Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(165 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8628 produits trouvés pour "Métabolisme"
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γ-Glu-Gly TFA
<p>γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid).</p>Couleur et forme :Liquid(1S)-Calcitriol
CAS :<p>(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.</p>Formule :C27H44O3Couleur et forme :SolidMasse moléculaire :416.646CMI977
CAS :<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Formule :C16H19FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.33Cellohexaose
CAS :<p>Cellohexaose, a cellulose-derived polymer, comprises at least two β(1-4) linked D-glucose units.</p>Formule :C36H62O31Couleur et forme :SolidMasse moléculaire :990.86ML171
CAS :<p>Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C14H11NOSCouleur et forme :Mustard-Colored PowderMasse moléculaire :241.3BChE-IN-36
<p>hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.</p>Couleur et forme :Odour SolidRostratin C
CAS :<p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>Formule :C20H24N2O8S2Couleur et forme :SolidMasse moléculaire :484.54VDR agonist 2
<p>VDR agonist 2 (compound 16i), a vitamin D receptor (VDR) agonist, effectively inhibits TGF-β1-induced hepatic stellate cell (HSC) activation, demonstrating</p>Formule :C20H21F3O3Couleur et forme :SolidMasse moléculaire :366.37DSPE-PEG5000-SP94
<p>DSPE-PEG5000-SP94 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (SP94). SP94 demonstrates specific binding affinity to hepatocellular carcinoma (HCC) cells.</p>Couleur et forme :Odour SolidTrimipramine N-oxide
CAS :<p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>Formule :C20H26N2OCouleur et forme :SolidMasse moléculaire :310.43M3/PDE4 modulator-1
<p>M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.</p>Formule :C38H41Cl2N3O8SCouleur et forme :SolidMasse moléculaire :770.72DSPE-PEG2000-CGKRK
<p>DSPE-PEG2000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is suitable for use in drug delivery.</p>Couleur et forme :Odour SolidPectin
CAS :<p>Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.</p>Couleur et forme :SolidTacalcitol monohydrate
CAS :<p>Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.</p>Formule :C27H46O4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :434.65Carbazeran citrate
CAS :aldehyde oxidase (AO) substrateFormule :C24H32N4O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :552.53SF2312 ammonium
<p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>Formule :C4H11N2O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :214.11Phenacaine
CAS :<p>Phenacaine, also known as Holocaine, is a local anesthetic that blocks certain Ca 2+ enzymes in red blood cells, brain, and heart.</p>Formule :C18H22N2O2Couleur et forme :SolidMasse moléculaire :298.38GP4G
CAS :<p>GP4G, from Artemia salina cysts, regulates epithelial cells & hair growth.</p>Formule :C20H28N10O21P4Couleur et forme :SolidMasse moléculaire :868.396β-hydroxy Eplerenone
CAS :<p>6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP</p>Formule :C24H30O7Couleur et forme :SolidMasse moléculaire :430.497γ-glutamyltransferase
CAS :<p>γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.</p>Couleur et forme :SolidSX29
<p>SX29 is a non-competitive α-glucosidase inhibitor with oral activity, exhibiting an IC50 of 2.12 μM. It possesses hypoglycemic properties; oral administration of SX29 reduces blood glucose levels and enhances glucose tolerance in diabetic mice.</p>Couleur et forme :Odour Solid(±)-Equol 4'-sulfate (sodium salt)
CAS :(±)-Equol 4’-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol .[1] It has been used as a standard for theFormule :C15H13NaO6SCouleur et forme :SolidMasse moléculaire :344.32WXC-25
<p>WXC-25 is an α-glucosidase inhibitor with an IC50 value of 2.02 μM.</p>Couleur et forme :Odour SolidXanthine oxidase-IN-16
<p>Xanthine oxidase-IN-16 is an effective orally active inhibitor of xanthine oxidase (XO), demonstrating significant therapeutic efficacy in rats with hyperuricemia and an IC50 of 102 nM.</p>Couleur et forme :Odour Solidα-Glucosidase-IN-74
<p>α-Glucosidase-IN-74, a nicotinamide-thiazole derivative, functions as an α-glucosidase (α-glucosidase) inhibitor. It demonstrates antidiabetic activity by reducing blood glucose and triglyceride levels in Streptozotocin-induced diabetic animals.</p>Couleur et forme :Odour SolidDSPE-PEG5000-K237
<p>DSPE-PEG5000-K237 is a PEG compound composed of DSPE and the KDR-targeting peptide (K237). K237 effectively disrupts the interaction between VEGF and KDR receptors, yielding significant biological effects, such as inhibiting angiogenesis and tumor growth. DSPE-PEG5000-K237 is applicable for drug delivery.</p>Couleur et forme :Odour Solid6-Azathymine acid
CAS :<p>6-Azathymine is a metabolite of Pymetrozine, an insecticide targeting aphids and whiteflies by disrupting feeding.</p>Formule :C4H3N3O4Couleur et forme :SolidMasse moléculaire :157.08DSPE-PEG1000-NYZL1
<p>DSPE-PEG1000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to selectively bind to bladder cancer tissues and cells. This compound is applicable for drug delivery purposes.</p>Couleur et forme :Odour SolidTDO-IN-2
<p>TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 μM. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.</p>Formule :C20H15N3O3Couleur et forme :SolidMasse moléculaire :345.11134SPL-334
CAS :<p>SPL-334 is an inhibitor of S-nitrosoglutathione reductase.</p>Formule :C22H15N3O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.50Ilexsaponin B2
CAS :<p>Ilexsaponin B2 is a natural product for research related to life sciences. The catalog number is TJS0502 and the CAS number is 108906-69-0.</p>Formule :C47H76O17Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :913.1BSO-07
<p>BSO-07 is a ROS/JNK activator that exhibits potent anti-cancer properties, demonstrated by an IC50 of 24.81 μM in human breast cancer (BC) cells. The mechanism of action for BSO-07 involves JNK activation and the promotion of increased ROS levels, which lead to the induction of apoptosis (Apoptosis) and tumorigenic apoptosis. This includes enhanced expression of apoptosis-related proteins such as PARP, Bax, phosphorylated p53, ATF4, and CHOP, along with a reduction in the levels of anti-apoptotic proteins (e.g., Bcl-2, Bcl-xL, and Survivin). BSO-07 holds promise for research in the field of breast cancer.</p>Couleur et forme :Odour Solid1-Naphthyl 3,5-dinitrobenzoate
CAS :<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Formule :C17H10N2O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :338.27Arofylline
CAS :<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Formule :C14H13ClN4O2Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :304.73Cystocholic acid
CAS :<p>Cystocholic acid is a metabolite of bile acids, possessing antimicrobial potential.</p>Formule :C27H45NO7Couleur et forme :SolidMasse moléculaire :495.65hBChE-IN-3
<p>hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.</p>Couleur et forme :Odour SolidDSPE-PEG5000-NGR
<p>DSPE-PEG5000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide has the capability to target tumor vasculature antigen CD13. DSPE-PEG5000-NGR is applicable in drug delivery.</p>Couleur et forme :Odour SolidNIM811
CAS :<p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>Formule :C62H111N11O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1202.635C14-490
CAS :<p>C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).</p>Formule :C86H177N5O7Couleur et forme :SolidMasse moléculaire :1393.35PK-10
<p>PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains.</p>Formule :C35H36F3N5OCouleur et forme :SolidMasse moléculaire :599.69Leucylproline
CAS :Leucylproline is a peptide that proteolytic breakdown product by larger proteins.Formule :C11H20N2O3Couleur et forme :SolidMasse moléculaire :228.298-Demethyl Ivabradine
CAS :<p>8-Demethyl Ivabradine, a metabolite of Ivabradine, is an oral HCN channel blocker.</p>Formule :C26H34N2O5Couleur et forme :SolidMasse moléculaire :454.567Sofosbuvir impurity E
<p>Sofosbuvir impurity E, a less active byproduct, inhibits HCV RNA replication with potent anti-HCV effects.</p>Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45DSPE-PEG5000-T7
<p>DSPE-PEG5000-T7 is a PEG-based compound composed of DSPE and transferrin receptor peptide (T7). T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG5000-T7 is applicable in drug delivery.</p>Couleur et forme :Odour SolidS32826
CAS :<p>S32826, a potent autotaxin inhibitor with an IC50 of 8.8 nM, blocks LPA release and targets α, β, γ isoforms.</p>Formule :C21H36NO4PCouleur et forme :SolidMasse moléculaire :397.496GLUT1-IN-1
<p>GLUT1-IN-1 inhibits GLUT1; cytotoxic to HeLa, A549, HepG2 (IC50: 5.49, 11.14, 8.73 μM); potential in PDT and cancer research.</p>Formule :C25H31BF2I2N6O7Couleur et forme :SolidMasse moléculaire :830.17L-Glutamic acid ammonium
CAS :<p>L-Glutamic acid ammonium is an excitatory neurotransmitter.</p>Formule :C5H12N2O4Couleur et forme :SolidMasse moléculaire :164.16DSPE-PEG2000-ESBP
<p>DSPE-PEG2000-ESBP is a PEGylated compound composed of DSPE and E-selectin binding peptide (ESBP). As a tumor-targeting peptide, ESBP can specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Couleur et forme :Odour Solid(±)10(11)-EpDPA
CAS :<p>Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495Netupitant metabolite Netupitant N-oxide
CAS :<p>Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.</p>Formule :C30H32F6N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.59
