Métabolisme

Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.

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8626 produits trouvés pour "Métabolisme"

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Vimirogant hydrochloride
Vimirogant (VTP-43742) HCl: Oral, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM), >1000x selectivity over RORα/β, targets Th17, not Th1/2/Treg.
Formule :C₂₇H₃₆ClF₃N₄O₃S
Couleur et forme :Solid
Masse moléculaire :588.21487
Ref: TM-T64300
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FXIa-IN-6
CAS :
- 1551460-43-5
FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.
Formule :C₃₁H₂₉ClF₂N₄O₄
Couleur et forme :Solid
Masse moléculaire :595.04
Ref: TM-T39035
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Pyripyropene A
CAS :
- 147444-03-9
Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).
Formule :C₃₁H₃₇NO₁₀
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :583.63
Ref: TM-T12592
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α-Glucosidase-IN-14
α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).
Formule :C₂₄H₂₇N₅O₄S₂
Couleur et forme :Solid
Masse moléculaire :513.63
Ref: TM-T63562
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PKR-IN-1
CAS :
- 3057531-75-3
PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).
Formule :C₉HCl₅N₄OS₂
Couleur et forme :Solid
Masse moléculaire :422.525
Ref: TM-T206852
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Casein kinase 1δ-IN-19
CAS :
- 782452-74-8
Casein kinase1δ-IN-19 (compound 492) is a potent inhibitor of casein kinase 1δ. It is utilized in research related to neurodegenerative disorders, such as Alzheimer's disease.
Formule :C₂₁H₁₉N₅O₃
Couleur et forme :Solid
Masse moléculaire :389.407
Ref: TM-T204696
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OH-α-PVP TFA
CAS :
- 1797986-63-0
OH-α-PVP (OH-α-Pyrrolidinovalerophenone) TFA is a metabolite of α-pyrrolidinovalerophenone, which is a synthetic cathinone stimulant.
Formule :C₁₇H₂₄F₃NO₃
Masse moléculaire :347.37
Ref: TM-TN11134
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Lipid PPz-2R1
CAS :
- 2832061-40-0
Lipid PPz-2R1 is an ionizable cationic lipid employed in crafting lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. LNPs with lipid PPz-2R1, encapsulating an mRNA reporter, target the lungs preferentially over the heart, liver, spleen, and kidneys in mice. Additionally, these LNPs, when encapsulating mRNA encoding phosphatase and tensin homolog (PTEN), enhance PTEN protein levels in PTEN-deficient Lewis lung carcinoma (LLC) cells. In an orthotopic murine LLC model, these Lipid PPz-2R1-containing LNPs, carrying PTEN mRNA, reduce tumor growth either when administered alone or alongside an antibody against programmed cell death protein 1 (PD-1).
Formule :C₄₈H₉₄N₂O₄
Masse moléculaire :763.27
Ref: TM-TCL-01231
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GC-IN-2
CAS :
- 333441-43-3
GC-IN-2 (Compound 25) is an effective and selective non-sugar-based glucocerebrosidase inhibitor with an IC50 value of 6.46 μM. It is utilized in research related to Gaucher's disease.
Formule :C₁₉H₁₆N₂O₃S
Couleur et forme :Solid
Masse moléculaire :352.41
Ref: TM-T201201
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EpoY
CAS :
- 245660-13-3
EpoY (SD-142) is an irreversible inhibitor of the primary brain microtubule-associated tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and small vasohibin-binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively reduces the levels of detyrosinated α-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and is linked to potential issues related to cancer and cardiomyopathy.
Formule :C₁₅H₁₇NO₇
Couleur et forme :Solid
Masse moléculaire :323.30
Ref: TM-T201297
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DLCI-1
CAS :
- 2244569-14-8
DLCI-1 is a potent and selective oral inhibitor of cytochrome P450 2A6 (CYP2A6), significantly reducing self-administered nicotine doses in both male and female mice.
Formule :C₁₂H₁₄N₂S
Couleur et forme :Solid
Masse moléculaire :218.32
Ref: TM-T201239
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9-cis-β-Carotene
CAS :
- 13312-52-2
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.
Formule :C₄₀H₅₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :536.87
Ref: TM-T13524
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2,4-Dihydroxybutanoic acid
CAS :
- 1518-62-3
2,4-Dihydroxybutanoic acid is typically not found in extracts of normal human urine and is present only in trace amounts in newborns, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.
Formule :C₄H₈O₄
Couleur et forme :Solid
Masse moléculaire :120.10
Ref: TM-T201260
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LRAT-IN-1
CAS :
- 2820064-05-7
LRAT-IN-1 (compound 1) is an inhibitor of lecithin retinol acyltransferase (LRAT) with an IC50 value of 21.1 μM. This compound works by inhibiting the esterification of retinol to form retinyl esters, thereby increasing the availability of retinol in the skin to deliver anti-aging benefits. LRAT-IN-1 is under investigation for its potential use as an anti-aging ingredient in cosmetics.
Formule :C₂₇H₄₇N₅O₅S₂
Couleur et forme :Solid
Masse moléculaire :585.82
Ref: TM-T200759
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Magnesium ionophore III
CAS :
- 119110-38-2
Magnesium ionophore III (ETH 4030) is an ion carrier that regulates intracellular magnesium ion concentrations. It enhances cellular functions and metabolic activities by increasing the permeability of cell membranes to magnesium ions. Additionally, Magnesium ionophore III is utilized in research to explore the significance of magnesium ions in biological processes and their impact on cellular physiology.
Formule :C₃₀H₅₈N₄O₄
Couleur et forme :Solid
Masse moléculaire :538.81
Ref: TM-T201134
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QGC583
CAS :
- 2417001-25-1
QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.
Formule :C₁₃H₂₀NO₅P
Couleur et forme :Solid
Masse moléculaire :301.28
Ref: TM-T200621
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Sphingomyelin (d18:1/12:0)
CAS :
- 474923-21-2
Sphingomyelin (d18:1/12:0) is a polar lipid known for its role in modulating cell signal transduction. It plays a critical role in cell membranes, influencing their fluidity and stability. Additionally, sphingomyelin (d18:1/12:0) is involved in lipid metabolism and has potential in promoting neuronal cell growth. This compound is essential for the functioning and development of the nervous system.
Formule :C₃₅H₇₁N₂O₆P
Couleur et forme :Solid
Masse moléculaire :646.92
Ref: TM-T201049
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AubipyOMe
CAS :
- 1221591-26-9
AubipyOMe serves as an effective inhibitor of Tartrate-resistant Acid Phosphatase (TRAP/ACP5), a metalloenzyme identified in activated osteoclasts and macrophages. It exhibits inhibitory IC50 values of 1.3 μM against TRAP5a and 1.8 μM against TRAP5b. Additionally, it effectively suppresses TRAP activity in extracts from mouse macrophages and human lung tissues.
Formule :C₁₂H₁₂AuCl₂F₆N₂O₂P
Couleur et forme :Solid
Masse moléculaire :629.07
Ref: TM-T201150
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CB30865
CAS :
- 206275-15-2
CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.
Formule :C₂₆H₂₂BrN₅O₂
Degré de pureté :99.04%
Couleur et forme :Solid
Masse moléculaire :516.39
Ref: TM-T14882
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Homomoschatoline
CAS :
- 5140-38-5
Homomoschatoline is an antibacterial isolated from Artabotrys crassifolius.
Formule :C₁₉H₁₅NO₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :321.33
Ref: TM-T25505
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PDE5-IN-8
CAS :
- 1233518-60-9
PDE5-IN-8 (compound 2) is an inhibitor of PDEs.
Formule :C₂₂H₂₀ClN₃O₂
Couleur et forme :Solid
Masse moléculaire :393.87
Ref: TM-T200636
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Zaragozic acid C
CAS :
- 146389-62-0
Zaragozic acid C is an effective inhibitor of squalene synthase.
Formule :C₄₀H₅₀O₁₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :754.82
Ref: TM-T24710
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S-15176
CAS :
- 148089-70-7
S-15176 is an inhibitor of the mitochondrial permeability transition pore (PTP). It effectively suppresses mitochondrial swelling induced by tert-butyl hydroperoxide, with an IC50 value of 45.7 μM. S-15176 prevents the opening of PTP, thus averting the dissipation of mitochondrial membrane potential and the oxidation of NAD(P)H, while enhancing mitochondrial calcium loading capacity. It holds potential for research into ischemia-reperfusion injury.
Formule :C₃₁H₄₈N₂O₄S
Couleur et forme :Solid
Masse moléculaire :544.79
Ref: TM-T207660
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GGACK
CAS :
- 65113-67-9
GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).
Formule :C₁₄H₂₅ClN₆O₅
Masse moléculaire :392.84
Ref: TM-TP3280
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Carbonic anhydrase inhibitor 19
CAS :
- 3033374-40-9
Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.
Formule :C₂₃H₂₅N₃O₆S₂
Masse moléculaire :503.59
Ref: TM-TYD-02781
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α-Glucosidase-IN-43
CAS :
- 3018963-27-1
α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor with an IC50 of 4.32 μM, demonstrating acute blood-glucose-lowering properties. It is safe and effective in vivo, showing no toxicity to normal fibroblasts in mice and can ameliorate diabetes induced by streptozotocin in rats. α-Glucosidase-IN-43 is applicable for research on postprandial hyperglycemia in diabetic patients.
Formule :C₂₇H₃₁N₃O₄
Masse moléculaire :461.55
Ref: TM-T208265
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Mucidin
CAS :
- 52110-55-1
Mucidin is an antifungal antibiotic that inhibits electron transfer reactions within the mitochondrial respiratory chain's cytochrome bc1 complex.
Formule :C₁₆H₁₈O₃
Masse moléculaire :258.31
Ref: TM-T210314
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Z21090
CAS :
- 2992690-71-6
Z21090 (ZL40) is a highly effective inhibitor of PDE 4, exhibiting an IC 50 value of 37.4 nM, and possesses oral bioavailability. It is significant in the study of alcohol-related diseases [1].
Formule :C₁₂H₁₄ClN₃O₃
Couleur et forme :Solid
Masse moléculaire :283.71
Ref: TM-T87655
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NAMPT activator-6
CAS :
- 2237267-86-4
NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].
Formule :C₁₇H₂₁N₅O₃S
Couleur et forme :Solid
Masse moléculaire :375.45
Ref: TM-T86958
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ICMT-IN-55
CAS :
- 1313602-77-5
ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].
Formule :C₂₂H₂₆F₃NO₂
Couleur et forme :Solid
Masse moléculaire :393.44
Ref: TM-T86702
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α-Amylase/α-Glucosidase-IN-7
CAS :
- 1038094-94-8
α-Amylase/α-Glucosidase-IN-7 (Compound 3f) serves as a competitive inhibitor for the enzymes α-glucosidase and α-amylase, exhibiting IC50 values of 18.52 µM and 20.25 µM, respectively. Additionally, it effectively inhibits AChE and BChE, with IC50 values of 9.25 µM and 10.06 µM, respectively. This compound is useful in research related to diabetes and Alzheimer's [1].
Formule :C₁₅H₉Cl₂FN₂OS
Couleur et forme :Solid
Masse moléculaire :355.21
Ref: TM-T87684
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LXRα agonist 1
CAS :
- 1790089-97-2
LXRα agonist 1 (Compound 40) is a selective activator of LXRα, with an EC50 of 42 nM, and also demonstrates some activation effects on LXRβ, with an EC50 of 266 nM. It promotes target gene transcription by stabilizing the ligand-binding domain (LBD) of LXRα. When combined with the Raf inhibitor Sorafenib, LXRα agonist 1 shows significant antitumor activity in liver cancer cells. This compound is applicable in research focused on lipotoxicity-related cancers.
Formule :C₂₈H₂₇N₃O₂
Couleur et forme :Solid
Masse moléculaire :437.533
Ref: TM-T206978
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UGT1A1-IN-1
CAS :
- 2097024-37-6
UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].
Formule :C₂₂H₁₉NO₃
Couleur et forme :Solid
Masse moléculaire :345.39
Ref: TM-T87592
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DC371739
CAS :
- 2135765-21-6
DC371739 is an effective oral PCSK9 inhibitor that decreases both PCSK9 and ANGPTL3 mRNA expression. It also reduces PCSK9 protein expression while enhancing that of LDLR. Given its properties, DC371739 has potential applications in the study of hyperlipidemia.
Formule :C₂₉H₃₀N₂O₄
Couleur et forme :Solid
Masse moléculaire :470.56
Ref: TM-T88735
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Fmoc-NH-PEG6-alcohol
CAS :
- 1884208-29-0
Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Formule :C₂₇H₃₇NO₈
Couleur et forme :Solid
Masse moléculaire :503.58
Ref: TM-T86468
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E234G HYPE-IN-1
CAS :
- 1341007-95-1
Compound I2.10 (E234G HYPE-IN-1) functions as an AMPylase inhibitor and exhibits low cytotoxicity toward human cell lines [1].
Formule :C₁₄H₉N₅O₂
Couleur et forme :Solid
Masse moléculaire :279.25
Ref: TM-T86314
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Tovinontrine
CAS :
- 2062661-53-2
Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.
Formule :C₂₁H₂₆N₆O₂
Degré de pureté :98.14%
Couleur et forme :Solid
Masse moléculaire :394.47
Ref: TM-T61833
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MAGL-IN-20
MAGL-IN-20 (compound ±34) is a reversible inhibitor of monoacylglycerol lipase (MAGL). It exhibits significant antiproliferative activity against a range of cancer cell lines, including H460, HT29, CT-26, Huh7, and HCCLM-3.
Formule :C₂₃H₂₄N₂O
Couleur et forme :Solid
Masse moléculaire :344.45
Ref: TM-T201753
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Nampt-IN-13
CAS :
- 2592504-89-5
Nampt-IN-13 (example 58m) is an NAMPT inhibitor used in the synthesis of antibody-drug conjugates (ADCs).
Formule :C₂₄H₃₀N₆O₂
Couleur et forme :Solid
Masse moléculaire :434.53
Ref: TM-T201106
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Nampt-IN-15
CAS :
- 2222981-61-3
Nampt-IN-15 (Example 3) is a Nampt inhibitor that exhibits cytotoxic effects on various cell lines, including BxPC-3, HepG2, L540cy, and MOLM-13. The respective IC50 values for these cell lines are 38.5 nM, 8 nM, 8.5 nM, and 7 nM.
Formule :C₂₄H₃₀N₄O₂
Couleur et forme :Solid
Masse moléculaire :406.52
Ref: TM-T201167
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RORγt inverse agonist 32
CAS :
- 2301159-96-4
RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.
Formule :C₂₄H₂₈F₃NO₅S
Couleur et forme :Solid
Masse moléculaire :499.54
Ref: TM-T200887
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CK1δ-IN-3
CAS :
- 571174-12-4
CK1δ-IN-3 (compound 376) is a CK1δ (casein kinase 1δ) inhibitor that can be used to study neurodegenerative diseases such as Alzheimer's disease.
Formule :C₂₄H₁₉N₃O₂S
Degré de pureté :99.27%
Couleur et forme :Solid
Masse moléculaire :413.49
Ref: TM-T204344
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AChE/hCA I-IN-1
CAS :
- 155140-19-5
AChE/hCA I-IN-1 (Compound L3) is an inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), effectively inhibiting AChE, hCA I, and hCA II with IC50 values of 302 nM, 265 nM, and 283 nM, respectively.
Formule :C₁₃H₉BrNNaO₄S
Couleur et forme :Solid
Masse moléculaire :378.174
Ref: TM-T204128
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PFM046
CAS :
- 3053859-57-4
PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.
Formule :C₂₉H₄₂O₂
Couleur et forme :Solid
Masse moléculaire :422.643
Ref: TM-T204254
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DC360
CAS :
- 2324152-25-0
DC360 is a synthetic analog of all-trans retinoic acid (ATRA) that can induce the expression of RARβ. It is useful for studies characterizing the retinoic acid signaling pathway.
Formule :C₂₃H₂₃NO₂
Couleur et forme :Solid
Masse moléculaire :345.434
Ref: TM-T204562
+ Info
Dopaminechrome
CAS :
- 39984-17-3
Dopaminechrome (DACHR) is an oxidation product of dopamine that promotes the generation of H2O2 at mitochondrial complex I in the brain in a concentration- and respiration-dependent manner. It possesses neurotoxic properties and can be utilized in Parkinson's disease research.
Formule :C₈H₇NO₂
Couleur et forme :Solid
Masse moléculaire :149.147
Ref: TM-T204340
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ERAP1 modulator-2
CAS :
- 2643320-62-9
ERAP1 modulator-2 (compound 10) is a potent ERAP1 inhibitor with an IC50 value of less than 100 nM.
Formule :C₂₂H₂₅F₃N₂O₄S
Couleur et forme :Solid
Masse moléculaire :470.505
Ref: TM-T204335
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Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.
Formule :C₂₁H₁₈N₂O₄S
Couleur et forme :Solid
Masse moléculaire :394.44
Ref: TM-T61829
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Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].
Formule :C₁₅H₁₇N₃O₃S
Couleur et forme :Solid
Masse moléculaire :319.38
Ref: TM-T60848
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PENAO
CAS :
- 1192411-43-0
PENAO is a potent mitochondrial toxin for tumor cells. It deactivates the mitochondria of tumor cells by targeting the adenine nucleotide translocase in the cell membrane.
Formule :C₁₃H₁₉AsN₂O₅S
Couleur et forme :Solid
Masse moléculaire :390.29
Ref: TM-T207680
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RMGPa-IN-1
CAS :
- 958237-73-5
RMGPa-IN-1 (Compound 10C) is an inhibitor of rabbit muscle glycogen phosphorylase a (RMGPa), exhibiting an IC50 value of 82.5 μM. This compound holds potential for research in diabetes.
Formule :C₃₃H₅₄O₄
Couleur et forme :Solid
Masse moléculaire :514.779
Ref: TM-T206441
+ Info
Diacylglycerol acyltransferase inhibitor-1
CAS :
- 1610800-25-3
Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.
Formule :C₂₁H₂₃N₅O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :377.44
Ref: TM-T11037
+ Info
Docosapentaenoic acid (22n-3) sodium
CAS :
- 2983837-44-9
Docosapentaenoic acid (22n-3) sodium is a component of phospholipids. It exhibits inhibitory activity against α-amylase and α-glucosidase, with IC50 values of 17 μg/mL and 22 μg/mL, respectively. Additionally, Docosapentaenoic acid 22n-3 sodium enhances cell viability and has mild anti-inflammatory effects.
Formule :C₂₂H₃₄NaO₂
Couleur et forme :Solid
Masse moléculaire :353.494
Ref: TM-T206225
+ Info
2R,4S-Sacubitril
CAS :
- 761373-05-1
2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.
Formule :C₂₄H₂₈NO₅₁Ca
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :430.49
Ref: TM-T19112
+ Info
LXR agonist 2
LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR.
Formule :C₃₅H₄₀ClN₃O₃
Couleur et forme :Solid
Masse moléculaire :586.16
Ref: TM-T64148
+ Info
11β-HSD2-IN-2
CAS :
- 1834601-37-4
11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.
Formule :C₂₂H₂₁NO₂
Degré de pureté :99.61%
Couleur et forme :Solid
Masse moléculaire :331.41
Ref: TM-T85382
+ Info
Lumirubin
CAS :
- 83664-21-5
Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.
Formule :C₃₃H₃₆N₄O₆
Couleur et forme :Solid
Masse moléculaire :584.66
Ref: TM-T32951
+ Info
PDE4-IN-6
PDE4-IN-6: Potent PDE4 inhibitor, IC50 - 0.125μM (B), 0.43μM (D), anti-inflammatory, for arthritis research.
Formule :C₂₅H₂₀FNO₅S
Couleur et forme :Solid
Masse moléculaire :465.49
Ref: TM-T62969
+ Info
8-Hydroxychlorpromazine
CAS :
- 3926-67-8
8-Hydroxychlorpromazine is a metabolite of Chlorpromazine that can enhance the hyperglycemic response following glucose loading, suggesting a possible synergistic role in Chlorpromazine-induced glucose metabolism disorders. It holds potential for research into metabolic diseases.
Formule :C₁₇H₁₉ClN₂OS
Couleur et forme :Solid
Masse moléculaire :334.864
Ref: TM-T206182
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AXKO-0046
AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.
Formule :C₂₅H₃₃N₃
Couleur et forme :Solid
Masse moléculaire :375.55
Ref: TM-T61539
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Lp(a)-IN-5
CAS :
- 2924841-79-0
Lp(a)-IN-5 (Compound A) is an orally active inhibitor of lipoprotein (a) [Lp(a)]. It effectively inhibits the assembly of Apo(a) and ApoB proteins, with an IC50 value of 0.41 nM. Lp(a)-IN-5 shows potential for research into diseases associated with elevated plasma Lp(a) levels, such as cardiovascular diseases.
Formule :C₄₃H₅₆N₄O₇
Couleur et forme :Solid
Masse moléculaire :740.927
Ref: TM-T206094
+ Info
TMX-4113
TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].
Formule :C₁₂H₁₂N₄O₂S₂
Couleur et forme :Solid
Masse moléculaire :308.38
Ref: TM-T60740
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ZSH-2208
CAS :
- 2131803-75-1
ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.
Formule :C₂₀H₁₈O₃S
Degré de pureté :99.81%
Couleur et forme :Solid
Masse moléculaire :338.42
Ref: TM-T205434
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VHR-IN-1
CAS :
- 956189-91-6
VHR-IN-1 (Compound SA1) is an effective and selective VHR phosphatase inhibitor with an IC50 of 18 nM. It hinders the proliferation of cervical cancer cells, demonstrating antitumor activity.
Formule :C₂₈H₂₂ClN₃O₅S₃
Couleur et forme :Solid
Masse moléculaire :612.139
Ref: TM-T205319
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SID 24785302
CAS :
- 378197-09-2
SID 24785302 is an inhibitor of hexokinase, which can suppress glycolysis, regulate mitochondrial function, and ultimately inhibit the replication of mutant mitochondrial DNA.
Formule :C₁₄H₁₂N₂O₃S₂
Couleur et forme :Solid
Masse moléculaire :320.387
Ref: TM-T205257
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P5SA-2
CAS :
- 864717-20-4
P5SA-2 is a selective allosteric activator of PPP5C, functioning by modulating the structure of the PPP5C phosphatase domain. At a concentration of 100 μM, it can enhance PPP5C activity by 3.2-fold, with an apparent affinity constant of 7.8 μM. P5SA-2 is applicable in research related to cancer and Alzheimer's disease.
Formule :C₁₇H₁₅ClN₂O₃
Couleur et forme :Solid
Masse moléculaire :330.766
Ref: TM-T204867
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SGK1-IN-6
CAS :
- 3046378-98-4
SGK1-IN-6 (compound 12f) is an SGK1 inhibitor with an IC50 value of 0.39 μM. In PC3 xenograft models using BALB/c nude mice, SGK1-IN-6 effectively hinders tumor growth without causing any observable toxicity.
Formule :C₃₀H₃₀F₃N₅O₄
Couleur et forme :Solid
Masse moléculaire :581.586
Ref: TM-T205289
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Casein kinase 1δ-IN-23
CAS :
- 729579-66-2
Casein kinase1δ-IN-23 (compound 423) is an effective inhibitor of casein kinase1δ. It is applicable in research related to neurodegenerative diseases such as Alzheimer's disease.
Formule :C₁₉H₁₅N₃O₃S
Couleur et forme :Solid
Masse moléculaire :365.406
Ref: TM-T204385
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IMR687
CAS :
- 1430840-90-6
IMR687: a PDE9 inhibitor that could improve memory in Alzheimer's by slowing cGMP hydrolysis.
Formule :C₂₁H₂₆N₆O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :394.47
Ref: TM-T24163
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Lapaquistat
CAS :
- 189059-71-0
Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.
Formule :C₃₁H₃₉ClN₂O₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :603.1
Ref: TM-T15710
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5-Carboxy-2′-deoxycytidine
CAS :
- 1210427-59-0
5-Carboxy-2′-deoxycytidine is a metabolite of Trifluridine.
Formule :C₁₀H₁₃N₃O₆
Couleur et forme :Solid
Masse moléculaire :271.227
Ref: TM-TYD-02090
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Buspirone N-oxide
CAS :
- 220747-81-9
Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone. Buspirone is an orally active 5-HT1A receptor agonist and a dopamine D2 (dopamine D2) autoreceptor antagonist. It is an anxiolytic agent used for research in generalized anxiety disorder.
Formule :C₂₁H₃₁N₅O₃
Couleur et forme :Solid
Masse moléculaire :401.503
Ref: TM-TYD-01953
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LEQ803
CAS :
- 1211441-59-6
LEQ803 (N-DesmethylRibociclib) is a metabolite of the CDK4/6 inhibitor Ribociclib, produced through metabolism by CYP3A4. This compound holds potential applications in the field of oncology.
Formule :C₂₂H₂₈N₈O
Couleur et forme :Solid
Masse moléculaire :420.511
Ref: TM-T206449
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ATX inhibitor 22
ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) (IC50: 218.9 μM) that lacks inhibitory activity against LPAR1.
Formule :C₁₉H₁₇Cl₃F₂N₂O₄S
Couleur et forme :Solid
Masse moléculaire :513.77
Ref: TM-T63564
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CK1δ-IN-8
CAS :
- 438018-70-3
CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.
Formule :C₁₄H₉N₃O₂S₂
Couleur et forme :Solid
Masse moléculaire :315.37
Ref: TM-T205649
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BT-114143
CAS :
- 2796343-04-7
BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.
Formule :C₈H₁₁N₂O₃P
Couleur et forme :Solid
Masse moléculaire :214.158
Ref: TM-T206847
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Propofol sulfate sodium
CAS :
- 2748343-63-5
Propofolsulfate (sodium) is a metabolite of Propofol.
Formule :C₁₂H₁₇NaO₄S
Couleur et forme :Solid
Masse moléculaire :280.316
Ref: TM-TYD-02096
+ Info
Squalestatin 3
CAS :
- 142505-92-8
Squalestatin 3 is an inhibitor of squalene synthase.
Formule :C₂₅H₃₀O₁₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :538.5
Ref: TM-T24826
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7-Hydroxy-4-phenylcoumarin
CAS :
- 2555-30-8
7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.
Formule :C₁₅H₁₀O₃
Couleur et forme :Solid
Masse moléculaire :238.238
Ref: TM-T205432
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Oxoprolintane
CAS :
- 35259-27-9
Oxoprolintane is a metabolite of the psychoactive compound Prolintane. It exhibits activity in modulating the central nervous system and may serve as a potential neuroprotective agent. Oxoprolintane shows promise for research in the field of neurological disorders.
Formule :C₁₅H₂₁NO
Couleur et forme :Solid
Masse moléculaire :231.333
Ref: TM-T206826
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FXR/HSD17B13 modulator 1
CAS :
- 3067566-36-0
FXR/HSD17B13 modulator 1 (compound 6) is an effective modulator of FXR/HSD17B13, playing a significant role in studies related to metabolic dysfunction-associated steatohepatitis (MASH).
Formule :C₂₆H₁₉Cl₂NO₄
Couleur et forme :Solid
Masse moléculaire :480.339
Ref: TM-T204314
+ Info
PPARδ agonist 11
CAS :
- 2982696-04-6
Compound 11, a selective PPARδ agonist, demonstrates an EC50 of 20 nM, indicating its high affinity for PPARδ receptors. This compound efficiently reduces levels of nitric oxide (NO), as well as the pro-inflammatory cytokines TNFα and IL-6 in LPS-stimulated RAW264.7 cells via the NF-κB pathway, showcasing its anti-inflammatory properties. Additionally, Compound 11 exhibits remarkable stability in human liver microsomes and plasma. It significantly ameliorates foot edema induced by Carrageenan, displaying favorable pharmacokinetic properties with a bioavailability of approximately 100%.
Formule :C₁₉H₁₅F₃N₂O₃S₂
Couleur et forme :Solid
Masse moléculaire :440.46
Ref: TM-T200543
+ Info
BAR-2227
CAS :
- 2409154-23-8
BAR-2227 (compound 3a) functions as an FXR agonist and a LIFR inhibitor. It is utilized in the study of liver fibrosis and inflammation.
Formule :C₂₄H₁₇Cl₂NO₄
Couleur et forme :Solid
Masse moléculaire :454.30
Ref: TM-T200662
+ Info
MAFP
CAS :
- 188404-10-6
MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.
Formule :C₂₁H₃₆FO₂P
Couleur et forme :Solid
Masse moléculaire :370.48
Ref: TM-T15948
+ Info
PF-00489791
CAS :
- 853003-48-2
PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.
Formule :C₂₀H₂₈N₈O₄S
Degré de pureté :99.97%
Couleur et forme :Solid
Masse moléculaire :476.55
Ref: TM-T28360
+ Info
BAY-179
CAS :
- 2764880-87-5
BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.
Formule :C₂₃H₂₁N₅OS
Degré de pureté :98.29%
Couleur et forme :Solid
Masse moléculaire :415.51
Ref: TM-T9774
+ Info
ZMC3
CAS :
- 79514-41-3
ZMC3 (NSC328784), a zinc chelator, exhibits properties as a zinc metallochaperone. It shows enhanced sensitivity in cells with the p53-R175H mutation and increases the cellular levels of ROS (reactive oxygen species).
Formule :C₁₇H₂₀N₆Se
Couleur et forme :Solid
Masse moléculaire :387.34
Ref: TM-T201448
+ Info
AChE/CA I-IN-1
AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.
Formule :C₁₄H₁₉NO₆S
Couleur et forme :Solid
Masse moléculaire :329.37
Ref: TM-T201644
+ Info
AChE/BChE-IN-23
AChE/BChE-IN-23 (Compound 6e) is a dual inhibitor of acetylcholinesterase and butyrylcholinesterase, exhibiting IC50 values of 0.91 μM for AChE, 1.19 μM for eqBChE, and 1.01 μM for hBChE. This compound also demonstrates antioxidant properties and inhibits the aggregation of Aβ1-42 and Tau proteins. Moreover, AChE/BChE-IN-23 prevents the activation of microglial cells by inhibiting the release of reactive oxygen species and mitochondrial damage. Additionally, it reduces the levels of the NLRP3 inflammasome in human microglial cells and reverses memory impairment in mice induced by scopolamine.
Formule :C₁₉H₂₁N₅O₃
Couleur et forme :Solid
Masse moléculaire :367.4
Ref: TM-T201792
+ Info
GKA50 quarterhydrate
GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.
Formule :C₂₆H₃₀N₂O₇
Couleur et forme :Solid
Masse moléculaire :469.01
Ref: TM-T63019
+ Info
Glucosylceramide synthase-IN-3
Glucosylceramide synthase-IN-3 (BZ1) is a potent, brain-accessible, oral GCS inhibitor with a 16 nM IC50, relevant for Gaucher's disease study.
Formule :C₂₁H₂₀FN₃O₃
Couleur et forme :Solid
Masse moléculaire :381.4
Ref: TM-T61632
+ Info
Anticancer agent 78
Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.
Formule :C₁₉H₁₄BrNO₄
Couleur et forme :Solid
Masse moléculaire :400.22
Ref: TM-T61919
+ Info
AD013
AD013 is a selective ACE inhibitor and NEP inhibitor with potential anti-hypertensive and cardioprotective benefits.
Formule :C₂₄H₂₈N₂O₅
Couleur et forme :Solid
Masse moléculaire :424.49
Ref: TM-T62288
+ Info
2-Amino-5-methyl-5-hexenoic acid
CAS :
- 73322-75-5
2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.
Formule :C₇H₁₃NO₂
Couleur et forme :Solid
Masse moléculaire :143.184
Ref: TM-T205170
+ Info
RXR antagonist 2
RXR antagonist 2 is a potent antagonist of RXR (Ki: 0.391 μM, Kd: 0.281 μM). RXR antagonist 2 has shown research potential for RXR-related diseases.
Formule :C₂₉H₃₅F₃N₂O₃
Couleur et forme :Solid
Masse moléculaire :516.6
Ref: TM-T63597
+ Info
(E)-10-Hydroxynortriptyline maleate
CAS :
- 74853-74-0
(E)-10-Hydroxy Nortriptyline maleate, a derivative of antidepressant Nortriptyline, eases depression symptoms.
Formule :C₂₃H₂₅NO₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :395.455
Ref: TM-T11135
+ Info
HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.
Formule :C₂₅H₁₈N₆O₂
Couleur et forme :Solid
Masse moléculaire :434.45
Ref: TM-T62452
+ Info
(Rac)-OSMI-1
(Rac)-OSMI-1, a racemate, inhibits OGT (IC50: 2.7 μM) affecting O-GlcNAcylation without changing surface glycans.
Formule :C₂₈H₂₅N₃O₆S₂
Couleur et forme :Solid
Masse moléculaire :563.64
Ref: TM-T63988
+ Info
Gcase activator 2
CAS :
- 2759897-35-1
Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.
Formule :C₂₁H₂₄N₄O₂
Degré de pureté :99.51% - 99.76%
Couleur et forme :Solid
Masse moléculaire :364.44
Ref: TM-T86495
+ Info
Fusarisetin A
CAS :
- 1300041-53-5
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .
Formule :C₂₂H₃₁NO₅
Couleur et forme :Solid
Masse moléculaire :389.49
Ref: TM-T72867
+ Info
IDO1-IN-13
IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.
Formule :C₂₀H₁₆BrN₅O₂S
Couleur et forme :Solid
Masse moléculaire :470.34
Ref: TM-T63034
+ Info
6-trans-12-epi-Leukotriene B4
CAS :
- 71548-19-1
6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.
Formule :C₂₀H₃₂O₄
Couleur et forme :Solid
Masse moléculaire :336.47
Ref: TM-T72144
+ Info
trans-Doxercalciferol
CAS :
- 74007-20-8
trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.
Formule :C₂₈H₄₄O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :412.65
Ref: TM-T13197
+ Info
L-Afegostat
CAS :
- 202979-51-9
L-Afegostat (5-epi-Isofagomine), an iminosugar, inhibits glycosidase and β-Glucosidase (K i 30 μM), aids in carbohydrate synthesis.
Formule :C₆H₁₃NO₃
Couleur et forme :Solid
Masse moléculaire :147.17
Ref: TM-T72998
+ Info
α-Amylase-IN-10
CAS :
- 3061941-94-1
α-Amylase-IN-10 (Compound 15n) is an inhibitor of α-Amylase, with an IC50 of 5.00 µM. This compound is applicable for research in type 2 diabetes.
Formule :C₂₁H₁₅ClN₂O₄S
Couleur et forme :Solid
Masse moléculaire :426.873
Ref: TM-T204637
+ Info
Nonsteroidal aromatase inhibitor 1
Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.
Formule :C₂₂H₁₆N₄O₂
Couleur et forme :Solid
Masse moléculaire :368.39
Ref: TM-T61444
+ Info
Retezorogant
CAS :
- 1950570-48-5
Retezorogant is a retinoic acid receptor-related orphan receptor gamma (RORγ) antagonist.
Formule :C₂₃H₃₃ClN₂O₃
Couleur et forme :Solid
Masse moléculaire :420.97
Ref: TM-T62242
+ Info
(-)-Mesembrine
CAS :
- 24880-43-1
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).
Formule :C₁₇H₂₃NO₃
Couleur et forme :Solid
Masse moléculaire :289.37
Ref: TM-T28019
+ Info
NTPDase-IN-3
CAS :
- 2883147-45-1
NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.
Formule :C₂₂H₂₄ClN₃OS₂
Couleur et forme :Solid
Masse moléculaire :446.03
Ref: TM-T62633
+ Info
α-Glucosidase-IN-13
α-Glucosidase-IN-13 is an inhibitor of α-glucosidase (IC50: 5.69 μM).
Formule :C₂₅H₂₈N₄O₃S₂
Couleur et forme :Solid
Masse moléculaire :496.64
Ref: TM-T63361
+ Info
HIF-1α-IN-4
HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.
Formule :C₁₆H₁₂N₂O₃
Couleur et forme :Solid
Masse moléculaire :280.28
Ref: TM-T60524
+ Info
APOL1-IN-3
CAS :
- 2762826-72-0
APOL1-IN-3 is an APOL1 inhibitor used for kidney disease research.
Formule :C₁₆H₁₉F₃N₄O₂S
Couleur et forme :Solid
Masse moléculaire :388.41
Ref: TM-T207131
+ Info
Enpp-1-IN-7
Enpp-1-IN-7: potent enpp-1 inhibitor, broad specificity, potential in cancer/infectious disease research. (WO2021203772A1)
Formule :C₁₈H₁₉N₇O₄S
Couleur et forme :Solid
Masse moléculaire :429.45
Ref: TM-T62368
+ Info
RORγt modulator 5
CAS :
- 2119042-65-6
RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.
Formule :C₂₇H₂₂F₅N₃O₆S
Couleur et forme :Solid
Masse moléculaire :611.54
Ref: TM-T72596
+ Info
Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.
Formule :C₂₄H₂₀ClN₃O₃S
Couleur et forme :Solid
Masse moléculaire :465.95
Ref: TM-T62976
+ Info
NAZ2329
CAS :
- 2809469-05-2
NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) & hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.
Formule :C₂₁H₁₈F₃NO₄S₃
Couleur et forme :Soild
Masse moléculaire :501.56
Ref: TM-T63405
+ Info
RORγt inverse agonist 29
RORγt inverse agonist 29 is a potent, selective, orally active RORγt inverse agonist with an IC50 value of 21 nM.
Formule :C₂₅H₂₄N₂O₅S
Couleur et forme :Solid
Masse moléculaire :464.53
Ref: TM-T62956
+ Info
FAAH/MAGL-IN-2
CAS :
- 2765077-82-3
FAAH/MAGL-IN-2: potent, reversible, oral FAAH & MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.
Formule :C₁₅H₁₃Cl₂N₃O₃S
Couleur et forme :Solid
Masse moléculaire :386.25
Ref: TM-T61707
+ Info
L-Sepiapterin
CAS :
- 17094-01-8
L-Sepiapterin aids in making BH4, a coenzyme essential for eNOS, enhancing artery function and angiogenesis, while suppressing ovarian cancer cell growth.
Formule :C₉H₁₁N₅O₃
Couleur et forme :Solid
Masse moléculaire :237.22
Ref: TM-T38250
+ Info
FXIa-IN-9
CAS :
- 2816108-87-7
FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.
Formule :C₂₃H₁₈Cl₂F₃N₉O₂
Couleur et forme :Solid
Masse moléculaire :580.35
Ref: TM-T64099
+ Info
BMS-986339
CAS :
- 2477873-64-4
BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.
Formule :C₃₅H₄₁F₄N₃O₄
Couleur et forme :Solid
Masse moléculaire :643.71
Ref: TM-T73155
+ Info
CYP121A1-IN-1
CYP121A1-IN-1: Strong inhibitor for CYP121A1, hinders Mycobacterium tuberculosis growth (MIC 90 ~6.25 μM), reduces mycocyclosin synthesis.
Formule :C₂₂H₂₀N₄O
Couleur et forme :Solid
Masse moléculaire :356.42
Ref: TM-T61287
+ Info
Rostratin B
CAS :
- 752236-17-2
Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.
Formule :C₁₈H₂₀N₂O₆S₂
Couleur et forme :Solid
Masse moléculaire :424.49
Ref: TM-T73063
+ Info
ALOX15-IN-1
ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.
Formule :C₂₄H₃₁N₃O₅S
Couleur et forme :Solid
Masse moléculaire :473.59
Ref: TM-T63075
+ Info
Keto lovastatin
CAS :
- 96497-73-3
Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.
Formule :C₂₄H₃₄O₆
Couleur et forme :Solid
Masse moléculaire :418.523
Ref: TM-T204532
+ Info
sEH inhibitor-2
SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.
Formule :C₂₃H₁₈N₄O₃
Couleur et forme :Solid
Masse moléculaire :398.41
Ref: TM-T61894
+ Info
PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.
Formule :C₂₄H₂₅N₅O₃
Couleur et forme :Solid
Masse moléculaire :431.49
Ref: TM-T62407
+ Info
RORγt inhibitor 2
CAS :
- 2673278-10-7
RORγt Inhibitor 2, a potent inhibitor of RORγt, exhibits an IC50 of 9.2 nM and is utilized in the study of cancer, inflammation, or autoimmune diseases that are
Formule :C₃₁H₃₃F₅N₂O₇S
Couleur et forme :Solid
Masse moléculaire :672.66
Ref: TM-T72595
+ Info
PTP1B-IN-18
PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.
Formule :C₂₆H₁₉N₃O₄S
Couleur et forme :Solid
Masse moléculaire :469.51
Ref: TM-T63022
+ Info
FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.
Couleur et forme :Solid
Ref: TM-T64257
+ Info
PDE4-IN-5
PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.
Formule :C₂₁H₂₈N₂O₃
Couleur et forme :Solid
Masse moléculaire :356.46
Ref: TM-T61295
+ Info
IDO1-IN-14
IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.
Formule :C₁₈H₁₂Cl₂FN₃O₂
Couleur et forme :Solid
Masse moléculaire :392.21
Ref: TM-T61789
+ Info
CAII-IN-2
CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.
Formule :C₁₈H₁₉BrN₄S
Couleur et forme :Solid
Masse moléculaire :403.34
Ref: TM-T61974
+ Info
β-Glucuronidase/hCAII-IN-1
CAS :
- 2816080-17-6
β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50
Formule :C₃₀H₂₁NO₉
Couleur et forme :Solid
Masse moléculaire :539.49
Ref: TM-T63805
+ Info
Lunacalcipol
CAS :
- 250384-82-8
Lunacalcipol is used for the treatment of Secondary Hyperparathyroidism.
Formule :C₂₈H₄₂O₄S
Couleur et forme :Solid
Masse moléculaire :474.7
Ref: TM-T32952
+ Info
RXR antagonist 1
RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.
Formule :C₂₈H₃₃F₃N₂O₃
Couleur et forme :Solid
Masse moléculaire :502.57
Ref: TM-T63415
+ Info
hCAVII/IX-IN-1
CAS :
- 1300714-76-4
hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.
Formule :C₇H₇N₃O₂S₂
Couleur et forme :Solid
Masse moléculaire :229.279
Ref: TM-T204621
+ Info
sEH inhibitor-1
TCPU (sEH inhibitor-1) is a potent oral human sEH blocker with IC50s of 0.4 nM (human) and 5.3 nM (mouse).
Couleur et forme :Solid
Ref: TM-T64291
+ Info
GSK 366
CAS :
- 1953157-39-5
GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).
Formule :C₁₇H₁₆ClN₃O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :361.78
Ref: TM-T11470
+ Info
Lipid 11
CAS :
- 2758820-82-3
Lipid 11 (Compound Lipid 1) is a cationic lipid designed for nucleic acid delivery. It forms lipid nanoparticles (LNPs) through electrostatic interactions with nucleic acids, such as ceDNA. By using its cationic amine groups, Lipid 11 complexes with negatively charged nucleic acids, enabling cellular uptake and release of the nucleic acid cargo. Lipid 11 shows potential for use in the development of gene therapy drug delivery systems.
Formule :C₄₃H₈₅NO₄
Couleur et forme :Solid
Masse moléculaire :680.14
Ref: TM-TCL-01218
+ Info
PTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium, an oral enzyme inhibitor, has potent antidiabetic and anticancer effects, with a 120 nM IC50.
Formule :C₁₂H₁₃BrF₂N₃O₃P
Couleur et forme :Solid
Masse moléculaire :396.12
Ref: TM-T61851
+ Info
BRD2879
CAS :
- 1304750-47-7
BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).
Formule :C₃₀H₃₈FN₃O₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :571.70
Ref: TM-T26898
+ Info
hMAO-B/MB-COMT-IN-2
Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) & MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.
Formule :C₁₇H₁₈N₂O₃
Couleur et forme :Solid
Masse moléculaire :298.34
Ref: TM-T60658
+ Info
CYP1B1-IN-2
CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].
Formule :C₂₀H₁₁F₃O₂
Couleur et forme :Solid
Masse moléculaire :340.3
Ref: TM-T61082
+ Info
hCAII-IN-3
hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.
Formule :C₁₇H₂₁N₃O₃S
Couleur et forme :Solid
Masse moléculaire :347.43
Ref: TM-T61164
+ Info
hCAIX/XII-IN-15
CAS :
- 69141-46-4
hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.
Formule :C₁₇H₁₈O₄S
Couleur et forme :Solid
Masse moléculaire :318.387
Ref: TM-T206751
+ Info
HIF-1/2α-IN-1
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α.
Formule :C₁₇H₁₆N₆O₄
Couleur et forme :Solid
Masse moléculaire :368.35
Ref: TM-T61442
+ Info
PD-224378
CAS :
- 466678-44-4
PD-224378 is the lactam form of glycamine (β-isomer), produced through a Maillard reaction between pregabalin and lactose.
Formule :C₂₀H₃₅NO₁₁
Couleur et forme :Solid
Masse moléculaire :465.492
Ref: TM-TYD-01992
+ Info
Alkannin
CAS :
- 23444-65-7
Alkannin: potent, tumor-specific PKM2 inhibitor; non-inhibitory to PKM1/PKL; potential anticancer agent.
Formule :C₁₆H₁₆O₅
Couleur et forme :Solid
Masse moléculaire :288.3
Ref: TM-T60581
+ Info
7-APB hydrochloride
CAS :
- 286834-86-4
7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.
Formule :C₁₁H₁₄ClNO
Couleur et forme :Solid
Masse moléculaire :211.688
Ref: TM-TYD-02081
+ Info
PDE4-IN-14
CAS :
- 2231329-25-0
PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including
Formule :C₁₉H₂₀F₂N₄O₃S
Couleur et forme :Solid
Masse moléculaire :422.45
Ref: TM-T79624
+ Info
Lipoxin A5
CAS :
- 110657-98-2
LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.
Formule :C₂₀H₃₀O₅
Couleur et forme :Solid
Masse moléculaire :350.45
Ref: TM-T37459
+ Info
Desmonomethylpromazine
CAS :
- 2095-20-7
Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.
Formule :C₁₆H₁₈N₂S
Couleur et forme :Solid
Masse moléculaire :270.39
Ref: TM-TYD-02518
+ Info
PDHK-IN-5
PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.
Formule :C₃₀H₃₁N₅O₂
Couleur et forme :Solid
Masse moléculaire :493.6
Ref: TM-T63327
+ Info
Casein kinase 1δ-IN-25
CAS :
- 753468-25-6
Casein kinase1δ-IN-25 (compound 487) is a potent inhibitor of casein kinase1δ. It is applicable in research on neurodegenerative diseases such as Alzheimer's disease.
Formule :C₂₀H₁₄FN₃O₄S₂
Couleur et forme :Solid
Masse moléculaire :443.471
Ref: TM-T204238
+ Info
Carbonic anhydrase inhibitor 16
CAS :
- 4479-70-3
Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.
Formule :C₁₄H₁₀N₂O₄S
Degré de pureté :99.65%
Couleur et forme :Solid
Masse moléculaire :302.31
Ref: TM-T86003
+ Info
Fonadelpar
CAS :
- 515138-06-4
Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.
Formule :C₂₅H₂₃F₃N₂O₄S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :504.52
Ref: TM-T15336
+ Info
Homodestcardin
CAS :
- 917382-84-4
Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.
Formule :C₃₂H₅₅N₅O₇
Couleur et forme :Solid
Masse moléculaire :621.81
Ref: TM-T68351
+ Info
α-Amylase-IN-7
CAS :
- 3049575-16-5
α-Amylase-IN-7 (Compound 6e) is an inhibitor of α-Amylase, with an IC50 of 40 μM, indicating its potency. This compound shows potential as an anti-diabetic medication.
Formule :C₁₈H₁₅ClN₆O₂S
Masse moléculaire :414.87
Ref: TM-T210159
+ Info
3'-Hydroxy Repaglinide
CAS :
- 874908-14-2
'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.
Formule :C₂₇H₃₆N₂O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :468.59
Ref: TM-T13497
+ Info
L-739750
CAS :
- 160141-08-2
L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.
Formule :C₂₃H₃₉N₃O₆S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :517.7
Ref: TM-T27773
+ Info
L 731735
CAS :
- 149756-20-7
L 731735 is a farnesyltransferase inhibitor.
Formule :C₁₉H₄₀N₄O₄S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :420.61
Ref: TM-T24351
+ Info
Glucokinase activator 7
CAS :
- 66780-67-4
Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].
Formule :C₁₄H₁₃N₃O₂S
Couleur et forme :Solid
Masse moléculaire :287.337
Ref: TM-T205646
+ Info
PDE4B-IN-3
PDE4B-IN-3 is a potent inhibitor of PDE4B (IC50: 0.94 μM) and exhibits anti-inflammatory effects.
Formule :C₃₀H₃₅N₃O₄S₂
Couleur et forme :Solid
Masse moléculaire :565.75
Ref: TM-T64005
+ Info
RORγ-IN-2
CAS :
- 2088333-58-6
RORγ-IN-2 (Compound 22) is an inhibitor of RORγ, with a Ki value of 16.6 nM for hRORγ. It is useful for research in IL-17-dependent autoimmune diseases.
Formule :C₂₈H₃₂F₃N₅O₄S₂
Couleur et forme :Solid
Masse moléculaire :623.71
Ref: TM-T204411
+ Info
PAT-347
CAS :
- 1689554-51-5
PAT-347 is a potent inhibitor of Autotaxin, an enzyme linked to cell survival and diseases like cancer and fibrosis.
Formule :C₂₈H₂₁ClF₂N₂O₃S
Couleur et forme :Solid
Masse moléculaire :538.99
Ref: TM-T70275
+ Info
PDE4B/7A-IN-1
CAS :
- 2511632-25-8
5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.
Formule :C₂₅H₃₅N₃O₃
Couleur et forme :Solid
Masse moléculaire :425.56
Ref: TM-T62303
+ Info
LXRβ agonist-3
CAS :
- 2413308-63-9
LXRβ agonist-3 is a potent and selective LXRβ (liver X receptor β) agonist (EC50: 0.095 μM).
Formule :C₃₀H₃₃N₃O₆S
Couleur et forme :Solid
Masse moléculaire :563.66
Ref: TM-T63989
+ Info
LTA4H-IN-3
CAS :
- 2707473-09-2
LTA4H-IN-3 (compound 9) functions as an inhibitor of LTA4H, demonstrating an IC50 of 28 nM [1].
Formule :C₁₇H₁₅ClN₄O₃
Couleur et forme :Solid
Masse moléculaire :358.78
Ref: TM-T86828
+ Info
Calcium 2-hydroxypropanoate pentahydrate
CAS :
- 5743-47-5
Calcium 2-hydroxypropanoate (pentahydrate) acts as an activator of the hydroxyl-carboxylic acid receptor 1 (HCAR1) and serves as an epigenetic regulator that induces lysine residue lactylation. This compound, a glycolysis end product, bridges the gap between glycolysis and oxidative phosphorylation and functions as a tumor metabolite with immunoprotective effects of lactate in antitumor immunity.
Formule :C₃H₅O₃CaH₂O
Couleur et forme :Solid
Masse moléculaire :154.147
Ref: TM-T205632
+ Info
Calcipotriol Impurity C
CAS :
- 113082-99-8
Calcipotriol Impurity C is the impurity of Calcipotriol. Calcipotriol is a VDR-like receptors ligand.
Formule :C₂₇H₄₀O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :412.614
Ref: TM-T13590
+ Info
Glycerophosphoglycerol
CAS :
- 6418-92-4
Glycerophosphoglycerol is a precursor in phospholipid synthesis. By enhancing phospholipid formation, it aids in the reconstruction and proliferation of membrane structures in tumor cells. Glycerophosphoglycerol holds promise for research in breast cancer cells.
Formule :C₆H₁₅O₈P
Couleur et forme :Solid
Masse moléculaire :246.15
Ref: TM-TXB-00776
+ Info
Omesdafexor
CAS :
- 2244440-85-3
Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.
Formule :C₃₄H₄₃N₃O₃
Couleur et forme :Solid
Masse moléculaire :541.72
Ref: TM-T63818
+ Info
CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.
Formule :C₁₆H₂₂N₄O₈S
Couleur et forme :Solid
Masse moléculaire :430.43
Ref: TM-T62387
+ Info
Rostratin A
CAS :
- 752236-16-1
Rostratin A, a disulfide from Exserohilum rostratum, is cytotoxic to HCT-116 cells with an IC50 of 8.5 μg/mL.
Formule :C₁₈H₂₄N₂O₆S₂
Couleur et forme :Solid
Masse moléculaire :428.52
Ref: TM-T73062
+ Info
Diethylumbelliferyl phosphate
CAS :
- 897-83-6
Diethylumbelliferyl phosphate (DEUP) is a potent and selective inhibitor of cholesterol esterase that does not inhibit protein kinase A activity in vitro. It disrupts steroidogenesis by blocking cholesterol transport to mitochondria in steroidogenic cells, with an IC50 of 11.6 μM. This compound may also limit the absorption of dietary cholesterol.
Formule :C₁₄H₁₇O₆P
Couleur et forme :Solid
Masse moléculaire :312.25
Ref: TM-T201163
+ Info
PDE4B/7A-IN-2
CAS :
- 2511632-55-4
5-HT1A/5-HT7 antagonist; 5-HT1A Ki=8 nM, 5-HT7 Ki=451 nM; PDE4B IC50=80.4 μM, PDE7A IC50=151.3 μM; stronger than escitalopram.
Formule :C₂₅H₃₅N₃O₂
Couleur et forme :Solid
Masse moléculaire :409.56
Ref: TM-T62064
+ Info
BMS-341400 mesylate
CAS :
- 296250-54-9
BMS-341400 mesylate (Compound 6) is an orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 value of 0.3 nM and is useful in the study of erectile dysfunction.
Formule :C₂₄H₂₆ClN₉O₅S
Couleur et forme :Solid
Masse moléculaire :588.039
Ref: TM-T204188
+ Info
RBM14C12
CAS :
- 1309763-43-6
RBM14C12 is a compound known for its cell signaling activity. It plays a crucial role in researching lipid metabolism and cell membrane structure. Additionally, RBM14C12 can be utilized in the development of novel compounds aimed at modulating the biological mechanisms associated with lipid-related diseases.
Formule :C₂₆H₃₉NO₆
Couleur et forme :Solid
Masse moléculaire :461.59
Ref: TM-T201082
+ Info
Sekikaic Acid
CAS :
- 607-11-4
Sekikaic acid, a phenolic lichen metabolite in H. obscurata, has antioxidant and antiviral properties, inhibiting MLL1-CBP.
Formule :C₂₂H₂₆O₈
Couleur et forme :Solid
Masse moléculaire :418.44
Ref: TM-T69014
+ Info
MDL-100240
CAS :
- 142695-08-7
MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.
Formule :C₂₆H₂₈N₂O₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :480.58
Ref: TM-T28005
+ Info
RORγt Inverse agonist 2
CAS :
- 1801197-92-1
RORγt Inverse agonist 2 is a selective, orally active inverse agonist of RORγt(EC50 of 119 nM).
Formule :C₂₇H₂₅F₈NO₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :627.54
Ref: TM-T12755
+ Info
SHP2-IN-9
SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.
Formule :C₂₀H₂₀FN₃O₂S
Couleur et forme :Solid
Masse moléculaire :385.46
Ref: TM-T61701
+ Info
Anticancer agent 142
CAS :
- 2948338-60-9
Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].
Formule :C₁₃H₁₄BrF₂N₂O₇PS₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :523.26
Ref: TM-T79843
+ Info
(3S,17S)-FD-895
CAS :
- 2598242-04-5
(3S,17S)-FD-895 is an analogue of FD-895. It inhibits the growth of HCT116 cells and shows splicing-modulating activity. This compound can be utilized in cancer research.
Formule :C₃₁H₅₀O₉
Couleur et forme :Solid
Masse moléculaire :566.723
Ref: TM-T204430
+ Info
Thioquinapiperifil dihydrochloride
CAS :
- 204077-66-7
Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.
Formule :C₂₄H₂₉ClN₆OS
Degré de pureté :98.73%
Couleur et forme :Solid
Masse moléculaire :485.05
Ref: TM-T9773
+ Info
1-Stearoyl-sn-glycerol 3-phosphate sodium
CAS :
- 325465-92-7
1-Stearoyl-sn-glycerol 3-phosphate sodium, a biologically active phospholipid, plays a crucial role in regulating cell motility, proliferation, invasion, survival, and the production of growth factors through interactions with G protein-coupled receptors (GPCR). Synthesized during the formation of membrane phospholipids, this compound typically has a low plasma concentration (approximately 100nM) and originates from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its distinctive structure features stearic acid at the sn-1 position and a hydroxyl group at the sn-2 position.
Formule :C₂₁H₄₂NaO₇P
Couleur et forme :Solid
Masse moléculaire :460.52
Ref: TM-T201300
+ Info
D-2-Phosphoglyceric acid
CAS :
- 3443-57-0
D-2-Phosphoglyceric acid is a crucial metabolic intermediate known for its role in enhancing cellular energy metabolism and regulating biosynthesis. It plays a key role in both glycolysis and photosynthesis, which are essential for cellular energy supply. Additionally, D-2-Phosphoglyceric acid serves as a biomarker for monitoring metabolic states in various organisms.
Formule :C₃H₇O₇P
Couleur et forme :Solid
Masse moléculaire :186.06
Ref: TM-T201137
+ Info
LDHA-IN-5
CAS :
- 2776148-90-2
LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary
Formule :C₂₇H₂₂FN₇O₆S₃
Couleur et forme :Solid
Masse moléculaire :655.7
Ref: TM-T73222
+ Info
ZK159222
CAS :
- 156965-15-0
ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.
Formule :C₃₂H₄₈O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :512.72
Ref: TM-T17292
+ Info
Pyrocatechol sulfate
CAS :
- 4918-96-1
Pyrocatechol sulfate, a phenolic metabolite found in human plasma, is associated with the intake of specific foods such as berries and the state of the gut microbiome. It serves as a potential urinary biomarker for kidney function, dialysis clearance rates, whole grain consumption, and regular coffee intake. Additionally, in conjunction with other phenolic sulfates, pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiac cells.
Formule :C₆H₆O₅S
Couleur et forme :Solid
Masse moléculaire :190.17
Ref: TM-T201248
+ Info
TAK-915
CAS :
- 1476727-50-0
TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.
Formule :C₁₉H₁₈F₄N₄O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :458.36
Ref: TM-T16976
+ Info
Epoxykynin
CAS :
- 640263-95-2
Epoxykynin is a potent soluble epoxide hydrolase (sEH) inhibitor [1].
Formule :C₁₉H₂₀BrF₃N₂O₂
Couleur et forme :Solid
Masse moléculaire :445.27
Ref: TM-T86379
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(+)-Potassium Ds-threo-isocitrate monobasic
CAS :
- 20226-99-7
(+)-Potassium Ds-threo-isocitrate monobasic is a bioactive compound known for its role in enhancing cellular metabolism and regulating energy production. This substance is also utilized in researching metabolic pathways and the regulation of enzyme activities. Widely applied in biochemical research, (+)-Potassium Ds-threo-isocitrate monobasic is studied for its potential functions in cellular processes and disease mechanisms.
Formule :C₆H₇KO₇
Couleur et forme :Solid
Masse moléculaire :230.21
Ref: TM-T201097
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(S)-Dexfadrostat
CAS :
- 102676-86-8
(S)-Dexfadrostat ((S)-Fadrozole), an aromatase inhibitor, exhibits an IC 50 of 4.6 nM in in vitro assays using human placental microsomes. It is applicable for research on estrogen-dependent breast cancer, gynecomastia, and systemic lupus erythematosus.
Formule :C₁₄H₁₃N₃
Couleur et forme :Solid
Masse moléculaire :223.27
Ref: TM-T200084
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IDX375
CAS :
- 1162665-52-2
IDX375 is a non-nucleoside inhibitor that selectively targets the HCV NS5B enzyme. It shows promising selectivity for genotypes 1a and 1b. The structure and binding sites of IDX375 have been confirmed through X-ray co-crystallization studies.
Formule :C₂₄H₃₇N₄O₆PS
Couleur et forme :Solid
Masse moléculaire :540.61
Ref: TM-T200982
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NTPDase-IN-1
NTPDase-IN-1 selectively inhibits NTPDases 1, 2, 8 with IC50 of 0.05, 0.23, 0.54 μM. Non-competitive, K m 21 μM, used in cancer, immune, infection research.
Formule :C₁₈H₂₅N₃OS₂
Couleur et forme :Solid
Masse moléculaire :363.54
Ref: TM-T61377
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Casein kinase 1δ-IN-28
CAS :
- 1095750-94-9
Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.
Formule :C₂₃H₂₃FN₆
Couleur et forme :Solid
Masse moléculaire :402.467
Ref: TM-T205129
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Salacinol
CAS :
- 200399-47-9
Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata.
Formule :C₉H₁₈O₉S₂
Couleur et forme :Solid
Masse moléculaire :334.37
Ref: TM-T70002
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hCA XII/II/IX-IN-1
hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.
Formule :C₂₅H₃₄N₄O₇S
Couleur et forme :Solid
Masse moléculaire :534.63
Ref: TM-T63764