Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(164 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8626 produits trouvés pour "Métabolisme"
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TSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.7983-O-Dihydro-p-coumaroyltohogenol
<p>3-O-Dihydro-p-coumaroyltohogenol functions as a PTP1B inhibitor (IC50 = 6.27 μM), exhibiting anti-diabetic and anti-obesity activities.</p>Formule :C39H60O5Couleur et forme :SolidMasse moléculaire :608.898-iso Prostaglandin A1
CAS :<p>8-iso PGA1: an isoprostane, non-COX prostanoid, minor PGE1 impurity, biological effects unstudied.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472ADP-specific glucokinase
CAS :<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Couleur et forme :SolidPhosphofructokinase
CAS :<p>Phosphofructokinase, a crucial glycolytic enzyme, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolysis pathway. Its activity is inhibited by the binding of Phosphoenolpyruvate (PEP), which regulates the rate of glycolysis. Additionally, Phosphofructokinase is utilized in the measurement of fructose-6-phosphate (fructose-6-phosphate) levels.</p>Couleur et forme :Solid5β-Androstan-3β-ol-17-one
CAS :<p>5β-Androstan-3β-ol-17-one (3β-Etiocholanolone; 5β-Epiandrosterone), a 5β-reduced steroid and a significant metabolic derivative of dehydroepiandrosterone (DHEA</p>Formule :C19H30O2Couleur et forme :SolidMasse moléculaire :290.44MSI-1436 lactate
CAS :<p>MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)</p>Formule :C37H72N4O5SC3H6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1000.17Fellutanine A
CAS :<p>Fellutanine A is a useful organic compound for research related to life sciences. The catalog number is T129801 and the CAS number is 175414-35-4.</p>Couleur et forme :SoildAntibacterial agent 237
<p>Anti bacterial agent 237 (compound Ru-8) acts as a potent antibacterial agent against Staphylococcus aureus, exhibiting minimum inhibitory concentrations (MICs) ranging from 0.78 to 1.56 μg/mL. It works by disrupting bacterial cell membranes, altering their permeability, and inducing the production of reactive oxygen species, which leads to bacterial cell death without promoting resistance. Additionally, Anti bacterial agent 237 demonstrates low hemolytic toxicity towards rabbit erythrocytes and Raw 264.7 cells. It has shown significant antibacterial activity in models of skin wound infections in mice and larval infections by the greater wax moth, effectively combating Staphylococcus aureus infections.</p>Formule :C65H69Cl3N10RuS2Couleur et forme :SolidMasse moléculaire :1261.87DSPE-PEG5000-MPG
<p>DSPE-PEG5000-MPG is a PEG compound composed of DSPE and a peptide carrier (MPG). MPG is derived from the nuclear localization sequence (NLS) of the SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. This compound effectively delivers short oligonucleotides into cells independently of the endosomal pathway.</p>Couleur et forme :Odour SolidImperatoxin A TFA
Imperatoxin A TFA, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, acts as an activator of Ca2+-release channels/ryanodine receptors (RyRs). It facilitates the influx of Ca2+ from the sarcoplasmic reticulum into the cell.Formule :C148H254N58O45S6·xC2HF3O2Couleur et forme :SolidMasse moléculaire :3758.35 (free base)Fumiquinazoline D
CAS :<p>Fumiquinazoline D, from A. fumigatus, inhibits Gram-positive/negative bacteria (MIC 8-16 μg/ml) and F. solani, C. albicans (MIC 32, 64 μg/ml).</p>Formule :C24H21N5O4Couleur et forme :SolidMasse moléculaire :443.46313-cis Acitretin D3
CAS :<p>13-cis Acitretin D3, a deuterium-labeled metabolite of Acitretin, is a second-gen systemic retinoid.</p>Formule :C21H26O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.454N-Demethyl ivabradine hydrochloride
CAS :<p>N-Demethyl Ivabradine Hcl is a specific inhibitor of the funny channel.N-Demethyl Ivabradine Hcl is a metabolite of Ivabradine.</p>Formule :C26H35ClN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.02Anticancer agent 111
<p>Anticancer agent 111 (compound 11), exhibiting anticancer activity, serves as a potent inhibitor of cytochrome P450, particularly targeting CYP3A4 with an</p>Formule :C42H60O4Couleur et forme :SolidMasse moléculaire :628.92Pregnant mare serum gonadotropin
CAS :<p>Pregnant mare serum gonadotropin (PMSG) functions as a gonadotropin that enhances follicular development and ovulation in animals. This compound operates by modulating blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. Commonly employed in livestock to boost reproductive efficiency, PMSG is also valuable for research focused on estrous cycle regulation.</p>Couleur et forme :SolidMethyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate
CAS :<p>Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.</p>Formule :C25H40O4Couleur et forme :SolidMasse moléculaire :404.58Ozolinone
CAS :<p>Ozolinone, an etozoline metabolite, is a loop diuretic treating hypertension and edema.</p>Formule :C11H16N2O3SCouleur et forme :SolidMasse moléculaire :256.322-(Isopentylamino)naphthalene-1,4-dione
CAS :<p>2-(Isopentylamino)naphthalene-1,4-dione: a vitamin K analog inhibiting spasms and seizures in mice with various ED50 values.</p>Formule :C15H17NO2Couleur et forme :SolidMasse moléculaire :243.306NCGC00092410
CAS :<p>NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM.</p>Formule :C21H27N3O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :353.46Febuxostat Acyl Glucuronide
CAS :<p>Febuxostat acyl glucuronide, a febuxostat metabolite, forms through UGTs catalyzed glucuronidation.</p>Formule :C22H24N2O9SCouleur et forme :SolidMasse moléculaire :492.5Amidepsine A
CAS :<p>Amidepsine A is a natural product for research related to life sciences. The catalog number is T22187 and the CAS number is 169181-28-6.</p>Couleur et forme :SolidMasse moléculaire :567.54128-Epirapamycin
CAS :<p>28-Epirapamycin, an impurity of Rapamycin, serves as a potent and specific mTOR inhibitor, exhibiting an IC50 value of 0.1 nM in HEK293 cells [1].</p>Formule :C51H79NO13Couleur et forme :SolidMasse moléculaire :914.173α-Akebonoic Acid
CAS :<p>3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity.</p>Formule :C29H44O3Couleur et forme :SolidMasse moléculaire :440.67MEY-003
<p>MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potency</p>Couleur et forme :Odour Solidα-Glucosidase-IN-24
CAS :<p>α-Glucosidase-IN-24 (Compound 13), an α-Glucosidase inhibitor, exhibits an IC50 value of 451 μM and can be derived from Swertia kouitchensis [1].</p>Formule :C26H30O15Couleur et forme :SolidMasse moléculaire :582.51Creatine kinase (OcCK)
CAS :<p>Creatine kinase (OcCK) converts creatine and ATP into phosphocreatine and ADP, crucial for ATP/ADP balance during high energy demand.</p>Couleur et forme :SolidCellulose
CAS :<p>Cellulose, an excipient, aids stability, solubility, and processing of drugs and affects their ADME.</p>Formule :C12H22O11Couleur et forme :SolidMasse moléculaire :342.2974-Phytase
CAS :<p>4-Phytase is a phosphohydrolase of inositol hexaphosphate [1] .</p>Couleur et forme :SolidAldose 1-epimerase
CAS :<p>Aldose 1-epimerase facilitates the conversion of α- to β-sugars like glucose, crucial for carbohydrate processing.</p>Couleur et forme :Solid(R,S)-Carvedilol Glucuronide
CAS :<p>(R,S)-Carvedilol glucuronide is a racemic mix, metabolized by UGT1A1, UGT2B4, and UGT2B7.</p>Formule :C30H34N2O10Couleur et forme :SolidMasse moléculaire :582.606Sphingomyelin phosphodiesterase
CAS :<p>Sphingomyelin phosphodiesterase, a hydrolase, converts sphingomyelin into phosphocholine and ceramide, affecting cellular processes and cholesterol metabolism.</p>Couleur et forme :SolidDSPE-PEG5000-LTLRWVGLMS
<p>DSPE-PEG5000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 serves as a receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG5000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour SolidAllotetrahydrocortisol
CAS :<p>Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.</p>Formule :C21H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.49Febuxostat n-butyl isomer
CAS :<p>Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Formule :C16H16N2O3SCouleur et forme :SolidMasse moléculaire :316.38α-2,6-Sialyltransferase (Pd26ST)
CAS :<p>Alpha-2,6-Sialyltransferase (Pd26ST) efficiently catalyzes the sialylation of both terminal and internal galactose and N-acetylgalactosamine residues, resulting</p>Couleur et forme :SolidBerninamycin D
CAS :<p>Berninamycin D, a cyclic peptide derived from Streptomyces bernensis through fermentation, is recognized as a fungal metabolite [1].</p>Formule :C45H45N13O13SCouleur et forme :SolidMasse moléculaire :1007.98Ninopterin
CAS :<p>Ninopterin is an experimental antineoplastic and folic acid analog.</p>Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42A32390A
CAS :<p>A32390A, an antibiotic inhibitor, shows antimicrobial activity against gram-positive bacteria and fungi.</p>Formule :C18H24N2O8Couleur et forme :SolidMasse moléculaire :396.39Nap-FF
CAS :<p>Nap-FF is a cell-penetrating dipeptide used in the preparation of hydrogel chemical sensors and for research in targeted drug delivery.</p>Formule :C30H28N2O4Couleur et forme :SolidMasse moléculaire :480.554NPE-caged-proton
CAS :<p>Generates rapid acidifications down to pH 2</p>Formule :C8H9NNaO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :270.229-PAHPA
CAS :<p>9-PAHPA, a fatty acid ester of hydroxy fatty acid (FAHFA), belongs to a recently identified family of endogenous lipids known for their antidiabetic and anti-</p>Formule :C32H62O4Couleur et forme :SolidMasse moléculaire :510.83Leucine dehydrogenase
CAS :<p>Leucine dehydrogenase from Bacillus spheroides oxidizes/reduces branched-chain amino acids and their keto analogs.</p>Couleur et forme :SolidButyrolactone II
CAS :<p>Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6.</p>Formule :C19H16O7Couleur et forme :SolidMasse moléculaire :356.33DSPE-PEG1000-APRPG
<p>DSPE-PEG1000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is applicable for drug delivery.</p>Couleur et forme :Odour SolidH-Gly-Pro-Gly-NH2
CAS :<p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>Formule :C9H16N4O3Couleur et forme :SolidMasse moléculaire :228.25Febuxostat isopropyl isomer
CAS :<p>Febuxostat isopropyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Formule :C15H14N2O3SCouleur et forme :SolidMasse moléculaire :302.352-Aminoflubendazole
CAS :<p>2-Aminoflubendazole, a metabolite of benzimidazoles (BZ), belongs to a class of drugs effective against fungi, protozoa, and helminths.</p>Formule :C14H10FN3OCouleur et forme :SolidMasse moléculaire :255.25CM121
CAS :<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Formule :C24H17FN4O3SCouleur et forme :SolidMasse moléculaire :460.48α-Glucosidase-IN-85
<p>α-Glucosidase-IN-85 (Compound 8D1) functions as an inhibitor of α-Glucosidase, with an IC50 of 5.43 μM. This compound is useful for research related to type 2 diabetes.</p>Couleur et forme :Odour Solid
