Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(164 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8626 produits trouvés pour "Métabolisme"
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Tetomilast
CAS :<p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>Formule :C19H18N2O4SCouleur et forme :SolidMasse moléculaire :370.42Efmoroctocog alfa
CAS :<p>Efmoroctocog alfa, a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc), serves as a therapeutic agent for Hemophilia A research [1].</p>Couleur et forme :SolidSDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Formule :C18H16IN3O3Couleur et forme :SolidMasse moléculaire :449.24L-Arginyl-L-alanine
CAS :<p>L-Arginyl-L-alanine is a dipeptide and acts as a vasodilator derived from vascular smooth muscle. It can elevate the levels of cyclic guanosine monophosphate (cGMP) and nitrite in endothelium-denuded artery rings.</p>Formule :C9H19N5O3Couleur et forme :SolidMasse moléculaire :245.28Menthol glucuronide
CAS :<p>Menthol glucuronide is a metabolite of L-(-)-Menthol, the natural form of Methanol.</p>Formule :C16H28O7Couleur et forme :SolidMasse moléculaire :332.39DSPE-PEG1000-LTLRWVGLMS
<p>DSPE-PEG1000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). The receptor for LLRWVGLMS is the chondroitin sulfate proteoglycan NG2. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG1000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour SolidAminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Formule :C12H16F2N2O4SCouleur et forme :SolidMasse moléculaire :322.07988Propiverine N-oxide
CAS :<p>Propiverine N-oxide is the primary metabolite of propiverine hydrochloride, and it influences bladder contraction and saliva secretion in miniature pigs.</p>Formule :C23H29NO4Couleur et forme :SolidMasse moléculaire :383.48H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.Formule :C18H31N3O6Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :385.46DSPE-PEG2000-NGR
<p>DSPE-PEG2000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide specifically targets the tumor vasculature antigen CD13. This compound is suitable for drug delivery applications.</p>Couleur et forme :Odour Solid1'-Hydroxy bufuralol
CAS :1'-Hydroxy bufuralol is a metabolite of bufuralol, an orally active β-adrenoceptor blocker used in the study of hypertension and cardiac arrhythmias.Formule :C16H23NO3Couleur et forme :SolidMasse moléculaire :277.36Diaphorase
CAS :<p>Diaphorase from anaerobic sludge catalyzes RDX biotransformation via denitrification.</p>Couleur et forme :SolidStephacidin B
CAS :<p>Stephacidin B, from A. ochraceus, forms avrainvillamide in vitro. Cytotoxic to various cancer cells; induces apoptosis in hepatocarcinoma at 4 μM.</p>Formule :C52H54N6O8Couleur et forme :SolidMasse moléculaire :891.038DSPE-PEG2000-PP1
<p>DSPE-PEG2000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide specifically targets inflammatory atherosclerotic plaques. DSPE-PEG2000-PP1 is utilized in drug delivery applications.</p>Couleur et forme :Odour SolidArofylline
CAS :<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Formule :C14H13ClN4O2Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :304.73L-Amino acid oxidase
CAS :<p>L-Amino acid oxidase catalyzes the oxidative deamination of L-amino acids, which have local oxidative effects as well as potent antimicrobial effects.</p>Couleur et forme :SolidSofosbuvir impurity B
<p>Sofosbuvir impurity B, a less active byproduct, inhibits HCV RNA with potent anti-HCV effects.</p>Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45Trityl olmesartan medoxomil impurity III
CAS :<p>Trityl olmesartan medoxomil impurity III is an intermediate impurity in Olmesartan medoxomil synthesis.</p>Formule :C48H42N6O5Couleur et forme :SolidMasse moléculaire :782.88DSPE-PEG3000-TAT
<p>DSPE-PEG3000-TAT is a PEG compound composed of DSPE and a cell-penetrating peptide (TAT). It is used for drug delivery.</p>Couleur et forme :Odour Solid9(S)-HOTrE
CAS :<p>9(S)-HOTrE is a plant metabolite and octadecatrienoic acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid.</p>Formule :C18H30O3Couleur et forme :SolidMasse moléculaire :294.43DSPE-PEG1000-PP1
<p>DSPE-PEG1000-PP1 is a PEG compound composed of DSPE and the PP1 peptide. The PP1 peptide targets inflammatory atherosclerotic plaques. DSPE-PEG1000-PP1 is suitable for drug delivery applications.</p>Couleur et forme :Odour SolidSinbaglustat
CAS :<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formule :C11H23NO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :233.3Monoglyceride lipase
CAS :<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>Couleur et forme :SolidD-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
CAS :<p>D-Ribofuranose 1-phosphate is used to synthesize 5-fluorouracil via uridine phosphorylase.</p>Formule :C11H24NO8PCouleur et forme :SolidMasse moléculaire :329.289AzNue5Ac
CAS :<p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>Formule :C11H18N4O8Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :334.28BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Couleur et forme :Odour SolidPPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Formule :C23H28FN7O3Couleur et forme :SolidMasse moléculaire :469.51ROR1-IN-2
<p>ROR1-IN-2 (compound 9I) is a potent and selective inhibitor of ROR1. It exhibits antiproliferative activity in various cancer cell lines and significantly inhibits tumor growth in vivo.</p>Formule :C30H27N3O4Couleur et forme :SolidMasse moléculaire :493.2001610 FTHF disodium
CAS :<p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>Formule :C20H21N7Na2O7Couleur et forme :SolidMasse moléculaire :517.4ZD-2138
CAS :<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formule :C23H24FNO4Degré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :397.44PP5-IN-2
<p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>Formule :C16H15NO4Couleur et forme :SolidMasse moléculaire :285.29C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS :<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Couleur et forme :SolidPenicillinase
CAS :<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Couleur et forme :SolidADP-specific glucokinase
CAS :<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Couleur et forme :Solid3-O-Dihydro-p-coumaroyltohogenol
<p>3-O-Dihydro-p-coumaroyltohogenol functions as a PTP1B inhibitor (IC50 = 6.27 μM), exhibiting anti-diabetic and anti-obesity activities.</p>Formule :C39H60O5Couleur et forme :SolidMasse moléculaire :608.89Phosphofructokinase
CAS :<p>Phosphofructokinase, a crucial glycolytic enzyme, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolysis pathway. Its activity is inhibited by the binding of Phosphoenolpyruvate (PEP), which regulates the rate of glycolysis. Additionally, Phosphofructokinase is utilized in the measurement of fructose-6-phosphate (fructose-6-phosphate) levels.</p>Couleur et forme :SolidIONIS PTP1BRx
CAS :<p>IONIS PTP1BRx (ISIS 404173) acts as an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). This compound exhibits anti-diabetic properties, making it suitable for research into insulin resistance related to obesity and type 2 diabetes.</p>Couleur et forme :SolidMaurocalcine TFA
<p>Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.</p>Formule :C156H270N56O46S6·xC2HF3O2Couleur et forme :SolidMasse moléculaire :3858.55 (free base)h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formule :C22H30Cl2N6O3Couleur et forme :SolidMasse moléculaire :497.42Tpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Formule :C40H54BrN6O7PSCouleur et forme :SolidMasse moléculaire :873.84SCD1 inhibitor-3
CAS :<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.37Epoxide hydrolase
CAS :<p>Epoxide hydrolase, an enzyme responsible for catalyzing the reaction of epoxides with water to convert epoxy groups into diols, plays a crucial role in the metabolism of environmental pollutants and lipids. It is instrumental in detoxification, inflammatory responses, and regulating the health of the cardiovascular system. Additionally, Epoxide hydrolase is used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, which are important for the synthesis of chiral pharmaceutical molecules.</p>Couleur et forme :SolidESI1
<p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>Formule :C18H18ClN5OCouleur et forme :SolidMasse moléculaire :355.82Diacetinase
Diacetinase, a member of the esterase family, catalyzes the hydrolysis of glyceryl diacetate (Diacetin). It is utilized in the measurement of lipase activity.Couleur et forme :Odour SolidGlycerol-3-phosphate dehydrogenase
CAS :<p>Glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is an enzyme that catalyzes the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP), playing a crucial role in glycerol metabolism and energy production. This enzyme acts as the rate-limiting step in glycerol production within Saccharomyces cerevisiae, regulating glycerol formation and accumulation to aid the yeast in adapting to hyperosmotic environments. Additionally, glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is relevant in research within the field of metabolic engineering.</p>Couleur et forme :SolidDSPE-PEG1000-EB1
<p>DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.</p>Couleur et forme :Odour SolidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.13417PTP1B-IN-22
CAS :<p>PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.</p>Formule :C16H12N2O3S2Degré de pureté :98.35%Couleur et forme :SoildMasse moléculaire :344.41Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS :<p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>Formule :C24H23NO5SDegré de pureté :99.59%Couleur et forme :SoildMasse moléculaire :437.51T3 Acyl glucuronide
CAS :<p>T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite</p>Formule :C21H20I3NO10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :827.1
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