Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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Selumetinib
CAS :Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.Formule :C17H15BrClFN4O3Degré de pureté :98.1% - 99.90%Couleur et forme :White Or Pale White SolidMasse moléculaire :457.68DPN
CAS :DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formule :C15H13NO2Degré de pureté :99.01%Couleur et forme :Off-White SolidMasse moléculaire :239.27(-)-Epipodophyllotoxin
CAS :(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.Formule :C22H22O8Degré de pureté :99.72% - 99.97%Couleur et forme :SolidMasse moléculaire :414.41α-Mangostin
CAS :alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.Formule :C24H26O6Degré de pureté :98.22% - 99.84%Couleur et forme :Yellow PowderMasse moléculaire :410.46Kobe0065
CAS :Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Formule :C15H11ClF3N5O4SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :449.79Apitolisib
CAS :Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Formule :C23H30N8O3SDegré de pureté :98.28% - 99.64%Couleur et forme :SolidMasse moléculaire :498.6ASK1-IN-2
CAS :ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.Formule :C19H17FN6ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :364.38physalin F
CAS :Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.Cost-effective and quality-assured.Formule :C28H30O10Degré de pureté :99.5% - 99.61%Couleur et forme :SolidMasse moléculaire :526.53Kaempferol
CAS :Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Formule :C15H10O6Degré de pureté :98% - 99.41%Couleur et forme :Yellow Needles From Alcohol And Water SolidMasse moléculaire :286.24PU02
CAS :PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.Formule :C16H12N4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :292.36SP2509
CAS :SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).Formule :C19H20ClN3O5SDegré de pureté :98.82% - 99.53%Couleur et forme :SolidMasse moléculaire :437.9Pinosylvin
CAS :Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formule :C14H12O2Degré de pureté :99.89% - 99.91%Couleur et forme :SolidMasse moléculaire :212.24BMS-202
CAS :BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.Formule :C25H29N3O3Degré de pureté :97.92% - 99.66%Couleur et forme :SolidMasse moléculaire :419.52PD173074
CAS :PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Ref: TM-T2642
5mg40,00€10mg54,00€1mL*10mM (DMSO)56,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€LYN-1604
CAS :LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formule :C33H43Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.62JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg48,00€1mL*10mM (DMSO)94,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€Fimepinostat
CAS :Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formule :C23H24N8O4SDegré de pureté :98.27% - 99.87%Couleur et forme :SolidMasse moléculaire :508.55Ref: TM-T2078
2mg44,00€5mg66,00€1mL*10mM (DMSO)74,00€10mg92,00€25mg172,00€50mg295,00€100mg485,00€500mg1.035,00€Boc-Asp(OMe)-fluoromethyl ketone
CAS :Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Formule :C11H18FNO5Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :263.26Valinomycin
CAS :Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormule :C54H90N6O18Degré de pureté :95.37% - 97.16%Couleur et forme :White SolidMasse moléculaire :1111.32Ginsenoside Rg1
CAS :Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Formule :C42H72O14Degré de pureté :99% - 99.92%Couleur et forme :White Crystalline PowderMasse moléculaire :801.01MGCD-265 analog
CAS :Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formule :C26H20FN5O2S2Degré de pureté :98.06% - 98.68%Couleur et forme :SolidMasse moléculaire :517.6Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :509.67BMS-1001
CAS :BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formule :C35H34N2O7Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :594.7Ref: TM-T8470
1mg58,00€5mg124,00€1mL*10mM (DMSO)172,00€10mg177,00€25mg299,00€50mg424,00€100mg587,00€200mg792,00€AZD0156
CAS :AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.Formule :C26H31N5O3Degré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :461.56(S)-10-Hydroxycamptothecin
CAS :(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formule :C20H16N2O5Degré de pureté :99.09% - 99.81%Couleur et forme :SolidMasse moléculaire :364.35Suramin Sodium Salt
CAS :Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formule :C51H34N6Na6O23S6Degré de pureté :97.47% - 99.97%Couleur et forme :WhiteMasse moléculaire :1429.15Perifosine
CAS :Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formule :C25H52NO4PDegré de pureté :99.80 - >99.99%Couleur et forme :SolidMasse moléculaire :461.66Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€Palmatine
CAS :Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formule :C21H22NO4Degré de pureté :96.28% - 99.49%Couleur et forme :SolidMasse moléculaire :352.4WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22NSC 66811
CAS :NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formule :C23H20N2ODegré de pureté :96.94%Couleur et forme :SolidMasse moléculaire :340.42DMU-212
CAS :DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.Formule :C18H20O4Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :300.35Ref: TM-T36674
2mg34,00€5mg50,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg152,00€50mg259,00€100mg385,00€500mg873,00€Xanthohumol
CAS :Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-Formule :C21H22O5Degré de pureté :98.19% - 99.67%Couleur et forme :Orange PowderMasse moléculaire :354.40Navtemadlin
CAS :Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.Formule :C28H35Cl2NO5SDegré de pureté :95.55% - 99.08%Couleur et forme :SolidMasse moléculaire :568.55SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg54,00€1mL*10mM (DMSO)59,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€Lithocholic acid
CAS :Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formule :C24H40O3Degré de pureté :98% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.664EGI-1
CAS :4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formule :C18H12Cl2N4O4SDegré de pureté :96.8% - 99.12%Couleur et forme :SolidMasse moléculaire :451.28AZ960
CAS :AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formule :C18H16F2N6Degré de pureté :96.02% - 99.88%Couleur et forme :SolidMasse moléculaire :354.36NU 7026
CAS :NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFormule :C17H15NO3Degré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :281.31CASIN
CAS :CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formule :C20H22N2ODegré de pureté :98.18% - >99.99%Couleur et forme :SolidMasse moléculaire :306.4Ref: TM-T3971
1mg35,00€2mg50,00€5mg71,00€1mL*10mM (DMSO)71,00€10mg114,00€25mg178,00€50mg268,00€100mg413,00€500mg888,00€Xanthatin
CAS :Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3MK-886
CAS :MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formule :C27H34ClNO2SDegré de pureté :99.23% - 99.84%Couleur et forme :SolidMasse moléculaire :472.08Ref: TM-T6893
1mg34,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg105,00€25mg205,00€50mg334,00€100mg512,00€200mg732,00€Kynurenic acid sodium
CAS :Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.Formule :C10H6NNaO3Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :211.15OTS514 hydrochloride
CAS :OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).Formule :C21H20N2O2S·HClDegré de pureté :99.67% - 99.84%Couleur et forme :SolidMasse moléculaire :400.92Ref: TM-T4134
1mg58,00€2mg92,00€5mg165,00€1mL*10mM (DMSO)165,00€10mg290,00€25mg527,00€50mg710,00€100mg898,00€500mg1.791,00€Alginic acid
CAS :Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formule :C14H22O13Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :398.317G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Ref: TM-T8742
1mg35,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€Fedratinib hydrochloride hydrate
CAS :Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formule :C27H40Cl2N6O4SDegré de pureté :98.96% - 99.87%Couleur et forme :SolidMasse moléculaire :615.61Epothilone A
CAS :Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.Formule :C26H39NO6SDegré de pureté :99.89% - 99.92%Couleur et forme :SolidMasse moléculaire :493.66
