Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(196 produits)
- Caséine Kinase(138 produits)
- DHFR(32 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(85 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(226 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(57 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(61 produits)
- Lipoxygénase(134 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(86 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(22 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(29 produits)
- Tansporteur(45 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
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9182 produits trouvés pour "Métabolisme"
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Calcitriol lactone
CAS :Calcitriol lactone (1α,25-Dihydroxyvitamin D3-26,23-lactone), a vitamin D3 metabolite, serves as the active form of vitamin D, influencing bone health, cell differentiation, and immune function.Formule :C27H40O5Couleur et forme :SolidMasse moléculaire :444.60Bilirubin Conjugate (sodium salt)
CAS :Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives.Formule :C37H46N6Na2O10S2Couleur et forme :SolidMasse moléculaire :844.91Methyl Diethyldithiocarbamate
CAS :Methyl diethyldithiocarbamate, a disulfiram metabolite, inhibits rat ALDH (ID50=15.5mg/kg) and affects MAP and heart rate during ethanol challenge.Formule :C6H13NS2Couleur et forme :SolidMasse moléculaire :163.36',7'-Epoxybergamottin
CAS :6'7'-Epoxybergamottin: Found in grapefruit; inhibits CYP3A4 (IC50: 0.30 ppm); presents in juice (0.1-7.4 μM); blocks talinolol transport; is insecticidal.Formule :C21H22O5Couleur et forme :SolidMasse moléculaire :354.4Glycerophospho-N-Palmitoyl Ethanolamine
CAS :N-Acylated ethanolamines (NAEs) are bioactive lipids; AEA activates CB1/CB2 receptors; PEA, an anti-inflammatory, doesn't bind well to them.Formule :C21H44NO7PCouleur et forme :SolidMasse moléculaire :453.557hCA-I/hCA-II-IN-1
hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual inhibitor of human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II), with Ki values of 0.22 μM and 0.33 μM respectively. hCA-I/hCA-II-IN-1 is useful for research into diseases related to CA enzymes, including glaucoma, hypertension, and ulcers.Couleur et forme :Odour SolidCyPep-1
CAS :CyPep-1 is a novel cationic lytic peptide with antitumor activity. It exerts potent cytotoxicity by interacting with the negatively charged membranes of cancer cells. CyPep-1 demonstrates strong cell lytic activity against cancer cells both in vitro and in vivo, making it useful for researching solid tumors.Formule :C152H265N57O35Couleur et forme :SolidMasse moléculaire :3451.09(Rac)-PDE4-IN-4
(Rac)-PDE4-IN-4 is a diastereomeric mixture of PDE4-IN-4. PDE4-IN-4 acts as an M3 antagonist (pIC50 = 10.2) and a PDE4 inhibitor (pIC50 = 8.8), and it is utilized in inhalation studies related to pulmonary diseases.Formule :C36H37Cl2N3O7SMasse moléculaire :725.17293IR-117-17
CAS :IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.Formule :C59H110N2O5Couleur et forme :SolidMasse moléculaire :927.52Folitixorin calcium, (6R)-
CAS :Folitixorin calcium, a calcium salt form of (6R)-Folitixorin, aids enzyme production of 5-methyltetrahydrofolate.Formule :C20H21CaN7O6Couleur et forme :SolidMasse moléculaire :495.5021-Deoxy Cortisone
CAS :21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.Formule :C21H28O4Couleur et forme :SolidMasse moléculaire :344.44ROS-IN-3
ROS-IN-3 (compound x38) is an inhibitor of ROS and is utilized in neuro-related research.Formule :C25H20F2N2O4Couleur et forme :SolidMasse moléculaire :450.43Xenin
CAS :Xenin is a 25 amino acid peptide that has been identified in human gastric mucosa in the search for a counterpart to the amphibian octapeptide xenopsin.Formule :C139H224N38O32SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2971.57sPLA2 inhibitor 3
sPLA2 inhibitor 3 (Compound 6c) functions as a potent α-glucosidase inhibitor (IC50= 0.0953 µM) and has potential applications in diabetes research.Formule :C22H16F6N6O4S2Couleur et forme :SolidMasse moléculaire :606.52Hypusine HCl
CAS :Hypusine HCl: a unique amino acid in eukaryotes/archaea, absent in bacteria; only in eIF5A protein.Formule :C10H25Cl2N3O3Couleur et forme :SolidMasse moléculaire :306.23CRT0063465
CRT0063465 is a ligand for both human Phosphoglycerate Kinase 1 (PGK1) and the stress sensor protein DJ-1, exhibiting a dissociation constant (Kd) of 24 μM forCouleur et forme :Odour Solidα-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formule :C25H22N6OS2Couleur et forme :SolidMasse moléculaire :486.61Nicanartine
CAS :Nicanartine is a cholesterol inhibitor that is used to treat cardiovascular disease and can be used to study atherosclerosis.Formule :C23H33NO2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :355.51Coenzyme Q6
CAS :Coenzyme Q6, also Ubiquinone 30, is a benzoquinone lipid aiding respiration and acting as an antioxidant.
Formule :C39H58O4Couleur et forme :SolidMasse moléculaire :590.881-Palmitoyl Lysophosphatidic Acid (sodium salt)
CAS :1-Palmitoyl LPA: a palmitic acid-containing LPA analog, targets GPCRs, affects cell responses, and boosts β-lactam antibiotics against Pseudomonas aeruginosa.Formule :C19H38NaO7PCouleur et forme :SolidMasse moléculaire :432.46Bacterial α-Amylase
CAS :Bacterial α-Amylase is an enzyme that catalyzes the hydrolysis reaction of starch into smaller sugar molecules such as maltose and glucose.Couleur et forme :SolidIsobutyl Butyrate
CAS :Isobutyl Butyrate is a butyrate ester formed by the condensation of butyric acid with isobutyl alcohol, which is a metabolite of rifampicin.Formule :C8H16O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :144.21Acetoacetic acid
CAS :Acetoacetic acid(3-oxobutanoic acid) is a oxidative stress inducer, gluconeogenesis, and can be used as an indicator of in ketoacidosis.Formule :C4H6O3Degré de pureté :99.59% - 99.85%Couleur et forme :SolidMasse moléculaire :102.09DSPE-PEG2000-TH
DSPE-PEG2000-TH is a PEG conjugate made from DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments—such as the tumor microenvironment—TH becomes activated, allowing for the selective delivery of small molecules, oligonucleotides, and proteins into tumor cells.Couleur et forme :Odour SolidPTP Inhibitor IV
CAS :PTP Inhibitor IV selectively inhibits DUSP14 (IC50=5.21µM) and other PTPs, affecting cellular signaling.
Formule :C26H26F6N2O4S2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :608.62DSPE-PEG2000-GRGDS
DSPE-PEG2000-GRGDS is a PEG-based compound formed from DSPE and the anti-adhesion peptide (GRGDS). GRGDS serves to inhibit the binding and adhesion between the extracellular matrix and cell surface integrins. This compound is applicable in drug delivery.Couleur et forme :Odour SolidDSPE-PEG2000-R9
DSPE-PEG2000-R9 is a PEG compound composed of DSPE and polyarginine-9 peptide (R9) peptide. It can be used for drug delivery.Couleur et forme :Odour SolidDSPE-PEG3000-TAASGVRSMH
DSPE-PEG3000-TAASGVRSMH is a PEG compound composed of DSPE and TAASGVRSMH. TAASGVRSMH exhibits a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG3000-TAASGVRSMH can be utilized in drug delivery.Couleur et forme :Odour SolidDSPE-PEG3000-LyP-1
DSPE-PEG3000-LyP-1 is a PEG compound composed of DSPE and a nine-residue peptide (LyP-1). The LyP-1 component specifically targets tumor-associated lymphatics and macrophages.Couleur et forme :Odour SolidDSPE-PEG5000-pPB
DSPE-PEG5000-pPB is a PEG compound composed of DSPE and the cyclic oligopeptide (pPB). The pPB component has high binding affinity to PDGFRβ, which is overexpressed on activated hepatic stellate cells (HSC). DSPE-PEG5000-pPB is applicable for drug delivery.Couleur et forme :Odour SolidDSPE-PEG2000-ANG
DSPE-PEG2000-ANG is a PEG compound composed of DSPE and the dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high binding efficiency to LRP1 and has been used for targeted delivery to gliomas. DSPE-PEG2000-ANG can be utilized in drug delivery applications.Couleur et forme :Odour SolidDSPE-PEG1000-T7
DSPE-PEG1000-T7 is a PEG compound composed of DSPE and transferrin receptor peptide (T7). The T7 peptide (HAIYPRH) specifically binds to TfR. DSPE-PEG1000-T7 is applicable in drug delivery.Couleur et forme :Odour SolidDSPE-PEG5000-M2pep
DSPE-PEG5000-M2pep is a PEG compound composed of DSPE and the M2 macrophage-targeting peptide (M2pep). Serving either as a monovalent or multivalent ligand, M2pep is conjugated with pro-apoptotic peptides to direct toxicity specifically toward M2 macrophages. DSPE-PEG5000-M2pep is applicable for drug delivery.Couleur et forme :Odour SolidDSPE-PEG3000-TAT
DSPE-PEG3000-TAT is a PEG compound composed of DSPE and a cell-penetrating peptide (TAT). It is used for drug delivery.Couleur et forme :Odour SolidGGACK hydrochloride
GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).
Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.13417C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS :C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.Couleur et forme :SolidIONIS PTP1BRx sodium
IONIS PTP1BRx (ISIS 404173) sodium, an antisense inhibitor of protein tyrene phosphatase 1B (PTP-1B), exhibits antidiabetic properties. This compound is utilzed in researching insulin resistance and type 2 diabetes mellitus associated with obesity.Couleur et forme :Odour SolidESI1
ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.Formule :C18H18ClN5OCouleur et forme :SolidMasse moléculaire :355.82Galactose 1-dehydrogenase
Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.Couleur et forme :Odour SolidMethyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate
CAS :Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.Formule :C25H40O4Couleur et forme :SolidMasse moléculaire :404.58N-Benzoyl-L-Leucine
CAS :N-Benzoyl-L-Leucine is a leucine derivative exhibiting antibacterial activity against Staphylococcus aureus.Formule :C13H17NO3Degré de pureté :99.60%Couleur et forme :SoildMasse moléculaire :235.28Cysteinylglycine acetate
Cysteinylglycine acetate (Cys-Gly Acetate) is an acetate salt of Cysteinylglycine.
Formule :C7H14N2O5SDegré de pureté :99.49%Couleur et forme :SoildMasse moléculaire :238.26human TDO2-IN-1
Human TDO2-IN-1 (Cpd-2) is a potent inhibitor of human TDO2, with an IC50 of 14.8 nM. It plays a significant role in studies related to metabolism, inflammation, and tumor immune surveillance.
Formule :C30H36N4O5Couleur et forme :SolidMasse moléculaire :532.631Adrenergic Receptor-Targeted Compound Library
A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;Couleur et forme :Odour SolidRef: TM-L2700
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderONO-8430506
CAS :ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.Formule :C27H28FN3O3Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :461.53Ref: TM-T38759
1mg103,00€5mg244,00€10mg338,00€25mg510,00€50mg687,00€100mg919,00€1mL*10mM (DMSO)271,00€SGK1-IN-4
CAS :SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.Formule :C23H21ClFN5O4SDegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :517.96Ref: TM-T9977
1mg105,00€5mg250,00€10mg356,00€25mg580,00€50mg782,00€100mg1.044,00€200mg1.404,00€1mL*10mM (DMSO)301,00€hBChE-IN-3
hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.Couleur et forme :Odour SolidXanthine oxidase-IN-16
Xanthine oxidase-IN-16 is an effective orally active inhibitor of xanthine oxidase (XO), demonstrating significant therapeutic efficacy in rats with hyperuricemia and an IC50 of 102 nM.Couleur et forme :Odour Solidγ-glutamyltransferase
CAS :γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.Couleur et forme :SolidDSPE-PEG5000-NGR
DSPE-PEG5000-NGR is a PEG compound composed of DSPE and the Asn-Gly-Arg (NGR) peptide. The NGR peptide has the capability to target tumor vasculature antigen CD13. DSPE-PEG5000-NGR is applicable in drug delivery.
Couleur et forme :Odour Solid
