Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(139 produits)
- DHFR(30 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(63 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(233 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(36 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(62 produits)
- Lipoxygénase(134 produits)
- MAO(84 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(84 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(17 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(30 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9198 produits trouvés pour "Métabolisme"
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JNJ 42396302
CAS :JNJ 42396302 is an effective PDE10A inhibitor that enhances motility and viability in human sperm cells.Formule :C19H23N5O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :353.42Alanopine
CAS :Alanopine is an aminoacid.Formule :C6H11NO4Couleur et forme :SolidMasse moléculaire :161.16RMC-4630
CAS :RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.Formule :C20H27ClN6O2SDegré de pureté :99.07% - 99.65%Couleur et forme :SolidMasse moléculaire :450.99Ref: TM-T39658
1mg120,00€5mg294,00€1mL*10mM (DMSO)324,00€10mg467,00€25mg807,00€50mg1.071,00€100mg1.468,00€3-Hydroxyanisole
CAS :3-Hydroxyanisole has inhibitory activity against MAO-A (IC50 = 24 ± 2.8 μM) and can be used to study neurological and psychiatric diseases.Formule :C7H8O2Degré de pureté :98.96%Couleur et forme :Clear Pink To Red Liquid With The Odor Of Phenol And CarmelMasse moléculaire :124.14CK2-IN-14
CK2-IN-14 (Compound 10b) is an inhibitor of cyclin-dependent kinase 2α with an IC50 of 36.7 nM. It effectively hinders the growth of cancer cell lines 786-O and U937, with GI50 values of 7.3 μM and 7.5 μM, respectively.Formule :C19H20ClN5SCouleur et forme :SolidMasse moléculaire :385.91Kitol
CAS :Kitol is a crystalline alcohol capable of yielding vitamin A.Formule :C40H60O2Couleur et forme :SolidMasse moléculaire :572.90Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Couleur et forme :Odour LiquidPROTAC sEH-degrader-1
sEH-degrader-1 (Compound 8) acts as an effective inhibitor of sEH, exhibiting IC50 values of 3.8 nM for hsEH and 210 nM for msEH. Additionally, it proficiently degrades sEH in both mouse liver and brown adipose tissue.Formule :C53H65F3N8O9Couleur et forme :SolidMasse moléculaire :1015.13Omfiloctocog alfa
CAS :Omfiloctocog alfa (SCT-800) is a recombinant FVIII for Hemophilia A research.Couleur et forme :LiquidC20 Sphingomyelin (d18:1/20:0)
CAS :C20 sphingomyelin rises in diabetic rats, obese humans with insulin resistance, and Niemann-Pick C1 mice; it falls in men with prostate cancer.Formule :C43H87N2O6PCouleur et forme :SolidMasse moléculaire :759.151Ac-ESMD-CHO
CAS :Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (Formule :C19H30N4O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.53Choline-d13 chloride
CAS :Choline-d13(chloride) is a deuterated form of Choline chloride. Choline chloride, an organic compound and a quaternary ammonium salt, acts as both a substrate for acyl receptors and choline acetyltransferase. It serves as a photosynthesis enhancer in plants and is also used as a feed additive for poultry and livestock to boost egg and offspring production.Formule :C5H14ClNOCouleur et forme :SolidMasse moléculaire :152.70Sacubitril-13C4 hemicalcium salt
Sacubitril-13C4 (hemicalcium salt) is the carbon-13 and deuterium-labeled version of Sacubitril hemicalcium salt. Sacubitril (AHU-377) hemicalcium salt is a potent NEP inhibitor with an IC50 value of 5 nM. It is a component of the active pharmaceutical compound LCZ696, used in heart failure research.Couleur et forme :Odour Solid3-Indoleacetic acid-d4
CAS :3-Indoleacetic acid-d4 (Indole-3-acetic acid-d4; 3-IAA-d4) is a deuterium-labeled form of 3-Indoleacetic acid. It is the most prevalent natural plant growth hormone within the auxin class. When added to cell culture media, it can stimulate the elongation and division of plant cells.Formule :C10H9NO2Couleur et forme :SolidMasse moléculaire :179.21Human Endogenous Metabolite Compound Library Plus
A unique collection of xnum endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.Couleur et forme :Odour SolidRef: TM-L2501
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderN-Desmethyl Sildenafil
CAS :N-Desmethyl Sildenafil (UK-103,320) (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5).Formule :C21H28N6O4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :460.55Ref: TM-T36061
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg78,00€25mg142,00€50mg220,00€100mg321,00€200mg477,00€PFKFB3-IN-2
CAS :PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.Formule :C14H11NO7SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :337.3Ref: TM-T67874
5mg49,00€1mL*10mM (DMSO)51,00€10mg71,00€25mg110,00€50mg164,00€100mg225,00€200mg330,00€MS-PPOH
CAS :MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectivelyFormule :C16H21NO4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :323.411-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
CAS :Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.
Formule :C40H80NO8PDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :734.04(Ile8)-Oxytocin acetate
(Ile8)-Oxytocin acetate is a neurohypophysial hormone analog of oxytocin produced in marsupials.Formule :C45H70N12O14S2Couleur et forme :SolidMasse moléculaire :1067.24SR-4995
CAS :SR-4995 (CID 16016685) is an ABHD5 ligand, directly binding to ABHD5 and stimulating lipolysis by releasing it from PLIN.Formule :C19H21N3O2SCouleur et forme :SoildMasse moléculaire :355.45α-glucosidase/PTP1B-IN-1
α-glucosidase/PTP1B-IN-1 (compound 8a) is an effective inhibitor of both α-glucosidase and PTP1B, with IC50 values of 66.3 μM and 47.0 μM, respectively. It also exhibits strong inhibitory activity against α-amylase, having an IC50 of 30.62 μM. This compound is capable of binding to the active sites of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 holds potential for reducing postprandial blood glucose levels and may be useful in managing type 2 diabetes.Formule :C23H20Cl2O5Couleur et forme :SolidMasse moléculaire :447.31TC HSD 21
CAS :TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formule :C17H12BrNO3S2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :422.32Ref: TM-T13100
1mg39,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg130,00€25mg225,00€50mg326,00€100mg439,00€200mg592,00€PF-1355
CAS :PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
Formule :C14H15N3O4SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :321.35Ref: TM-T3511
500mgÀ demander2mg35,00€5mg50,00€10mg80,00€25mg116,00€50mg212,00€100mg305,00€200mg437,00€ML251
CAS :ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formule :C17H13Cl2N3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :426.27Ref: TM-T64320
1mg109,00€5mg260,00€1mL*10mM (DMSO)285,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€200mg1.728,00€O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formule :C24H22N5NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.5217β-HSD10-IN-1
CAS :17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.Formule :C16H13ClN4O3SDegré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :376.82MSNBA
CAS :MSNBA inhibits GLUT5 fructose uptake (KI: 3.2±0.4 μM) in MCF7 cells, serving as a potent GLUT5 probe.Formule :C14H12N2O6SDegré de pureté :99.95%Couleur et forme :SoildMasse moléculaire :336.32CAY10640
CAS :CAY10640 (sEH inhibitor-1) is a potent, orally active, water-soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in humans and mice with IC50s of 0.4Formule :C17H20F3N3O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :371.35Glycodehydrocholic acid
CAS :Glycodehydrocholic acid is a bile acid compound formed by conjugation of bile acid with glycine.
Formule :C26H37NO6Couleur et forme :SolidMasse moléculaire :459.58PAz-PC
CAS :PAz-PC (Azelaoyl PC) is a truncated phospholipid oxidation product that enhances endothelial barrier disruption caused by HKSA.Formule :C33H64NO10PCouleur et forme :SolidMasse moléculaire :665.84POPG sodium salt
CAS :POPG sodium salt is a phospholipid and a component of biological membranes and can be used to study the function of biological membranes.Formule :C40H76NaO10PDegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :770.99hDHODH-IN-8
CAS :hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.Formule :C21H15F6N3O4Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :487.35TP0472993
CAS :CYP4A11/CYP4F2-IN-2: Potent oral inhibitor of CYP4A11 & CYP4F2 (IC50: 140 & 40 nM), potential kidney disease treatment.Formule :C16H20N4O2Degré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :300.36Ref: TM-T67916
1mg49,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg160,00€25mg305,00€50mg492,00€100mg710,00€500mg1.468,00€N-Desmethyl Bendamustine
CAS :N-DesmethylBendamustine is a metabolite of Bendamustine. It exerts cytotoxic effects on various lymphoma cell lines and peripheral blood lymphocytes.Formule :C15H19Cl2N3O2Couleur et forme :SolidMasse moléculaire :344.24APP-018
CAS :APP-018 (D-4F) is an 18 D-amino acid peptide that mimics apolipoprotein A-I (apoA-I). It enhances the anti-inflammatory properties of high-density lipoprotein (HDL) and is applicable in cardiovascular disease research.Formule :C114H156N24O28Couleur et forme :SolidMasse moléculaire :2310.611-Hydroxy cannabinol
CAS :11-Hydroxy cannabinol (Compound 5b) is an active metabolite of cannabinol.Formule :C21H26O3Couleur et forme :SolidMasse moléculaire :326.43b-Cortolone
CAS :b-Cortolone, a metabolite of Cortisol, exhibits relatively lower biological activity.Formule :C21H34O5Couleur et forme :SolidMasse moléculaire :366.49cMCoFx1
CAS :cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formule :C146H232N52O44S6Couleur et forme :SolidMasse moléculaire :3612.12ChAT IN-1
ChAT IN-1 is a selective inhibitor of Choline Acetyltransferase (ChAT) that is utilized in studying mechanisms related to non-neuronal ChAT overexpression in cancers such as colon cancer and lung cancer, as well as in research concerning Alzheimer's disease (AD).Formule :C21H15N3O2Couleur et forme :SolidMasse moléculaire :341.36Norfenfluramine hydrochloride
CAS :Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, resulting from its N-dealkylation. It serves as a potent anorectic agent and can modulate serotonin neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects following acute administration.Formule :C10H13ClF3NCouleur et forme :SolidMasse moléculaire :239.67Adenosine 3',5'-diphosphate sodium salt
CAS :Adenosine 3',5'-diphosphate sodium inhibits hydroxysteroid sulfotransferases and studies SULT kinetics/structure.Formule :C10H15N5NaO10P2Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :450.19Inostamycin A
CAS :Inostamycin A, a anticancer bacterial metabolite isolated from Streptomyces, is a selective inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase.Formule :C38H68O11Couleur et forme :SolidMasse moléculaire :700.94Pyruvate carboxylase
CAS :Pyruvate carboxylase, a biotin-containing enzyme, catalyzes the carboxylation of pyruvate to oxaloacetate, a reaction dependent on HCO3− and MgATP.Degré de pureté :98%Couleur et forme :SolidAntidiabetic agent 2
Compound 56 (Antidiabetic agent 2) is a glucose-uptake promoter that inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase, with IC50 values of 0.036, 0.042, 0.Formule :C25H21N5O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :599.59Mortatarin G
Mortatarin G (compound 3), a prenylated flavonoid derived from mulberry leaves, demonstrates potent α-glucosidase inhibition, evidenced by an IC50 value of 20.4Formule :C25H28O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.49α-Amylase/α-Glucosidase-IN-4
α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50Formule :C32H26N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.58RORγ antagonist 1
RORγ antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to RORγ with a dissociation constant (K D) of 0.18 μM.Formule :C35H60N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.86α,α-Trehalose 6-phosphate potassium
CAS :α,α-Trehalose 6-phosphate (Tre6P) potassium is an intrinsic 6-phosphate derivative of α,α′-trehalose and acts as an intermediary metabolite.Formule :C12H21K2O14PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.46His-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, a growth hormone releasing peptide and metabolite of GHRP-1 (Ala-His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2), stimulatesFormule :C50H58F3N11O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :998.06
