Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(227 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(134 produits)
- MAO(84 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(84 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(17 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9186 produits trouvés pour "Métabolisme"
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NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.Formule :C56H74N8O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1003.3Glucocerebrosidase
CAS :Glucocerebrosidase (Glucosylceramidase; GBA), a lysosomal enzyme, catalyzes the hydrolysis of the β-glucosidic linkage in glucocerebroside (GC) to yield glucoseDegré de pureté :98%Couleur et forme :SolidEnpp-1-IN-21
CAS :Enpp-1-IN-21 (compound 4g) is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC50 values of 0.45 μM for ENPP1 and 0.19 μM for ENPP3.Formule :C21H16F3NO5SCouleur et forme :SolidMasse moléculaire :451.42Zopiclone impurity-1
CAS :Compound PDK0219, with CAS No. 43200-81-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0219 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C11H7ClN4O2Couleur et forme :Yellow Crystalline PowderMasse moléculaire :262.6516α-Hydroxyetiocholanolone
CAS :16α-Hydroxyetiocholanolone is a metabolite of 16α-hydroxydehydroisoandrosterone (16α-DHEA) and androstenedione.1,2Formule :C19H30O3Couleur et forme :SolidMasse moléculaire :306.446Glisoprenin D
CAS :Glisoprenin D is a useful organic compound for research related to life sciences. The catalog number is T125390 and the CAS number is 205594-89-4.Formule :C45H84O7Couleur et forme :SolidMasse moléculaire :737.16KAT8-IN-1
CAS :Compound 605-62-9, with CAS No. 605-62-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 605-62-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C10H7NO3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :189.17Impurity C of Calcitriol
CAS :Impurity C of Calcitriol is an impurity of Calcitriol.Impurity C of Calcitriol is used in the synthesis of vitamin D3.Formule :C35H49N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :591.78Ninopterin
CAS :Ninopterin is an experimental antineoplastic and folic acid analog.Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.423α-Hydroxysteroid dehydrogenase
CAS :3α-Hydroxysteroid dehydrogenase (3α-HSD), encoded by the AKR1C4 gene, is responsible for catalyzing the transformation of 3-ketosteroids into 3α-hydroxyCouleur et forme :SolidUK 227786
CAS :UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.Formule :C22H22Cl2N4O4Degré de pureté :99.9%Couleur et forme :SoildMasse moléculaire :477.34Ref: TM-T11220L
1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)289,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€NPE-caged-proton
CAS :Generates rapid acidifications down to pH 2Formule :C8H9NNaO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :270.22Deacetylforskolin
CAS :Deacetylforskolin, a diterpene derivative of forskolin, acts on rat adipocytes and lowers hypertensive rats' blood pressure.Formule :C20H32O6Couleur et forme :SolidMasse moléculaire :368.47PF-07238025
PF-07238025, a potent branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with an EC50 of 19 nM, enhances the stability of the BDK-BCKDH core E2Formule :C19H18N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.42MP 518
CAS :MP 518 is a PDE inhibitor with antihypertensive properties. It prevents the degradation of cAMP, leading to increased ICa levels, and counteracts the effects of β-adrenergic stimulation, resulting in vasodilation.Formule :C10H11ClN2O2Couleur et forme :SolidMasse moléculaire :226.66Trichloroacetic acid
CAS :Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.Formule :C2HCl3O2Couleur et forme :SolidMasse moléculaire :163.39Diphenamid
CAS :Diphenamid is a chemical compound from the group of acetamides and a herbicide. The effect is based on the inhibition of acetyl-CoA carboxylase.Formule :C16H17NODegré de pureté :98%Couleur et forme :White Diphenamid Is A Colorless To Off-White Crystals Used As An HerbicideMasse moléculaire :239.31Bromacil
CAS :Bromacil, a substituted uracil herbicide used worldwide, is not readily biodegradable and therefore has consequences to the environment.Formule :C9H13BrN2O2Couleur et forme :SolidMasse moléculaire :261.123-O-methyl-L-DOPA (hydrate)
CAS :3-O-methyl-L-DOPA, a L-DOPA metabolite from catechol O-methyltransferase, may impact or compete with L-DOPA.Formule :C10H15NO5Couleur et forme :SolidMasse moléculaire :229.23Lysinoalanine, (S,R)-
CAS :Lysinoalanine, (S,R)- is a bioactive chemical.Formule :C9H19N3O4Couleur et forme :SolidMasse moléculaire :233.26hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formule :C23H22N4O7S2Couleur et forme :SolidMasse moléculaire :530.573Alanine aminotransferase
CAS :Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-Degré de pureté :98%Couleur et forme :SolidISM012-042
ISM012-042 is an orally active inhibitor of PHD1 and PHD2, with IC50 values of 1.9 and 2.5 nM, respectively. At a concentration of 2.5 μM, ISM012-042 protects Caco-2 cells from DSS-induced barrier damage. Additionally, in LPS-induced bone marrow-derived dendritic cells (BMDC) from mice, ISM012-042 exhibits anti-inflammatory properties by dose-dependently reducing the expression of IL-12 subunit IL-12p35 and TNF. It also restores intestinal barrier function and alleviates intestinal inflammation in various experimental colitis models. ISM012-042 is useful for studying intestinal mucosal repair and immune disorders.Formule :C26H28N6O4Couleur et forme :SolidMasse moléculaire :488.538(R)-AS-1
CAS :(R)-AS-1 is a selective positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2), with an EC50 of 11 nM. At doses of 60 and 90 mg/kg, (R)-AS-1 enhances spontaneous locomotor activity in mice. It demonstrates anticonvulsant properties in mouse seizure models induced by maximal electroshock (MES), pentylenetetrazole (PTZ), or electric current stimulation (32 or 44 mA), with ED50 values of 66.3, 36.3, 15.6, and 41.6 mg/kg, respectively. This compound is applicable in neurological disease research.Formule :C14H16N2O3Couleur et forme :SolidMasse moléculaire :260.294-Hydroxy Atorvastatin calcium salt
CAS :4-Hydroxy Atorvastatin calcium salt is metabolised by cytochrome P450 CYP3A4 and has antimicrobial and anti-microbial activity.
Formule :C66H68CaF2N4O12Couleur et forme :SolidMasse moléculaire :1187.348-iso-13,14-dihydro-15-keto Prostaglandin F2α
CAS :8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits,Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.487β,25-Dihydroxycholesterol
CAS :7β,25-Dihydroxycholesterol, an endogenous metabolite, functions as chemoattractants for immune cells that express EBI2 [1].Formule :C27H46O3Couleur et forme :SolidMasse moléculaire :418.65YM44781
CAS :YM44781: non-peptide antagonist with strong NK1 (pKi=9.09) and NK2 (pKi=9.94) receptor affinity.Formule :C31H32Cl2FN3O2Couleur et forme :SolidMasse moléculaire :568.51Alitame hydrate
CAS :Alitame hydrate is a non-nutritive sweetener that is 2000 times sweeter than sucrose. It is formed from aspartic acid, alanine & an amide.Formule :C14H25N3O4SH2OCouleur et forme :SolidMasse moléculaire :376.4714,15-Leukotriene D4
CAS :14,15-LTD4, an eoxin synthesized by eosinophils, mast cells, and nasal polyps, has modest contractile activity but can increase vascular permeability.Formule :C25H40N2O6SCouleur et forme :SolidMasse moléculaire :496.66α-Glucosidase-IN-79
α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.Formule :C21H22N2O5SCouleur et forme :SolidMasse moléculaire :414.475DPPE-MPEG(2000)
CAS :DPPE-MPEG(2000) is a polyethylene glycol (PEG) derivative of 1,2-dipalmitoyl-rac-glycero-3-phosphoethanolamine (DPPE), characterized as a PEGylated phospholipid.Formule :(C2H4O)nC39H76NO10PCouleur et forme :Solidδ2-cis-Hexadecenoic Acid
CAS :One of the first organisms in which quorum sensing was observed were Myxobacteria, a group of gram-negative bacteria, found mainly in soil and also common toFormule :C16H30O2Couleur et forme :SolidMasse moléculaire :254.418(S)-HEPE
CAS :8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457Sucunamostat
CAS :Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.Formule :C22H22N4O8Couleur et forme :SolidMasse moléculaire :470.438ENPP3 Inhibitor 1
CAS :ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, exhibiting an IC50 value of 0.15 µM, compared to an IC50 of 41.4 µM for ENPP1. It demonstrates antitumor effects against breast and cervical cancers.Formule :C20H14F3NO5SCouleur et forme :SolidMasse moléculaire :437.391,2,3,6,7,8-Hexachlorodibenzofuran
CAS :1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.Formule :C12H2Cl6OCouleur et forme :SolidMasse moléculaire :374.86D-α-Aminocyclohexylacetic acid
CAS :D-α-Aminocyclohexylacetic acid, a glycine derivative, is used as an ergogenic supplement with potential benefits in amino acid and metabolism research.Formule :C8H15NO2Masse moléculaire :157.21Trichlormethiazide (Standard)
CAS :Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.Formule :C8H8Cl3N3O4S2Masse moléculaire :380.66Vitamin K1-d4
CAS :Vitamin K1-d4 is a deuterated compound of Vitamin K1. Vitamin K1 has a CAS number of 84-80-0. Vitamin K1 (Phylloquinone) is a naturally-occurring vitamin. Vitamin K1 is essential for blood clotting, bone and vascular metabolism.Formule :C31H42D4O2Couleur et forme :SoildMasse moléculaire :454.7204Bz-Arg-OEt.HCl
CAS :Bz-Arg-OEt.HCl is an amino acid derivative of L-arginine exhibiting binding activity towards Protein-arginine deiminase type-4 (Km=475.2 µM).Formule :C15H23ClN4O3Degré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :342.82Fmoc-L-glutamic acid 5-tert-butyl ester
CAS :Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.
Formule :C24H27NO6Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :425.474-Isopropoxybenzaldehyde
CAS :ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formule :C10H12O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :164.23-Methyl-2-quinoxalinecarboxylic acid (Standard)
CAS :3-Methyl-2-quinoxalinecarboxylic acid (Standard) is the standard substance of 3-Methyl-2-quinoxalinecarboxylic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 3-Methyl-2-quinoxalinecarboxylic acid has a wide range of applications in life science related research.Formule :C10H8N2O2Couleur et forme :SolidMasse moléculaire :188.18CD3254
CAS :CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.Formule :C24H28O3Degré de pureté :98.71% - 98.71%Couleur et forme :SolidMasse moléculaire :364.48PF-04991532
CAS :PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.Formule :C18H19F3N4O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :396.36Apixaban 13C,d3
CAS :Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormule :C25H25N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.512-Amino-3-(2-chlorophenyl)propanoic acid
CAS :2-Amino-3-(2-chlorophenyl)propanoic acid (2-Chloro-DL-Phenylalanine) is a phenylalanine derivative involved in biometabolism.Formule :C9H10ClNO2Degré de pureté :99.91%Couleur et forme :White PowderMasse moléculaire :199.63Aglepristone
CAS :Aglepristone: synthetic steroid, antiprogestogen, some antiglucocorticoid effect, used as abortifacient in animals.Formule :C29H37NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.62Quizalofop-p-ethyl
CAS :Quizalofop-p-ethyl ((R)-Quizalofop ethyl) is a selective post-emergent herbicide for annual and perennial weeds, acetyl-CoA carboxylase (ACCase) inhibitor.Formule :C19H17ClN2O4Degré de pureté :97.87%Couleur et forme :White Powder CrystalMasse moléculaire :372.80
