Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(227 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(134 produits)
- MAO(85 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(85 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(17 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9188 produits trouvés pour "Métabolisme"
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Pregnant mare serum gonadotropin
CAS :Pregnant mare serum gonadotropin (PMSG) functions as a gonadotropin that enhances follicular development and ovulation in animals. This compound operates by modulating blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. Commonly employed in livestock to boost reproductive efficiency, PMSG is also valuable for research focused on estrous cycle regulation.Couleur et forme :SolidSorbitol-6-phosphate 2-dehydrogenase
CAS :Sorbitol-6-phosphate 2-dehydrogenase, a dehydrogenase enzyme produced by Escherichia coli, catalyzes the interconversion of D-sorbitol 6-phosphate and D-fructose 6-phosphate. The enzyme oxidizes D-sorbitol 6-phosphate at a rate ten times faster than it reduces D-fructose 6-phosphate, playing a role in various cellular processes.Couleur et forme :Solid12α-Hydroxysteroid dehydrogenase
CAS :12α-Hydroxysteroid dehydrogenase, an NAD-dependent enzyme expressed in Bacillus sphaericus, actively processes both free and conjugated bile salts. It is utilized to determine the levels of 12α-hydroxy bile acids in serum.Couleur et forme :SolidMethyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate
CAS :Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.Formule :C25H40O4Couleur et forme :SolidMasse moléculaire :404.58MPC-IN-1
MPC-IN-1 (compound 4i), a derivative of UK-5099, is a cyanocinnamate-based inhibitor of the mitochondrial pyruvate transporter (MPC). This compound selectively fosters the development of hair follicle stem cells while not impacting normal cells. It enhances cellular lactate production and has shown significant hair growth promotion in mice, suggesting its potential use in combating hair loss.Formule :C18H13N3O2Couleur et forme :SolidMasse moléculaire :303.31N-Benzoyl-L-Leucine
CAS :N-Benzoyl-L-Leucine is a leucine derivative exhibiting antibacterial activity against Staphylococcus aureus.Formule :C13H17NO3Degré de pureté :99.60%Couleur et forme :SoildMasse moléculaire :235.28Dazonone
CAS :Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.Formule :C11H10ClN3ODegré de pureté :99.54% - 99.73%Couleur et forme :SolidMasse moléculaire :235.67Ref: TM-T9871
1mg73,00€1mL*10mM (DMSO)131,00€5mg149,00€10mg213,00€25mg319,00€50mg450,00€100mg605,00€200mg802,00€Cysteinylglycine acetate
Cysteinylglycine acetate (Cys-Gly Acetate) is an acetate salt of Cysteinylglycine.
Formule :C7H14N2O5SDegré de pureté :99.49%Couleur et forme :SoildMasse moléculaire :238.26Toddacoumalone
CAS :Toddacoumalone, a natural PDE4 inhibitor, shows promise for inflammatory disease research.Formule :C31H31NO6Couleur et forme :SolidMasse moléculaire :513.58DP-1 hydrochloride
CAS :DP-1 hydrochloride is a degradation product of SDC-TRAP-0063, a fragment of Ganetespib, a heat shock protein 90 (HSP90) inhibitor with antitumor activity.Formule :C26H32ClN5O3Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :498.02Ref: TM-T38961L
1mg101,00€5mg240,00€1mL*10mM (DMSO)265,00€10mg358,00€25mg558,00€50mg797,00€100mg1.103,00€200mg1.483,00€7-Hydroxymethotrexate
CAS :7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.Formule :C20H22N8O6Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :470.44human TDO2-IN-1
Human TDO2-IN-1 (Cpd-2) is a potent inhibitor of human TDO2, with an IC50 of 14.8 nM. It plays a significant role in studies related to metabolism, inflammation, and tumor immune surveillance.Formule :C30H36N4O5Couleur et forme :SolidMasse moléculaire :532.631(±)18-HETE
CAS :(±)18-HETE (18-Hydroxyeicosatetraenoic acid) is an arachidonic acid metabolite with a hydroxyl group on carbon 18, catalyzed by cytochrome P-450.Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47Adrenergic Receptor-Targeted Compound Library
A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;Couleur et forme :Odour SolidRef: TM-L2700
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderhCAII-IN-8
CAS :Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Formule :C15H16N2O5SDegré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :336.36Ref: TM-T67774
5mg42,00€1mL*10mM (DMSO)52,00€10mg64,00€25mg116,00€50mg167,00€100mg241,00€200mg339,00€ONO-8430506
CAS :ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.Formule :C27H28FN3O3Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :461.53Ref: TM-T38759
1mg103,00€5mg244,00€1mL*10mM (DMSO)271,00€10mg338,00€25mg510,00€50mg687,00€100mg919,00€Anti-Cancer Metabolism Compound Library
A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCSCouleur et forme :Odour SolidRef: TM-L2130
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderMetabolism Compound Library
A unique collection of xnum metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening.Couleur et forme :LiquidRef: TM-L2560
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderAsundexian
CAS :Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formule :C26H21ClF4N6O4Degré de pureté :99.89% - 99.90%Couleur et forme :SolidMasse moléculaire :592.93LDHA-IN-3
CAS :LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formule :C13H9F3SeDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :301.17Ref: TM-T39805
1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg371,00€50mg517,00€100mg707,00€200mg973,00€SGK1-IN-4
CAS :SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.Formule :C23H21ClFN5O4SDegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :517.96Ref: TM-T9977
1mg105,00€5mg250,00€1mL*10mM (DMSO)301,00€10mg356,00€25mg580,00€50mg782,00€100mg1.044,00€200mg1.404,00€hBChE-IN-3
hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.Couleur et forme :Odour SolidCAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Couleur et forme :Odour Solidβ-Glucosidase
CAS :β-Glucosidase is a glucoside bond hydrolase involved in glucose metabolism and can be used to study diseases caused by abnormal glucose metabolism.Formule :C24H44O12Couleur et forme :SolidMasse moléculaire :524.6Xanthine oxidase-IN-16
Xanthine oxidase-IN-16 is an effective orally active inhibitor of xanthine oxidase (XO), demonstrating significant therapeutic efficacy in rats with hyperuricemia and an IC50 of 102 nM.Couleur et forme :Odour SolidWXC-25
WXC-25 is an α-glucosidase inhibitor with an IC50 value of 2.02 μM.Couleur et forme :Odour Solid1-Naphthyl 3,5-dinitrobenzoate
CAS :1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formule :C17H10N2O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :338.27Ref: TM-T21838
5mg54,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€γ-glutamyltransferase
CAS :γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.Couleur et forme :SolidSX29
SX29 is a non-competitive α-glucosidase inhibitor with oral activity, exhibiting an IC50 of 2.12 μM. It possesses hypoglycemic properties; oral administration of SX29 reduces blood glucose levels and enhances glucose tolerance in diabetic mice.Couleur et forme :Odour Solidα-Glucosidase-IN-74
α-Glucosidase-IN-74, a nicotinamide-thiazole derivative, functions as an α-glucosidase (α-glucosidase) inhibitor. It demonstrates antidiabetic activity by reducing blood glucose and triglyceride levels in Streptozotocin-induced diabetic animals.Couleur et forme :Odour SolidNIM811
CAS :NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formule :C62H111N11O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1202.635DSPE-PEG5000-NGR
DSPE-PEG5000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide has the capability to target tumor vasculature antigen CD13. DSPE-PEG5000-NGR is applicable in drug delivery.
Couleur et forme :Odour SolidPhenacaine
CAS :Phenacaine, also known as Holocaine, is a local anesthetic that blocks certain Ca 2+ enzymes in red blood cells, brain, and heart.Formule :C18H22N2O2Couleur et forme :SolidMasse moléculaire :298.38PK-10
PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains.Formule :C35H36F3N5OCouleur et forme :SolidMasse moléculaire :599.69Leucylproline
CAS :Leucylproline is a peptide that proteolytic breakdown product by larger proteins.Formule :C11H20N2O3Couleur et forme :SolidMasse moléculaire :228.298-Demethyl Ivabradine
CAS :8-Demethyl Ivabradine, a metabolite of Ivabradine, is an oral HCN channel blocker.Formule :C26H34N2O5Couleur et forme :SolidMasse moléculaire :454.567Pectin
CAS :Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.Couleur et forme :SolidTacalcitol monohydrate
CAS :Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.Formule :C27H46O4Degré de pureté :99.284%Couleur et forme :SolidMasse moléculaire :434.65SF2312 ammonium
SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active underFormule :C4H11N2O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :214.11S32826
CAS :S32826, a potent autotaxin inhibitor with an IC50 of 8.8 nM, blocks LPA release and targets α, β, γ isoforms.Formule :C21H36NO4PCouleur et forme :SolidMasse moléculaire :397.496GLUT1-IN-1
GLUT1-IN-1 inhibits GLUT1; cytotoxic to HeLa, A549, HepG2 (IC50: 5.49, 11.14, 8.73 μM); potential in PDT and cancer research.Formule :C25H31BF2I2N6O7Couleur et forme :SolidMasse moléculaire :830.17BChE-IN-36
hBChE-IN-4 (compound 40) serves as an effective activator for hCA and an inhibitor for BChE. It demonstrates affinity for various hCA subtypes with affinity constants (KA) of 266 nM for hCA I, 76.9 nM for hCA II, 918 nM for hCA IV, 893 nM for hCA VB, and 98.0 nM for hCA VII. Inhibition concentrations (IC50) for eeAChE and eqBChE are recorded at 72.1 nM and 4.2 nM, respectively. hBChE-IN-4 is non-cytotoxic and has demonstrated potential cognitive enhancement effects. It holds potential for research in neurodegenerative and other neuropsychiatric disorders.Couleur et forme :Odour Solid(±)10(11)-EpDPA
CAS :Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers.Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495Netupitant metabolite Netupitant N-oxide
CAS :Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.Formule :C30H32F6N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.59ML171
CAS :Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C14H11NOSCouleur et forme :Mustard-Colored PowderMasse moléculaire :241.3VDR agonist 2
VDR agonist 2 (compound 16i), a vitamin D receptor (VDR) agonist, effectively inhibits TGF-β1-induced hepatic stellate cell (HSC) activation, demonstratingFormule :C20H21F3O3Couleur et forme :SolidMasse moléculaire :366.372-Methoxy-4-propylphenol
CAS :2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.
Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22Streptolysin O
CAS :Streptolysin O: lyses cells, cardiotoxic, used for cell permeabilization, has active and inactive states.Degré de pureté :98%Couleur et forme :Solid(1S)-Calcitriol
CAS :(1S)-Calcitriol, a natural 1α,25(OH)2D3 metabolite, regulates VDR actions like keratinocyte growth inhibition.Formule :C27H44O3Couleur et forme :SolidMasse moléculaire :416.646Ribulose, L-
CAS :Ribulose: key in pentose metabolism, aids L-ribose isomerase study, yeast engineering, and chiral compound research.Formule :C5H10O5Couleur et forme :SolidMasse moléculaire :150.13
