Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(270 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(97 produits)
- Lipides(59 produits)
- Lipoxygénase(125 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(164 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8626 produits trouvés pour "Métabolisme"
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m-PEG8-DSPE
<p>m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>Formule :C59H116NO17PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1142.52Chrysophanol triglucoside
CAS :<p>Chrysophanol triglucoside from Cassia obtusifolia, blocks PTP1B (IC50 80.17μM) & α-glucosidase (IC50 197.06μM), may aid diabetes study.</p>Formule :C33H40O19Couleur et forme :SolidMasse moléculaire :740.664cis-Vitamin K1
CAS :<p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>Formule :C31H46O2Couleur et forme :SolidMasse moléculaire :450.70Vitamin K1 2,3-epoxide
CAS :<p>Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle.</p>Formule :C31H46O3Degré de pureté :98% - 98.05%Couleur et forme :SolidMasse moléculaire :466.7Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS :<p>Preterramide C is a fungal metabolite that has been found inA.</p>Formule :C24H23N3O7Couleur et forme :SolidMasse moléculaire :465.46THX6
<p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>Formule :C22H18Cl2N4O2Couleur et forme :SolidMasse moléculaire :441.31Hydroxycotinine
CAS :<p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>Formule :C10H12N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :192.218NU227326
CAS :<p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>Formule :C53H61FN8O7Couleur et forme :SolidMasse moléculaire :941.099ZINC77292789
CAS :<p>ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which</p>Formule :C33H38N2O13Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :670.66(S)-3,4-Dihydroxybutyric acid
CAS :<p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>Formule :C4H8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :120.12-Hydroxyquinoline
CAS :<p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C9H7NOCouleur et forme :White SolidMasse moléculaire :145.15L-Lactate dehydrogenase
CAS :<p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>Couleur et forme :SolidH-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.Formule :C18H31N3O6Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :385.46FXIIa-IN-1 HCl
CAS :<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Formule :C21H17ClN2O6Degré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :428.823-Oxo-7-hydroxychol-4-enoic acid
CAS :<p>3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.</p>Formule :C24H36O4Couleur et forme :SolidMasse moléculaire :388.542,5-Anhydro-D-glucitol-1,6-diphosphate
CAS :<p>2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.</p>Formule :C6H14O11P2Couleur et forme :SolidMasse moléculaire :324.12Galactosylhydroxylysine
CAS :<p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>Formule :C12H24N2O8Couleur et forme :SolidMasse moléculaire :324.33DSPE-PEG2000-PP1
<p>DSPE-PEG2000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide specifically targets inflammatory atherosclerotic plaques. DSPE-PEG2000-PP1 is utilized in drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG1000-LTLRWVGLMS
<p>DSPE-PEG1000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). The receptor for LLRWVGLMS is the chondroitin sulfate proteoglycan NG2. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG1000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG2000-NGR
<p>DSPE-PEG2000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide specifically targets the tumor vasculature antigen CD13. This compound is suitable for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG1000-T7
<p>DSPE-PEG1000-T7 is a PEG compound composed of DSPE and transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR. DSPE-PEG1000-T7 is applicable in drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG5000-M2pep
<p>DSPE-PEG5000-M2pep is a PEG compound composed of DSPE and the M2 macrophage-targeting peptide (M2pep). Serving either as a monovalent or multivalent ligand, M2pep is conjugated with pro-apoptotic peptides to direct toxicity specifically toward M2 macrophages. DSPE-PEG5000-M2pep is applicable for drug delivery.</p>Couleur et forme :Odour SolidIrsogladine maleate
CAS :<p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C9H7Cl2N5Couleur et forme :SolidMasse moléculaire :256.09Sofosbuvir impurity C
CAS :<p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45C12 DG PEG (MW 2000)
<p>C12 DG PEG (1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol) (MW 2000) is a polyethylene glycol lipid that can be utilized in the formation of lipid nanoparticles and liposomes. C12 DG PEG (MW 2000) shows potential for use in cancer research.</p>Couleur et forme :Odour Solid9(S)-HOTrE
CAS :<p>9(S)-HOTrE is a plant metabolite and octadecatrienoic acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid.</p>Formule :C18H30O3Couleur et forme :SolidMasse moléculaire :294.43DSPE-PEG5000-SP94
<p>DSPE-PEG5000-SP94 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (SP94). SP94 demonstrates specific binding affinity to hepatocellular carcinoma (HCC) cells.</p>Couleur et forme :Odour SolidDSPE-PEG5000-F3
<p>DSPE-PEG5000-F3 consists of DSPE and the nucleolin-targeting peptide (F3) and is a PEGylated compound. The F3 peptide specifically binds to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG5000-F3 is applicable for drug delivery.</p>Couleur et forme :Odour SolidL-Amino acid oxidase
CAS :<p>L-Amino acid oxidase catalyzes the oxidative deamination of L-amino acids, which have local oxidative effects as well as potent antimicrobial effects.</p>Couleur et forme :SolidDSPE-PEG2000-pPB
<p>DSPE-PEG2000-pPB is a PEG compound comprised of DSPE and the cyclic oligopeptide (pPB). The pPB component exhibits a high binding affinity for PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG2000-pPB is utilizable for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG1000-CSTSMLKAC
<p>DSPE-PEG1000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. The CSTSMLKAC component facilitates phage-mediated targeting to ischemic cardiac tissue. DSPE-PEG1000-CSTSMLKAC is applicable in drug delivery.</p>Couleur et forme :Odour Solid4'-Methoxyisoagarotetrol
CAS :<p>4'-Methoxyisoagarotetrol, a chromone derivative, exhibits moderate phosphodiesterase 3A (PDE3A) inhibitory activity with an IC50 value of 54 μM [1].</p>Formule :C18H20O7Couleur et forme :SolidMasse moléculaire :348.35Cyclopenol
CAS :<p>Cyclopenol is a natural product that can be used as a reference standard. The CAS number of Cyclopenol is 20007-85-6.</p>Formule :C17H14N2O4Couleur et forme :SolidMasse moléculaire :310.3091α, 25-Dihydroxy VD2-D6
CAS :<p>1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.</p>Formule :C28H44O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.68DSPE-PEG1000-TAASGVRSMH
<p>DSPE-PEG1000-TAASGVRSMH is a PEG compound composed of DSPE and TAASGVRSMH. The TAASGVRSMH sequence exhibits high affinity for the NG2 proteoglycan on PC membranes. DSPE-PEG1000-TAASGVRSMH is useful for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG2000-ESBP
<p>DSPE-PEG2000-ESBP is a PEGylated compound composed of DSPE and E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Couleur et forme :Odour SolidPorcine Factor Xa
CAS :<p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>Couleur et forme :SolidDSPE-PEG5000-T7
<p>DSPE-PEG5000-T7 is a PEG-based compound composed of DSPE and transferrin receptor peptide (T7). T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG5000-T7 is applicable in drug delivery.</p>Couleur et forme :Odour SolidSinbaglustat
CAS :<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formule :C11H23NO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :233.3DSPE-PEG2000-ANG
<p>DSPE-PEG2000-ANG is a PEG compound composed of DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficiency to LRP1 and has been used for targeted delivery to gliomas. DSPE-PEG2000-ANG can be utilized in drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG1000-YIGSR
<p>DSPE-PEG1000-YIGSR is a PEG compound consisting of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP) to enhance adhesion and spreading of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG1000-YIGSR is applicable for drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG5000-ANG
<p>DSPE-PEG5000-ANG is a PEGylated compound formed by DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficacy to LRP1 and has been utilized for targeting glioma delivery. DSPE-PEG5000-ANG is applicable in drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG1000-VIP
<p>DSPE-PEG1000-VIP is a PEG compound composed of DSPE and the vasoactive intestinal peptide (VIP). It can be utilized for drug delivery.</p>Couleur et forme :Odour SolidDSPE-PEG5000-TH
<p>DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.</p>Couleur et forme :Odour SolidDSPE-PEG1000-EB1
<p>DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG3000-TAT
<p>DSPE-PEG3000-TAT is a PEG compound composed of DSPE and a cell-penetrating peptide (TAT). It is used for drug delivery.</p>Couleur et forme :Odour SolidZD-2138
CAS :<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formule :C23H24FNO4Degré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :397.44GGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.13417CP-LC-1422
<p>CP-LC-1422 is a homocysteine-derived ionizable amino lipid known for its efficient RNA delivery capabilities, enabling high-level protein expression in vivo. When formulated in lipid nanoparticles (LNP) and administered intravenously, it demonstrates significant spleen-targeting properties without observed notable toxicity.</p>Formule :C51H97N3O8S3Couleur et forme :SolidMasse moléculaire :975.64378DSPE-PEG2000-T7
<p>DSPE-PEG2000-T7 is a PEG compound composed of DSPE and the transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR, making DSPE-PEG2000-T7 useful for drug delivery applications.</p>Couleur et forme :Odour Solid
