Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(270 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(97 produits)
- Lipides(59 produits)
- Lipoxygénase(125 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(164 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8626 produits trouvés pour "Métabolisme"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
UGT1A1-IN-1
CAS :<p>UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].</p>Formule :C22H19NO3Couleur et forme :SolidMasse moléculaire :345.39Porphobilinogen
CAS :<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Formule :C10H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.23Alkannin
CAS :<p>Alkannin: potent, tumor-specific PKM2 inhibitor; non-inhibitory to PKM1/PKL; potential anticancer agent.</p>Formule :C16H16O5Couleur et forme :SolidMasse moléculaire :288.37-APB hydrochloride
CAS :<p>7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.</p>Formule :C11H14ClNOCouleur et forme :SolidMasse moléculaire :211.688Carbonic anhydrase inhibitor 10
<p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>Formule :C14H17N5O3SCouleur et forme :SolidMasse moléculaire :335.38PDE4-IN-14
CAS :<p>PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including</p>Formule :C19H20F2N4O3SCouleur et forme :SolidMasse moléculaire :422.4513(R)-HODE
CAS :<p>13(R)-HODE, produced from linoleic acid, inhibits platelet aggregation (IC50=2.7μM) and is found in bovine endothelial cells.</p>Formule :C18H32O3Couleur et forme :SolidMasse moléculaire :296.44Lipoxin A5
CAS :<p>LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.</p>Formule :C20H30O5Couleur et forme :SolidMasse moléculaire :350.45LASSBio-1632
<p>LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.</p>Formule :C18H20N2O6SCouleur et forme :SolidMasse moléculaire :392.43CIT-ALD
CAS :<p>CIT-ALD is an aldehyde intermediate formed during the metabolism of Citalopram. It has potential applications in the research of neurological disorders.</p>Formule :C18H14FNO2Masse moléculaire :295.31Lufironil
CAS :<p>Lufironil (HOE 077) is an inhibitor of prolyl 4-hydroxylase, designed for investigating chronic liver conditions such as alcoholic hepatitis and cirrhosis.</p>Formule :C13H19N3O4Couleur et forme :SolidMasse moléculaire :281.31ATUX-8385
CAS :<p>ATUX-8385 is a potent activator of PP2A. It binds to the PR65 subunit and holds promise for research into cancer and chronic diseases, including Alzheimer's disease and chronic obstructive pulmonary disease (COPD).</p>Formule :C24H20F5N3O4SCouleur et forme :SolidMasse moléculaire :541.49ATX inhibitor 12
<p>Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.</p>Formule :C30H34FN5O2Couleur et forme :SolidMasse moléculaire :515.62Keto lovastatin
CAS :<p>Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.</p>Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.523Monoamine Oxidase B inhibitor 6
CAS :<p>Monoamine OxidaseB inhibitor 6 (Compound BT5) is a highly selective, reversible, and competitive MAO-B inhibitor capable of crossing the blood-brain barrier, with an IC50 of 0.11 μM. It exhibits antioxidant and neuroprotective properties, making it suitable for research into neurodegenerative diseases.</p>Formule :C15H15N3OSCouleur et forme :SolidMasse moléculaire :285.364ALOX15-IN-1
<p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>Formule :C24H31N3O5SCouleur et forme :SolidMasse moléculaire :473.59α-Glucosidase-IN-19
<p>Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.</p>Formule :C31H25NOSCouleur et forme :SolidMasse moléculaire :459.6Desmonomethylpromazine
CAS :<p>Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.</p>Formule :C16H18N2SCouleur et forme :SolidMasse moléculaire :270.39ACLY Inhibitor 7
CAS :<p>ACLY Inhibitor 7 is a potent, selective hACLY inhibitor (IC50<1 nM) for metabolic disease and oncology research.</p>Formule :C21H14ClF2NO6SDegré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :481.85TAK-828F
CAS :<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formule :C28H32FN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.57HSD17B13-IN-40
CAS :HSD17B13-IN-40 (compound 6) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as substrates. This compound is significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formule :C23H14Cl2F3N3O3Masse moléculaire :508.28AChE/BChE-IN-23
<p>AChE/BChE-IN-23 (Compound 6e) is a dual inhibitor of acetylcholinesterase and butyrylcholinesterase, exhibiting IC50 values of 0.91 μM for AChE, 1.19 μM for eqBChE, and 1.01 μM for hBChE. This compound also demonstrates antioxidant properties and inhibits the aggregation of Aβ1-42 and Tau proteins. Moreover, AChE/BChE-IN-23 prevents the activation of microglial cells by inhibiting the release of reactive oxygen species and mitochondrial damage. Additionally, it reduces the levels of the NLRP3 inflammasome in human microglial cells and reverses memory impairment in mice induced by scopolamine.</p>Formule :C19H21N5O3Couleur et forme :SolidMasse moléculaire :367.4MAGL-IN-20
<p>MAGL-IN-20 (compound ±34) is a reversible inhibitor of monoacylglycerol lipase (MAGL). It exhibits significant antiproliferative activity against a range of cancer cell lines, including H460, HT29, CT-26, Huh7, and HCCLM-3.</p>Formule :C23H24N2OCouleur et forme :SolidMasse moléculaire :344.45FXR agonist 9
CAS :<p>FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 µM (maximum efficacy of 75.13%). It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.</p>Formule :C28H30N2O5Couleur et forme :SolidMasse moléculaire :474.55Carbonic anhydrase inhibitor 17
CAS :<p>Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.</p>Formule :C18H15ClN4O3S2Masse moléculaire :434.927PPD-Q
CAS :<p>7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).</p>Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.41Monoamine oxidase/Aromatase-IN-1
<p>Compound 2q: Dual MAO/aromatase inhibitor; IC50: 39 nM (MAO-B), 31 nM (aromatase). Useful in neurological/breast cancer research.</p>Formule :C19H19N3O3SCouleur et forme :SolidMasse moléculaire :369.44PDHK-IN-5
<p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>Formule :C30H31N5O2Couleur et forme :SolidMasse moléculaire :493.6Estradiol 3-glucuronide
CAS :<p>Estradiol 3-glucuronide is an immunogen with antigenic properties. The antiserum induced in rabbits exhibits high affinity and specificity for Estradiol 3-glucuronide. This compound shows promise for use in research involving radioimmunoassay.</p>Formule :C24H32O8Couleur et forme :SolidMasse moléculaire :448.51MD 770222
CAS :<p>MD 770222, the principal plasma O-demethylated metabolite of Cimoxatone, is an orally active selective and reversible inhibitor of MAO A. The potency of MD 770222 is lower than that of Cimoxatone.</p>Formule :C18H16N2O4Couleur et forme :SolidMasse moléculaire :324.33AChE/CA I-IN-1
<p>AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.</p>Formule :C14H19NO6SCouleur et forme :SolidMasse moléculaire :329.37ZMC3
CAS :<p>ZMC3 (NSC328784), a zinc chelator, exhibits properties as a zinc metallochaperone. It shows enhanced sensitivity in cells with the p53-R175H mutation and increases the cellular levels of ROS (reactive oxygen species).</p>Formule :C17H20N6SeCouleur et forme :SolidMasse moléculaire :387.343-Oxochenodeoxycholic acid
CAS :3-Oxochenodeoxycholic acid is an endogenous metabolite detectable in feces and may serve as a diagnostic marker for various diseases, including COVID-19.Formule :C24H38O4Masse moléculaire :390.556Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formule :C21H18N2O4SCouleur et forme :SolidMasse moléculaire :394.44FR 901537
CAS :<p>FR 901537 is a new aromatase inhibitor with antitumor effects.</p>Formule :C23H29N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.62FXIa-IN-9
CAS :<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formule :C23H18Cl2F3N9O2Couleur et forme :SolidMasse moléculaire :580.35L-Sepiapterin
CAS :<p>L-Sepiapterin aids in making BH4, a coenzyme essential for eNOS, enhancing artery function and angiogenesis, while suppressing ovarian cancer cell growth.</p>Formule :C9H11N5O3Couleur et forme :SolidMasse moléculaire :237.22ROR1-IN-1
CAS :<p>ROR1-IN-1 (Compound 19h) is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) with a Ki of 0.10 μM. It inhibits the proliferation of cancer cell lines H1975, A549, and MDA-MB-231, with IC50 values of 0.36 μM, 1.37 μM, and 0.47 μM, respectively. In mice, ROR1-IN-1 demonstrates antitumor efficacy and exhibits favorable pharmacokinetic properties in a rat model.</p>Formule :C33H27N5O3Masse moléculaire :541.60Lp(a)-IN-7
CAS :<p>Lp(a)-IN-7 (example 1) is an inhibitor of lipoprotein (a) [Lp(a)] formation, exhibiting an IC50 of 2.51 nM in media containing apolipoprotein B (apoB) and apolipoprotein (a). This compound is applicable in cardiovascular disease research.</p>Formule :C20H30Cl2N2O4Couleur et forme :SolidMasse moléculaire :433.369IDH1 Inhibitor 1
CAS :<p>Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.</p>Formule :C20H18F4N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.39FAAH/MAGL-IN-2
CAS :<p>FAAH/MAGL-IN-2: potent, reversible, oral FAAH & MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.</p>Formule :C15H13Cl2N3O3SCouleur et forme :SolidMasse moléculaire :386.25DS44470011
CAS :<p>DS44470011 is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) with oral bioavailability. It enhances the release of erythropoietin (EPO) from cells and is utilized in research related to renal anemia.</p>Formule :C21H19N3O4Couleur et forme :SolidMasse moléculaire :377.39BMS-214662 mesylate
CAS :<p>BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.</p>Formule :C26H27N5O5S3Couleur et forme :SolidMasse moléculaire :585.718RO5101576
CAS :<p>RO5101576 is a potent antagonist of LTB4 receptor.</p>Formule :C36H38O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :630.75FXIa-6f
CAS :<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04NTPDase-IN-3
CAS :<p>NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.</p>Formule :C22H24ClN3OS2Couleur et forme :SolidMasse moléculaire :446.03SGK1-IN-3
<p>SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.</p>Formule :C23H20Cl2N6O3SCouleur et forme :SolidMasse moléculaire :531.41Rostratin A
CAS :<p>Rostratin A, a disulfide from Exserohilum rostratum, is cytotoxic to HCT-116 cells with an IC50 of 8.5 μg/mL.</p>Formule :C18H24N2O6S2Couleur et forme :SolidMasse moléculaire :428.52L-Afegostat
CAS :<p>L-Afegostat (5-epi-Isofagomine), an iminosugar, inhibits glycosidase and β-Glucosidase (K i 30 μM), aids in carbohydrate synthesis.</p>Formule :C6H13NO3Couleur et forme :SolidMasse moléculaire :147.17GC-IN-2
CAS :<p>GC-IN-2 (Compound 25) is an effective and selective non-sugar-based glucocerebrosidase inhibitor with an IC50 value of 6.46 μM. It is utilized in research related to Gaucher's disease.</p>Formule :C19H16N2O3SCouleur et forme :SolidMasse moléculaire :352.41FABP1-IN-1
CAS :<p>FABP1-IN-1 (44) is a selective FABP1 inhibitor with an IC50 value of 4.46 μM. It is applicable in research related to alcoholic fatty liver disease.</p>Formule :C30H25NO5Masse moléculaire :479.524-(4-Bromophenyl)-4-hydroxypiperidine
CAS :<p>4-(4-Bromophenyl)-4-hydroxypiperidine (BPHP) is a metabolite of Bromperidol (BRO), produced through the N-dealkylation of BRO.</p>Formule :C11H14BrNOCouleur et forme :SolidMasse moléculaire :256.139FXR agonist 12
CAS :<p>FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.</p>Formule :C26H44O3Couleur et forme :SolidMasse moléculaire :404.626BMS-341400 mesylate
CAS :<p>BMS-341400 mesylate (Compound 6) is an orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 0.3 nM and is useful in the study of erectile dysfunction.</p>Formule :C24H26ClN9O5SCouleur et forme :SolidMasse moléculaire :588.0396-trans-12-epi-Leukotriene B4
CAS :<p>6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47GK420
CAS :<p>GK420 (AVX420) is a potent inhibitor of cytoplasmic phospholipase A2α (cPLA2α), with an XI(50) value of 0.0016. It effectively inhibits the release of arachidonic acid, with an EC50 of 0.09 μM. GK420 plays a significant role in cancer research.</p>Formule :C20H25NO5SCouleur et forme :SolidMasse moléculaire :391.481DLCI-1
CAS :<p>DLCI-1 is a potent and selective oral inhibitor of cytochrome P450 2A6 (CYP2A6), significantly reducing self-administered nicotine doses in both male and female mice.</p>Formule :C12H14N2SCouleur et forme :SolidMasse moléculaire :218.32Anticancer agent 142
CAS :<p>Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].</p>Formule :C13H14BrF2N2O7PS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.262-Amino-5-methyl-5-hexenoic acid
CAS :<p>2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.</p>Formule :C7H13NO2Couleur et forme :SolidMasse moléculaire :143.184JTZ-951 HCl
CAS :<p>JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).</p>Formule :C17H17ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.799-cis-β-Carotene
CAS :<p>9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.</p>Formule :C40H56Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.872,4-Dihydroxybutanoic acid
CAS :<p>2,4-Dihydroxybutanoic acid is typically not found in extracts of normal human urine and is present only in trace amounts in newborns, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.</p>Formule :C4H8O4Couleur et forme :SolidMasse moléculaire :120.10AD013
<p>AD013 is a selective ACE inhibitor and NEP inhibitor with potential anti-hypertensive and cardioprotective benefits.</p>Formule :C24H28N2O5Couleur et forme :SolidMasse moléculaire :424.49SHP2-IN-9
<p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>Formule :C20H20FN3O2SCouleur et forme :SolidMasse moléculaire :385.46NTPDase-IN-1
<p>NTPDase-IN-1 selectively inhibits NTPDases 1, 2, 8 with IC50 of 0.05, 0.23, 0.54 μM. Non-competitive, K m 21 μM, used in cancer, immune, infection research.</p>Formule :C18H25N3OS2Couleur et forme :SolidMasse moléculaire :363.541-Stearoyl-sn-glycerol 3-phosphate sodium
CAS :<p>1-Stearoyl-sn-glycerol 3-phosphate sodium, a biologically active phospholipid, plays a crucial role in regulating cell motility, proliferation, invasion, survival, and the production of growth factors through interactions with G protein-coupled receptors (GPCR). Synthesized during the formation of membrane phospholipids, this compound typically has a low plasma concentration (approximately 100nM) and originates from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its distinctive structure features stearic acid at the sn-1 position and a hydroxyl group at the sn-2 position.</p>Formule :C21H42NaO7PCouleur et forme :SolidMasse moléculaire :460.52Moiramide B
CAS :<p>Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.</p>Formule :C25H31N3O5Degré de pureté :98.53% - 99.90%Couleur et forme :SolidMasse moléculaire :453.53Dual FAAH/sEH-IN-1
CAS :<p>Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.</p>Formule :C25H22ClN3O3S2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :512.04BAY-3827
CAS :<p>BAY-3827 is an AMPK inhibitor with antiproliferative activity and antitumor activity. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.</p>Formule :C27H25FN6ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :468.53JNJ-6204
CAS :<p>JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.</p>Formule :C19H11D6FN6ODegré de pureté :97.42% - 99.87%Couleur et forme :SolidMasse moléculaire :370.41MAO-B-IN-17
CAS :<p>MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.</p>Formule :C17H17F2NO2Degré de pureté :99.41%Couleur et forme :SoildMasse moléculaire :305.32ALOX15-IN-2
CAS :<p>ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.</p>Formule :C23H29N3O4SDegré de pureté :98.10%Couleur et forme :SolidMasse moléculaire :443.56Glycosyltransferase-IN-1
<p>Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.</p>Formule :C19H21N5ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :335.4CP-642931
CAS :<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Formule :C17H25N7ODegré de pureté :99.67% - >99.99%Couleur et forme :SolidMasse moléculaire :343.43JX237
CAS :JX237 is an SLC6A19 inhibitor, a transporter protein that neutralizes amino acid uptake by the liver, and can be used in the study of cardiovascular disease.Formule :C11H15BrN2ODegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :271.15PREP inhibitor-1
CAS :<p>PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.</p>Formule :C22H28N4O2Degré de pureté :98.78%Couleur et forme :SoildMasse moléculaire :380.48WAY-213613 hydrochloride
CAS :<p>WAY-213613 hydrochloride: potent, selective GLT-1/EAAT2 inhibitor (IC50 85 nM); weaker for EAAT1/3; inactive at glutamate receptors; research tool for CNS.</p>Formule :C16H13BrF2N2O4Degré de pureté :99.14% - 99.37%Couleur et forme :SoildMasse moléculaire :415.19Obicetrapib
CAS :<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Formule :C32H31F9N4O5Degré de pureté :99.26% - >99.99%Couleur et forme :SolidMasse moléculaire :722.6Etamicastat hydrochloride
CAS :<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Formule :C14H16ClF2N3OSDegré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :347.81BMS453
CAS :<p>BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.</p>Formule :C27H24O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :380.48BE1218
CAS :<p>BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.</p>Formule :C30H30FNO4S2Degré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :551.69Lapaquistat acetate
CAS :<p>Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.</p>Formule :C33H41ClN2O9Degré de pureté :99.38% - 99.94%Couleur et forme :SolidMasse moléculaire :645.14DRB18
CAS :<p>DRB18 inhibits GLUT proteins, altering glucose metabolism and inducing cancer cell death by G1/S arrest and oxidative stress.</p>Formule :C22H23ClN2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :382.88Aleglitazar
CAS :<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Formule :C24H23NO5SDegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :437.51STK-15
CAS :<p>STK-15 is a candidate for use as a fatty acid binding protein 5 (FABP5) inhibitor.</p>Formule :C34H29NO5Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :531.6FABPs ligand 6
CAS :<p>FABPs ligand 6 (MF6) is an inhibitor of FABP5 and FABP7.</p>Formule :C28H27FN2O3Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :458.524-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS :Formule :C5H5N5ODegré de pureté :>93.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystallineMasse moléculaire :151.13MK-0941
CAS :<p>MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.</p>Formule :C22H28N4O9S2Couleur et forme :SolidMasse moléculaire :556.61TC-F 2
CAS :<p>TC-F 2 is a FAAH inhibitor.</p>Formule :C26H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.51L-690330
CAS :<p>L-690330 inhibits human/bovine inositol monophosphatase; Ki: 0.19-0.42 μM. 10x potency vs. mouse/rat IMPase.</p>Formule :C8H12O8P2Couleur et forme :SolidMasse moléculaire :298.12(S)-GNE-140
CAS :<p>(S)-GNE-140 is the less active enantiomer of GNE-140.</p>Formule :C25H23ClN2O3S2Couleur et forme :SolidMasse moléculaire :499.053-Hydroxyhippuric acid
CAS :<p>3-Hydroxyhippuric acid is an acyl glycine, which are normally minor metabolites of fatty acids.</p>Formule :C9H9NO4Couleur et forme :SolidMasse moléculaire :195.17GNE-140 racemate
CAS :<p>GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.</p>Formule :C25H23ClN2O3S2Couleur et forme :SolidMasse moléculaire :499.044-Hydroxyacetophenone oxime
CAS :<p>4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol), a potent COX-2 and hepatic NAT2 inhibitor used as an antipyretic and analgesic drug.</p>Formule :C8H9NO2Couleur et forme :SolidMasse moléculaire :151.168-Dehydrocholesterol
CAS :<p>8-Dehydrocholesterol is a compound whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome.</p>Formule :C27H44OCouleur et forme :SolidMasse moléculaire :384.648Calcitriol Impurities A
CAS :<p>Calcitriol Impurities A refers to the contaminants found in Calcitriol, the hormonally active metabolite of vitamin D3, which serves to activate the vitamin D receptor.</p>Formule :C27H44O3Couleur et forme :SolidMasse moléculaire :416.643-Methylcrotonylglycine
CAS :<p>3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.</p>Formule :C7H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :157.176-Hydroxybentazon
CAS :<p>6-Hydroxybentazon is a phase I metabolite of bentazon, a herbicide.</p>Formule :C10H12N2O4SCouleur et forme :SolidMasse moléculaire :256.28SMND-309
CAS :<p>SMND-309, a metabolite of salvianolic acid B, exhibits neuroprotective effects in cultured neurons and in rats subjected to permanent middle cerebral artery occlusion.</p>Formule :C18H14O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.302PF-06747711
CAS :<p>PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.</p>Formule :C26H26F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.51
![4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb-webp%2FA2699.webp&w=3840&q=75)
