :454.45Liproxstatin-1 hydrochloride
CAS :<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Formule :C19H22Cl2N4Couleur et forme :SolidMasse moléculaire :377.31GSK778 hydrochloride
CAS :<p>GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.</p>Formule :C30H34ClN5O3Degré de pureté :97.26% - 98.35%Couleur et forme :SolidMasse moléculaire :548.08Sirtinol
CAS :<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Thalidomide-4-OH
CAS :<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formule :C13H10N2O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :274.23Thalidomide-NH-C4-NH-Boc
CAS :<p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>Formule :C22H28N4O6Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :444.48Difurazon hydrochloride
CAS :<p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>Formule :C14H13ClN6O6Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :396.74Methoxyamine HCl
CAS :<p>Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.</p>Formule :CH6ClNODegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :83.51TVB-3166
CAS :<p>TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).</p>Formule :C24H24N4ODegré de pureté :99.53% - 99.57%Couleur et forme :SolidMasse moléculaire :384.47Larotrectinib sulfate
CAS :<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formule :C21H22F2N6O2·H2O4SDegré de pureté :98.62% - 99.76%Couleur et forme :SolidMasse moléculaire :526.51Linderalactone
CAS :<p>1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.</p>Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.292'-OMe-Guanosine
CAS :<p>2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.</p>Formule :C11H15N5O5Degré de pureté :99.93%Couleur et forme :White SolidMasse moléculaire :297.27Alogliptin Benzoate
CAS :<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Formule :C25H27N5O4Degré de pureté :99.94% - >99.99%Couleur et forme :White PowderMasse moléculaire :461.51Cynaroside
CAS :<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formule :C21H20O11Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :448.38PI-1840
CAS :<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.47Capmatinib xHCl
CAS :<p>Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50</p>Formule :C23H18ClFN6ODegré de pureté :98.62% - 99.81%Couleur et forme :SolidMasse moléculaire :448.89LY-294002 hydrochloride
CAS :<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formule :C19H17NO3·HClDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :343.81A-1155463
CAS :<p>A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2, BCL-W and MCL-1.</p>Formule :C35H32FN5O4S2Degré de pureté :96.1% - 99%Couleur et forme :SolidMasse moléculaire :669.79Zinc Protoporphyrin
CAS :<p>Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.</p>Formule :C34H32N4O4ZnDegré de pureté :95.43% - 99.27%Couleur et forme :SolidMasse moléculaire :626.02OICR-9429
CAS :<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Formule :C29H32F3N5O3Degré de pureté :97.07% - 99.93%Couleur et forme :SolidMasse moléculaire :555.59Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS :<p>Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.</p>Formule :C25H31F3N4O11Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :620.54Bigelovin
CAS :<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formule :C17H20O5Degré de pureté :99.61% - 99.72%Couleur et forme :SolidMasse moléculaire :304.34KRCA-0008
CAS :<p>KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.</p>Formule :C30H37ClN8O4Degré de pureté :96.19%Couleur et forme :SolidMasse moléculaire :609.12Perhexiline
CAS :<p>Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.</p>Formule :C19H35NCouleur et forme :SolidMasse moléculaire :277.49Ketorolac hemicalcium
CAS :<p>Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.</p>Formule :C30H24CaN2O6Couleur et forme :SolidMasse moléculaire :548.608Thalidomide-propargyl
CAS :<p>Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.</p>Formule :C16H12N2O5Degré de pureté :95.14%Couleur et forme :SolidMasse moléculaire :312.28Thalidomide-NH-C6-NH2 hydrochloride
CAS :<p>Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.</p>Formule :C19H25ClN4O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :408.88Britannin
CAS :<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formule :C19H26O7Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :366.41Verteporfin
CAS :<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Sulfaphenazole
CAS :<p>Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for</p>Formule :C15H14N4O2SDegré de pureté :97.53% - 99.67%Couleur et forme :SolidMasse moléculaire :314.36L-Ascorbic acid sodium salt
CAS :<p>L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.</p>Formule :C6H7NaO6Degré de pureté :98.73% - 99.75%Couleur et forme :Less Solid PowderMasse moléculaire :198.11PK11000
CAS :<p>PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.</p>Formule :C6H5ClN2O4SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :236.63Abacavir monosulfate
CAS :<p>Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.</p>Formule :C14H20N6O5SCouleur et forme :SolidMasse moléculaire :384.41Benidipine hydrochloride
CAS :<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03(ZE)-SU9516
CAS :<p>(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.</p>Formule :C13H11N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :241.25PKCβ inhibitor 1
CAS :<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Formule :C24H21N5O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :411.46Diclofenac Potassium
CAS :<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Formule :C14H10Cl2KNO2Degré de pureté :99.51%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :334.24
