Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(75 produits)
- CETP(20 produits)
- Anhydrase carbonique(188 produits)
- Caséine Kinase(137 produits)
- DHFR(34 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(296 produits)
- FAAH(65 produits)
- FXR(59 produits)
- Facteur Xa(85 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(221 produits)
- GR(3 produits)
- GSNOR(4 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(35 produits)
- IDO(84 produits)
- LDL(8 produits)
- Lipase(105 produits)
- Lipides(62 produits)
- Lipoxygénase(133 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(169 produits)
- Phospholipase(82 produits)
- ROR(45 produits)
- Récepteur de rétinoïdes(28 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(29 produits)
- Tansporteur(46 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9132 produits trouvés pour "Métabolisme"
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MGAT2-IN-2
CAS :MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) (IC50 of 3.4 nM).Formule :C26H21F5N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.53L-CCG-lll
CAS :inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.Formule :C6H9NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :159.14GTPγS tetralithium
CAS :GTPγS tetralithium (Guanosine 5'-[γ-thio]triphosphate tetralithium) is a G-protein activator and a non-hydrolyzable GTP analog.Formule :C10H12Li4N5O13P3SDegré de pureté :75%Couleur et forme :SolidMasse moléculaire :562.98S-Benzylglutathione
CAS :S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.Formule :C17H23N3O6SCouleur et forme :SolidMasse moléculaire :397.457,12-Diketolithocholic Acid
CAS :<p>7,12-Diketolithocholic acid, a bile acid, exhibits elevated plasma levels in patients experiencing cholestasis.</p>Formule :C24H36O5Couleur et forme :SolidMasse moléculaire :404.54N-Formyl-L-histidine
CAS :N-Formyl-L-histidine is a competitive inhibitor of L-histidine deaminase (Ki = 4.26 mM) and also binds to histidine-tRNA synthetase (Ki = 4.6 μM).Formule :C7H9N3O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :183.16Gentisuric acid
CAS :<p>Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]</p>Formule :C9H9NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :211.17E-5324
CAS :E-5324 is potent cholesterol acyltransferase (ACAT) inhibitor (IC50s: 44 to 190 nM).Formule :C26H34N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.5713,14-dihydro-15(R)-Prostaglandin E1
CAS :<p>13,14-Dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1) is an analog of 13,14-dihydro-PGE1 characterized by its R-configured hydroxyl group at the C-15 position [1].</p>Formule :C20H36O5Couleur et forme :SolidMasse moléculaire :356.503CYP17-IN-1
CAS :<p>CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.</p>Formule :C18H17FN2SDegré de pureté :99.14% - 99.83%Couleur et forme :SolidMasse moléculaire :312.4GCase modulator-1
CAS :<p>GCase Modulator-1 (Compound 9g), a quinazoline derivative, functions as a glucosidase modulator with an AC50 value of 2.23 µM [1].</p>Formule :C22H18N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.41B 581
CAS :B 581 is an inhibitor that specifically blocks farnesylated.Formule :C22H38N4O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.69AMC Arachidonoyl Amide
CAS :<p>Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates the rapid and efficient assessment of FAAH activity through the utilization of either a standard cuvette or a microplate fluorometer.</p>Formule :C30H39NO3Couleur et forme :SolidMasse moléculaire :461.6PDP-EA
CAS :<p>PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.</p>Formule :C25H43NO3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :405.61FAAH/cPLA2α-IN-1
CAS :FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (Formule :C19H26N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.43LY-338979
CAS :LY-338979 is an impurity of pemetrexedone.Formule :C20H21N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.411,2-Dipalmitoyl-3-Myristoyl-rac-glycerol
CAS :1,2-Dipalmitoyl-3-myristoyl-rac-glycerol, a triacylglycerol, incorporates palmitic acid at the sn-1 and sn-2 positions, along with myristic acid at the sn-3 position, and is identified in bovine milk fat.Formule :C49H94O6Couleur et forme :SolidMasse moléculaire :779.27ICMT-IN-49
CAS :ICMT-IN-49 (Compound 2) acts as an ICMT inhibitor with an IC50 value of 0.12 μM [1].Formule :C27H31NO3Couleur et forme :SolidMasse moléculaire :417.54LB-60-OF61
CAS :<p>LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.</p>Formule :C29H30N6O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :494.59Autotaxin-IN-5
CAS :Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.Formule :C30H29N9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.61Flucythrinate
CAS :Flucythrinate is an insecticide.Formule :C26H23F2NO4Couleur et forme :Viscous Liquid SolidMasse moléculaire :451.46Glucosamine Cholesterol
CAS :Glucosamine Cholesterol, also known as N-Cholesteryl succinyl glucosamine, is a lipid conjugate derived from glucosamine. It plays a crucial role in the development of lipid nanoparticles (LNPs) [1].Formule :C37H61NO8Couleur et forme :SolidMasse moléculaire :647.88Anticancer agent 144
CAS :Compound 144 (also known as Anticancer Agent 144) is a potent inhibitor of both PTPN2 and PTP1B, exhibiting IC50 values of less than 2.5 nM, making it suitableFormule :C19H15BrF2N3O6PS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.34Ilepatril
CAS :Ilepatril, also known as AVE-7688, is a vasopeptidase inhibitor for the treatment of hypertension.Formule :C22H28N2O5SCouleur et forme :SolidMasse moléculaire :432.53Pentadecanoyl ethanolamide
CAS :<p>Pentadecanoyl ethanolamide, a derivative of the endogenous lipid amides (N-acylethanolamines), demonstrates anticonvulsant efficacy in electroshock-induced seizures in mice, exhibiting minimal toxicity [1].</p>Formule :C17H35NO2Couleur et forme :SolidMasse moléculaire :285.472ICMT-IN-6
CAS :<p>ICMT-IN-6 (compound 29) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an inhibitory concentration 50 (IC50) value of</p>Formule :C23H31NO2Couleur et forme :SolidMasse moléculaire :353.5YG1702
CAS :YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Formule :C23H30N2O7SCouleur et forme :SolidMasse moléculaire :478.56Ganciclovir triphosphate
CAS :Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.Formule :C9H16N5O13P3Couleur et forme :SolidMasse moléculaire :495.17AR453588
CAS :AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.Formule :C25H25N7O2S2Couleur et forme :SolidMasse moléculaire :519.64UK-157147
CAS :<p>UK-157147 is a substrate for UGT1A1(Km: 105 μM).</p>Formule :C23H24N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.51Siguazodan
CAS :Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.Formule :C14H16N6ODegré de pureté :99.62% - 99.87%Couleur et forme :SolidMasse moléculaire :284.325α-Androstan-3β-ol
CAS :5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.Formule :C19H32OCouleur et forme :SolidMasse moléculaire :276.469-OxoODE
CAS :9-OxoODE, formed through the oxidation of the allylic hydroxyl group in both 9(S)-HODE and 9(R)-HODE, is present in rabbit reticulocyte plasma and mitochondrial membranes as both 9- and 13-oxoODEs, constituting approximately 2% of the total linoleate residues. The majority of these oxidized linoleate residues are esterified to membrane lipids.Formule :C18H30O3Couleur et forme :SolidMasse moléculaire :294.42-Myristyldistearin
CAS :2-Myristyldistearin (SMS), a triacylglycerol comprising myristic acid and stearic acid [1], showcases its intricate structural composition.Formule :C53H102O6Couleur et forme :SolidMasse moléculaire :835.37DOG-IM4
CAS :DOG-IM4 is a chemical compound instrumental in synthesizing nanoparticles for delivering antigen-encoding nucleic acids, targeting a broad range of conditions including autoimmune diseases, rare blood or metabolic disorders, allergies, cancer, and infectious diseases [1].Formule :C51H95N3O7Couleur et forme :SolidMasse moléculaire :862.32RORγt modulator 4
CAS :RORγt modulator 4 is a RORγt modulator that regulates IL-17A production activity in cells derived from mouse spleen.Formule :C26H27N3O4SCouleur et forme :SolidMasse moléculaire :477.58BBT
CAS :BBT has anti-hyperglycemic activity, protecting beta cells from cytokine or streptozotocin-induced cell death, and restoring beta cell function.Formule :C18H12BrNO2SDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :386.26ICMT-IN-43
CAS :<p>ICMT-IN-43 (compound 22) acts as a potent inhibitor of the enzyme ICMT, exhibiting an inhibitory concentration (IC50) value of 0.04 μM [1].</p>Formule :C23H31NOCouleur et forme :SolidMasse moléculaire :337.54-Hydroxyphenylglyoxylic Acid
CAS :4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1).Formule :C8H6O4Couleur et forme :SolidMasse moléculaire :166.13EMD638683 R-Form
CAS :EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.Formule :C18H18F2N2O4Couleur et forme :SolidMasse moléculaire :364.34Me-Indoxam
CAS :Me-Indoxam is an inhibitor of sPLA2. It has no effect on arachidonic acid release and platelet activating factor synthesis.Formule :C26H22N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.46GSK-8062
CAS :GSK-8062 is an agonist of farnesoid X receptor (FXR).Formule :C30H23Cl2NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.413-Oxo-5β-cholanoic acid
CAS :3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directlyFormule :C24H38O3Degré de pureté :98.01% - 99.86%Couleur et forme :SolidMasse moléculaire :374.56IDO-IN-9
CAS :IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell).Formule :C13H13BrFN7O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :446.251-Stearoyl-3-Linoleoyl-rac-glycerol
CAS :1-Stearoyl-3-linoleoyl-rac-glycerol, a diacylglycerol, incorporates stearic acid at the sn-1 position and linoleic acid at the sn-3 position. Its levels rise in a time-dependent manner throughout the ripening process of dry-cured sausages.Formule :C39H72O5Couleur et forme :SolidMasse moléculaire :620.991,2,3-Tri-γ-Linolenoyl Glycerol
CAS :1,2,3-Tri-γ-linolenoyl glycerol, a polyunsaturated triacylglycerol featuring γ-linolenoyl side chains at the C-1, C-2, and C-3 positions, occurs in multiple plant species such as blackcurrant, redcurrant, and borage.Formule :C57H92O6Couleur et forme :SolidMasse moléculaire :873.40GW-6604
CAS :<p>GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.</p>Formule :C19H14N4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :298.34Adibendan
CAS :<p>Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.</p>Formule :C16H14N4ODegré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :278.316β-hydroxy Testosterone
CAS :6β-hydroxy Testosterone （4-Androsten-6β,17β-diol-3-one） is a 17β-hydroxy steroid, an androgen and endogenous metabolite.Formule :C19H28O3Couleur et forme :SoildMasse moléculaire :304.42FXR antagonist 1
CAS :"Oral FXR antagonist 1 selectively blocks intestinal FXR, with IC50 of 2.1 μM, aiding in NASH research by improving liver health."Formule :C36H59NO5Couleur et forme :SolidMasse moléculaire :585.86
