Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(165 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8628 produits trouvés pour "Métabolisme"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Benserazide
CAS :<p>Benserazide blocks dopa decarboxylase; paired with levodopa for Parkinson's to boost CNS dopamine levels and lower dosage.</p>Formule :C10H15N3O5Couleur et forme :SolidMasse moléculaire :257.24Mevalonic acid
CAS :<p>Mevalonic acid is essential for cell growth and proliferation,Mevalonic acid is a precursor in the mevalonate pathway.</p>Formule :C6H12O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :148.16γ-Methylleucine
CAS :<p>Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) is an auxiliary for copper-catalyzed asymmetric Michael reactions.</p>Formule :C7H15NO2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :145.2Glutamamide
CAS :<p>Glutamamide is an anticancer drug.</p>Formule :C5H11N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :145.16ZSET-845
CAS :<p>ZSET-845 is an enhancer of cognitive which enhances choline acetyltransferase activity in the hippocampus in the rat.</p>Formule :C21H18N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.38Piragliatin
CAS :<p>Piragliatin (RO4389620) activates glucokinase, boosts insulin, and lowers glucose in type 2 diabetes.</p>Formule :C19H20ClN3O4SCouleur et forme :SolidMasse moléculaire :421.9Seviteronel racemate
CAS :Seviteronel racemate is the racemate form of Seviteronel and is a potent inhibitor of CYP17 lyase.Formule :C18H17F4N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.34α-Amylase/α-Glucosidase-IN-1
CAS :<p>α-Amylase/α-Glucosidase-IN-1 (compound 33) is an effective inhibitor of α-amylase/α-glucosidase with IC 50 s of 2.01, 2.09 μM for α-amylase and α-glucosidase,</p>Formule :C11H9N5Couleur et forme :SolidMasse moléculaire :211.22LCL521 dihydrochloride
CAS :<p>LCL521 dihydrochloride is a dual inhibitor of ACDase and ASMase, modulating sphingolipid metabolism with potential in cancer and metabolic research.</p>Formule :C31H54Cl2N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :665.69BNS
CAS :BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.Formule :C18H16N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.46Seviteronel R enantiomer
CAS :<p>Seviteronel R enantiomer (VT-464 R enantiomer) is a Seviteronel isomer produced during the manufacturing process.</p>Formule :C18H17F4N3O3Degré de pureté :97.97% - >99.99%Couleur et forme :SolidMasse moléculaire :399.34ARL-67156 trisodium salt hydrate
CAS :ARL-67156 trisodium salt hydrate is an ecto-ATPase inhibitor that prevents metabolism of P2 purinoceptor agonists.Formule :C15H24Br2N5O12P3Couleur et forme :SolidMasse moléculaire :719.11(Rac)-Etavopivat
CAS :<p>(Rac)-Etavopivat, an oral PKR activator, targets sickle cell disease and haemoglobinopathies.</p>Formule :C22H23N3O6SCouleur et forme :SolidMasse moléculaire :457.5IDO1-IN-16
CAS :<p>IDO1-IN-16 (I-1) is an IDO1 inhibitor that targets holo-IDO1 (IC50: 127 nM).</p>Formule :C25H35BrFN5O2Couleur et forme :SolidMasse moléculaire :536.48CGS 35601
CAS :<p>CGS 35601 is a single molecule inhibitor of triple vasopeptidase.</p>Formule :C23H31N3O4SCouleur et forme :SolidMasse moléculaire :445.57hCAIX/XII-IN-3
CAS :<p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>Formule :C20H13F3N2O4Couleur et forme :SolidMasse moléculaire :402.32Mufemilast
CAS :<p>Mufemilast is an inhibitor of phosphodiesterase 4 (PDE4).</p>Formule :C20H22N2O7S2Couleur et forme :SolidMasse moléculaire :466.53Darexaban glucuronide
CAS :<p>Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.</p>Formule :C33H38N4O10Couleur et forme :SolidMasse moléculaire :650.6811β-HSD1-IN-1
CAS :<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formule :C18H14ClF4N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :399.77GS 389
CAS :<p>GS 389, a tetrahydroisoquinoline, relaxes blood vessels by inhibiting brain PDE and raising aorta cGMP.</p>Formule :C19H23NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.39SAR629
CAS :<p>SAR-629 is an MGL inhibitor or 2-AG degradation inhibitor.</p>Formule :C20H19F2N5OCouleur et forme :SolidMasse moléculaire :383.39Sterculic acid
CAS :<p>Sterculic acid inhibits SCD1 with IC50 of 0.9μM, affecting Δ9D desaturase activity.</p>Formule :C19H34O2Couleur et forme :SolidMasse moléculaire :294.47hCAII-IN-2
CAS :<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Formule :C25H18ClN5O4SCouleur et forme :SolidMasse moléculaire :519.96UKI-1
CAS :<p>UKI-1 is a urokinase-type plasminogen activator system synthetic inhibitor.</p>Formule :C32H47N5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :613.81hCAIX-IN-11
CAS :<p>hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.</p>Formule :C21H15ClN4O3Couleur et forme :SolidMasse moléculaire :406.82Genz-669178
CAS :<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Formule :C17H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.38Eribaxaban
CAS :<p>Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.</p>Formule :C24H22ClFN4O4Degré de pureté :98.99% - 99.13%Couleur et forme :SolidMasse moléculaire :484.91ONO-1603
CAS :<p>ONO-1603, a prolyl endopeptidase inhibitor, is used potentially for the treatment of Alzheimer's disease.</p>Formule :C16H19ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.79IM176OUT05
CAS :IM176OUT05 activates stem cell metabolism with hair regrowth-promoting effects.Formule :C11H17N5Couleur et forme :SolidMasse moléculaire :219.29RP 73163 Racemate
CAS :RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent inhibitor of ACAT, shows cholesterol lowering activity.Formule :C25H28N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.58Teglarinad chloride
CAS :<p>Teglarinad chloride (GMX-1777 chloride) is an inhibitor of NAMPT with antitumor activity that acts by interfering with DNA repair and inhibiting angiogenesis.</p>Formule :C30H43Cl2N5O8Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :672.6CD 2314
CAS :<p>CD2314 is a potent and subtype-selective RARβ receptor agonist with a Kd of 195 nM in S91 melanoma cells [1].</p>Formule :C23H24O2SCouleur et forme :SolidMasse moléculaire :364.5Fodipir
CAS :<p>Fodipir, the active metabolite of mangafodipir, plays a crucial role in the mechanism of mangafodipir-mediated cytoprotection, specifically mitigating cell</p>Formule :C22H32N4O14P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :638.46Carbazomycin B
CAS :<p>Carbazomycin B, a Streptomyces metabolite, combats fungi, bacteria, P. falciparum, C. albicans, and some cancer cells; inhibits 5-LO (IC50=1.5µM).</p>Formule :C15H15NO2Couleur et forme :SolidMasse moléculaire :241.29RORγt inverse agonist 30
CAS :<p>RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist (IC50: 46 nM).</p>Formule :C24H31N3O3SCouleur et forme :SolidMasse moléculaire :441.59Anticancer agent 70
CAS :Compound 21 is a powerful anticancer agent with cytotoxicity against various cancers, causing cell cycle arrest and affecting p53/p21 levels and mitochondria.Formule :C13H9Cl2N3O2SCouleur et forme :SolidMasse moléculaire :342.2Desfluoro-atorvastatin
CAS :<p>Desfluoro-atorvastatin is an impurity of atorvastatin, an oral HMG-CoA reductase inhibitor that lowers blood lipids.</p>Formule :C33H36N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.65KM04416
CAS :<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formule :C12H11NO3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :249.29XEN103
CAS :<p>XEN103 is a potent and selective Stearoyl-CoA Desaturase-1 inhibitor.</p>Formule :C22H23F4N5O2Couleur et forme :SolidMasse moléculaire :465.44PDE1-IN-3
CAS :PDE1-IN-3 is a selective inhibitor of human phosphodiesterase 1 (PDE1).Formule :C18H24N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.41Enpp-1-IN-6
CAS :<p>Enpp-1-IN-6, a potent enpp-1 inhibitor, may aid cancer and infectious disease studies (WO2021203772A1, compound 51).</p>Formule :C22H28N4O5SCouleur et forme :SolidMasse moléculaire :460.55hCAI/II-IN-5
CAS :<p>hCAI/II-IN-5 inhibits human carbonic anhydrase I & II, α-Glycosidase, and AChE, for diabetes, heart failure, Alzheimer's, ulcers, epilepsy research.</p>Formule :C21H18Cl2N8O4S2Couleur et forme :SolidMasse moléculaire :581.45FKGK11
CAS :<p>FKGK11 is a potent inhibitor of GVIA iPLA2.</p>Formule :C13H13F5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :280.23Saterinone hydrochloride
CAS :<p>Saterinone hydrochloride is an inhibitor of phosphodiesterase III (PDE III).</p>Formule :C27H31ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.01Amastatin
CAS :<p>Amastatin is a non-toxic inhibitor of aminopeptidase A and leucine aminopeptidase, and its Ki for aminopeptidase A is 1 μM .</p>Formule :C21H38N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.55TFB-TBOA
CAS :<p>glial glutamate transporter EAAT1 and EAAT2 inhibitor</p>Formule :C19H17F3N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.34JTV-519
CAS :<p>K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) by</p>Formule :C25H33ClN2O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :461.06CDK2-IN-12
CAS :<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Formule :C20H17N9O2SCouleur et forme :SolidMasse moléculaire :447.47LY 56110
CAS :<p>LY 56110 is a novel nonsteroidal aromatase inhibitor.</p>Formule :C17H12Cl2N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.2hCAI/II-IN-1
CAS :<p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>Formule :C18H29N5O3S3Couleur et forme :SolidMasse moléculaire :459.65Fexarine
CAS :<p>Fexarine is a potent, selective agonist of farnesoid X receptor.</p>Formule :C31H31NO5Couleur et forme :SolidMasse moléculaire :497.58IDH-C227
CAS :<p>IDH-C227 is a selective and potent inhibitor of IDH1R132H that exhibits anticancer activity.</p>Formule :C30H31FN4O2Couleur et forme :SolidMasse moléculaire :498.59UK-500001
CAS :<p>UK-500001 is a potent PDE4 inhibitor with robust anti-inflammatory activity.</p>Formule :C26H24F3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.48PDE-9 inhibitor
CAS :<p>PDE-9 inhibitor is used for treatment neurodegenerative diseases.</p>Formule :C22H27N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.48Arcapillin
CAS :<p>Arcapillin, an anticancer agent, induces apoptosis mediated at least in part by the ERS pathway and inhibits hepatoma tumor growth.</p>Formule :C18H16O8Couleur et forme :SolidMasse moléculaire :360.31L-Canaline
CAS :L-Canaline is a nonprotein amino acid with IC50 of 297 nM against malaria, anticancer properties, and blocks ornithine aminotransferase.Formule :C4H10N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :134.13LY367385
CAS :<p>LY367385 is a highly effective and selective mGluR1a antagonist.</p>Formule :C10H11NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.2Semotiadil recemate fumarate
CAS :Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel antagonist of vasoselective Ca2+ channel.Formule :C33H36N2O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.71SHP2 inhibitor LY6
CAS :<p>SHP2 inhibitor LY6 (LY6) is a potent and selective SHP2 inhibitor (IC50: 9.8 μM) that blocks SHP2-mediated cell signaling and proliferation.</p>Formule :C30H27Cl2N3O4Couleur et forme :SolidMasse moléculaire :564.46PKM2 activator 3
CAS :<p>PKM2 activator 3, with 90 nM AC50, enhances PKM2. It has good Caco-2 permeability, stable, and aids cancer research.</p>Formule :C15H11ClF2N2O3SCouleur et forme :SolidMasse moléculaire :372.77(R)-MLN-4760
CAS :<p>(R)-MLN-4760, the R-enantiomer of MLN-4760, functions as an ACE2 inhibitor and exhibits a half maximal inhibitory concentration (IC50) of 8.4 μM, identifying it</p>Formule :C19H23Cl2N3O4Couleur et forme :SolidMasse moléculaire :428.31ATX inhibitor 19
CAS :<p>ATX inhibitor 19 is a potent inhibitor of ATX (IC50: 156 nM).</p>Formule :C28H33ClN6O2SCouleur et forme :SolidMasse moléculaire :553.12TPN729
CAS :<p>TPN729, a PDE5 inhibitor, has an IC50 of 2.28 nM, used to research erectile dysfunction.</p>Formule :C25H36N6O4SCouleur et forme :SolidMasse moléculaire :516.66PKR activator 1
CAS :<p>PKR activator 1 is a potent activator of pyruvate kinase-R (PKR).</p>Formule :C16H14N8OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.47(R)-Bromoenol lactone
CAS :<p>(R)-Bromoenol lactone (BEL) irreversibly inhibits iPLA2γ with 0.6 μM IC50, not affecting iPLA2β unless at 20-30 μM doses.</p>Formule :C16H13BrO2Couleur et forme :SolidMasse moléculaire :317.18LB42908
CAS :<p>LB42908 is a highly potent Ras farnesyltransferase inhibitor(IC(50)=0.9 nM against H-Ras and 2.4 nM against K-Ras) with potential anticancer activity.</p>Formule :C32H31N5O3Couleur et forme :SolidMasse moléculaire :533.62N-Oleoyl Leucine
CAS :<p>N-Oleoyl Leucine (Oleoyl-L-leucine) is an N-fatty acyl amino acid present in plasma.</p>Formule :C24H45NO3Degré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :395.62MEDS433
CAS :<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formule :C20H11F4N3O2Couleur et forme :SolidMasse moléculaire :401.31Loxoprofenol-SRS
CAS :<p>Loxoprofenol-SRS, a potent metabolite of Loxoprofen, is an IV NSAID with enhanced anti-inflammatory and pain relief properties.</p>Formule :C15H20O3Couleur et forme :SolidMasse moléculaire :248.32SR1555 HCl
CAS :<p>SR1555: A selective RORγ inverse agonist, hinders TH17 cells, key in autoimmune diseases like RA and MS.</p>Formule :C22H22F6N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.41Asp-AMS
CAS :Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.Formule :C14H19N7O9SCouleur et forme :SolidMasse moléculaire :461.41DNJNAc
CAS :<p>DNJNAc (2-Acetamido-1,2-dideoxynojirimycin) is a potent β-hexosaminidase inhibitor, reducing cartilage matrix degradation, relevant in glycoconjugate studies.</p>Formule :C8H16N2O4Degré de pureté :98.65% - 99.37%Couleur et forme :SolidMasse moléculaire :204.22PDE10-IN-5
CAS :<p>PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor that can be used to study certain central nervous system disorders.</p>Formule :C26H19F3N4OCouleur et forme :SolidMasse moléculaire :460.45Quetiapine sulfoxide
CAS :<p>Quetiapine sulfoxide: Main metabolite of Quetiapine, a 5-HT agonist & dopamine antagonist antipsychotic.</p>Formule :C21H25N3O3SDegré de pureté :98%Couleur et forme :Pale Yellow SolidMasse moléculaire :399.51TPN729MA
CAS :<p>TPN729MA, a potent PDE5 inhibitor, IC50: 2.28 nM, targets erectile dysfunction research.</p>Formule :C29H40N6O8SCouleur et forme :SolidMasse moléculaire :632.73GlcN-6-P Synthase-IN-1
CAS :<p>'GlcN-6-P Synthase-IN-1, IC50 3.47 μM, inhibits GlcN-6-P synthase & CYP3A4. Has antimicrobial activity and CNS penetration.'</p>Formule :C20H21N7SCouleur et forme :SolidMasse moléculaire :391.49Phortress free base
CAS :<p>Phortress free base is a P450 CYP1A1-activated antitumor prodrug with antitumor activity.</p>Formule :C20H23FN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.49PF 4800567 hydrochloride
CAS :<p>casein kinase 1ε inhibitor</p>Formule :C17H19Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.27hDHODH-IN-11
CAS :<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formule :C24H23N3O3Couleur et forme :SolidMasse moléculaire :401.46Nampt activator-3
CAS :<p>NAMPT activator-3: a NAT derivative, EC50 of 2.6 μM, KD 132 nM, protects cells, prevents FK866 toxicity, and is neuroprotective in CIPN mice.</p>Formule :C19H20N2O3Couleur et forme :SolidMasse moléculaire :324.37LEI-106
CAS :<p>LEI-106 is an effective dual inhibitor of DAGL-α and ABHD6, with Ki values of 0.7 and 0.8 μM respectively, for obesity and metabolic syndrome research.</p>Formule :C26H27NO6SCouleur et forme :SolidMasse moléculaire :481.56Phenylthiazolylthiourea
CAS :<p>Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.</p>Formule :C10H9N3S2Couleur et forme :SolidMasse moléculaire :235.3314-dehydro Zymostenol
CAS :<p>14-dehydro Zymostenol, a cholesterol precursor, boosts MBP+ oligodendrocytes from precursors at 5.8-17 μM.</p>Formule :C27H44OCouleur et forme :SolidMasse moléculaire :384.64Afegostat
CAS :<p>Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.</p>Formule :C6H13NO3Degré de pureté :98%Couleur et forme :Yellow Low-Melting SolidMasse moléculaire :147.17TAK 21d
CAS :<p>Potent FAAH inhibitor</p>Formule :C19H17F2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.38PF 04671536 hydrochloride
CAS :<p>Potent PDE8B/8A inhibitor; IC50: PDE8B-1.3nM, PDE8A-1.9nM; selective over other PDEs; enhances insulin secretion; orally bioavailable.</p>Formule :C14H19ClN8OSCouleur et forme :SolidMasse moléculaire :382.87hCAI/II-IN-2
CAS :<p>hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.</p>Formule :C12H12N4O5S2Couleur et forme :SolidMasse moléculaire :356.38103D5R
CAS :<p>103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.</p>Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4KT185
CAS :KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells).Formule :C32H33N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.64IDO-IN-4
CAS :<p>IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.</p>Formule :C26H35N3O3Couleur et forme :SolidMasse moléculaire :437.57Ambuphylline
CAS :<p>Ambuphylline (Bufylline) is a theophylline derivative and bronchodilator for asthma and lung disease research.</p>Formule :C11H19N5O3Couleur et forme :SolidMasse moléculaire :269.305Talarozole (R enantiomer)
CAS :<p>Talarozole R enantiomer is a potent and selective inhibitor of cytochrome P450 26-mediated breakdown of endogenous all-trans retinoic acid.</p>Formule :C21H23N5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.51IQA
CAS :<p>IQA is a casein kinase 2 (CK2) inhibitor.</p>Formule :C17H12N2O3Couleur et forme :SolidMasse moléculaire :292.2911β-HSD1-IN-10
CAS :<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formule :C16H10F3NO2Couleur et forme :SolidMasse moléculaire :305.25Rev 5975
CAS :<p>Rev 5975 is a non-sulfhydryl ACE-inhibitor.</p>Formule :C24H30N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.51SCD1 Inhibitor
CAS :<p>SCD1 Inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.</p>Formule :C21H20F3N3O3Couleur et forme :SolidMasse moléculaire :419.4RORγt inverse agonist 28
CAS :<p>RORγt inverse agonist 28 is a potent RORγt inverse agonist.</p>Formule :C23H18Cl2F3NO5SCouleur et forme :SolidMasse moléculaire :548.36SHP844
CAS :<p>SHP844: SHP2 inhibitor, IC50 18.9 µM, affects cell growth/survival by regulating tyrosine phosphorylation.</p>Formule :C29H24ClN5O6Couleur et forme :SolidMasse moléculaire :573.98hCAIX-IN-10
CAS :<p>"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."</p>Formule :C28H21N3O3SCouleur et forme :SolidMasse moléculaire :479.55FR-221647
CAS :<p>FR-221647: non-nucleoside adenosine deaminase blocker, moderate efficacy, better pharmacokinetics than EHNA/Pentostatin.</p>Formule :C14H17N3O2Couleur et forme :SolidMasse moléculaire :259.3CAY10761
CAS :<p>CAY10761 inhibits ENPP1 (IC50: 467 μM human, 429 μM snake), mushroom tyrosinase (Ki: 1.9 μM), and urease from different sources (IC50: 0.093-<0.125 mM).</p>Formule :C7H8N4O2S2Couleur et forme :SolidMasse moléculaire :244.29AVX-001
CAS :<p>AVX-001, a cytosolic phospholipase A2 (cPLA2) inhibitor, is used potentially for the treatment of psoriasis.</p>Formule :C21H29F3OSCouleur et forme :SolidMasse moléculaire :386.51ONO-6126
CAS :<p>ONO-6126 has anti-inflammatory activity and can inhibit Phosphodiesterase and PDE4 in the treatment of respiratory diseases.</p>Formule :C20H27N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.45Sp-cAMPS
CAS :<p>Rp-cAMPS TEA salt is a cAMP-dependent protein kinase (PKA) activator.</p>Formule :C10H12N5O5PSCouleur et forme :SolidMasse moléculaire :345.27hCAI/II-IN-3
CAS :<p>"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."</p>Formule :C16H18N4O4S2Couleur et forme :SolidMasse moléculaire :394.47IHMT-PI3Kδ-372
CAS :<p>IHMT-PI3Kδ-372 is a selective inhibitor of PI3Kδ with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.</p>Formule :C26H23F2N7O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :503.5Ciraparantag
CAS :<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Formule :C22H48N12O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.7hCAIX/XII-IN-6
<p>hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.</p>Formule :C26H23N3O6S4Couleur et forme :SolidMasse moléculaire :601.74Kurasoin B
CAS :<p>Kurasoin B is an inhibitor of protein farnesyltransferase.</p>Formule :C18H17NO2Couleur et forme :SolidMasse moléculaire :279.33YCT529 free acid
CAS :<p>YCT529 free acid is a potent, selective and orally active RAR-α inhibitor .</p>Formule :C29H25NO3Couleur et forme :SolidMasse moléculaire :435.51JBP485
CAS :<p>JBP485 is an inhibitor of renal transporters OAT1 and OAT3. JBP485 is an antihepatitis agent as a substrate for intestinal PEPT1.</p>Formule :C8H12N2O4Couleur et forme :SolidMasse moléculaire :200.19Anserinone B
CAS :<p>Anserinone B: Antifungal, antibacterial; inhibits S.fimicola (50%), A. furfuraceus (37%); cytotoxic to human tumor cells (GI50=4.4 µg/mL).</p>Formule :C11H14O4Couleur et forme :SolidMasse moléculaire :210.23EDP-305
CAS :<p>EDP-305, an oral FXR agonist, has EC50s of 34 nM/8 nM in CHO/HEK cells, aids in PBC and NASH research with antifibrotic properties.</p>Formule :C36H58N2O5SCouleur et forme :SolidMasse moléculaire :630.92hCAII-IN-1
CAS :<p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>Formule :C21H21BrN6O4SCouleur et forme :SolidMasse moléculaire :533.4Quazodine
CAS :<p>Quazodine is a phosphodiesterase inhibitor.</p>Formule :C12H14N2O2Couleur et forme :SolidMasse moléculaire :218.25Izumerogant
CAS :<p>Izumerogant is an inverse agonist of the retinoid-related orphan receptor-gamma (RORγ).</p>Formule :C22H18ClF4N5O2Couleur et forme :SolidMasse moléculaire :495.86Trandolaprilate hydrate
CAS :<p>Trandolaprilate hydrate, a powerful ACE inhibitor and Trandolapril's main metabolite, is lipophilic with partial c-fos blocking.</p>Formule :C22H32N2O6Couleur et forme :SolidMasse moléculaire :420.5ASP3662
CAS :<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formule :C19H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :424.8TM-1
CAS :<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formule :C26H32N2O6Couleur et forme :SolidMasse moléculaire :468.54Glyoxalase I inhibitor
CAS :<p>Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.</p>Formule :C21H30BrClN4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :613.91Argininic acid
CAS :<p>Argininic acid is an α-amino acid used in the biosynthesis of proteins.</p>Formule :C6H13N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :175.19CAY10762
CAS :<p>CAY10762, a MAGL inhibitor (IC50=34.1 nM), curbs H2O2-induced LDH in Neuro2a cells and boosts 2-AG in mouse brains at 10 mg/kg.</p>Formule :C15H13NOSCouleur et forme :SolidMasse moléculaire :255.33Atreleuton
CAS :<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Formule :C16H15FN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.374,5,6,7-Tetrabromobenzimidazole
CAS :<p>4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1].</p>Formule :C7H2Br4N2Couleur et forme :SolidMasse moléculaire :433.72CYP3A4-IN-3
CAS :<p>CYP3A4-IN-3, a ritonavir analogue, is a potent CYP3A4 inhibitor with an IC50 of 0.075 μM, used as an antiviral and immunosuppressant.</p>Formule :C34H39N3O3SCouleur et forme :SolidMasse moléculaire :569.76Cholesteryl behenate
CAS :<p>Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.</p>Formule :C49H88O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.22CAY10486
CAS :<p>CAY10486 blocks ACAT-1/2, which form cholesterol esters, potentially reducing atherosclerosis; inhibits LDL oxidation. IC50 ~60μM; 28% effect at 3μM.</p>Formule :C19H19NO4Couleur et forme :SolidMasse moléculaire :325.36Valibose
CAS :<p>Valibose, α-glucosidase inhibitor, improves glucose/lipid metabolism, lowers serum BUN/NAG, reduces kidney weight index.</p>Formule :C10H21NO6Couleur et forme :SolidMasse moléculaire :251.28(R)-Irsenontrine
CAS :<p>(R)-Irsenontrine (R-E2027), R-enantiomer, is a potent PDE9 inhibitor, IC50 = 0.041 μM, for neurological disease research.</p>Formule :C22H22N4O3Couleur et forme :SolidMasse moléculaire :390.44OHM1
CAS :<p>OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53</p>Formule :C24H42N6O5Couleur et forme :SolidMasse moléculaire :494.63sEH inhibitor-6
CAS :<p>sEH inhibitor-6 (Compound 3g) is a highly potent soluble epoxide hydrolase (sEH) inhibitor, exhibiting an IC 50 value of 0.5 nM [1].</p>Formule :C21H14ClN3O2Couleur et forme :SolidMasse moléculaire :375.81hCAXII-IN-2
CAS :<p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>Formule :C21H18ClN3O4Couleur et forme :SolidMasse moléculaire :411.84Teglicar
CAS :<p>Teglicar is a selective and reversible liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor.</p>Formule :C22H45N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.61α-Glucosidase-IN-16
CAS :<p>α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM.</p>Formule :C22H18FNSCouleur et forme :SolidMasse moléculaire :347.45AChE/hCA I/II-IN-1
CAS :<p>Compound 6: Potent inhibitor for AChE, Hca I & II with IC50s of 22.21, 60.79, 66.64 nM, useful in glaucoma, Alzheimer's, diabetes research.</p>Formule :C15H13N3SCouleur et forme :SolidMasse moléculaire :267.35Kojibiose
CAS :<p>Kojibiose (Kojibiose) is a disaccharide in honey. Kojibiose is a product of the caramelization of glucose.</p>Formule :C12H22O11Degré de pureté :99.933%Couleur et forme :SolidMasse moléculaire :342.3ALDH3A1-IN-2
CAS :<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formule :C11H14N2O3Couleur et forme :SolidMasse moléculaire :222.244,6-O-Ethylidene-α-D-glucose
CAS :<p>4,6-O-Ethylidene-α-D-glucose (Ethylidene-glucose), a derivative of glucose, serves as a competitive inhibitor for the exofacial binding site of glucose</p>Formule :C8H14O6Couleur et forme :SolidMasse moléculaire :206.19Dapaconazole
CAS :<p>Dapaconazole is used as a drug candidate for antifungals.</p>Formule :C19H15Cl2F3N2OCouleur et forme :SolidMasse moléculaire :415.24SAR127303
CAS :<p>SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.</p>Formule :C16H17ClF6N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.83SDZ-MKS 492
CAS :SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.Formule :C20H27N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.46URB532
CAS :<p>URB532 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor.</p>Formule :C18H21NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.36Fluindione
CAS :<p>Fluindione is a hematologic drug.</p>Formule :C15H9FO2Couleur et forme :SolidMasse moléculaire :240.23Glyoxalase I inhibitor 2
CAS :<p>Glyoxalase I inhibitor 2 (compound 26) blocks GLO1 effectively (IC50: 0.5 μM), promising for depression and anxiety research.</p>Formule :C24H23N3O4SCouleur et forme :SolidMasse moléculaire :449.52Acetaldophosphamide
CAS :<p>Acetaldophosphamide is a novel stable aldophosphamide analog.</p>Formule :C11H21Cl2N2O6PCouleur et forme :SolidMasse moléculaire :379.17(E/Z)-Ensifentrine
CAS :<p>RPL-554 (LS-193,855) is a dual PDE3/4 inhibitor with bronchodilator and anti-inflammatory properties, in trials for asthma and hay fever by Verona Pharma.</p>Formule :C26H31N5O4Couleur et forme :SolidMasse moléculaire :477.56Y-29794
CAS :<p>Y-29794, a covalent POP inhibitor with a Ki of 0.95 nM, holds research potential for neurodegenerative diseases and cancer.</p>Formule :C22H32N2OS2Couleur et forme :SolidMasse moléculaire :404.63CP-532623
CAS :<p>CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.</p>Formule :C27H27F9N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :598.5YC-001
CAS :<p>YC-001: inverse agonist/antagonist for rod opsin, prevents light-induced retinal degeneration.</p>Formule :C12H7ClO2S2Couleur et forme :SolidMasse moléculaire :282.77YM 26734
CAS :<p>Competitive inhibitor of secretory phospholipase A2 (sPLA2)</p>Formule :C45H62O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.97Imidazoleacetic acid
CAS :<p>Imidazoleacetic acid, an endogenous ligand, stimulates imidazole receptors.</p>Formule :C5H6N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :126.11LAS-31180
CAS :<p>LAS-31180 is a phosphodiesterase 3 inhibitor. It also has positive inotropic and vasodilator properties.</p>Formule :C11H12N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :252.29DMPAC-Chol
CAS :<p>DMPAC-Chol, a cationic cholesterol, aids gene transfection, DNA protection, binds DNA, and lowers HepG2 viability at 37.5 μg/ml.</p>Formule :C33H58N2O2Couleur et forme :SolidMasse moléculaire :514.83hCAIX-IN-7
CAS :<p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).</p>Formule :C18H12FNO3Couleur et forme :SolidMasse moléculaire :309.29JNJ-40413269
CAS :<p>JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.</p>Formule :C19H15ClF3N3OCouleur et forme :SolidMasse moléculaire :393.79SHP2-IN-13
CAS :<p>SHP2-IN-13 is an orally active, highly selective allosteric inhibitor targeting the SHP2 “tunnel site,” exhibiting an IC50 of 83.0 nM.</p>Formule :C16H21N7OCouleur et forme :SolidMasse moléculaire :327.38ML202
CAS :<p>ML202 activates human pyruvate kinase M2, affecting PEP cooperativity with minimal impact on ADP binding.</p>Formule :C18H17N3O3S2Couleur et forme :SolidMasse moléculaire :387.48Xanthine oxidoreductase-IN-1
CAS :<p>Xanthine oxidoreductase-IN-1 is a xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 7.0 nM.</p>Formule :C18H20N4O2Couleur et forme :SolidMasse moléculaire :324.38SCD1-IN-1
CAS :<p>SCD1-IN-1, a potent inhibitor of SCD1 (IC50: 5.8 nM), is valuable in dermatologic research [1].</p>Formule :C20H20F3NO4Couleur et forme :SolidMasse moléculaire :395.37SQ 28853
CAS :<p>SQ 28853 is an inhibitor of ACE with diuretic properties.</p>Formule :C19H25ClN4NaO6S3Couleur et forme :SolidMasse moléculaire :560.05RORγt Inverse agonist 8
CAS :<p>RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with an IC50 of 19 nM).</p>Formule :C26H33N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.59GNE-3500
CAS :<p>GNE-3500: potent, selective RORc inverse agonist; orally bioavailable; promising for treating inflammatory diseases.</p>Formule :C24H30FN3O3SCouleur et forme :SolidMasse moléculaire :459.58YM-75466
CAS :<p>YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.</p>Formule :C28H35N5O8S2Couleur et forme :SolidMasse moléculaire :633.74HX-600
CAS :<p>HX-600 is a synthetic agonist for the RXR-Nurr1 heterodimer complex. HX-600 prevents ischemia-induced neuronal damage.</p>Formule :C29H30N2O2Couleur et forme :SolidMasse moléculaire :438.56MB-07729
CAS :<p>MB-07729 inhibits fructose-1,6-bisphosphate with IC50: 189 nM (rat), 121 nM (monkey), 31 nM (human) for diabetes research.</p>Formule :C12H15N2O5PSDegré de pureté :99.54% - 99.64%Couleur et forme :SolidMasse moléculaire :330.3Trandolaprilat
CAS :<p>Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme.</p>Formule :C22H30N2O5Couleur et forme :Pale Yellow SolidMasse moléculaire :402.48(Rac)-3′-Hydroxy simvastatin
CAS :<p>(Rac)-3′-Hydroxy Simvastatin, a metabolite of Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, demonstrating a K i value of 0.2 nM.</p>Formule :C25H38O6Couleur et forme :SolidMasse moléculaire :434.5711β-HSD1-IN-12
CAS :<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Formule :C19H27ClN2O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :398.95BMS 740808
CAS :<p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>Formule :C31H27F3N6O3Couleur et forme :SolidMasse moléculaire :588.58TMCB
CAS :<p>CK2 and ERK8 inhibitor</p>Formule :C11H9Br4N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.82α-Glucosidase-IN-20
CAS :<p>α-Glucosidase-IN-20 (Compound 3B) is a highly effective and orally active inhibitor of α-glucosidase.</p>Formule :C23H21NOSCouleur et forme :SolidMasse moléculaire :359.48Lp-PLA2-IN-11
CAS :<p>Lp-PLA2-IN-11, a potent Lp-PLA2 inhibitor, may be explored for atherosclerosis and Alzheimer's (WO2014114249A1, E145).</p>Formule :C22H20F4N4O3Couleur et forme :SolidMasse moléculaire :464.41AGI-14100
CAS :<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formule :C29H22ClF4N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :599.96Chaetomellic acid A
CAS :<p>Chaetomellic acid A inhibits farnesyltransferase (IC50=55nM), not active in cells, and selective over geranylgeranyltransferases (IC50: 92µM, 34µM).</p>Formule :C19H34O4Couleur et forme :SolidMasse moléculaire :326.47DHODH-IN-21
CAS :<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formule :C20H19ClF4N6O4Couleur et forme :SolidMasse moléculaire :518.85LEO-29102
CAS :<p>LEO-29102: Potent, selective PDE4 inhibitor, promising for treating skin diseases, phase 2 efficacy in atopic dermatitis.</p>Formule :C20H22Cl2N2O5Couleur et forme :SolidMasse moléculaire :441.31HIF-PHD-IN-2
CAS :<p>HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].</p>Formule :C17H15N5O3SCouleur et forme :SolidMasse moléculaire :369.4α-Amylase-IN-2
CAS :α-Glucosidase-IN-3, an oxime ester derivative of oleanolic acid (OA), exhibits inhibitory activity against α-glucosidase (IC50 = 1.28 µM) and α-amylase (IC50 =Formule :C39H52BrNO4Couleur et forme :SolidMasse moléculaire :678.74Glucosylceramide synthase-IN-1
CAS :<p>Potent oral GCS inhibitor T-036, crosses BBB, targets human (IC50: 31 nM) and mouse GCS (IC50: 51 nM), for Gaucher disease research.</p>Formule :C24H20F4N2O3Couleur et forme :SolidMasse moléculaire :460.42PF-04822163
CAS :<p>PF-04822163 is a potent inhibitor of PDE1 with IC50 value of 0.0024 μM.</p>Formule :C19H17ClN2O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :340.8α-Glycosidase-IN-1
CAS :<p>α-Glycosidase-IN-1 (compound MZ7) is a potent inhibitor of α-GLY (α-glycosidase) (IC50: 44.72 nM, Ki: 44.74 nM).</p>Formule :C21H19N9O6S2Couleur et forme :SolidMasse moléculaire :557.56Agn 190727
CAS :<p>Agn 190727 is a retonoic acid receptor that can induce retinoid-induced hypertriglyceridemia.</p>Formule :C20H22O2Couleur et forme :SolidMasse moléculaire :294.39SLC26A3-IN-3
CAS :<p>SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1].</p>Formule :C20H17IO5Couleur et forme :SolidMasse moléculaire :464.25SPK-601
CAS :SPK-601 is an inhibitor of phosphatidylcholine-specific phospholipase C.Formule :C11H16KOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.47GNX-865
CAS :<p>GNX-865 is an inhibitor of mitochondrial permeability transition pore (mtPTP).</p>Formule :C16H14ClNO3Couleur et forme :SolidMasse moléculaire :303.74CX08005
CAS :<p>CX08005 inhibits PTP1B, cuts liver fat, and improves microcirculation in NAFLD.</p>Formule :C28H39NO4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :453.61RYL-552
CAS :<p>RYL-552 is a potent inhibitor of PfNDH2.</p>Formule :C24H17F4NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.39Disulfamide
CAS :<p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>Formule :C7H9ClN2O4S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :284.74HIF-1α-IN-3
CAS :<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Formule :C19H17N5O2Couleur et forme :SolidMasse moléculaire :347.37VU0155056
CAS :<p>VU0155056 is a dual PLD1/2 inhibitor with IC50 < 1 µM in cellular assays, inhibits breast cancer cell invasion.</p>Formule :C25H26N4O2Degré de pureté :98.6% - 99.15%Couleur et forme :SolidMasse moléculaire :414.5α-Glucosidase-IN-9
CAS :<p>α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].</p>Formule :C19H12N4OSCouleur et forme :SolidMasse moléculaire :344.39Metyltetraprole
CAS :<p>Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.</p>Formule :C19H17ClN6O2Couleur et forme :SolidMasse moléculaire :396.83Delapril
CAS :<p>Delapril is an ACE inhibitor. It blocks the conversion of angiotensin I to angiotensin II.</p>Formule :C26H32N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.54Liarozole HCl
CAS :<p>Liarozole HCl: antineoplastic, boosts ATRA levels, impedes cell growth, promotes differentiation, aromatase inhibitor.</p>Formule :C17H14Cl2N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.23Umbralisib sulfate
CAS :<p>Umbralisib sulfate, an oral dual PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), targets CLL T cells for blood cancer research.</p>Formule :C31H26F3N5O7SCouleur et forme :SolidMasse moléculaire :669.63GKA-71
CAS :<p>GKA-71 is an effective glucokinase activator (GKA).</p>Formule :C21H23N3O6S2Couleur et forme :SolidMasse moléculaire :477.55JNJ-61803534
CAS :<p>JNJ-61803534: RORγt inverse agonist, IC50=9.6 nM, oral, anti-inflammatory, reduces IL-17A in T cells.</p>Formule :C23H23Cl2F6N3O4SCouleur et forme :SolidMasse moléculaire :622.41Umbralisib tosylate
CAS :<p>Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.</p>Formule :C38H32F3N5O6SCouleur et forme :SolidMasse moléculaire :743.75MDK-4823
CAS :<p>MDK-4823 (LMPTP inhibitor1) blocks LMPTP, fighting insulin resistance and diabetes in obesity.</p>Formule :C28H36N4OCouleur et forme :SolidMasse moléculaire :444.61Enpp-1-IN-8
CAS :<p>Enpp-1-IN-8: potent inhibitor of enpp-1, an enzyme breaking down various nucleotide bonds; potential in cancer/infectious disease research.</p>Formule :C19H26N6O4SCouleur et forme :SolidMasse moléculaire :434.51
