
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
Affichez 10 plus de sous-catégories
3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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10-Formyl-5,8-dideazafolic acid
CAS :<p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>Formule :C22H21N5O7Degré de pureté :96.04%Couleur et forme :SolidMasse moléculaire :467.43RSK-IN-1
CAS :<p>RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].</p>Formule :C22H17NO2Couleur et forme :SolidMasse moléculaire :327.38CDK9-IN-15
CAS :<p>CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.</p>Formule :C16H11N3OSDegré de pureté :97.24%Couleur et forme :SolidMasse moléculaire :293.34CTP Synthetase-IN-1
CAS :<p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>Formule :C20H19F3N6O3S2Degré de pureté :98.11% - 99.18%Couleur et forme :SolidMasse moléculaire :512.53SP-471P
CAS :<p>SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.</p>Formule :C33H26BrN5O2Couleur et forme :SolidMasse moléculaire :604.515(S)-HpETE
CAS :<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Crisnatol
CAS :<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Formule :C23H23NO2Couleur et forme :SolidMasse moléculaire :345.43Cdc7-IN-17
CAS :<p>Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].</p>Formule :C13H15N5OSCouleur et forme :SolidMasse moléculaire :289.36CDK2-IN-13
CAS :<p>CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.</p>Formule :C13H12ClN5Couleur et forme :SoildMasse moléculaire :273.72CCG-257081
CAS :<p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>Formule :C24H19ClF3N3O2Degré de pureté :99.76% - 99.94%Couleur et forme :SolidMasse moléculaire :473.87GW8510
CAS :<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Formule :C21H15N5O3S2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :449.51CBL 0100 free base
CAS :<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Formule :C24H26N2O2Degré de pureté :98.18% - 98.86%Couleur et forme :SolidMasse moléculaire :374.483'-Deoxyuridine-5'-triphosphate
CAS :<p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.</p>Formule :C9H15N2O14P3Couleur et forme :SolidMasse moléculaire :468.14CDK8-IN-7
CAS :<p>CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.</p>Formule :C30H40N2Couleur et forme :SolidMasse moléculaire :428.65XVA143
CAS :<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formule :C25H21Cl2N3O8Couleur et forme :SolidMasse moléculaire :562.36IDD388
CAS :<p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63Laromustine
CAS :<p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>Formule :C6H14ClN3O5S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :307.78HBV-IN-4
CAS :<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Formule :C24H19ClFN5O3Couleur et forme :SolidMasse moléculaire :479.89APC 366
CAS :<p>APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).</p>Formule :C22H28N6O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :440.5MLAF50
CAS :<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Formule :C15H12I2O4Couleur et forme :SolidMasse moléculaire :510.06Cdc7-IN-15
CAS :<p>Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].</p>Formule :C12H14N4OSCouleur et forme :SolidMasse moléculaire :262.33CP681301
CAS :<p>CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.</p>Formule :C17H22N4OCouleur et forme :SolidMasse moléculaire :298.38DNA Gyrase-IN-2
CAS :<p>DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.</p>Formule :C24H24N8OS2Couleur et forme :SolidMasse moléculaire :504.63CDK7-IN-15
CAS :<p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>Formule :C21H24F4N6OSCouleur et forme :SolidMasse moléculaire :484.51DHODH-IN-15
CAS :<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Formule :C15H11N3O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :281.27Beaucage reagent
CAS :<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Formule :C7H4O3S2Degré de pureté :98.50%Couleur et forme :White To Off-White PowderMasse moléculaire :200.23WNK1-IN-1
CAS :<p>WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.</p>Formule :C13H15BrCl2N2O4SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :446.14DNA Gyrase-IN-3
CAS :<p>DNA Gyrase-IN-3 inhibits E. coli DNA gyrase B with IC50 5.41-15.64 μM; shows anti-TB and antibacterial properties.</p>Formule :C18H20N6OS2Couleur et forme :SolidMasse moléculaire :400.52Valategrast hydrochloride
CAS :<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41CH-1504
CAS :<p>CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.</p>Formule :C23H23N5O5Couleur et forme :SolidMasse moléculaire :449.46MMV688844
CAS :<p>MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.</p>Formule :C23H25ClN4O2Couleur et forme :SolidMasse moléculaire :424.92CDK7-IN-10
CAS :<p>CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>Formule :C29H35N7O3Couleur et forme :SolidMasse moléculaire :529.63CDK7-IN-16
CAS :<p>CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.</p>Formule :C19H21F3N6O2SCouleur et forme :SolidMasse moléculaire :454.47Y-33075
CAS :<p>Y-33075 (Y-39983 free base) is a ROCK inhibitor that lowers IOP, increases blood flow to ONH, and increases the number of RGCs with regenerating axons.</p>Formule :C16H16N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :280.32DHX9-IN-1
CAS :<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Formule :C21H21F2N5O3SCouleur et forme :SolidMasse moléculaire :461.49Tripolin A
CAS :<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Formule :C15H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.255-OHdU
CAS :<p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>Formule :C9H12N2O6Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :244.2DENV-IN-4
CAS :<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Formule :C28H32N4O4SiCouleur et forme :SolidMasse moléculaire :516.66CDK9-IN-14
CAS :<p>CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.</p>Formule :C21H23F2N3O4Couleur et forme :SolidMasse moléculaire :419.42ST7612AA1
CAS :<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Formule :C20H27N3O4SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :405.518-Azido-ADP disodium
CAS :<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Formule :C10H13N8NaO10P2Couleur et forme :SolidMasse moléculaire :490.197Triaziquone
CAS :<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Formule :C12H13N3O2Couleur et forme :SolidMasse moléculaire :231.25FAK/aurora kinase-IN-1
CAS :<p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>Formule :C23H24ClN7O3Couleur et forme :SolidMasse moléculaire :481.93tBID
CAS :<p>tBID is a selective homeodomain-interacting protein kinase 2 (HIPK2) inhibitor (IC50 of 0.33 μM)</p>Formule :C11H3Br4N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.78P18IN003
CAS :<p>P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of</p>Formule :C17H16N2O3Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :296.32Cdc7-IN-3
CAS :<p>Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.</p>Formule :C20H22N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.41LCAHA
CAS :<p>LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.</p>Formule :C24H41NO3Couleur et forme :SolidMasse moléculaire :391.59Flurocitabine
CAS :<p>Flurocitabine is a therapeutic agent with antineoplastic activity.</p>Formule :C9H10FN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.19DHFR-IN-5
CAS :<p>DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.</p>Formule :C18H24N4O4Couleur et forme :SolidMasse moléculaire :360.41FN-1501-propionic acid
CAS :<p>FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.</p>Formule :C25H27N9O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.54Zelpolib
CAS :<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Formule :C22H21N3O5S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :471.5510-Methyl-10-deazaaminopterin
CAS :<p>10-Methyl-10-deazaaminopterin is a folate analog that shows antitumor activity.</p>Formule :C21H23N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.45N2-Ethylguanosine
CAS :<p>N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Formule :C12H17N5O5Couleur et forme :SolidMasse moléculaire :311.29Y-9738
CAS :<p>Y-9738 is an agent of hypolipidemic.</p>Formule :C15H16ClNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :309.74NSC 693868
CAS :<p>CDKs and GSK-3 inhibitor</p>Formule :C9H7N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :185.19Zaurategrast ethyl ester sulfate
CAS :<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formule :C56H60Br2N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1197.01HBV-IN-22
CAS :<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Formule :C26H29N3O2S2Couleur et forme :SolidMasse moléculaire :479.66NSC666715
CAS :<p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>Formule :C15H13Cl2N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.33ROCK2-IN-5
<p>ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.</p>Formule :C23H25N3O5SCouleur et forme :SolidMasse moléculaire :455.53S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS :<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Formule :C12H16N2O2S2Couleur et forme :SolidMasse moléculaire :284.4Aurora A/PKC-IN-1
CAS :<p>Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.</p>Formule :C16H14N6OSe2Couleur et forme :SolidMasse moléculaire :464.24KIRA-7
CAS :<p>KIRA-7: imidazopyrazine, anti-fibrotic, inhibits IRE1α RNase (IC50: 110 nM) allosterically.</p>Formule :C27H23FN6OCouleur et forme :SolidMasse moléculaire :466.51DHODH-IN-1
CAS :<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formule :C21H20F3N3O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :403.4BRD9185
CAS :<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formule :C23H21F6N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.42Zaurategrast ethyl ester
CAS :<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formule :C28H29BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.46DHFR-IN-2
CAS :<p>DHFR-IN-2 (4e) is a potent MtDHFR uncompetitive inhibitor with a 7 μM IC50, promising for TB research.</p>Formule :C14H13NO2Couleur et forme :SolidMasse moléculaire :227.26(E/Z)-BIO-acetoxime
CAS :<p>(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.</p>Formule :C18H12BrN3O3Couleur et forme :SolidMasse moléculaire :398.21Capzimin
CAS :<p>Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.</p>Formule :C30H24N6O2S4Degré de pureté :98.31% - 99.32%Couleur et forme :SolidMasse moléculaire :628.818-Deazahomofolic acid
CAS :<p>8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Formule :C21H22N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.44A 65281
CAS :<p>A 65281: antibacterial isothiazoloquinolone, inhibits P4-unknotting, induces DNA breakage via topoisomerase II.</p>Formule :C17H16F2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.4MFH290
CAS :<p>MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.</p>Formule :C26H31N5O3S2Couleur et forme :SolidMasse moléculaire :525.69RHI002-Me
CAS :<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Formule :C18H19N3O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.49Direct Black 38 free acid
CAS :<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Formule :C34H27N9O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :737.77ROCK-IN-D2
CAS :<p>ROCK-IN-D2 is an effective and selective inhibitor of ROCK.</p>Formule :C22H28N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.5Atuveciclib S-Enantiomer
CAS :<p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>Formule :C18H18FN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43RET-IN-19
CAS :<p>RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.</p>Formule :C28H28N6O4SCouleur et forme :SolidMasse moléculaire :544.62(R)-Filanesib
CAS :<p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>Formule :C20H22F2N4O2SCouleur et forme :SolidMasse moléculaire :420.48Apricitabine
CAS :<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Formule :C8H11N3O3SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :229.26PD 130883
CAS :<p>PD 130883 is a potent lipophilic quinazoline antifolate.</p>Formule :C18H15N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.34RP-106
CAS :<p>RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.</p>Formule :C17H19N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.35A 65282
CAS :<p>A 65282: antibacterial isothiazoloquinolone, inhibits P4-unknotting, causes DNA breaks via topoisomerase II.</p>Formule :C17H16F2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.4CDK8-IN-10
CAS :<p>CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.</p>Formule :C25H15ClF3N5O3Couleur et forme :SolidMasse moléculaire :525.87CDK4/6-IN-8
CAS :<p>CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).</p>Formule :C18H18N6O5Couleur et forme :SolidMasse moléculaire :398.37IMB-10
CAS :<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formule :C19H15NOS2Couleur et forme :SolidMasse moléculaire :337.46CRT5
CAS :<p>CRT5, a selective PKD inhibitor, blocks VEGF effects on histone deacetylase 5, CREB, HSP27, and endothelial functions. IC50s: 1-2 nM for PKD1-3.</p>Formule :C28H30N4O2Couleur et forme :SolidMasse moléculaire :454.56AnnH31
CAS :<p>AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the</p>Formule :C15H13N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :251.28hDHODH-IN-4
CAS :<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Formule :C21H24N4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :364.44SC-203885
CAS :<p>SC-203885 is a checkpoint kinase 2 inhibitor.</p>Formule :C15H13N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.3DHODH-IN-24
CAS :<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Formule :C26H26N4Couleur et forme :SolidMasse moléculaire :394.51Kira8 Hydrochloride
CAS :<p>Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.</p>Formule :C31H30Cl2N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :637.58Clociguanil
CAS :<p>Clociguanil has antimalarial activity.</p>Formule :C12H15Cl2N5OCouleur et forme :SolidMasse moléculaire :316.19CDK4/6-IN-12
CAS :<p>CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM & 3090 nM, useful in cancer research.</p>Formule :C12H10N6Couleur et forme :SolidMasse moléculaire :238.25Tenofovir exalidex
CAS :<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Formule :C28H52N5O5PDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :569.72BPIC
CAS :<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Formule :C27H20N2O5Couleur et forme :SolidMasse moléculaire :452.46Levofloxacin sodium
CAS :<p>Levofloxacin sodium: synthetic antibacterial, stops DNA replication by inhibiting bacterial DNA gyrase.</p>Formule :C18H20FN3NaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.363FRα-IN-1
CAS :<p>FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.</p>Formule :C21H24N6O6Couleur et forme :SolidMasse moléculaire :456.45CLK1-IN-2
<p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>Formule :C16H12Cl2N2O2SCouleur et forme :SolidMasse moléculaire :367.25TDRL-X80
CAS :<p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>Formule :C23H15ClN2O6Couleur et forme :SolidMasse moléculaire :450.83Metioprim
CAS :<p>Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.</p>Formule :C14H18N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.38XL-188
CAS :<p>XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.</p>Formule :C32H42N6O4Couleur et forme :SolidMasse moléculaire :574.71
