Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(196 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(227 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(133 produits)
- MAO(85 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(170 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(85 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(18 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
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9195 produits trouvés pour "Métabolisme"
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Bicyclic UK18
CAS :Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formule :C77H118N26O25S3Couleur et forme :SolidMasse moléculaire :1904.11PF-1355
CAS :PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
Formule :C14H15N3O4SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :321.35Ref: TM-T3511
2mg35,00€5mg50,00€10mg80,00€25mg116,00€50mg212,00€100mg305,00€200mg437,00€500mgÀ demanderHydroorotic acid
CAS :Hydroorotic acid（Dihydroorotic acid） is an endogenous metabolite，a potential biomarker for diabetic nephropathy and adrenal pheochromocytoma.Formule :C5H6N2O4Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :158.11(2R,3R)-2,3,4-Trihydroxybutanoic acid
CAS :(2R,3R)-2,3,4-Trihydroxybutanoic acid, also known as erythorbic acid, is a naturally occurring organic acid found in various bodily fluids including aqueous humor, urine, plasma, cerebrospinal fluid, and synovial fluid. It is prevalent in both healthy adults and children and is produced through the oxidation of GlcNAc.Formule :C4H8O5Couleur et forme :SolidMasse moléculaire :136.1hMAO-B-IN-5
CAS :hMAO-B-IN-5: potent, selective hMAO-B inhibitor (IC50: 0.12μM), crosses blood-brain barrier, for Parkinson's research.Formule :C24H22O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :358.43Ref: TM-T67879
1mg50,00€5mg92,00€10mg136,00€25mg212,00€50mg296,00€100mg408,00€200mg552,00€1mL*10mM (DMSO)107,00€Bazinaprine
CAS :Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression.Formule :C17H19N5ODegré de pureté :99.65% - 99.93%Couleur et forme :SolidMasse moléculaire :309.37Ref: TM-T67789
1mg70,00€5mg159,00€10mg219,00€25mg328,00€50mg442,00€100mg598,00€200mg785,00€1mL*10mM (DMSO)148,00€iso-C15:0 3-OH
CAS :Iso-C15:0 3-OH is a fatty acid that can be isolated from the PLRT strain. PLRT is a rod-shaped, Gram-negative, chemolithoheterotrophic, obligately aerobic bacterium, obtained from the feces of the mollusk Aplysia punctata.Formule :C15H30O3Couleur et forme :SolidMasse moléculaire :258.397Glucoiberin potassium
CAS :Glucoiberin potassium is an active compound.Formule :C11H21KNO10S3Couleur et forme :SolidMasse moléculaire :462.58Corynecin IV
CAS :Corynecin IV is a metabolite similar to chloramphenicol, originally isolated from corynebacteria.Formule :C13H16N2O6Couleur et forme :SolidMasse moléculaire :296.276Epothilone C
CAS :Epothilone C is a polyketide natural product. It is produced through the collaborative action of a nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) molecules within a multi-enzyme system. Epothilone C is utilized in tumor research.Formule :C26H39NO5SCouleur et forme :SolidMasse moléculaire :477.65720-hydroxy Prostaglandin E2
CAS :20-hydroxy PGE2 is a cytochrome P450 metabolite of PGE2, formed via ω-oxidation and β-oxidation.Formule :C20H32O6Couleur et forme :SolidMasse moléculaire :368.46Acifluorfen-sodium
CAS :Acifluorfen-sodium is a herbicide.Formule :C14H6ClF3NNaO5Couleur et forme :White Crystalline PowderMasse moléculaire :383.64(±)-Geosmin
CAS :(±)-Geosmin, a natural compound, is biologically active in producing an earthy aroma. It plays a crucial role in microbial metabolism and is frequently used as a flavoring agent in food and fragrance in air. Additionally, (±)-Geosmin is under investigation for its potential to detect contamination in soil and water bodies.Formule :C12H22OCouleur et forme :SolidMasse moléculaire :182.3ML266
CAS :ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.Formule :C24H22BrN3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :496.35Ref: TM-T8990
1mg50,00€2mg71,00€5mg105,00€10mg166,00€25mg325,00€50mg449,00€100mg652,00€500mg1.369,00€1mL*10mM (DMSO)114,00€Ademetionine, (S)-
CAS :Ademetionine (SAMe) is a universal metabolite and methyl donor involved in methylation of proteins, phospholipids, catecholamines, and DNA.Formule :C15H22N6O5SCouleur et forme :SolidMasse moléculaire :398.44TC HSD 21
CAS :TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formule :C17H12BrNO3S2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :422.32Ref: TM-T13100
1mg39,00€5mg86,00€10mg130,00€25mg225,00€50mg326,00€100mg439,00€200mg592,00€1mL*10mM (DMSO)95,00€308-R-C4-PEG3-C1-Boc
CAS :308-R-C4-PEG3-C1-Boc is an SGK3 ligand-linker conjugate, utilized in the synthesis of PROTAC SGK3 degrader-2.Formule :C39H53FN6O9SCouleur et forme :SolidMasse moléculaire :800.943-Aminobenzoic acid
CAS :Compound PDK0420, with CAS No. 99-05-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0420 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.13α-Amylase/α-Glucosidase-IN-17
α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.Formule :C19H18FNOCouleur et forme :SolidMasse moléculaire :295.354-Hydroxybutan-2-one
CAS :4-Hydroxybutan-2-one is a ketone widely used in biochemical experiments and drug synthesis research.Formule :C4H8O2Couleur et forme :SolidMasse moléculaire :88.11TB-402
TB-402 is a human IgG4 anticoagulant monoclonal antibody that partially inhibits Factor VIII. It exhibits long-lasting antithrombotic effects and can be studied for the prevention of venous thromboembolism (VTE) following total knee replacement (TKR) surgery.Couleur et forme :Odour LiquidDonepezil N-oxide
CAS :Donepezil N-oxide, a donepezil metabolite, inhibits human ChE with 45.5% at 20 μM.Formule :C24H29NO4Couleur et forme :SolidMasse moléculaire :395.49RORγ agonist 2
RORγ agonist2 (Compound 34) is a selective RORγ agonist with an EC50 of 0.03 μM for hRORγ. It significantly inhibits tumor growth in an MC38 tumor mouse model with the same genetic background.Couleur et forme :Odour SolidFmoc-Cys(Acm)-OH
CAS :Fmoc-Cys(Acm)-OH (Fmoc-S-acetamidomethyl-L-cysteine) is a cysteine derivative.Formule :C21H22N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :414.47Methylspinazarin
CAS :Methylspinazarin, a Streptomyces naphthoquinone, selectively inhibits COMT (IC50=0.8μg/ml), lowers blood pressure in hypertensive rats at 50mg/kg.Formule :C11H8O6Couleur et forme :SolidMasse moléculaire :236.18Deacetylsclerotiorin, (-)-
CAS :deacetylsclerotiorin is a new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.Formule :C19H21ClO4Couleur et forme :SolidMasse moléculaire :348.82PPL-100
CAS :PPL-100, a HIV protease inhibitor, is used potentially for the treatment of HIV infection.Formule :C33H45N4O9PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :704.77CYP1B1-IN-7
CAS :CYP1B1-IN-7 is a CYP1B1 inhibitor that can be used in synergy with anticancer compounds for the treatment of cancers.Formule :C19H13ClODegré de pureté :99.49%Couleur et forme :SoildMasse moléculaire :292.76CAY10462
CAS :CAY10462 (CTK8E8405) is an effective and selective inhibitor of the 20-HETE synthase CYP4A11 with an IC50 of 8.8 nM.Formule :C17H27Cl2N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :360.32CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Couleur et forme :Odour SolidTHP1 Lipid
THP1 Lipid is an ionizable lipid utilized in the synthesis of lipid nanoparticles (LNPs) for mRNA delivery to muscle tissue, exhibiting extremely low toxicity. In tdTomato transgenic mice, it facilitates the editing of specific genes in liver tissue. Additionally, THP1 Lipid is employed in vaccine delivery and studies involving CRISPR/Cas9-mediated gene editing.Couleur et forme :Odour Solid8-iso-15-keto Prostaglandin F2β
CAS :8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.471DSPE-PEG3400-CSTSMLKAC
DSPE-PEG3400-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. CSTSMLKAC is capable of mediating phage selective homing to ischemic cardiac tissue. DSPE-PEG3400-CSTSMLKAC can be utilized for drug delivery.Couleur et forme :Odour SolidPROTAC sEH degrader-2
PROTACsEH degrader-2 is a PROTAC degrader that targets soluble epoxide hydrolase (sEH), with pIC50 values of 8.37 (human sEH-H) and 7.12 (mouse sEH-H). It is applicable for research into inflammation and neuroinflammation-related diseases, such as Alzheimer's disease.Couleur et forme :Odour SolidErucylamide
CAS :Erucylamide (13-Docosenamide) is an alkaloid found in Tadehagi triquetrum (L.) H.Ohashi.Formule :C22H43NODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :337.58WVSAV
WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.Formule :C27H40N6O7Couleur et forme :SolidMasse moléculaire :560.64L-Hisidine monohydrocholoride
CAS :L-Hisidine is an essential amino acid for infants and acts as an inhibitor of mitochondrial glutamine transport.Formule :C6H10ClN3O2Couleur et forme :SolidMasse moléculaire :191.62CK1δ/CK1ε liagnd-1
CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.Formule :C21H20F2N6Couleur et forme :SolidMasse moléculaire :394.42VH-N412
CAS :VH-N412 is a carrier-modified neurotrophin (NT) known for its excellent ability to penetrate the blood-brain barrier. This compound actively binds to both low-density lipoprotein receptor (LDLR) and neurotropin receptor 1 (NTSR-1), acting as an inducer of pharmacologically induced hypothermia (PIH). Additionally, VH-N412 exhibits anticonvulsant and neuroprotective properties, making it a valuable agent for research in neurological disorders such as epilepsy.Formule :C94H163N27O24S3Couleur et forme :SolidMasse moléculaire :2151.66α-glucosidase/PTP1B-IN-1
α-glucosidase/PTP1B-IN-1 (compound 8a) is an effective inhibitor of both α-glucosidase and PTP1B, with IC50 values of 66.3 μM and 47.0 μM, respectively. It also exhibits strong inhibitory activity against α-amylase, having an IC50 of 30.62 μM. This compound is capable of binding to the active sites of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 holds potential for reducing postprandial blood glucose levels and may be useful in managing type 2 diabetes.Formule :C23H20Cl2O5Couleur et forme :SolidMasse moléculaire :447.31Wedeloside
CAS :Wedeloside is a biochemical.Formule :C40H55NO13Couleur et forme :SolidMasse moléculaire :757.874SR-4995
CAS :SR-4995 (CID 16016685) is an ABHD5 ligand, directly binding to ABHD5 and stimulating lipolysis by releasing it from PLIN.Formule :C19H21N3O2SCouleur et forme :SoildMasse moléculaire :355.45Petromyzonol
CAS :Petromyzonol: A sea lamprey bile product; key to spawning as a pheromone, detectable at low levels.Formule :C24H42O4Couleur et forme :SolidMasse moléculaire :394.59Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formule :C13H16FeN2O2Couleur et forme :SolidMasse moléculaire :288.12Lysylglutamic acid
CAS :Lysylglutamic acid is a dipeptide composed of the amino acids lysine (Lysine, Lys) and glutamic acid (Glutamic acid, Glu), with an inhibitory constant (Ki) of 1.3 mM for the membrane transport protein PEPT1.Formule :C11H21N3O5Couleur et forme :SolidMasse moléculaire :275.3Inulobiose
CAS :Inulobiose, a difructan disaccharide isolated from Pistacia vera L., demonstrates inhibitory effects on α-glycosidase (α-glycosidase) and α-amylase (α-amylase) activities, with IC50 values of 1.87 and 40.72 mg/mL respectively. It is utilized in research related to diabetes and glomerular filtration rate testing.Formule :C12H22O11Couleur et forme :SolidMasse moléculaire :342.3(Ile8)-Oxytocin acetate
(Ile8)-Oxytocin acetate is a neurohypophysial hormone analog of oxytocin produced in marsupials.Formule :C45H70N12O14S2Couleur et forme :SolidMasse moléculaire :1067.24(rac./meso)-Astaxanthin
CAS :(rac./meso)-Astaxanthin (AstaREAL; AstaXin) is a carotenoid pigment primarily found in marine animals such as shrimp and salmon. It serves as an effective fat-soluble antioxidant.Formule :C40H52O4Couleur et forme :SolidMasse moléculaire :596.84Corynecin V
CAS :Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.Formule :C14H18N2O6Couleur et forme :SolidMasse moléculaire :310.31-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS :Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.
Formule :C40H80NO8PDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :734.04
