Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(196 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(227 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(133 produits)
- MAO(85 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(170 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(85 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(18 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
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9191 produits trouvés pour "Métabolisme"
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H-Met-Val-OH
CAS :H-Met-Val-OH is a dipeptide inhibiting FMO1 and FMO3 and promoting neurite outgrowth, relevant for neuroregenerative and enzymatic modulation studies.Formule :C10H20N2O3SCouleur et forme :SolidMasse moléculaire :248.34WVSAV
WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.Formule :C27H40N6O7Couleur et forme :SolidMasse moléculaire :560.64(rac./meso)-Astaxanthin
CAS :(rac./meso)-Astaxanthin (AstaREAL; AstaXin) is a carotenoid pigment primarily found in marine animals such as shrimp and salmon. It serves as an effective fat-soluble antioxidant.Formule :C40H52O4Couleur et forme :SolidMasse moléculaire :596.841-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS :Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.
Formule :C40H80NO8PDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :734.04N1,N12-Diacetylspermine dihydrochloride
CAS :Diacetylspermine 2HCl, a diacetylated Spermine, is a cancer biomarker linked to the disease's up-regulation.
Formule :C14H32Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.34ACSS2-IN-2
CAS :MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Formule :C21H19F2N3O4Degré de pureté :99.5%Couleur et forme :SoildMasse moléculaire :415.39Ref: TM-T60060
1mg52,00€2mg77,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg334,00€50mg520,00€100mg750,00€Catestatin acetate
Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release.Formule :C109H177N37O28SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :2485.87Xanthine oxidase-IN-11
Xanthine Oxidase-IN-11, an analog of XO8, is an inhibitor of xanthine oxidase (XO) [1].Formule :C10H8N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :204.25D-Threonine
CAS :D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.
Formule :C4H9NO3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :119.12FZQ-21
FZQ-21 (Compound 70P) is an inhibitor of the water-soluble epoxide hydrolase (sEH), with an IC50 value of 4 nM. The IC50 for inhibiting human sEH is 1.5 nM, which is comparable to that of EC5026 (1.7 nM). FZQ-21 is utilized in sepsis research.
Formule :C28H30N4O3Masse moléculaire :470.231791,1,3-Tribromoacetone
CAS :1,1,3-Tribromoacetone (1,1,3-tribromo-2-propanone) is an impurity of methotrexate.Formule :C3H3Br3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.77Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Formule :C19H23ClN4SDegré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :374.93Ref: TM-T27307L
1mg90,00€5mg187,00€1mL*10mM (DMSO)210,00€10mg301,00€25mg477,00€50mg665,00€100mg897,00€200mg1.198,00€PFKFB3-IN-2
CAS :PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.Formule :C14H11NO7SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :337.3Ref: TM-T67874
5mg49,00€1mL*10mM (DMSO)51,00€10mg71,00€25mg110,00€50mg164,00€100mg225,00€200mg330,00€α-Amylase/α-Glucosidase-IN-12
α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase, with IC50 values of 34.52 nM and 24.62 nM, respectively. This inhibitor is designed based on [triazolo[4,3-b][1,2,4]triazine and holds potential for diabetes research.Formule :C19H13F3N6OSMasse moléculaire :430.08236α-Glycerophosphate Dehydrogenase-Triosephosphate
α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TIM). This compound is employed to measure transketolase (TK) activity in erythrocyte hemolysates, which helps in assessing vitamin B deficiency.Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formule :C26H28N4O6S2Masse moléculaire :556.14503UDP-α-D-Glucose sodium hydrate
UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolicFormule :C15H24N2Na2O18P2Couleur et forme :SolidMasse moléculaire :628.28PROTAC NAMPT Degrader-1
PROTACNAMPT Degrader-1 is an effective NAMPT-targeting PROTAC with a DC50 value of 217 nM. It exhibits antiproliferative activity, with an IC50 value of 0.12 μM against A2780 cells.Formule :C57H69N13O8S2Masse moléculaire :1127.48335N-Desmethyl Sildenafil
CAS :N-Desmethyl Sildenafil (UK-103,320) (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5).Formule :C21H28N6O4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :460.55Ref: TM-T36061
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg78,00€25mg142,00€50mg220,00€100mg321,00€200mg477,00€Aldosterone 21-sulfate sodium salt
Aldosterone 21-sulfate sodium salt is a cholesterol metabolite found in urine.Formule :C21H28NaO8SCouleur et forme :SolidMasse moléculaire :463.5α-Glucosidase-IN-65
α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.Formule :C15H14N2O6Masse moléculaire :318.08519α-Glucosidase-IN-50
α-Glucosidase-IN-50 (compound 8) acts as an inhibitor of α-Glucosidase.Formule :C33H28Cl4N6O6SMasse moléculaire :776.05451Fmoc-Cys-Asp10 TFA
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker involved in synthesizing releasable oligopeptide linkers. These releasable linkers are used to deliver drugs to fracture-targeting oligopeptides, thereby reducing the healing time of fractured femurs.Formule :C60H68F3N11O36SMasse moléculaire :1607.35012Antibacterial agent 218
Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.Formule :C30H24N4OSMasse moléculaire :488.16708α-Glucosidase-IN-49
α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.Formule :C21H13F3N4O3S3Masse moléculaire :522.01019α-Glucosidase-IN-46
α-Glucosidase-IN-46 is a potent inhibitor of α-glucosidase, with an IC50 of 26.0 μM. This compound is applicable in the research of Type 2 diabetes.Formule :C35H32N4O5Masse moléculaire :588.23727LYP-8
LYP-8 is a potent NAMPT degrader that achieves a maximum degradation rate of 97% in NAMPT within SKOV-3 cells at a concentration of 0.5 μM. LYP-8 also demonstrates anticancer activity both in vitro and in vivo.Formule :C56H74N8O10SMasse moléculaire :1050.52486IDO1-IN-24
IDO1-IN-24 (compound 2c) inhibits the production of IDO1 during cell assays, with an IC50 value of 17 μM.Formule :C18H22N2O4Masse moléculaire :330.15796AChE/BChE-IN-17
AChE/BChE-IN-17 (compound 8m) is a potent inhibitor of AChE and BChE, displaying IC50 values of 125.06 nM and 119.68 nM, respectively. Additionally, AChE/BChE-IN-17 inhibits α-glucosidase, with an IC50 of 41050 nM.Formule :C28H25N3O4Masse moléculaire :467.18451Human Factor VIIa
HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.α-Amylase/α-Glucosidase-IN-11
α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazoline-indigo hybrid with notable antidiabetic properties. It acts as a competitive inhibitor of the key digestive enzymes α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM). Additionally, it does not penetrate the blood-brain barrier.Formule :C33H40ClN5O5Masse moléculaire :621.2718α-Glucosidase-IN-60
α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.Formule :C23H14N2O5Masse moléculaire :398.09027PROTAC ACC degrader-1
PROTAC ACC degrader-1 (Compound 9b), an Acetyl-CoA Carboxylase degrader, demonstrates remarkable effectiveness, with a potent activity characterized by an IC 50 of 107.8 μg/mL against Aphis craccivora.Formule :C37H42N4O8Couleur et forme :SolidMasse moléculaire :670.75α-Glucosidase-IN-58
α-Glucosidase-IN-58 (Compound 6d) is an α-glucosidase inhibitor with an IC50 of 1.47 μM.Formule :C22H13F3N2OSMasse moléculaire :410.07007Butyryl-Coenzyme A trisodium
Butyryl-Coenzyme A (trisodium) is a microbial metabolite that can be synthesized into butyric acid or butyrate.Formule :C25H39N7Na3O17P3SMasse moléculaire :903.10291PR280
PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.
Formule :C27H49NO4Masse moléculaire :451.36616C16 Lactosylceramide (d18:1/16:0)
CAS :C16 Lactosylceramide, a sphingolipid, modulates cell signaling and is high in insulin-resistant cattle and Niemann-Pick type C1 disease.Formule :C46H87NO13Couleur et forme :SolidMasse moléculaire :862.18Conagenin
CAS :Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.Formule :C10H19NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :249.26(+)-Menthofuran
(+)-Menthofuran is a useful organic compound for research related to life sciences and the catalog number is T125544.Formule :C10H14OCouleur et forme :SolidMasse moléculaire :150.221Cefetamet Hydrochloride
CAS :Cefetamet is a potent antibiotic to treat respiratory and urinary tract infections.Formule :C14H16ClN5O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.89FR106969
CAS :FR106969 is a platelet activating factor antagonist isolated from fungus with anti-inflammatory activity.Formule :C16H22N2O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.49Ciwujianoside D2
CAS :Ciwujianoside D2 is a useful organic compound for research related to life sciences. The catalog number is T126336 and the CAS number is 114892-57-8.Formule :C54H84O22Couleur et forme :SolidMasse moléculaire :1085.24Edoxaban Isomer
CAS :Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Formule :C24H30ClN7O4SCouleur et forme :SolidMasse moléculaire :548.062,3-Dehydrosilybin B
CAS :2,3-Dehydrosilybin B is a useful organic compound for research related to life sciences and the catalog number is T125883.Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.42Kahalalide A
CAS :Kahalalide A has antimycobacterial activity isolated from the mollusk Elysia rufescens.Formule :C46H67N7O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :894.08Evinacumab
CAS :Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.Degré de pureté :100% (SEC-HPLC) - 99.43% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :150 kDaLipstatin
CAS :Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.Formule :C29H49NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.7Campestanol
CAS :Campestanol is a natural plant sterol from Brassica campestris.Formule :C28H50OCouleur et forme :SolidMasse moléculaire :402.71Bupirimate
CAS :Bupirimate, a systemic fungicide for powdery mildew in roses and apples, belongs to pyrimidines.Formule :C13H24N4O3SDegré de pureté :99.56%Couleur et forme :Emulsifiable LiquidMasse moléculaire :316.42LY 135114
CAS :LY 135114 is a metabolite of LY 195448, which is a phenethanolamine with anti-tumour activity.Formule :C20H26N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.43
