Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(227 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(133 produits)
- MAO(85 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(85 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(18 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9186 produits trouvés pour "Métabolisme"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
SHP2-IN-34
CAS :SHP2-IN-34 (compound A8) is a phenylurea SHP2 inhibitor with anti-cancer properties. It significantly suppresses tumor growth in CT26 mouse models.Formule :C23H25Cl2N7OSCouleur et forme :SolidMasse moléculaire :518.46Rubratoxin B
CAS :Rubratoxin B is a mycotoxin that causes hypoglycemia and fatty liver and has exhibited anticancer activity.Formule :C26H30O11Degré de pureté :98%Couleur et forme :Long Lathes; Hexagonal Plates From Amyl Acetate SolidMasse moléculaire :518.511,3-Dipalmitoleoyl-rac-glycerol
CAS :1,3-Dipalmitoleoyl-rac-glycerol: a diacylglycerol inhibiting yeast α-glucosidase over rat's (IC50s: 4.45 vs 9326.5 μM). Used to study membrane potentials.Formule :C35H64O5Couleur et forme :SolidMasse moléculaire :564.892Methylbenzethonium chloride hydrate
CAS :Methylbenzethonium chloride hydrate exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Additionally, it is utilized as a preservative in cosmetics and pharmaceutical formulations to inhibit microbial growth.Formule :C28H46ClNO3Couleur et forme :SolidMasse moléculaire :480.124-Hydroxybenzoic acid-d4
CAS :4-Hydroxybenzoicacid-d4 is a deuterated form of 4-Hydroxybenzoicacid, which is a phenolic derivative of benzoic acid. It is effective in inhibiting most Gram-positive bacteria and some Gram-negative bacteria with an IC50 of 160 μg/mL.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :142.15Purpactin A
CAS :Purpactin A is a useful organic compound for research related to life sciences. The catalog number is T126026 and the CAS number is 133806-59-4.
Formule :C23H26O7Couleur et forme :SolidMasse moléculaire :414.454Etodolac Acyl Glucuronide
CAS :Etodolac acyl glucuronide is an NSAID metabolite formed by UGT1A9, UGT1A10, and UGT2B7 glucuronidation.Formule :C23H29NO9Couleur et forme :SolidMasse moléculaire :463.4831,2,3,6,7,8-Hexachlorodibenzofuran
CAS :1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.Formule :C12H2Cl6OCouleur et forme :SolidMasse moléculaire :374.86Ciwujianoside C2
CAS :Ciwujianoside C2 is a useful organic compound for research related to life sciences. The catalog number is T126337 and the CAS number is 114892-56-7.Formule :C60H94O26Couleur et forme :SolidMasse moléculaire :1231.39Reduced Haloperidol
CAS :Reduced haloperidol, an active metabolite of haloperidol, binds dopamine D2/sigma-1 receptors and inhibits neurotransmitter reuptake.
Formule :C21H25ClFNO2Couleur et forme :SolidMasse moléculaire :377.882′,3′-Di-O-acetyl-5′-deoxy-5-fluorocytidine
CAS :2'',3''-Di-O-acetyl-5''-deoxy-5-fuluro-D-cytidine is a derivative of capecitabine.Formule :C13H16FN3O6Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :329.28Imidazole-d4
CAS :Imidazole-d4 is an isotope-labeled variant of imidazole, which is a heterocyclic aromatic compound. Imidazole molecules serve as inhibitors for acetylcholinesterase (AChEI) and xanthine oxidase (XO) and have been utilized as corrosion inhibitors. They display a range of biological activities, including antifungal, antitubercular, anti-inflammatory, antioxidant, and analgesic properties. Imidazole inhibits platelet microsomes from converting endoperoxides (PGG2 and PGH2) into thromboxane A2. Additionally, imidazole derivatives show inhibitory effects on the SARS-CoV-2 3CLpro enzyme, offering potential for research in Alzheimer’s disease, gout, COVID-19, and thrombotic disorders.Formule :C3H4N2Couleur et forme :SolidMasse moléculaire :72.1Octachlorodibenzo-p-dioxin
CAS :Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant with no acute toxicity when administered. In rats, the systemic elimination half-life of Octachlorodibenzo-p-dioxin (50 μg/kg intravenously or 50-5000 μg/kg orally) is 3-5 months. It can accumulate and concentrate in the liver and adipose tissue after low-dose, repeated exposure. Repeated dosing of Octachlorodibenzo-p-dioxin leads to increased activity of 7-ethoxyresorufin-O-deethylase (7-EROD) and elevated total cytochrome P-450 levels.Formule :C12Cl8O2Couleur et forme :SolidMasse moléculaire :459.75(±)13(14)-EpDPA
CAS :Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495KOTX1
CAS :KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formule :C17H16FN3O2Couleur et forme :SolidMasse moléculaire :313.33(Iso)-Dehydroemetine
CAS :(Iso)-Dehydroemetine (Dehydroisoemetine, (+/-)-) is a compound with antispasmolytic effect on smooth muscle.
Formule :C29H38N2O4Degré de pureté :98.26% - 98.31%Couleur et forme :SoildMasse moléculaire :478.62Meproscillarin
CAS :Meproscillarin is a glycoside with high bioavailability (about 70%) and an elimination independent of renal function.Formule :C31H44O8Couleur et forme :SolidMasse moléculaire :544.68(±)7(8)-EpDTE
CAS :(±)7(8)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid .Formule :C22H34O3Couleur et forme :SolidMasse moléculaire :346.511MeIQx
CAS :MeIQx, a carcinogenic compound in cooked fish/meat, triggers DNA-reactive metabolites and rat tumors.Formule :C11H11N5Couleur et forme :SolidMasse moléculaire :213.244TNAP-IN-1
CAS :TNAP-IN-1 is a specific inhibitor of tissue-nonspecific alkaline phosphatase (TNAP) and is utilized in studying diseases related to soft tissue calcification.Formule :C17H16N2O4SDegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :344.39Ref: TM-T201911
1mL*10mM (DMSO)À demander1mg40,00€5mg86,00€10mg117,00€25mg230,00€50mg354,00€100mg469,00€3'-sulfo Galactosylsphingosine (ammonium salt)
CAS :Sulfatide derivative inhibits cell migration, adhesion, PKC, cytochrome c; accumulates in metachromatic leukodystrophy; used for LC-MS quantification.Formule :C24H50N2O10SCouleur et forme :SolidMasse moléculaire :558.73UDP-α-D-Glucose sodium hydrate
UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolicFormule :C15H24N2Na2O18P2Couleur et forme :SolidMasse moléculaire :628.28DBPR-110
CAS :DBPR-110: NS5A inhibitor, EC50 of 3.9 pM for HCV1b, SI >12.8 million; EC50 of 228.8 pM for HCV2a, SI >173,130.Formule :C50H48N6O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :861.09Olanzapine N-Oxide
CAS :Olanzapine N-Oxide is a metabolite of Olanzapine which shows antipsychotic activity.
Formule :C17H20N4OSDegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :328.43Angiotensin 1/2 (1-9)
CAS :Angiotensin 1/2 (1-9) is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.Formule :C56H78N16O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1183.32UK-383367
CAS :UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs.Formule :C15H24N4O4Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :324.38N-Trifluoroacetyladriamycin
CAS :N-Trifluoroacetyladriamycin, Valrubicin's metabolite, treats bladder cancer; it's an analog of doxorubicin, infused into the bladder.Formule :C29H28F3NO12Couleur et forme :SolidMasse moléculaire :639.533DHODH-IN-23
CAS :DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88D,L-erythro-PDMP
CAS :D,L-erythro-PDMP inhibits growth in rabbit fibroblasts and blocks UDP-glucose: ceramide glucosyltransferase.Formule :C23H38N2O3Couleur et forme :SolidMasse moléculaire :390.5681,3-Diphenethylurea
CAS :1,3-Diphenethylurea (N,N'-Bis(phenethyl)urea) is a marine derived natural products found in Lissoclinum patella.Formule :C17H20N2ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :268.35trans-hydroxy Glimepiride
CAS :trans-Hydroxy Glimepiride, an active sulfonylurea glimepiride metabolite, is primarily synthesized in the liver by CYP2C9.
Formule :C24H34N4O6SCouleur et forme :SolidMasse moléculaire :506.62Sucunamostat hydrochloride
Sucunamostat (SCO-792) hydrochloride is an orally active, reversible inhibitor of enteropeptidase, displaying inhibition constants (IC50) of 4.6 nM for ratFormule :C22H23ClN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.89Perflubutane
CAS :Perfluorobutane is a gas that is colorless.Formule :C4F10Degré de pureté :98%Couleur et forme :Colorless Gas Colorless GasMasse moléculaire :238.03Adrenocorticotropic Hormone (ACTH) (18-39), human
CAS :ACTH (18-39), or Corticotropin-like Peptide, boosts insulin, amylase, and protein secretion dose-dependently.Formule :C112H165N27O36Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2465.67Deaminocozymase
CAS :Deaminocozymase also known as Nicotinamide-hypoxanthine dinucleotide, is a biochemical.Formule :C21H26N6O15P2Couleur et forme :SolidMasse moléculaire :664.414Sphingomyelins (buttermilk)
CAS :Sphingomyelins, 2-15% of organ phospholipids, are prevalent in brain and nerve sheaths, regulate cholesterol, and turn into ceramides by hydrolysis.
Formule :C46H93N2O6P(fortricosanoyl)Couleur et forme :SolidMasse moléculaire :801.2D-γ-Glutamyl-D-glutamic acid
CAS :D-γ-Glutamyl-D-glutamic acid is a linear polymer with repeating D-glutamic acid units, useful in studies of microbial cell walls and immunological recognition.Formule :C10H16N2O7Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :276.24Hydroxydehydro Nifedipine Carboxylate
CAS :Hydroxydehydro nifedipine carboxylate is a metabolite of nifedipine .1Formule :C16H14N2O7Couleur et forme :SolidMasse moléculaire :346.295Oseltamivir acid methyl ester hydrochloride
CAS :Oseltamivir acid methyl ester hydrochloride, a precursor to oseltamivir, is converted by CES1.Formule :C15H27ClN2O4Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :334.843-keto Fusidic Acid
CAS :3-keto Fusidic acid (3-keto FA) is an active metabolite of the antibiotic fusidic acid .13-keto FA is active againstM. tuberculosis(MIC99= 1.25 μM).
Formule :C31H46O6Couleur et forme :SolidMasse moléculaire :514.70317(R)-HETE
CAS :Kidney sodium transport is partly controlled by 17-HETE, a CYP450 metabolite of arachidonic acid, with the (S) enantiomer inhibiting ATPase at 2 μM.Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473Thymus peptide C
CAS :Thymus peptide C, a hormonal drug derived from the thymus glands of young calves, acts as a substitute for the physiological functions of the thymus.Formule :NADegré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/A16(S)-HETE
CAS :16(S)-HETE, a CYP450 byproduct of arachidonic acid, inhibits kidney tubule ATPase by 60% at 2 μM upon angiotensin II trigger.Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473Glycidamide
CAS :Glycidamide is a carcinogen and metabolite of acrylamide that induces DNA adduct formation and mutations.Formule :C3H5NO2Couleur et forme :SolidMasse moléculaire :87.08Isariin C
CAS :Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.Formule :C28H49N5O7Couleur et forme :SolidMasse moléculaire :567.72Moth Cytochrome C (MCC) (88-103)
CAS :Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.Formule :C79H133N23O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1805.04Mefox
CAS :Mefox is a bioactive chemical.Formule :C20H23N7O7Couleur et forme :SolidMasse moléculaire :473.44AY 9944 dihydrochloride
CAS :AY 9944 dihydrochloride is a intermediate.Formule :C22H30Cl4N2Degré de pureté :99.22% - 99.82%Couleur et forme :SoildMasse moléculaire :464.3C22 Galactosylceramide (d18:1/22:0)
CAS :C22 Galactosylceramide, a CNS sphingolipid, rises in mouse spinal cord on a methionine-restricted diet, found in Alzheimer's hippocampus.Formule :C46H89NO8Couleur et forme :SolidMasse moléculaire :784.20Asperlactone
CAS :Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.Formule :C9H12O4Couleur et forme :SolidMasse moléculaire :184.191
