Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(197 produits)
- Caséine Kinase(137 produits)
- DHFR(34 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(303 produits)
- FAAH(66 produits)
- FXR(62 produits)
- Facteur Xa(87 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(226 produits)
- GR(3 produits)
- GSNOR(4 produits)
- Glucokinase(57 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(35 produits)
- IDO(84 produits)
- LDL(8 produits)
- Lipase(107 produits)
- Lipides(61 produits)
- Lipoxygénase(134 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(167 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(169 produits)
- Phospholipase(83 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(28 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(29 produits)
- Tansporteur(46 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
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9282 produits trouvés pour "Métabolisme"
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3,4-Dihydroxyamphetamine hydrochloride
CAS :3,4-Dihydroxyamphetamine (α-Methyldopamine) (hydrochloride) is a minor metabolite of 3,4-Methylenedioxymethamphetamine (MDMA) and exhibits cytotoxicity in rat hepatocytes. Additionally, 3,4-Dihydroxyamphetamine (hydrochloride) is applicable in hypertension research.Formule :C9H14ClNO2Couleur et forme :SolidMasse moléculaire :203.67LH1513
LH1513 is a dioxalate salt derivative of l-lysine that inhibits CaOx crystallization more effectively than citrate and pyruvate. It shows potential preventive activity in hyperoxaluria models and effectively prevents urinary CaOx crystal formation in Agxt knockout mice. AGXT-1 is a mitochondrial protein involved in metabolic processes.Formule :C10H11N2Na3O8Couleur et forme :SolidMasse moléculaire :356.17LXQ-87
CAS :LXQ-87 is an orally administered, non-competitive inhibitor of PTP1B with an IC50 of 1.061 μM, demonstrating hypoglycemic activity. It alleviates insulin resistance and enhances cellular glucose uptake, making it useful for type 2 diabetes research.Formule :C23H18Br2O5Couleur et forme :SolidMasse moléculaire :534.195-Aminoisotonitazene
CAS :5-Aminoisotonitazene is a metabolite of the synthetic opioid analgesic agent, Isotonitazene, found in urine.Formule :C23H32N4OCouleur et forme :SolidMasse moléculaire :380.535-(3',4'-Dihydroxyphenyl)-γ-valerolactone
CAS :5-(3',4'-Dihydroxyphenyl)-γ-valerolactone is a metabolic byproduct of gut microbiota processing of (-)-Epicatechin. [5-(3',4'-Dihydroxyphenyl)-γ-valerolactone] exhibits antioxidant properties.Formule :C11H12O4Couleur et forme :SolidMasse moléculaire :208.21LZ-007
CAS :LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.Formule :C27H29F3N2O5Couleur et forme :SolidMasse moléculaire :518.53α-Glucosidase-IN-76
α-Glucosidase-IN-76 (Compound 4r) is an inhibitor of α-glucosidase, with an IC50 of 5.44 μM. It can clear ABTS+ free radicals, with a TEAC value of 0.49. Additionally, α-Glucosidase-IN-76 inhibits the proliferation of T24 bladder cancer cells, with an IC50 of 1.74 μM.Formule :C21H24N4O10Couleur et forme :SolidMasse moléculaire :492.44PDE5-IN-10
PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,Formule :C21H20N4O2Couleur et forme :SolidMasse moléculaire :360.41Pi-Methylimidazoleacetic acid
CAS :Pi-Methylimidazoleacetic acid is a potential neurotoxin.Formule :C6H8N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :140.14Diphlorethohydroxycarmalol
CAS :<p>Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.</p>Formule :C24H16O13Couleur et forme :SolidMasse moléculaire :512.3793-Oxo-7-hydroxychol-4-enoic acid
CAS :3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.Formule :C24H36O4Couleur et forme :SolidMasse moléculaire :388.54APOL1-IN-2
CAS :APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1). It effectively reduces HEK293 cell death induced by APOL1 G2/G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2/G1/G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.Formule :C28H30ClF3N4O5Couleur et forme :SolidMasse moléculaire :595.012-Hydroxyquinoline
CAS :Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C9H7NOCouleur et forme :White SolidMasse moléculaire :145.15Norpropranolol hydrochloride
CAS :Norpropranolol hydrochloride is the active metabolite of Propranolol.Formule :C13H16ClNO2Couleur et forme :SolidMasse moléculaire :253.73L-Cysteine-glutathione disulfide
CAS :L-Cysteine-glutathione disulfide is a biomarker for curing tuberculosis, useful in researching acetaminophen-induced liver toxicity.Formule :C13H22N4O8S2Couleur et forme :SolidMasse moléculaire :426.47cis-Vitamin K1
CAS :<p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>Formule :C31H46O2Couleur et forme :SolidMasse moléculaire :450.701-Salicylate Glucuronide
CAS :<p>1-Salicylate Glucuronide (Salicylic Acid b-D-O-Glucuronide) is a metabolite of salicylic acid after glucuronidation, promoting excretion.</p>Formule :C13H14O9Couleur et forme :SolidMasse moléculaire :314.25FXR agonist 5
CAS :FXR agonist 5 is an FXR agonist used in the study of liver diseases or diseases mediated by metabolic inflammation.Formule :C40H53N5O5Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :683.88α-Glucosidase-IN-82
α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-glucosidase, with an IC50 value of 13.66 μM. Its inhibitory activity is 52 times greater than that of Acarbose.Formule :C30H24N4O4Couleur et forme :SolidMasse moléculaire :504.536α-Hydroxytamoxifen
CAS :α-Hydroxytamoxifen is a metabolite of tamoxifen. It reacts with DNA and causes the formation of DNA adducts.Formule :C26H29NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.5113,14-dehydro-15-cyclohexyl Carbaprostacyclin
CAS :13,14-dehydro-15-cyclohexyl Carbaprostacyclin, a stable PGI2 analog, impedes ADP-induced platelet aggregation; ED50 ~40 nM in PRP, 77 nM in washed platelets.Formule :C21H30O4Couleur et forme :SolidMasse moléculaire :346.46713-cis-Retinyl acetate
CAS :13-cis-Retinyl acetate: active 13-cis isomer of Retinyl acetate, metabolite of vitamin A.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49Methylcardol triene
CAS :Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.496Carboxyaminoimidazole ribotide
CAS :CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.Formule :C9H14N3O9PCouleur et forme :SolidMasse moléculaire :339.2Febuxostat dicarboxylic acid impurity
CAS :Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .Formule :C16H17NO5SCouleur et forme :SolidMasse moléculaire :335.38Anticancer agent 232
Anticanceragent 232 (compound 12f) is a sugar hybrid designed from 1-azide glycosides derived from d-glucose, d-galactose, and d-mannose. The IC50 values for this compound are 1.05 μM against MCF-7 cells and 18.03 μM for MDA-MB231 cells.Formule :C32H31BrN4O11Masse moléculaire :726.11727FABP4-IN-4
FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.Couleur et forme :Odour SolidRubratoxin A
CAS :<p>Rubratoxin A is a classical mycotoxin used as a PP2A-specific inhibitor.</p>Formule :C26H32O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.531Citreoindole
CAS :Citreoindole: a diketopiperazine from P. citreovirde, cytotoxic against HeLa cells at 8.4 μM.Formule :C29H28N4O4Couleur et forme :SolidMasse moléculaire :496.56718:0,18:1 PS sodium
CAS :18:0,18:1 PS sodium, a lipid found in synaptic vesicles and cholesterol, serves a role in metabolic research [1].Formule :C42H79NNaO10PCouleur et forme :SolidMasse moléculaire :812.04Palitantin
CAS :Palitantin is a useful organic compound for research related to life sciences. The catalog number is T125757 and the CAS number is 15265-28-8.Formule :C14H22O4Couleur et forme :SolidMasse moléculaire :254.326D-myo-Inositol-1,4,5-triphosphate tripotassium
CAS :D-myo-Inositol-1,4,5-triphosphate tripotassium is a second messenger in the intracellular signaling system that induces Ca2+ mobilization.Formule :C6H12K3O15P3Couleur et forme :SolidMasse moléculaire :534.37SF-C5-TPP
SF-C5-TPP is an effective mitochondrial-targeting protonophore that acts as an uncoupler. It demonstrates significant proton transfer activity on model planar bilayer lipid membranes. SF-C5-TPP inhibits the growth of Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 2 μM.Formule :C41H46BrN2OPMasse moléculaire :692.25311N1-Acetylspermine
CAS :<p>N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].</p>Formule :C12H28N4OCouleur et forme :SolidMasse moléculaire :244.38α-Amylase-IN-11
α-Amylase-IN-11 (compound C5f) is an α-amylase inhibitor with an IC50 of 0.56 μM, effective in reducing glucose levels in vivo. Additionally, it exhibits moderate inhibitory activity against α-glucosidase with an IC50 of 11.03 μM. In mouse models, α-Amylase-IN-11 significantly decreases glucose concentrations, indicating its potential for diabetes research.Formule :C22H18N4OSCouleur et forme :SolidMasse moléculaire :386.47Lacto-N-biose I
CAS :Galβ1-3GlcNAc, a natural metabolite, is a substrate for H. pylori's α1,2-fucosyltransferase.Formule :C14H25NO11Couleur et forme :SolidMasse moléculaire :383.35Creatine kinase (OcCK)
CAS :Creatine kinase (OcCK) converts creatine and ATP into phosphocreatine and ADP, crucial for ATP/ADP balance during high energy demand.Couleur et forme :Solid15-keto Latanoprost (free acid)
CAS :15-keto Latanoprost, a less potent metabolite and impurity of latanoprost, lowers intraocular pressure in monkeys and constricts pupils in cats.Formule :C23H32O5Couleur et forme :SolidMasse moléculaire :388.5Etonitazene N-oxide
Etonitazene N-oxide (EtN-NOX) is a metabolite of the opioid compound Etonitazene.Couleur et forme :Odour SolidRawsonol
CAS :Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Formule :C29H24Br4O7Couleur et forme :SolidMasse moléculaire :804.11Sclerotiorin
CAS :Sclerotiorin, from Penicillium, inhibits soybean lipoxygenase-1 (IC50: 4.2 μM) and other proteins, antagonizes endothelin receptors.Formule :C21H23ClO5Couleur et forme :SolidMasse moléculaire :390.86Osmanthuside H
CAS :Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.4223-hydroxy Palmitic Acid
CAS :3-hydroxy palmitic acid (16:0 lipid) marks endotoxins, modifies genes in R. solanacearum, and accumulates in metabolic disorders, causing oxidative stress.Formule :C16H32O3Couleur et forme :SolidMasse moléculaire :272.42Manoyl oxide
CAS :<p>Manoyl oxide is a proposed intermediate in the biosynthesis of forskolin and other medically important labdane-type terpenoids.</p>Formule :C20H34OCouleur et forme :SolidMasse moléculaire :290.48Anticancer agent 111
Anticancer agent 111 (compound 11), exhibiting anticancer activity, serves as a potent inhibitor of cytochrome P450, particularly targeting CYP3A4 with anFormule :C42H60O4Couleur et forme :SolidMasse moléculaire :628.921,2-Dioleoyl-sn-glycero-3-PA ammonium salt
1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) is a phospholipid characterized by the incorporation of the long-chain fatty acid oleic acid at the sn-1 and sn-2 positions. It is utilized in the synthesis of artificial membranes such as liposomes.Couleur et forme :Odour SolidN,S-Bis-Fmoc-Glutathione
CAS :N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].Formule :C40H37N3O10SCouleur et forme :SolidMasse moléculaire :751.8(S)-3,4-Dihydroxybutyric acid lithium hydrate
(S)-3,4-Dihydroxybutyric acid (Li hydrate) is a urinary metabolite; higher in SSADH deficiency cases.Formule :C4H9LiO5Couleur et forme :SolidMasse moléculaire :144.05ACAT-IN-4 hydrochloride
CAS :ACAT-IN-4 hydrochloride is a potent ACAT inhibitor and blocks NF-κB transcription.Formule :C32H51ClN2O5SCouleur et forme :SolidMasse moléculaire :611.28C18:1 Ceramide (d18:1/18:1(9Z))
CAS :C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant , advanced ovarian cancer.Formule :C36H69NO3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :563.94
