Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(63 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(233 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(36 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(134 produits)
- MAO(84 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(84 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(17 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9198 produits trouvés pour "Métabolisme"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
3-Chloroiminodibenzyl
CAS :Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C14H12ClNMasse moléculaire :229.7BVT-2733 hydrochloride
CAS :BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Formule :C17H22Cl2N4O3S2Couleur et forme :SolidMasse moléculaire :465.42DJ-53
DJ-53 (compound 68) is an orally active, phenyl-quinoline-based soluble epoxide hydrolase inhibitor.Couleur et forme :Odour SolidcisVH 298
CAS :cisVH 298 is a negative control for VH 298. Exhibits no detectable binding of VHL.Formule :C27H33N5O4SCouleur et forme :SolidMasse moléculaire :523.65Nuclease SM
Nuclease SM is a non-specific nuclease endonuclease predominantly found in Salmonella, categorized as a basic protein. It exhibits non-thermostability and can retain its activity for approximately 24 hours at 25°C.D34-919
CAS :D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.Formule :C22H27N5OSCouleur et forme :SolidMasse moléculaire :409.55Osmanthuside H
CAS :Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.4223,5-Di-tert-butyl-4-hydroxybenzaldehyde
CAS :3,5-Di-tert-butyl-4-hydroxybenzaldehyde is a hindered phenol compound that inhibits NCI tumour cell growth and has potential as an RXR antagonist antioxidant.Formule :C15H22O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :234.33NGR peptide Trifluoroacetate
NGR peptide Trifluoroacetate contains an NGR motif recognized by CD13/APN in tumor neovasculature, used for targeted drug delivery in cancer research.Formule :C22H37F3N10O10S2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :722.72Neotheaflavin
CAS :Neotheaflavin, from black tea, inhibits pancreatic lipase.Formule :C29H24O12Couleur et forme :SolidMasse moléculaire :564.49Bam 12P acetate
Bam 12P acetate is the putative enkephalin precursor in bovine adrenal, pituitary, and hypothalamus.Formule :C64H101N21O18SDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :1484.68Enpp-1-IN-21
CAS :Enpp-1-IN-21 (compound 4g) is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with IC50 values of 0.45 μM for ENPP1 and 0.19 μM for ENPP3.Formule :C21H16F3NO5SCouleur et forme :SolidMasse moléculaire :451.4216α-Hydroxyetiocholanolone
CAS :16α-Hydroxyetiocholanolone is a metabolite of 16α-hydroxydehydroisoandrosterone (16α-DHEA) and androstenedione.1,2Formule :C19H30O3Couleur et forme :SolidMasse moléculaire :306.446KAT8-IN-1
CAS :Compound 605-62-9, with CAS No. 605-62-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 605-62-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C10H7NO3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :189.17Glisoprenin D
CAS :Glisoprenin D is a useful organic compound for research related to life sciences. The catalog number is T125390 and the CAS number is 205594-89-4.Formule :C45H84O7Couleur et forme :SolidMasse moléculaire :737.16Pyrazine
CAS :Compound PDK0166, with CAS No. 290-37-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0166 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C4H4N2Masse moléculaire :80.08hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Couleur et forme :Odour SolidImpurity C of Calcitriol
CAS :Impurity C of Calcitriol is an impurity of Calcitriol.Impurity C of Calcitriol is used in the synthesis of vitamin D3.Formule :C35H49N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :591.78Rovicurt
CAS :Rovicurt is use as a pesticide.Formule :C40H45Cl2NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :722.7hDHODH-IN-16
hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.Formule :C18H20N2O2Couleur et forme :SolidMasse moléculaire :296.36Mevinolinic acid
CAS :Mevinolinic acid is an active metabolite of Lovastatin. Lovastatin is an HMG-CoA reductase inhibitor.Formule :C24H38O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.562Ninopterin
CAS :Ninopterin is an experimental antineoplastic and folic acid analog.Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42D-Ribose 5-phosphate
CAS :Ribose 5-phosphate: Intermediate in oxidative PPP, final in non-oxidative PPP, used for nucleotide and nucleic acid synthesis.Formule :C5H11O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :230.11PTP1B-IN-22
CAS :PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.Formule :C16H12N2O3S2Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :344.41isomer-GAT 107
CAS :isomer-GAT 107 ((-)GAT 107) is an inactive isomer of (+)GAT 107.Formule :C18H17BrN2O2SDegré de pureté :99.33%Couleur et forme :SoildMasse moléculaire :405.31Butenachlor
CAS :Butenachlor is a pesticide, specifically a selective, soil-applied herbicide used for control of grass and some broad-leaved weeds.Formule :C17H24ClNO2Couleur et forme :SolidMasse moléculaire :309.83Deacetylforskolin
CAS :Deacetylforskolin, a diterpene derivative of forskolin, acts on rat adipocytes and lowers hypertensive rats' blood pressure.Formule :C20H32O6Couleur et forme :SolidMasse moléculaire :368.47Trichloroacetic acid
CAS :Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.Formule :C2HCl3O2Couleur et forme :SolidMasse moléculaire :163.395,7-Dichloropyrazolo[1,5-a]pyrimidine
CAS :5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is an inhibitor of the enzyme phosphodiesterase 10A (PDE10A) with a Ki value of 24 μM. This compound can be employed in research related to schizophrenia.Formule :C6H3Cl2N3Couleur et forme :SolidMasse moléculaire :188.013-O-methyl-L-DOPA (hydrate)
CAS :3-O-methyl-L-DOPA, a L-DOPA metabolite from catechol O-methyltransferase, may impact or compete with L-DOPA.Formule :C10H15NO5Couleur et forme :SolidMasse moléculaire :229.23Galactosylhydroxylysine hydrochloride
Galactosylhydroxylysine hydrochloride, found in bone collagen, is higher in metabolic bone loss due to resorption.Formule :C12H25ClN2O8Couleur et forme :SolidMasse moléculaire :360.79Lysinoalanine, (S,R)-
CAS :Lysinoalanine, (S,R)- is a bioactive chemical.Formule :C9H19N3O4Couleur et forme :SolidMasse moléculaire :233.26DNP-INT
CAS :DNP-INT, a quinone analog, blocks plant electron transport; it binds cytochrome b6f's Qo, halting plastoquinol oxidation (Kd 1.4 nM).Formule :C16H14IN3O7Couleur et forme :SolidMasse moléculaire :487.2MCI-INI-3
CAS :MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formule :C19H16ClN3O5S2Couleur et forme :SolidMasse moléculaire :465.93(R)-SCH 42495
CAS :(R)-SCH 42495, less potent enantiomer of NEP inhibitor SCH 42495, has oral antihypertensive action.Formule :C20H29NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.58Propionylcarnitine
CAS :Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptuFormule :C10H19NO4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :217.26Saccharopine
CAS :L-Saccharopine is a product of the breakdown of essential amino acid Lysine.Formule :C11H20N2O6Couleur et forme :SolidMasse moléculaire :276.29Naphthacene
CAS :Naphthacene (Benz[b]anthracene) is a useful life science reagent for biochemical experiments and organic synthesis.Formule :C18H12Masse moléculaire :228.29RORγt inverse agonist 33
RORγt inverse agonist 33 (compound (R)-D4) is an orally bioavailable RORγt inverse agonist with an IC50 of 21 nM, playing a significant role in rheumatoid arthritis research.Formule :C27H37NO5SCouleur et forme :SolidMasse moléculaire :487.651Allotetrahydrocortisol
CAS :Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human.Formule :C21H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.49CK2-IN-13
CK2-IN-13 (compound 12c) is a potent inhibitor of CK2, with an IC50 value of 5.8 nM, playing a significant role in cancer research.Formule :C19H13Br2NO3Couleur et forme :SolidMasse moléculaire :463.119Dactylocycline A
CAS :Dactylocyclines A: novel antibiotic from Dactylosporangium, effective against tetracycline-resistant microbes.Formule :C31H40ClN3O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :698.11hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formule :C22H20N4O6S2Couleur et forme :SolidMasse moléculaire :500.547ISM012-042
ISM012-042 is an orally active inhibitor of PHD1 and PHD2, with IC50 values of 1.9 and 2.5 nM, respectively. At a concentration of 2.5 μM, ISM012-042 protects Caco-2 cells from DSS-induced barrier damage. Additionally, in LPS-induced bone marrow-derived dendritic cells (BMDC) from mice, ISM012-042 exhibits anti-inflammatory properties by dose-dependently reducing the expression of IL-12 subunit IL-12p35 and TNF. It also restores intestinal barrier function and alleviates intestinal inflammation in various experimental colitis models. ISM012-042 is useful for studying intestinal mucosal repair and immune disorders.Formule :C26H28N6O4Couleur et forme :SolidMasse moléculaire :488.538tetranor-12(R)-HETE
CAS :Corneal metabolism of 12(R)-HETE yields 8(R)-HHxTrE via β-oxidation, losing four carbons from C-1.Formule :C16H26O3Couleur et forme :SolidMasse moléculaire :266.381Endocrocin
CAS :Endocrocin is a useful organic compound for research related to life sciences. The catalog number is T124800 and the CAS number is 481-70-9.Formule :C16H10O7Couleur et forme :SolidMasse moléculaire :314.2494-Hydroxy Atorvastatin calcium salt
CAS :4-Hydroxy Atorvastatin calcium salt is metabolised by cytochrome P450 CYP3A4 and has antimicrobial and anti-microbial activity.
Formule :C66H68CaF2N4O12Couleur et forme :SolidMasse moléculaire :1187.348-iso-13,14-dihydro-15-keto Prostaglandin F2α
CAS :8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits,Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.48SHP2-IN-34
CAS :SHP2-IN-34 (compound A8) is a phenylurea SHP2 inhibitor with anti-cancer properties. It significantly suppresses tumor growth in CT26 mouse models.Formule :C23H25Cl2N7OSCouleur et forme :SolidMasse moléculaire :518.46
![5,7-Dichloropyrazolo[1,5-a]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT203531.webp&w=3840&q=75)
