Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(67 produits)
- CETP(18 produits)
- Anhydrase carbonique(178 produits)
- Caséine Kinase(130 produits)
- DHFR(33 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(271 produits)
- FAAH(64 produits)
- FXR(58 produits)
- Facteur Xa(80 produits)
- Synthase des acides gras(33 produits)
- Ferroptose(215 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(54 produits)
- Prolyl-Hydroxylase de HIF/HIF(142 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(30 produits)
- IDO(82 produits)
- LDL(8 produits)
- Lipase(98 produits)
- Lipides(58 produits)
- Lipoxygénase(124 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(36 produits)
- P450(6 produits)
- PAI-1(25 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(165 produits)
- Phospholipase(82 produits)
- ROR(42 produits)
- Récepteur de rétinoïdes(29 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(42 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
8628 produits trouvés pour "Métabolisme"
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H-Met-Val-OH
CAS :<p>H-Met-Val-OH is a dipeptide inhibiting FMO1 and FMO3 and promoting neurite outgrowth, relevant for neuroregenerative and enzymatic modulation studies.</p>Formule :C10H20N2O3SCouleur et forme :SolidMasse moléculaire :248.34Bromacil
CAS :<p>Bromacil, a substituted uracil herbicide used worldwide, is not readily biodegradable and therefore has consequences to the environment.</p>Formule :C9H13BrN2O2Couleur et forme :SolidMasse moléculaire :261.127-hydroxy Coumarin sulfate (potassium salt)
CAS :<p>7-hydroxy Coumarin sulfate, a phase II coumarin metabolite, aids as an internal standard for GC/LC-MS metabolic analyses.</p>Formule :C9H5KO6SCouleur et forme :SolidMasse moléculaire :280.3DSPE-PEG5000-LTLRWVGLMS
<p>DSPE-PEG5000-LTLRWVGLMS is a PEG compound composed of DSPE and the decapeptide (LTLRWVGLMS). Chondroitin sulfate proteoglycan NG2 serves as a receptor for LLRWVGLMS. LLRWVGLMS demonstrates homing to pericytes associated with tumor vasculature. DSPE-PEG5000-LTLRWVGLMS can be utilized for drug delivery.</p>Couleur et forme :Odour Solid(5S)-Neosamine C
CAS :<p>(5S)-Neosamine C, an aminocyclic alcohol antibiotic derived from microbial secondary metabolites, possesses a cyclized structure and is utilized in the biosynthesis of Neomycins.</p>Formule :C6H14N2O4Couleur et forme :SolidMasse moléculaire :178.19L-Hisidine monohydrocholoride
CAS :<p>L-Hisidine is an essential amino acid for infants and acts as an inhibitor of mitochondrial glutamine transport.</p>Formule :C6H10ClN3O2Couleur et forme :SolidMasse moléculaire :191.62Fibrostatin C
CAS :<p>Fibrostatin C is an inhibitor of prolyl 4-hydroxylase. It is produced by Streptomyces catenulae subsp.</p>Formule :C18H19NO8SCouleur et forme :SolidMasse moléculaire :409.41CIGB-300
CAS :<p>CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.</p>Formule :C127H215N53O30S3Couleur et forme :SolidMasse moléculaire :3060.6Nor-Acetildenafil
CAS :<p>Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor.</p>Formule :C24H32N6O3Couleur et forme :SolidMasse moléculaire :452.555(S)-HETE
CAS :<p>5(S)-HETE, an endogenous metabolite found in the blood, is utilized in researching Rheumatoid Arthritis, Rhinitis, and Asthma [1] [2].</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47PTP1B-IN-14
CAS :<p>PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50)</p>Formule :C27H19N5O3S4Couleur et forme :SolidMasse moléculaire :589.73DSPE-PEG2000-Azide ammonium
CAS :<p>DSPE-PEG2000-Azide ammonium is a lipid-based azide compound used in forming micelles for nanoparticle drug delivery. It serves as a click chemistry reagent and includes an azide group that reacts with molecules containing an alkyne group through a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc). Additionally, it can engage in a strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.</p>Couleur et forme :SolidIRC-083864
CAS :<p>IRC-083864 is a novel bis quinone CDC25 phosphatase active inhibitor against human cancer cells.</p>Formule :C28H25F2N5O5SCouleur et forme :SolidMasse moléculaire :581.59PDE5-IN-11
<p>PDE5-IN-11 is a potent PDE5 inhibitor, exhibiting an IC50 of 40 nM, and also displays inhibitory activity against PDE4 and PDE6 with IC50 values of 1.78 μM and</p>Couleur et forme :Odour Solid1-Palmitoyl-2-linoleoyl PE
CAS :Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.Formule :C39H74NO8PCouleur et forme :SolidMasse moléculaire :715.994Muvalaplin tetrahydrochloride
CAS :<p>Muvalaplin tetrahydrochloride (LY3473329) is an orally active lipoprotein (a)Lp(a) agent currently under investigation. Research on the oral formulation of Muvalaplin tetrahydrochloride is ongoing.</p>Formule :C42H58Cl4N4O6Couleur et forme :SolidMasse moléculaire :856.75Ionizable Lipid 4
CAS :<p>Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.</p>Formule :C48H85NO7Couleur et forme :SolidMasse moléculaire :788.19Daprodustat
CAS :Daprodustat (GSK1278863) is a HIF-prolyl hydroxylase inhibitor.Formule :C19H27N3O6Degré de pureté :97% - 99.82%Couleur et forme :SolidMasse moléculaire :393.432,7"-Phloroglucinol-6,6'-bieckol
CAS :<p>2,7"-Phloroglucinol-6,6'-bieckol serves as an effective oral dual α-amylase/α-glucosidase inhibitor, demonstrating IC 50 concentrations of 6.94 μM and 23.35 μM, respectively. This compound is beneficial in mitigating postprandial hyperglycemia among diabetic mice and is applicable in diabetes research [1].</p>Formule :C48H30O23Couleur et forme :SolidMasse moléculaire :974.744-hydroxy Nonenal Mercapturic Acid
CAS :Peroxidation of ω-6 PUFAs produces 4-HNE, which is rapidly cleared and excreted, mostly as urine metabolites, within 48h in rats.Formule :C14H25NO5SCouleur et forme :SolidMasse moléculaire :319.42Geranyl pyrophosphate triammonium
CAS :<p>Geranyl pyrophosphate, an intermediary for making cholesterol, terpenes, and others, forms from dimethylallyl and isopentenyl pyrophosphates.</p>Formule :C10H29N3O7P2Couleur et forme :SolidMasse moléculaire :365.304Creatine riboside
CAS :<p>Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.</p>Formule :C9H17N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :263.25IDO-IN-15
CAS :<p>IDO-IN-15 is an IDO1 inhibitor ( IC 50 < 0.51 nM).</p>Formule :C29H39N5O4Couleur et forme :SolidMasse moléculaire :521.662Febuxostat sec-butoxy acid
CAS :<p>Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Formule :C16H16N2O3SCouleur et forme :SolidMasse moléculaire :316.372,4-Dimethylquinoline
CAS :<p>2,4-Dimethylquinoline is a potential CYP1A2 inhibitor , and it also exhibits weak inhibitory activity against CYP2A5, CYP2A6, and CYP2B6.</p>Formule :C11H11NDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :157.21Vitamin K5
CAS :<p>Vitamin K5, a photosensitizer & antimicrobial, inhibits PKM2, PKM1 & PKL, induces apoptosis in colon cells, and preserves food & medicine.</p>Formule :C11H11NOCouleur et forme :SolidMasse moléculaire :173.21NGR peptide
CAS :<p>Cell-penetrating peptide</p>Formule :C20H36N10O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.691-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS :<p>Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.</p>Formule :C40H80NO8PDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :734.04Vardenafil dihydrochloride
CAS :<p>Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.</p>Formule :C23H34Cl2N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.52SY-640
CAS :<p>SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.</p>Formule :C11H13NO3Degré de pureté :99.51% - 99.66%Couleur et forme :SolidMasse moléculaire :207.23Prolylglutamic acid
CAS :<p>Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.</p>Formule :C10H16N2O5Couleur et forme :SolidMasse moléculaire :244.24SHO1122147
<p>SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 μM). It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH).</p>Formule :C17H11ClN4O2Couleur et forme :SolidMasse moléculaire :338.748Zaragozic acid D
CAS :<p>Zaragozic acid D inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Formule :C34H46O14Couleur et forme :SolidMasse moléculaire :678.721-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS :1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.Formule :C12H14N2O4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :250.25MS-PPOH
CAS :<p>MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectively</p>Formule :C16H21NO4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :323.41DSPE-PEG2000-LyP-1
<p>DSPE-PEG2000-LyP-1 is a PEG compound composed of DSPE and a nine-residue peptide (LyP-1). LyP-1 specifically targets tumor-associated lymphatic vessels and macrophages.</p>Couleur et forme :Odour Solid9(R)-HODE cholesteryl ester
CAS :<p>9(R)-HODE cholesteryl ester, from atherosclerotic lesions, may form enzymatically or by lipid peroxidation; used as a chiral analysis standard.</p>Formule :C45H76O3Couleur et forme :SolidMasse moléculaire :665.1ENPP3 Inhibitor 1
CAS :ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, exhibiting an IC50 value of 0.15 µM, compared to an IC50 of 41.4 µM for ENPP1. It demonstrates antitumor effects against breast and cervical cancers.Formule :C20H14F3NO5SCouleur et forme :SolidMasse moléculaire :437.39F-14329
CAS :<p>F-14329 is a tetramic acid fungal metabolite [1] .</p>Formule :C21H27NO5Couleur et forme :SolidMasse moléculaire :373.44β-Apooxytetracycline
CAS :<p>β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline.</p>Formule :C22H22N2O8Couleur et forme :SolidMasse moléculaire :442.424Fmoc-Asp-OAll
CAS :<p>Fmoc-Asp-OAll (Fmoc-L-aspartic acid a-allyl ester) is an aspartic acid derivative.</p>Formule :C22H21NO6Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :395.411,2,3,6,7,8-Hexachlorodibenzofuran
CAS :<p>1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.</p>Formule :C12H2Cl6OCouleur et forme :SolidMasse moléculaire :374.86(S)-O-Desmethyl Venlafaxine N-Oxide
CAS :<p>(S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide metabolite of Venlafaxine, an SNRI antidepressant.</p>Formule :C16H25NO3Couleur et forme :SolidMasse moléculaire :279.37L-Lysine, sulfite (2:1)
CAS :<p>L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.</p>Formule :C6H14N2O2H2O3SCouleur et forme :SolidMasse moléculaire :187.232-Hydroxy atorvastatin lactone
CAS :<p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>Formule :C33H33FN2O5Couleur et forme :SolidMasse moléculaire :556.62Pyrrophenone
CAS :<p>Pyrrophenone selectively and reversibly inhibits cPLA2 (IC50=4.2 nM), blocks AA, PGE2, and LTC4 production in cells, and is less effective on other PLA2s.</p>Formule :C49H37F2N3O5S2Couleur et forme :SolidMasse moléculaire :849.97DSPE-PEG
CAS :<p>DSPE-PEG: a phospholipid-polymer for stable, efficient drug delivery with longer circulation.</p>Formule :C45H90NO10PCouleur et forme :SolidMasse moléculaire :835.63024Dimethylaminomicheliolide HCl
CAS :<p>Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate</p>Formule :C17H28ClNO3Degré de pureté :99.55%Couleur et forme :SoildMasse moléculaire :329.86Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
CAS :<p>Vildagliptin's main human metabolite inhibits DPP-4 (IC50: 477 μM) in Caco-2 cells, formed by cyano group hydrolysis.</p>Formule :C19H27F3N2O6Couleur et forme :SolidMasse moléculaire :436.42811β-HSD1 inibitor 17
CAS :<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Formule :C22H20F3N3O2SDegré de pureté :99.26% - 99.72%Couleur et forme :SoildMasse moléculaire :447.47
