Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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Emlenoflast
CAS :<p>Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.</p>Formule :C19H24N4O3SDegré de pureté :97.004% - 98.19%Couleur et forme :SolidMasse moléculaire :388.48MALT1-IN-3
CAS :<p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>Formule :C21H19F3N8O2Couleur et forme :SolidMasse moléculaire :472.42Edasalonexent
CAS :<p>Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.</p>Formule :C31H42N2O3Degré de pureté :99.13% - >99.99%Couleur et forme :SolidMasse moléculaire :490.68Emlenoflast sodium
CAS :<p>Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,</p>Formule :C19H24N4NaO3SCouleur et forme :SolidMasse moléculaire :411.47MK-0703
CAS :<p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>Formule :C17H22O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.42Bay 65-1942 hydrochloride
CAS :<p>Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.</p>Formule :C22H26ClN3O4Couleur et forme :SolidMasse moléculaire :431.91Insulin levels modulator
CAS :<p>Insulin level regulators can be used to treat diabetes.</p>Formule :C21H23N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.52COX-2/5-LOX-IN-1
CAS :<p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 & 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>Formule :C14H10ClN3O4S2Couleur et forme :SolidMasse moléculaire :383.83IKKβ-IN-1
CAS :<p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>Formule :C31H30N4O4SCouleur et forme :SolidMasse moléculaire :554.66MIND4-17
CAS :<p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>Formule :C20H15N5O3SCouleur et forme :SolidMasse moléculaire :405.43IRAK4-IN-21
CAS :<p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>Formule :C28H28FN7O2Couleur et forme :SolidMasse moléculaire :513.57MitoB
CAS :<p>MitoB is a novel exon of mitochondrial hydrogen peroxide.</p>Formule :C25H23BBrO2PCouleur et forme :SolidMasse moléculaire :477.14Heterophdoid A
CAS :<p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>Formule :C26H42O10Couleur et forme :SolidMasse moléculaire :514.61Ruzotolimod
CAS :<p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections （WO2021130195A1）[1].</p>Formule :C14H18N4O5SCouleur et forme :SolidMasse moléculaire :354.38COX-2/15-LOX-IN-1
CAS :<p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>Formule :C21H21N7S3Couleur et forme :SolidMasse moléculaire :467.63Clopirac
CAS :<p>Clopirac is a potent and orally active prostaglandin synthetase inhibitor that is an anti-inflammatory agent [1].</p>Formule :C14H14ClNO2Couleur et forme :SolidMasse moléculaire :263.72NF-κB-IN-2
CAS :<p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>Formule :C15H18O3Couleur et forme :SolidMasse moléculaire :246.3Gue1654
CAS :<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Formule :C23H17N3OS3Degré de pureté :98.02% - 98.04%Couleur et forme :SolidMasse moléculaire :447.6AVE3085
CAS :<p>AVE3085 is an enhancer of endothelial nitric oxide synthase that restores endothelial function and lowers blood pressure in spontaneously hypertensive rats.</p>Formule :C17H13F2NO3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :317.29Methyl aminolevulinate
CAS :<p>Methyl aminolevulinate, a prodrug for protoporphyrin IX, sensitizes in PDT.</p>Formule :C6H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :145.16Dihydrolipoic acid
CAS :<p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>Formule :C8H16O2S2Degré de pureté :97.51%Couleur et forme :Yellow To Orange LiquidMasse moléculaire :208.34TPO agonist 1
CAS :<p>TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.</p>Formule :C25H22N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :466.49(R)-MLT-985
CAS :<p>(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.</p>Formule :C17H15Cl2N9O2Couleur et forme :SolidMasse moléculaire :448.27COX-2-IN-18
CAS :<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Formule :C18H19N3O3S2Couleur et forme :SolidMasse moléculaire :389.49MD13
<p>MD13 is a macrophage migration inhibitor (MIF) oriented PROTAC (Ki value: 71 nM). MD13 can be used to study cancer.</p>Couleur et forme :LiquidSMA-12b
CAS :<p>SMA-12b is an analog of the immunomodulatory parasite product ES-62 that has immunomodulatory activity and can be used in the study of rheumatoid arthritis.</p>Formule :C13H22INO2SDegré de pureté :98.52% - 99.16%Couleur et forme :SolidMasse moléculaire :383.29Sulfo-ara-F-NMN
CAS :<p>Sulfo-ara-F-NMN: cell-permeable, NMN analogue, activates SARM1, inhibits CD38 (IC50 ~10μM), induces cADPR, NAD loss, non-apoptotic death.</p>Formule :C11H14FN2O6PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.28Mercaptoethylguanidine (MEG) (dihydrobromide)
CAS :<p>MEG dihydrobromide inhibits inducible nitric oxide synthase and scavenges peroxynitrite, potentially aiding in inflammatory bowel disease studies.</p>Formule :C3H11Br2N3SCouleur et forme :SolidMasse moléculaire :281.01AL-8417
CAS :<p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>Formule :C29H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.58IRAK inhibitor 4
CAS :<p>IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.</p>Formule :C33H35F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :620.66L-NIL hydrochloride
CAS :<p>selective inhibitor of inducible nitric oxide synthase</p>Formule :C8H18ClN3O2Degré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :223.7IRAK4-IN-16
CAS :<p>IRAK4-IN-16 inhibits IRAK4 at 2.5nM; cytotoxic to OCI-LY10, TMD8, Ramos, HT cells with IC50s of 0.2, 0.2, 0.6, 2.7μM.</p>Formule :C17H20F2N8OCouleur et forme :SolidMasse moléculaire :390.39CD73-IN-8
CAS :<p>CD73-IN-8 blocks CD73, hindering adenosine production that supports tumor growth, flagged as compound 57 in WO2022052886A1.</p>Formule :C17H13ClN4O2Couleur et forme :SolidMasse moléculaire :340.76STING Agonist 12b
CAS :<p>STING agonist 12b activates human/mouse STING, binds with Kd 26.4 μM, prompts interferon, and induces TNF-a, IL-6, IP-10, IL-1b in THP-1 cells.</p>Formule :C16H15NO2Couleur et forme :SolidMasse moléculaire :253.3GSK319347A
CAS :<p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>Formule :C22H19N3O5S2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :469.53Cyclic-di-GMP
CAS :<p>Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species</p>Formule :C20H24N10O14P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :690.41AMT hydrochloride
CAS :<p>AMT hydrochloride is an iNOS inhibitor.</p>Formule :C5H11ClN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :166.67Mivotilate
CAS :<p>Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.</p>Formule :C12H14N2O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.45AR-C102222 hydrochloride
CAS :<p>AR-C102222 hydrochloride: oral iNOS inhibitor, selective, IC50=37 nM, with anti-inflammatory and pain relief effects.</p>Formule :C19H17ClF2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.83NED-3238
CAS :<p>NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).</p>Formule :C17H28BN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.23Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formule :C29H34N2O15Couleur et forme :SolidMasse moléculaire :650.58MLT-747
CAS :<p>MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).</p>Formule :C20H21Cl2N7O3Couleur et forme :SolidMasse moléculaire :478.33COX-2-IN-11
CAS :<p>COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].</p>Formule :C12H12OS3Couleur et forme :SolidMasse moléculaire :268.42Carpro-AM1
CAS :<p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>Formule :C21H18ClN3OCouleur et forme :SolidMasse moléculaire :363.84ASP-6537
CAS :<p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>Formule :C17H17N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :311.34CU-32
CAS :<p>CU-32 is a cGAS inhibitor with IC50=0.45 μM, blocks DNA-stimulated IFN-β production, and is selective over RIG-I-MAVS and TLRs pathways.</p>Formule :C11H10IN5O2Couleur et forme :SolidMasse moléculaire :371.13PD 127443
CAS :<p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>Formule :C20H28N2OCouleur et forme :SolidMasse moléculaire :312.45TFC-007
CAS :<p>TFC-007 is an H-PGDS inhibitor, reducing inflammation, useful for studying guinea pig allergic rhinitis induced by cedar pollen.</p>Formule :C27H29N5O4Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :487.55Vidarabine phosphate
CAS :<p>Vidarabine phosphate is an adenosine monophosphate analog.</p>Formule :C10H14N5O7PDegré de pureté :99.75%Couleur et forme :White Crystalline PowderMasse moléculaire :347.22Safrole oxide
CAS :<p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>Formule :C10H10O3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :178.18MIF degrader MD13
CAS :<p>MD13, a MIF-degrading PROTAC, disrupts vital protein interactions in cancer and inflammation, showing promise as a therapeutic research tool.</p>Formule :C35H35N5O8Couleur et forme :SolidMasse moléculaire :653.686,2',4'-Trimethoxyflavone
CAS :<p>The compound is an Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). It also has no short term agonist activity and no species or promoter dependence.</p>Formule :C18H16O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.32Naphazoline
CAS :<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Formule :C14H14N2Degré de pureté :99.79%Couleur et forme :White Crystalline Powder SolidMasse moléculaire :210.271-Dehydro-[10]-gingerdione
CAS :<p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>Formule :C21H30O4Couleur et forme :SolidMasse moléculaire :346.46L-NMMA acetate
CAS :<p>L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.</p>Formule :C9H20N4O4Degré de pureté :99.72% - 99.8%Couleur et forme :White To Off-White SolidMasse moléculaire :248.28IKK2-IN-4
CAS :<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Formule :C12H11N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :261.3IL-17A modulator-3
CAS :<p>IL-17A modulator-3 inhibits IL-17A/A, IC50 <10 μM, for inflammation, cancer, autoimmune research.</p>Formule :C34H50FN7O4Couleur et forme :SolidMasse moléculaire :639.8APY0201
CAS :<p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>Formule :C23H23N7ODegré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :413.48TYT-1
CAS :<p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>Formule :C21H17N3O2S3Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :439.57Naproxen etemesil
CAS :<p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>Formule :C17H20O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.4NLRP3-IN-25
CAS :<p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>Formule :C17H19F3N4O5SCouleur et forme :SolidMasse moléculaire :448.42L 669083
CAS :<p>L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.</p>Formule :C29H29IN4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.54LY 150310
CAS :<p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>Formule :C13H14N2Couleur et forme :SolidMasse moléculaire :198.26Fagaramide
CAS :<p>Fagaramide possesses Antiplasmodial activity.</p>Formule :C14H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.29NCX-6560
CAS :<p>NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.</p>Formule :C37H42FN3O8Couleur et forme :SolidMasse moléculaire :675.74ZXX2-77
CAS :<p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>Formule :C13H13ClN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.77Tiazotic acid
CAS :<p>Tiazotic acid is an agent with the activity of antioxidant.</p>Formule :C5H7N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :173.19L 748780
CAS :<p>L 748780 is a selective inducible COX-2 inhibitor.</p>Formule :C19H14Cl3NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.68Oxyfenamate
CAS :<p>Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.</p>Formule :C11H15NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.24Anisodine hydrobromide
CAS :<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Formule :C17H22BrNO5Couleur et forme :White Crystals Or Crystalline PowderMasse moléculaire :400.27FR20
CAS :<p>FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.</p>Formule :C31H25Cl2N3O2Couleur et forme :SolidMasse moléculaire :542.46LC-R 505
CAS :<p>LC-R 505 is an anti-inflammatory.</p>Formule :C20H26N2O5SCouleur et forme :SolidMasse moléculaire :406.5NCX1022
CAS :<p>NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.</p>Formule :C29H35NO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.59GSK223
CAS :<p>GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.</p>Formule :C21H18FN3O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.51MIP-1072
CAS :<p>MIP-1072 is the prostate-specific membrane antigen inhibitor.</p>Formule :C19H26IN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.33hDDAH-1-IN-1
CAS :<p>hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>Formule :C8H20N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :188.27TL8-506
CAS :<p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>Formule :C20H17N3O2Degré de pureté :95% - 99.97%Couleur et forme :SolidMasse moléculaire :331.37BPK-29
CAS :<p>BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.</p>Formule :C26H32ClN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4703-OH-Kynurenamine dihydroiodide
CAS :<p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>Formule :C9H14I2N2O2Couleur et forme :SolidMasse moléculaire :436.03UPF-648 sodium salt
CAS :<p>UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).</p>Formule :C11H8Cl2NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.07AHR-6293
CAS :<p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>Formule :C15H12ClNO3Couleur et forme :SolidMasse moléculaire :289.71QM385
CAS :<p>QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).</p>Formule :C17H18F3N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.37Loxoprofenol-SRS tromethamine
CAS :<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Formule :C19H31NO6Couleur et forme :SolidMasse moléculaire :369.45Avenanthramide-C methyl ester
CAS :<p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>Formule :C17H15NO6Couleur et forme :SolidMasse moléculaire :329.3BSP16
CAS :<p>BSP16: potent, oral STING agonist; boosts interferon genes; promising for cancer research.</p>Formule :C16H18O5SeCouleur et forme :SolidMasse moléculaire :369.27NPD926
CAS :<p>NPD926 is an inducer of cancel cell death.</p>Formule :C29H35ClN2O2Couleur et forme :SolidMasse moléculaire :479.05ML388
CAS :<p>ML388 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formule :C20H24N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.43TML-6
CAS :<p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>Formule :C30H37NO7Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :523.62MIF-IN-4 hydrochloride
CAS :<p>MIF-IN-4 hydrochloride inhibits MIF, a cytokine; has pIC50 of 5.01-6, affecting macrophage movement.</p>Formule :C26H29ClN6O2Couleur et forme :SolidMasse moléculaire :493.01546C88
CAS :<p>546C88 is an inhibitor of nitric oxide synthase.</p>Formule :C7H17ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.69AXC-715 trihydrochloride
CAS :<p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>Formule :C18H28Cl3N5Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :420.81COX-2-IN-17
CAS :<p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>Formule :C20H23ClN6O2Couleur et forme :SolidMasse moléculaire :414.89Etoricoxib HCl
CAS :<p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>Formule :C18H16Cl2N2O2SCouleur et forme :SolidMasse moléculaire :395.30ABD-350
CAS :<p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>Formule :C19H22F2O2Couleur et forme :SolidMasse moléculaire :320.37L-Nabe
CAS :<p>L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor.</p>Formule :C13H19N5O4Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :309.32(R)-MALT1-IN-3
CAS :<p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>Formule :C21H19F3N8O2Couleur et forme :SolidMasse moléculaire :472.42AI-3
CAS :<p>Nrf2/Keap1 and Keap1/Cul3 interaction inhibitor</p>Formule :C11H13ClO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.8Phox-I1
CAS :<p>Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.</p>Formule :C23H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.41Avanafil dibesylate
CAS :<p>Avanafil dibesylate is a PDE5 inhibitor.</p>Formule :C35H38ClN7O9S2Couleur et forme :SolidMasse moléculaire :800.3K-80001
CAS :<p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>Formule :C20H17FO2Couleur et forme :SolidMasse moléculaire :308.35IMD-ferulic
<p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>Formule :C36H41N7O4Couleur et forme :SolidMasse moléculaire :635.76NCX 466
CAS :<p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>Formule :C20H24N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.41hDDAH-1-IN-1 TFA
CAS :<p>hDDAH-1-IN-1 TFA is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>Formule :C12H22F6N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.32MIF-IN-5
CAS :<p>MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.</p>Formule :C18H14FN5O2Couleur et forme :SolidMasse moléculaire :351.33COX-2-IN-26
CAS :<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Formule :C23H21N7OS3Couleur et forme :SolidMasse moléculaire :507.65AZD5718
CAS :<p>AZD5718: potent FLAP inhibitor (IC50=2.0 nM), treats Coronary Artery Disease, >90% leukotriene suppression, safe in animal studies, in phase 2a trial.</p>Formule :C29H34N6O4Couleur et forme :SolidMasse moléculaire :530.62CYPMPO
CAS :<p>CYPMPO traps hydroxyl/superoxide radicals; decays in UV/H2O2 (15min) & hypoxanthine/xanthine (51min); outperforms DEPMPO in stability & shelf-life.</p>Formule :C10H18NO4PCouleur et forme :SolidMasse moléculaire :247.23MHY884
CAS :<p>MHY884 inhibits tyrosinase and UVB-triggered NF-κB activation by reducing oxidative stress.</p>Formule :C15H14ClNO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.79Interleukin 1β
CAS :<p>Interleukin 1beta is a bioactive chemical.</p>Formule :C15H28N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.41IACS-8803
CAS :<p>IACS-8803 is a potent cyclic dinucleotide STING agonist that exhibits strong systemic antitumor efficacy.</p>Formule :C20H23FN10O9P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :692.53Heme Oxygenase-1-IN-1 hydrochloride
CAS :<p>HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).</p>Formule :C13H16BrClN2Couleur et forme :SolidMasse moléculaire :315.64MIF-IN-6
CAS :<p>MIF-IN-6 is a potent MIF inhibitor with IC50 1.4 μM, Ki 0.96 μM, and hinders A549 cell growth.</p>Formule :C18H13ClFN5O2Couleur et forme :SolidMasse moléculaire :385.78PC407-ws
CAS :<p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>Formule :C24H18F3N3Na2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :563.46Isocyclosporin A
CAS :<p>Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.</p>Formule :C62H111N11O12Couleur et forme :SolidMasse moléculaire :1202.61ND-2110
CAS :<p>ND-2110, a selective interleukin-1 receptor-associated kinase 4 inhibitors, is used for the treatment of autoimmune disorders and lymphoid malignancy.</p>Formule :C21H28N4O3SCouleur et forme :SolidMasse moléculaire :416.54COX/5-LOX-IN-1
CAS :<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Formule :C18H30O3Couleur et forme :SolidMasse moléculaire :294.43WIN 54954
CAS :<p>WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.</p>Formule :C18H20Cl2N2O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :383.27NOD2 antagonist 1
CAS :<p>NOD2 antagonist 1 (compound 32): Selective, effective (IC50: 5.23μM), blocks MDP-induced IL-8 in THP-1, IL-6/IL-10/TNF-α in PBMCs.</p>Formule :C26H26N4O3SCouleur et forme :SolidMasse moléculaire :474.57Propoxur
CAS :<p>Propoxur: an insecticide causing temporary cholinergic effects in humans; chronic exposure leads to health issues; carcinogenicity unclassified by EPA.</p>Formule :C11H15NO3Degré de pureté :99.84% - 99.87%Couleur et forme :Minute Crystals (Niosh 2016)Masse moléculaire :209.24Pifoxime
CAS :<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Formule :C15H20N2O3Couleur et forme :SolidMasse moléculaire :276.33COX-2/5-LOX-IN-3
CAS :<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Formule :C17H16ClN3O2SCouleur et forme :SolidMasse moléculaire :361.85Indolokine A5
CAS :<p>Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist .</p>Formule :C13H8N2O3SCouleur et forme :SolidMasse moléculaire :272.28Isonixin
CAS :<p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>Formule :C14H14N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.27AR-C 102222
CAS :<p>AR-C 102222 is an iNOS inhibitor.</p>Formule :C19H16F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.37Bifenazate
CAS :<p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>Formule :C17H20N2O3Degré de pureté :99.62%Couleur et forme :Solid CrystallineMasse moléculaire :300.35Simvastatin acid calcium hydrate
CAS :<p>Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.</p>Formule :C25H40O6Couleur et forme :SolidMasse moléculaire :436.28249Tenosal
CAS :<p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>Formule :C12H8O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.25Anti-inflammatory agent 1
CAS :<p>Anti-inflammatory agent 1 is an anti-inflammatory compound.</p>Formule :C17H16O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.37MK-28
CAS :<p>MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.</p>Formule :C24H20N4O2Couleur et forme :SolidMasse moléculaire :396.44B022
CAS :<p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>Formule :C19H16ClN5OSDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :397.88Imeglimin
CAS :<p>Imeglimin: first oral antidiabetic in its class, targets liver, muscle, & pancreatic β-cells for type 2 diabetes.</p>Formule :C6H13N5Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :155.2ER-34122
CAS :<p>ER-34122, a novel orally available dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity.</p>Formule :C27H26ClN3O5Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :507.96YM-53403
CAS :<p>YM-53403: Antiviral that combats both RSV subgroup A/B, treats respiratory infections.</p>Formule :C36H29N3O3SDegré de pureté :98.49% - 98.85%Couleur et forme :SolidMasse moléculaire :583.7CDDO-EA
CAS :<p>CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.</p>Formule :C33H46N2O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :518.73RIG012
CAS :<p>RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.</p>Formule :C23H21NO3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :359.42ABI-1968
CAS :<p>ABI-1968 has antiviral and antitumor activity and can be used to study immune system diseases.</p>Formule :C35H58N5O6PDegré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :675.839Totrombopag
CAS :<p>Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.</p>Formule :C25H22N8O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :466.49DDG-39
CAS :<p>DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture.</p>Formule :C9H12FN3O3Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :229.21SC-75416
CAS :<p>SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.</p>Formule :C15H14ClF3O3Degré de pureté :98.67% - 98.67%Couleur et forme :SolidMasse moléculaire :334.72NFATc1-IN-1
CAS :<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Formule :C13H8F2INO2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :375.11Selnoflast
CAS :<p>Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of coronary arteries and ulcerative colitis.</p>Formule :C20H29N3O3SDegré de pureté :98.54% - 99.66%Couleur et forme :SolidMasse moléculaire :391.53NLRP3/AIM2-IN-2
CAS :<p>NLRP3/AIM2-IN-2, potent species-specific NLRP3 and AIM2 inflammasome pyroptosis inhibitor; IC50 = 0.2392 ± 0.0233 μM.</p>Formule :C15H15NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :257.28LMT-28
CAS :<p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>Formule :C17H29NO4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :311.42Rabeximod
CAS :<p>Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.</p>Formule :C22H24ClN5ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :409.91NLRP3-IN-10
CAS :<p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>Formule :C17H14BrFO3Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :365.19Desmosterol
CAS :<p>Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation .</p>Formule :C27H44ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :384.64IQP-0528
CAS :<p>IQP-0528: Potent NNRTI, blocks HIV entry, microbicidal gel, EC50: 0.2 nM for HIV-1, 100 nM for HIV-2.</p>Formule :C20H24N2O3Degré de pureté :98.36% - >99.99%Couleur et forme :SolidMasse moléculaire :340.42BIT225
CAS :<p>BIT225 is an HIV-1 Vpu inhibitor with antiviral activity that inhibits HIV-1 replication in myeloid dendritic cells.</p>Formule :C16H15N5ODegré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :293.32FK-330
CAS :<p>FK-330 (FR-260330) is a novel nitric oxide synthase inhibitor that prevents ischemia and reperfusion injury in rat liver transplantation.</p>Formule :C29H28ClF3N6O4Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :617.02R 61837
CAS :<p>R 61837 is a novel rhinovirus inhibitor, a substituted phenylpyridazinamine, with antiviral activity.</p>Formule :C16H20N4ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :284.36IL-4-inhibitor-1
CAS :<p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>Formule :C18H12FN3O2Degré de pureté :98.78% - 99.53%Couleur et forme :SolidMasse moléculaire :321.31BN-82451 2HCl
CAS :<p>BN-82451, a cyclooxygenase inhibitor, is used potentially for the treatment of Huntington’s disease.</p>Formule :C18H28Cl2N2OSDegré de pureté :99.84% - >99.99%Couleur et forme :SolidMasse moléculaire :391.4F092
CAS :<p>F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.</p>Formule :C20H17N5O2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :359.38TLR7/8-IN-1
CAS :<p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>Formule :C29H40N8O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :532.68NDT 9513727
CAS :<p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>Formule :C36H35N3O4Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :573.68LDC7559
CAS :<p>LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.</p>Formule :C20H19N3O3Degré de pureté :99.8%Couleur et forme :SoildMasse moléculaire :349.38SM360320
CAS :<p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>Formule :C15H17N5O3Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :315.33IL-2-IN-1
CAS :<p>IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.</p>Formule :C17H12F6N4O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :418.29CMX-521
CAS :<p>CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.</p>Formule :C13H17N5O5Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.3Complement C5-IN-1
CAS :<p>Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).</p>Formule :C24H32N2O6Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :444.52Zabedosertib
CAS :<p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>Formule :C20H21F3N4O4SDegré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :470.47NFAT Transcription Factor Regulator-1
CAS :<p>NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).</p>Formule :C17H10F6N4O2Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :416.28IRAK4-IN-20
CAS :<p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>Formule :C22H25F3N4O3Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :450.45BBIQ
CAS :<p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1</p>Formule :C21H22N4Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :330.43BRD56491
CAS :<p>BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.</p>Formule :C20H14O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :286.32FEN1-IN-3
CAS :<p>FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .</p>Formule :C15H12N2O4Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :284.27EIDD-2749
CAS :<p>EIDD-2749 (4'-Fluorouridine), an oral drug, inhibits RdRp, halts RSV/SARS-CoV-2 replication, and fights HCV/LCMV.</p>Formule :C9H11FN2O6Degré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :262.19HS271
CAS :<p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>Formule :C21H24F3N5O2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :435.44JC124
CAS :<p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>Formule :C17H19ClN2O4SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :382.86Antiviral agent 17
CAS :<p>Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.</p>Formule :C11H14N4O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :266.25Zharp2-1
CAS :<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Formule :C19H18N3O2PSDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :383.4Rufigallol
CAS :<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Formule :C14H8O8Degré de pureté :98.92% - 99.27%Couleur et forme :SolidMasse moléculaire :304.21T6167923
CAS :<p>T6167923 inhibits MyD88 signaling, binds TIR domain, blocks dimer formation, lowers SEAP activity, and has anti-inflammatory IC50s ~2.7 μM.</p>Formule :C17H20BrN3O3S2Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :458.39Azalanstat
CAS :<p>Azalanstat (RS 21607) is a mammalian lanosterol 14-alpha-demethylase inhibitor with hypocholesterolemic activity.</p>Formule :C22H24ClN3O2SDegré de pureté :99.41% - 99.85%Couleur et forme :SolidMasse moléculaire :429.96M62812
CAS :<p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>Formule :C13H13Cl2N3OSDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :330.23Dersalazine
CAS :<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Formule :C35H32N6O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :600.67NO-prednisolone
CAS :<p>NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.</p>Formule :C29H33NO9Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :539.57ABT-963
CAS :<p>ABT-963: COX-2 inhibitor for osteoarthritis/pain with high selectivity, potency, and gastric safety.</p>Formule :C22H22F2N2O5SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :464.48RIPK1-IN-9
CAS :<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Formule :C26H25FN6O2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :472.51AHR antagonist 2
CAS :<p>AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.</p>Formule :C20H17F3N4O3Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :418.37C3a Receptor Agonist
CAS :<p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>Formule :C27H35N3O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :433.59SP-100030
CAS :<p>SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.</p>Formule :C14H5ClF9N3ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :437.65Ezurpimtrostat hydrochloride
CAS :<p>Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.</p>Formule :C25H32Cl2N4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :459.45Letosteine
CAS :<p>Letosteine, an oral expectorant, treats acute/chronic respiratory diseases by dissolving mucus and reducing inflammation.</p>Formule :C10H17NO4S2Degré de pureté :96.03%Couleur et forme :SolidMasse moléculaire :279.38Thiodigalactoside
CAS :<p>Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM</p>Formule :C12H22O10SDegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :358.36Biofor 389
CAS :<p>Biofor 389 (BF389) has anti-inflammatory activity and can be used to study arthritis.</p>Formule :C20H29NO3Degré de pureté :98.84% - 99.97%Couleur et forme :SolidMasse moléculaire :331.45h-NTPDase8-IN-1
CAS :<p>h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8, which can be used to study diseases caused by aberrant h-NTPDase expression.</p>Formule :C10H10ClNO4SDegré de pureté :98.78% - 99.59%Couleur et forme :SolidMasse moléculaire :275.71Rociclovir
CAS :<p>Rociclovir has antiviral activity and is used to treat viral infections.</p>Formule :C15H25N5O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :323.39EG00229
CAS :<p>EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.</p>Formule :C19H20F3N7O7S3Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :611.6GSK2983559 free acid
CAS :<p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>Formule :C21H23N4O7PS2Degré de pureté :97.8700% - 98.61%Couleur et forme :SolidMasse moléculaire :538.53Phox-I2
CAS :<p>Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.</p>Formule :C18H15N3O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :337.33Resiniferatoxin
CAS :<p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>Formule :C37H40O9Degré de pureté :93.08% - 99.34%Couleur et forme :SolidMasse moléculaire :628.71CPS-11
CAS :<p>CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.</p>Formule :C14H12N2O5Degré de pureté :99.8% - 99.98%Couleur et forme :SolidMasse moléculaire :288.26Cindunistat
CAS :<p>Cindunistat (free base) is an orally available selective iNOS inhibitor for the study of arthritis.</p>Formule :C8H17N3O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :219.3Sonlicromanol hydrochloride
CAS :<p>Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator used in the treatment of mitochondrial diseases.</p>Formule :C19H29ClN2O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :368.9CT-2584
CAS :<p>CT-2584: angiogenesis & lysophosphatidic acid transferase inhibitor; alters phospholipid synthesis, increasing PI in tumor cells.</p>Formule :C30H55N5O3Degré de pureté :97.68% - 99.77%Couleur et forme :SolidMasse moléculaire :533.79CPG-52364
CAS :<p>CPG-52364 is a small molecule compound that interacts between an endosomal TLR and its ligand and is a candidate for the treatment of psoriasis.</p>Formule :C27H36N6O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :492.61APX-115
CAS :<p>APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).</p>Formule :C17H18ClN3ODegré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :315.8AT791
CAS :<p>AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.</p>Formule :C23H31N3O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :397.51Epetirimod
CAS :<p>Epetirimod (S-30563) is a small molecule immunomodulator with antitumor and anti-infective activity for the study of papillomavirus infections.</p>Formule :C13H15N5Degré de pureté :99.08% - 99.53%Couleur et forme :SolidMasse moléculaire :241.29
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