
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(116 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(233 produits)
- HSP(180 produits)
- Intégrine(276 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(128 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(77 produits)
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3935 produits trouvés pour "Cycle cellulaire/point de contrôle"
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NG 52
CAS :NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Formule :C16H19ClN6ODegré de pureté :98% - 99.34%Couleur et forme :SolidMasse moléculaire :346.817BIO
CAS :7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17GS-441524 HCl
CAS :GS-441524: Inhibits FIP virus, EC50 at 0.78 μM, precursor to active triphosphate, non-toxic up to 100 μM, works at ≥1 μM, metabolite of Remdesivir.Formule :C12H14ClN5O4Couleur et forme :SolidMasse moléculaire :327.72FDI-6
CAS :FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and downregulates FOXM1-activated genes.Formule :C19H11F4N3OS2Degré de pureté :98.92% - >99.99%Couleur et forme :SolidMasse moléculaire :437.43Ref: TM-T4005
1mg34,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg192,00€50mg274,00€100mg408,00€200mg597,00€Bohemine
CAS :Bohemine is a cyclin-dependent kinase inhibitor.Formule :C18H24N6ODegré de pureté :99.09% - 99.53%Couleur et forme :SolidMasse moléculaire :340.42Nemorubicin HCL
CAS :Nemorubicin HCL, a PNU152243A salt, acts on resistant tumors via topoisomerase I inhibition and targets NER pathway upregulated cells.Formule :C32H38ClNO13Couleur et forme :SolidMasse moléculaire :680.1ML-7 hydrochloride
CAS :ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM);Formule :C15H18ClIN2O2SDegré de pureté :99% - 99.26%Couleur et forme :White PowderMasse moléculaire :452.74Ref: TM-T3050
2mg34,00€5mg47,00€1mL*10mM (DMSO)52,00€10mg71,00€25mg141,00€50mg230,00€100mg334,00€200mg434,00€Tozasertib
CAS :Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.59Ganciclovir sodium
CAS :Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22CID-797718
CAS :CID-797718 is a protein kinase D1 (PKD1) inhibitor.Formule :C12H11NO3Degré de pureté :98.91% - 99.21%Couleur et forme :SolidMasse moléculaire :217.22Ref: TM-T1858
1mg62,00€5mg138,00€1mL*10mM (DMSO)152,00€10mg200,00€25mg339,00€50mg482,00€100mg665,00€200mg893,00€MNS
CAS :MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formule :C9H7NO4Degré de pureté :98.53%Couleur et forme :Yellow PowderMasse moléculaire :193.16MTOB
CAS :MTOB, a CtBP substrate, inhibits CtBP-linked cancer activity in cells/mice and regulates TCF-4, affecting CSC proliferation.Formule :C5H7NaO3SDegré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :170.16SBC-115337
CAS :SBC-115337 is a PCSK9 inhibitor.Formule :C29H19N3O4Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :473.48URMC-099
CAS :URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formule :C27H27N5Degré de pureté :99.32% - 99.98%Couleur et forme :SolidMasse moléculaire :421.54APY29
CAS :APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.Formule :C17H16N8Degré de pureté :96.51% - 98.46%Couleur et forme :SolidMasse moléculaire :332.36Ref: TM-T3654
2mg40,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg90,00€25mg167,00€50mg285,00€100mg515,00€500mg1.071,00€TP-353
CAS :TP-353 (EOS-61973) is a CDK7 inhibitor.Formule :C35H30FNO3Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :531.62Ref: TM-T22440
1mg43,00€5mg80,00€1mL*10mM (DMSO)105,00€10mg129,00€25mg225,00€50mg314,00€100mg432,00€200mg597,00€THZ1 Hydrochloride
THZ1 Hydrochloride: selective covalent CDK7 inhibitor, IC50 of 3.2 nM; affects CDK12/13 & lowers MYC expression.Formule :C31H29Cl2N7O2Couleur et forme :SolidMasse moléculaire :602.51Simeprevir
CAS :Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Formule :C38H47N5O7S2Degré de pureté :99.45% - 99.92%Couleur et forme :SolidMasse moléculaire :749.94M2N12
CAS :M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formule :C20H16ClN5O2Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :393.83Ref: TM-T11929
1mg84,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg447,00€50mg670,00€100mg982,00€MLN8054 sodium
CAS :MLN8054 sodium is an Aurora A inhibitor.Formule :C25H14ClF2N4NaO2Couleur et forme :SolidMasse moléculaire :498.84Metoprine
CAS :Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.Formule :C11H10Cl2N4Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :269.13WR99210 hydrochloride(47326-86-3 free base)
CAS :WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Formule :C14H19Cl4N5O2Degré de pureté :97.77% - 99.8%Couleur et forme :SolidMasse moléculaire :431.14Ref: TM-T17257L
1mg62,00€5mg132,00€1mL*10mM (DMSO)157,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€WNK-IN-11
CAS :WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Formule :C21H21Cl2N5OSDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :462.4Ref: TM-T5456
1mg87,00€5mg172,00€1mL*10mM (DMSO)188,00€10mg280,00€25mg474,00€50mg683,00€100mg964,00€500mg1.918,00€Aplidine
CAS :Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).Formule :C57H87N7O15Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :1110.34Ref: TM-T9715
1mg235,00€5mg588,00€10mg787,00€1mL*10mM (DMSO)938,00€25mg1.216,00€50mg1.568,00€100mg2.527,00€Clevudine
CAS :Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.Formule :C10H13FN2O5Degré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :260.22Lurbinectedin
CAS :Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formule :C41H44N4O10SDegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :784.873'-Deoxyguanosine
CAS :3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Formule :C10H13N5O4Degré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :267.24Carotegrast methyl HCl
CAS :Carotegrast methyl (AJM300/PTC-100) is an oral α4 integrin blocker reducing inflammation and experimental colitis.Formule :C25H20Cl3N3O5Couleur et forme :SolidMasse moléculaire :548.801CID755673
CAS :CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Formule :C12H11NO3Degré de pureté :97.68% - 99.84%Couleur et forme :SolidMasse moléculaire :217.22AT7519 TFA
CAS :AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.Formule :C18H18Cl2F3N5O4Couleur et forme :SolidMasse moléculaire :496.27Favipiravir
CAS :Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Formule :C5H4FN3O2Degré de pureté :97.32% - 99.90%Couleur et forme :SolidMasse moléculaire :157.1SNS-314 Mesylate
CAS :SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formule :C18H15ClN6OS2·CH4O3SDegré de pureté :99.44% - 99.92%Couleur et forme :SolidMasse moléculaire :527.04Levofloxacin hydrochloride
CAS :Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.8Phosphonoformic acid trisodium salt hexa
CAS :Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.Formule :CH12Na3O11PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.03NU2058
CAS :NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.Formule :C12H17N5ODegré de pureté :99.34% - 99.92%Couleur et forme :SolidMasse moléculaire :247.3Ref: TM-T3186
10mg42,00€1mL*10mM (DMSO)47,00€25mg78,00€50mg106,00€100mg160,00€200mg230,00€500mg378,00€LY3143921
CAS :LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].Formule :C16H12FN5OCouleur et forme :SolidMasse moléculaire :309.3Cyclo(RGDyK) trifluoroacetate
CAS :Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47SAR-020106
CAS :SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.Formule :C19H19ClN6ODegré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :382.85PfDHODH-IN-1
CAS :PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24Ref: TM-T12438
1mg52,00€1mL*10mM (DMSO)92,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€GAK inhibitor 49 hydrochloride
Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.Formule :C20H23ClN2O5Couleur et forme :SolidMasse moléculaire :406.86Tirapazamine
CAS :Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Formule :C7H6N4O2Degré de pureté :96.65% - 99.87%Couleur et forme :Orange-Red Crystalline PowderMasse moléculaire :178.152'-Fluoro-2'-Deoxyadenosine
CAS :2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formule :C10H12FN5O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :269.23DHFR-IN-3
CAS :DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Formule :C8H7BrN4Degré de pureté :99.521% - 99.65%Couleur et forme :SolidMasse moléculaire :239.07EN4
CAS :EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Formule :C25H24N2O4Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :416.47Activated Protein C (390-404), human acetate
Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.Formule :C93H134N22O25Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :1960.19BSJ-03-123
CAS :BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.Formule :C47H56N10O11Degré de pureté :97.78% - 99.38%Couleur et forme :SolidMasse moléculaire :937.01Ref: TM-T5395
1mg87,00€2mg113,00€5mg177,00€10mg259,00€25mg409,00€50mg560,00€100mg800,00€500mg1.611,00€NSAH
CAS :NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-Formule :C18H14N2O3Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :306.32BI-1347
CAS :BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formule :C22H20N4ODegré de pureté :96.7% - 99.63%Couleur et forme :SolidMasse moléculaire :356.42Ref: TM-T5405
1mg40,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg126,00€25mg240,00€50mg439,00€100mg647,00€500mg1.359,00€LDN-192960 hydrochloride
CAS :LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.Formule :C18H22Cl2N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35COH29
CAS :COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Formule :C22H16N2O5SDegré de pureté :97.04% - 98.92%Couleur et forme :SolidMasse moléculaire :420.44Ref: TM-T3157
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€Fialuridine
CAS :Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.88%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09Tipiracil hydrochloride
CAS :Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formule :C9H12Cl2N4O2Degré de pureté :98.13% - ≥95%Couleur et forme :SolidMasse moléculaire :279.12CHR-6494 TFA
CAS :CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36Ref: TM-T9521
1mg60,00€5mg122,00€1mL*10mM (DMSO)142,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€SRI-29329
CAS :SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Formule :C20H26ClN7Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :399.92THZ2
CAS :THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Formule :C31H28ClN7O2Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :566.05NSC23005
CAS :NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).Formule :C13H17NO4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :283.34E7820
CAS :E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37Ref: TM-T4435
1mg34,00€2mg49,00€5mg65,00€1mL*10mM (DMSO)80,00€10mg84,00€25mg137,00€50mg200,00€100mg321,00€200mg477,00€Lifitegrast
CAS :Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48Mitonafide
CAS :Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.Formule :C16H15N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :313.31Ref: TM-T25817
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg178,00€50mg295,00€100mg484,00€200mg690,00€500mg1.035,00€TH287 hydrochloride
CAS :TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.Formule :C11H11Cl3N4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :305.59ILK-IN-3
CAS :ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24CCG-203971
CAS :CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formule :C23H21ClN2O3Degré de pureté :98.82% - 99.50%Couleur et forme :SolidMasse moléculaire :408.88Cyclo(RADfK)
CAS :Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.7RI-1
CAS :RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formule :C14H11Cl3N2O3Degré de pureté :99.3% - 99.62%Couleur et forme :SolidMasse moléculaire :361.61CCG-222740
CAS :CCG-222740 is an inhibitor of Rho/MRTF pathwayFormule :C23H19ClF2N2O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :444.86Ref: TM-T7764
2mg39,00€5mg62,00€1mL*10mM (DMSO)66,00€10mg94,00€25mg172,00€50mg260,00€100mg371,00€200mg530,00€TMPyP4 tosylate
CAS :TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formule :C72H66N8O12S4Degré de pureté :98.61% - 99.85%Couleur et forme :SolidMasse moléculaire :1363.6PHA-767491
CAS :PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.Formule :C12H11N3ODegré de pureté :99.49% - >99.99%Couleur et forme :SolidMasse moléculaire :213.24Ref: TM-T6206
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg64,00€25mg92,00€50mg138,00€100mg197,00€200mg295,00€STF-083010
CAS :STF-083010 is a selective inhibitor of the IRE1α endonuclease.Formule :C15H11NO3S2Degré de pureté :98.09% - 99.45%Couleur et forme :SolidMasse moléculaire :317.38Ref: TM-T6681
5mg49,00€1mL*10mM (DMSO)55,00€10mg75,00€25mg114,00€50mg193,00€100mg349,00€200mg527,00€500mg767,00€Trilaciclib
CAS :Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Formule :C24H30N8ODegré de pureté :99.624%Couleur et forme :SolidMasse moléculaire :446.55Madrasin
CAS :Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formule :C16H17N5O2Degré de pureté :99.06% - 99.61%Couleur et forme :SolidMasse moléculaire :311.34JSH-150
CAS :JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Formule :C24H33ClN6O2SDegré de pureté :99.96% - 99.96%Couleur et forme :SolidMasse moléculaire :505.08Dimethylenastron
CAS :Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formule :C16H18N2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :302.39Ref: TM-T3118
1mg34,00€2mg46,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg93,00€25mg147,00€50mg222,00€100mg334,00€SCH900776 (S-isomer)
CAS :SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formule :C15H18BrN7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :376.25Ref: TM-T3700
1mg50,00€2mg66,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg146,00€25mg250,00€50mg403,00€100mg593,00€Cilengitide
CAS :Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66iRGD peptide
CAS :iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04THZ531
CAS :THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formule :C30H32ClN7O2Degré de pureté :97.17% - 99.86%Couleur et forme :SolidMasse moléculaire :558.07Ref: TM-T4293
1mg59,00€2mg86,00€5mg105,00€1mL*10mM (DMSO)130,00€10mg144,00€25mg313,00€50mg447,00€100mg650,00€500mg1.341,00€IXA4
CAS :IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Formule :C24H28N4O4Degré de pureté :99.8% - 99.85%Couleur et forme :SolidMasse moléculaire :436.5BRD32048
CAS :BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.Formule :C16H22N6ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :314.39Ref: TM-T23820
1mL*10mM (DMSO)44,00€2mg50,00€5mg105,00€10mg172,00€25mg304,00€50mg485,00€100mg782,00€200mg1.054,00€SBC-115076
CAS :SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.Formule :C31H33N3O5Degré de pureté :97.07% - 99.89%Couleur et forme :SolidMasse moléculaire :527.61Ref: TM-T2626
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg94,00€25mg172,00€50mg309,00€100mg477,00€500mg1.063,00€Pyridostatin
CAS :Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormule :C31H32N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.64LY2880070
CAS :LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.Formule :C19H23N7O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :381.43Phthalazinone pyrazole
CAS :Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34Sarecycline free base
CAS :Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.Formule :C24H29N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.5WEE1-IN-3
CAS :WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.Formule :C28H31N7O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :497.59Ref: TM-T8916
1mg66,00€5mg147,00€1mL*10mM (DMSO)161,00€10mg225,00€25mg398,00€50mg532,00€100mg767,00€200mg1.018,00€Alisertib
CAS :Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formule :C27H20ClFN4O4Degré de pureté :98.31% - >99.99%Couleur et forme :SolidMasse moléculaire :518.92Ref: TM-T2241
5mg52,00€1mL*10mM (DMSO)59,00€10mg92,00€25mg146,00€50mg215,00€100mg334,00€200mg430,00€500mg705,00€IMM-H007
CAS :IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormule :C22H23N5O8Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :485.45Ref: TM-T9010
1mg38,00€5mg92,00€1mL*10mM (DMSO)124,00€10mg128,00€25mg215,00€50mg304,00€100mg411,00€200mg570,00€BMS-265246
CAS :BMS-265246 is a potent and selective CDK1/2 inhibitor.Formule :C18H17F2N3O2Degré de pureté :99.25% - 99.57%Couleur et forme :SolidMasse moléculaire :345.34Ref: TM-T2679
1mg34,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg110,00€25mg210,00€50mg318,00€100mg455,00€200mg617,00€Bredinin aglycone
CAS :Bredinin aglycone (SM-108) is a purine nucleotide analog.Formule :C4H5N3O2Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :127.1LIMK-IN-22j
CAS :LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.Formule :C20H21BrN8Degré de pureté :99.165%Couleur et forme :SolidMasse moléculaire :453.34KB-0742 dihydrochloride
CAS :KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.Formule :C16H27Cl2N5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :360.33Ref: TM-T9446
1mg90,00€2mg136,00€5mg222,00€1mL*10mM (DMSO)235,00€10mg358,00€25mg597,00€50mg850,00€100mg1.153,00€Atuveciclib
CAS :Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Formule :C18H18FN5O2SDegré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :387.43Ref: TM-T10464L
1mg84,00€2mg114,00€5mg192,00€1mL*10mM (DMSO)212,00€10mg313,00€25mg580,00€50mg773,00€100mg1.063,00€PTC-209 hydrobromide
CAS :PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in
Formule :C17H13Br2N5OS·HBrDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :576.1Ref: TM-T6178
1mg37,00€5mg78,00€1mL*10mM (DMSO)89,00€10mg124,00€25mg265,00€50mg465,00€100mg753,00€200mg1.035,00€Afuresertib hydrochloride
CAS :Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Formule :C18H18Cl3FN4OSDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :463.8Ref: TM-T7885
2mg49,00€5mg71,00€1mL*10mM (DMSO)81,00€10mg89,00€25mg155,00€50mg240,00€100mg414,00€200mg538,00€Abemaciclib methanesulfonate
CAS :Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).
Formule :C27H32F2N8·CH4O3SDegré de pureté :98.69% - 99.44%Couleur et forme :SolidMasse moléculaire :602.7Carotegrast methyl
CAS :Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formule :C28H26Cl2N4O5Degré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :569.44Rabusertib
CAS :Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.
Formule :C18H22BrN5O3Degré de pureté :98.86% - 99.87%Couleur et forme :SolidMasse moléculaire :436.3YKL-5-124
CAS :YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFormule :C28H33N7O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :515.61Ref: TM-T22461
1mg82,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg222,00€25mg385,00€50mg560,00€100mg790,00€MC180295
CAS :MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formule :C17H18N4O3SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :358.41Ref: TM-T5533
1mg52,00€5mg124,00€1mL*10mM (DMSO)136,00€10mg177,00€25mg301,00€50mg424,00€100mg605,00€200mg797,00€RAD51-IN-1
CAS :Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formule :C22H16ClN3ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :373.83

