Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
Affichez 10 plus de sous-catégories
3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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SB-743921 hydrochloride
CAS :<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.525-Chloro-2'-deoxyuridine
CAS :<p>5-Chloro-2'-deoxyuridine (5-Chlorodeoxyuridine) is a thymine analog.</p>Formule :C9H11ClN2O5Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :262.65SRI-29329
CAS :<p>SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).</p>Formule :C20H26ClN7Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :399.92Reversine
CAS :<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Formule :C21H27N7ODegré de pureté :98% - 98.42%Couleur et forme :SolidMasse moléculaire :393.49NSC23005
CAS :<p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>Formule :C13H17NO4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :283.34CDK9-IN-30
CAS :<p>CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.</p>Formule :C16H20FNO3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :293.33Lifitegrast
CAS :<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48TH287 hydrochloride
CAS :<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formule :C11H11Cl3N4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :305.59ILK-IN-3
CAS :<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24Peldesine dihydrochloride
CAS :<p>Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.</p>Formule :C12H13Cl2N5OCouleur et forme :SolidMasse moléculaire :314.17THZ1 Hydrochloride
<p>THZ1 Hydrochloride: selective covalent CDK7 inhibitor, IC50 of 3.2 nM; affects CDK12/13 & lowers MYC expression.</p>Formule :C31H29Cl2N7O2Couleur et forme :SolidMasse moléculaire :602.51Temozolomide Acid
CAS :<p>TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.</p>Formule :C6H5N5O3Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :195.14ZM-447439
CAS :<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.596-Chloropurine riboside
CAS :<p>6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.</p>Formule :C10H11ClN4O4Degré de pureté :96.84%Couleur et forme :SoildMasse moléculaire :286.6700Chroman 1 dihydrochloride
<p>Chroman 1 dihydrochloride: potent ROCK2 inhibitor (IC50: 1 pM), also affects ROCK1 (52 pM) and MRCK (150 nM).</p>Formule :C24H30Cl2N4O4Couleur et forme :SolidMasse moléculaire :509.43Cyclo(RADfK)
CAS :<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.72'-Deoxy-N2-methylguanosine
CAS :<p>2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.</p>Formule :C11H15N5O4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :281.27BC-1471
CAS :<p>BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.</p>Formule :C27H32N4O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :508.635-Hydroxyuridine
CAS :<p>5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.</p>Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.22'-Deoxy-N4-methylcytidine
CAS :<p>2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.</p>Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24Muromonab
CAS :<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Degré de pureté :95% - 97.51% (SEC-HPLC)Couleur et forme :LiquidEtaracizumab
CAS :<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Degré de pureté :96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.3 (kDa)O6-Methyldeoxy guanosine
CAS :<p>O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.</p>Formule :C11H15N5O4Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :281.27Rabacfosadine
CAS :<p>Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.</p>Formule :C21H35N8O6PDegré de pureté :99.06% - 99.37%Couleur et forme :SolidMasse moléculaire :526.53N6-Methyl-2'-O-methyladenosine
CAS :<p>N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found</p>Formule :C12H17N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :295.29N6-(p-Methoxybenzyl)adenosine
CAS :<p>Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormone</p>Formule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39DS44960156
CAS :<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Formule :C20H15NO5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.349-(β-D-Xylofuranosyl)adenine
CAS :<p>9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has</p>Formule :C10H13N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :267.242'-O-(2-Methoxyethyl)adenosine
CAS :<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32P-2'-deoxyribose
CAS :<p>P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.</p>Formule :C11H15N3O5Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :269.25PolQi2
CAS :<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Formule :C21H16ClN5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :453.9LSN2839567
CAS :<p>LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.</p>Formule :C25H28F2N8Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :478.542'-C-β-Methylguanosine
CAS :<p>2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.</p>Formule :C11H15N5O5Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :297.275'-O-DMT-N4-Bz-5-Me-dC
CAS :<p>5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.</p>Formule :C38H37N3O7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :647.725-Bromouridine
CAS :<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Formule :C9H11BrN2O6Degré de pureté :99.89%Couleur et forme :White PowderMasse moléculaire :323.1CDK12-IN-5
CAS :<p>CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.</p>Formule :C18H15F5N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :454.36Braco-19
CAS :<p>Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.</p>Formule :C35H43N7O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :593.763'-Deoxy-3'-fluoroadenosine
CAS :<p>3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne</p>Formule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.23ARB-272572
CAS :<p>ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.</p>Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.675-Bromo-2',3',5'-tri-O-acetyluridine
CAS :<p>5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.</p>Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.212'-O-Methyl-2-thiouridine
CAS :<p>2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.</p>Formule :C10H14N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :274.292'-Deoxy-2-iodoadenosine
CAS :<p>2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.</p>Formule :C10H12IN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :377.14RO0270608
CAS :<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.78Bexotegrast
CAS :<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.61AZ5576
CAS :<p>AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].</p>Formule :C21H24FN3O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :385.43Z62954982
CAS :<p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>Formule :C20H21N3O5SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :415.46N6-(2-Hydroxyethyl)adenosine
CAS :<p>N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.</p>Formule :C12H17N5O5Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :311.29PDD00017273
CAS :<p>PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.</p>Formule :C23H26N6O4S2Degré de pureté :99.14% - 99.21%Couleur et forme :SolidMasse moléculaire :514.622',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS :<p>2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.</p>Formule :C21H40N2O6Si2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.72SCH-1473759 hydrochloride
CAS :<p>SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).</p>Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463MK-5108
CAS :<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.94Mps1-IN-2
CAS :<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Formule :C26H36N6O3Degré de pureté :96.24% - 99.75%Couleur et forme :SolidMasse moléculaire :480.65-Methyl-5,6-dihydrouridine
CAS :<p>5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.</p>Formule :C10H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.24Vatelizumab
CAS :<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Degré de pureté :95%Couleur et forme :LiquidLinvoseltamab
CAS :<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Couleur et forme :LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Degré de pureté :98%Couleur et forme :Odour LiquidDHX9-IN-8
CAS :<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Formule :C18H16N2O3S2Couleur et forme :SolidMasse moléculaire :372.46Obrindatamab
CAS :<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Couleur et forme :LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Degré de pureté :95%Couleur et forme :Odour LiquidRinatabart
CAS :<p>Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.</p>Degré de pureté :95% - 95%Couleur et forme :Odour LiquidVVD-214
CAS :<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Formule :C20H21F2N3O4SDegré de pureté :99.24%Couleur et forme :SoildMasse moléculaire :437.46Vepsitamab
CAS :<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Couleur et forme :LiquidRovelizumab
CAS :<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Couleur et forme :LiquidUbamatamab
CAS :<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Couleur et forme :LiquidPacanalotamab
CAS :<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Couleur et forme :LiquidPasotuxizumab
CAS :<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Couleur et forme :LiquidFlotetuzumab
CAS :<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Couleur et forme :LiquidEnlimomab
CAS :<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Couleur et forme :LiquidVoxalatamab
CAS :<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Couleur et forme :LiquidLocked nucleic acid 1
CAS :<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Formule :C32H32N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.61Cevostamab
CAS :<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Couleur et forme :LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Degré de pureté :99%Couleur et forme :Odour LiquidMetribuzin
CAS :<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Formule :C8H14N4OSDegré de pureté :99.07%Couleur et forme :Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Masse moléculaire :214.29N6-Etheno 2'-deoxyadenosine
CAS :<p>N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.</p>Formule :C12H13N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.26Vibecotamab
CAS :<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Couleur et forme :LiquidPOSH-IN-1
CAS :<p>POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.</p>Formule :C14H8FNO3SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :289.28Tepoditamab
CAS :<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Couleur et forme :LiquidVonsetamig
CAS :<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Couleur et forme :LiquidPavurutamab
CAS :<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Couleur et forme :LiquidGresonitamab
CAS :<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Couleur et forme :LiquidGSK4418959
CAS :<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Formule :C31H30F4N4O5SDegré de pureté :99.141%Couleur et forme :SoildMasse moléculaire :646.65D-F07
CAS :<p>D-F07 is a novel fluorescent IRE-1 RNase inhibitor and a tricyclic chromone with potential anticancer activity.</p>Formule :C18H21NO6Degré de pureté :98.31% - 99.31%Couleur et forme :SoildMasse moléculaire :347.36Mirvetuximab soravtansine
CAS :<p>Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancer</p>Degré de pureté :6mg/ml - 6mg/mlCouleur et forme :LiquidMasse moléculaire :150000 (average)2'-Azido-2'-deoxyuridine
CAS :<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Formule :C9H11N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.21L-Threonolactone
CAS :<p>L-Threonolactone is a Carbohydrate Derivative.</p>Formule :C4H6O4Couleur et forme :SolidMasse moléculaire :118.09Adenosine 2'-PEG-Biotin
CAS :<p>Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.</p>Formule :C26H40N8O8SCouleur et forme :SolidMasse moléculaire :624.71E-982
CAS :<p>E-982 is derived from the reference compound.</p>Formule :C25H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.58RI(dl)-2 TFA
CAS :RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formule :C19H17N3Couleur et forme :SolidMasse moléculaire :287.36hDHODH-IN-2
CAS :<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Formule :C19H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.349SB273005
CAS :<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.44(R)-(+)-O-Demethylbuchenavianine
CAS :<p>(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.</p>Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.40XL413
CAS :<p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>Formule :C14H12ClN3O2Degré de pureté :98.40% - >99.99%Couleur et forme :SolidMasse moléculaire :289.72Mps1-IN-1
CAS :<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Formule :C28H33N5O4SDegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :535.66BAY1217389
CAS :<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Formule :C27H24F5N5O3Degré de pureté :98.14% - 99.42%Couleur et forme :SolidMasse moléculaire :561.53,4-Dihydroxybenzylamine hydrobromide
CAS :<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formule :C7H10BrNO2Degré de pureté :98.49%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06Tirofiban
CAS :<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formule :C22H36N2O5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :440.6LIMK1 inhibitor BMS-4
CAS :<p>BMS-4 is a LIMK inhibitor targeting LIMK1/2, reduces cofilin phosphorylation, noncytotoxic to A549 cells.</p>Formule :C23H23N7O2SCouleur et forme :SolidMasse moléculaire :461.54DENV-IN-7
CAS :<p>DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.</p>Formule :C24H22O8Couleur et forme :SolidMasse moléculaire :438.43BSJ-01-175
CAS :<p>BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.</p>Formule :C30H33ClN6O2Couleur et forme :SolidMasse moléculaire :545.08Digeranyl bisphosphonate
CAS :<p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>Formule :C21H34Na4O6P2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :536.4
