Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(41 produits)
- Aminopeptidase(74 produits)
- CETP(20 produits)
- Anhydrase carbonique(185 produits)
- Caséine Kinase(137 produits)
- DHFR(34 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(289 produits)
- FAAH(65 produits)
- FXR(59 produits)
- Facteur Xa(83 produits)
- Synthase des acides gras(36 produits)
- Ferroptose(218 produits)
- GR(3 produits)
- GSNOR(4 produits)
- Glucokinase(56 produits)
- Prolyl-Hydroxylase de HIF/HIF(145 produits)
- HMG-CoA Réductase(33 produits)
- Hydroxylase(34 produits)
- IDO(84 produits)
- LDL(8 produits)
- Lipase(104 produits)
- Lipides(62 produits)
- Lipoxygénase(132 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(38 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(166 produits)
- PED(1 produits)
- PKM(15 produits)
- PPAR(168 produits)
- Phospholipase(82 produits)
- ROR(43 produits)
- Récepteur de rétinoïdes(28 produits)
- SGK(11 produits)
- Thioredoxine(12 produits)
- Transférase(29 produits)
- Tansporteur(43 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9054 produits trouvés pour "Métabolisme"
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Teprotide
CAS :<p>Teprotide is an angiotensin-converting enzyme (ACE) inhibitor used to study hypertensive [1].</p>Formule :C53H76N14O12Couleur et forme :SolidMasse moléculaire :1101.26UCM-13207
CAS :UCM-13207 is a specific ICMT inhibitor that improves progeria.Formule :C24H32N2O2Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :380.52Dansylphenylalanine
CAS :<p>Dansylphenylalanine is a typical fluorescent analyte.</p>Formule :C21H22N2O4SCouleur et forme :SolidMasse moléculaire :398.48Fexarene
CAS :<p>Fexarene is a non-steroidal FXR agonist.</p>Formule :C32H33NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.62Anticancer agent 111
Anticancer agent 111 (compound 11), exhibiting anticancer activity, serves as a potent inhibitor of cytochrome P450, particularly targeting CYP3A4 with anFormule :C42H60O4Couleur et forme :SolidMasse moléculaire :628.92PR280
<p>PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.</p>Formule :C27H49NO4Masse moléculaire :451.36616Raloxifene 6,4'-Bis-β-D-glucuronide
CAS :Raloxifene 6,4'-Bis-β-D-glucuronide is a Raloxifene metabolite. Raloxifene is a selective antagonist of estrogen receptor for the prevention of osteoporosis.Formule :C40H43NO16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :825.83Oglemilast
CAS :Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo.Formule :C20H13Cl2F2N3O5SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :516.3Kyotorphin
CAS :<p>Kyotorphin is a Morphine-like dipeptide.</p>Formule :C15H23N5O4Couleur et forme :SolidMasse moléculaire :337.38MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45VU533
CAS :VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formule :C21H22FN3O3S2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :447.55VU534
CAS :<p>VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related</p>Formule :C21H22FN3O3S2Degré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :447.55DSPE-PEG5000-VIP
DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.Couleur et forme :Odour Solid(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
CAS :(S,R,S)-AHPC-C2-amide targets Smad3 degradation and boosts HIF-α; it has anti-fibrotic and renal protective roles.Formule :C41H46N6O6SCouleur et forme :SolidMasse moléculaire :750.91DSPE-PEG2000-APRPG
DSPE-PEG2000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is utilized in drug delivery applications.Couleur et forme :Odour Solid20-hydroxy Leukotriene B4
CAS :<p>20-hydroxy LTB4, a LTB4 metabolite in neutrophils, is less active (~5%) but inhibits LTB4-induced degranulation, retains BLT2 affinity, non-agonist.</p>Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.471IDO1/TDO-IN-7
<p>IDO1/TDO-IN-7 (Compound 43b), an isochinoline derivative, functions as a potent dual inhibitor of IDO1/TDO with IC50 values of 0.31 μM and 0.08 μM, respectively. Demonstrating favorable pharmacokinetics and strong antitumor efficacy in the B16-F10 tumor model, this compound also exhibits low toxicity.</p>Couleur et forme :Odour SolidWH-15
CAS :WH-15: fluorogenic reporter for PLC-γ1, PLC-δ1, PLC-β2 with Km values of 49; 30, 86.1 µM. Cleaves to fluorescent 6-aminoquinoline for live cell imaging.Formule :C31H43N2O18P3Couleur et forme :SolidMasse moléculaire :824.6Anti-osteoporosis agent-10
<p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>Couleur et forme :Odour SolidROC-0929
CAS :<p>ROC-0929 (13a) is a selective sPLA2 inhibitor with IC50 of 80 nM, targeting hGX and blocking ERK1/2, p-38 phosphorylation for inflammation research.</p>Formule :C30H31N3O6SCouleur et forme :SolidMasse moléculaire :561.65N-Fmoc-D-glutamine
CAS :N-Fmoc-D-glutamine is Fmoc-protected alpha-glutamine. Alpha-glutamine is an α-amino acid and the most abundant free amino acid in human blood.Formule :C20H20N2O5Degré de pureté :99.14%Masse moléculaire :368.38PROTAC MAGL degrader-1
<p>PROTACMAGLdegrader-1 is an orally active PROTAC agent that simultaneously targets both monoacylglycerol lipase (MAGL) and the E3 ubiquitin ligase MDM2. It functions by degrading MAGL and inhibiting the interaction between MDM2 and p53. Additionally, PROTACMAGLdegrader-1 has partial blood-brain barrier (BBB) penetration and can induce apoptosis in glioblastoma stem cells (GSC).</p>Couleur et forme :Odour SolidSinbaglustat
CAS :<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formule :C11H23NO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :233.3hCYP3A4-IN-1
<p>hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM in</p>Couleur et forme :Odour SolidGalactose 1-phosphate
CAS :<p>Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways</p>Formule :C6H13O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.14(R)-ICMT-IN-3
(R)-ICMT-IN-3 (compound ent 2-27) functions as a potent inhibitor of ICMT, exhibiting an IC50 value of 0.01 μM [1].Couleur et forme :Odour SolidMicafungin metabolite M1
CAS :<p>Micafungin metabolite M1 is an active metabolite of Micafungin, generated through metabolism by arylsulfatase, and exhibits antifungal activity. It can be utilized in research on deep fungal infections caused by Candida species (Candidiasis) and Aspergillus species (Aspergillosis).</p>Formule :C56H71N9O20Couleur et forme :SolidMasse moléculaire :1190.21Desbutyl Lumefantrine
CAS :Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.Formule :C26H24Cl3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.839(S)-HODE cholesteryl ester
CAS :<p>9(S)-HODE cholesteryl ester, from atherosclerotic lesions, has an uncertain origin and serves as a standard for chiral ester analysis.</p>Formule :C45H76O3Couleur et forme :SolidMasse moléculaire :665.1Canine Factor Xa
<p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>Couleur et forme :Odour SolidDihydrozeatin riboside
CAS :<p>Dihydrozeatin riboside is a cytokinin that can be isolated from Phaseolus vulgaris L.</p>Formule :C15H23N5O5Couleur et forme :SolidMasse moléculaire :353.37Pepticinnamin E
CAS :Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor.Formule :C49H54ClN5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :908.43Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Formule :C23H22FN3O5SCouleur et forme :SolidMasse moléculaire :471.12642(±)16-HDHA
CAS :(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495WVSAV
<p>WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.</p>Formule :C27H40N6O7Couleur et forme :SolidMasse moléculaire :560.641-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
CAS :An endogenous blood metabolite, 1-heptadecanoyl-glycerophosphocholine, researches pregnancy/sepsis.Formule :C25H52NO7PCouleur et forme :SolidMasse moléculaire :509.66Diorcinol
CAS :Diorcinol is a natural product that can be used as a reference standard. The CAS number of Diorcinol is 20282-75-1.Formule :C14H14O3Couleur et forme :SolidMasse moléculaire :230.263Acetildenafil
CAS :Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.Formule :C25H34N6O3Couleur et forme :Off-White To Pale Yelow SolidMasse moléculaire :466.58N-Formyl-2-aminophenol
CAS :<p>N-Formyl-2-aminophenol (N-(2-hydroxyphenyl)methanamide) is a bacterial secondary metabolite found in P. chrysogenum and exhibits antioxidant properties.</p>Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.136Rat Factor Xa
<p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>Couleur et forme :Odour SolidLofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Couleur et forme :Odour LiquidBeauveriolide I
CAS :<p>Beauveriolide I, a cyclodepsipeptide from Beauveria, inhibits lipid droplet and cholesterol synthesis in mouse macrophages; IC50=0.78 μM.</p>Formule :C27H41N3O5Couleur et forme :SolidMasse moléculaire :487.635-Formylcytosine
CAS :5-Formylcytosine (5FC) is a rare mammalian DNA base aiding in demethylation, altering helix structure, and affecting RNA polymerase II activity.Formule :C5H5N3O2Couleur et forme :SolidMasse moléculaire :139.11Avenacin A 1
CAS :<p>Avenacin A 1 is a biochemical.</p>Formule :C55H83NO21Couleur et forme :SolidMasse moléculaire :1094.255Laprafylline
CAS :Laprafylline: Xanthine derivative, blocks bronchoconstriction & tumor growth, competes with serotonin, resists histamine at high levels.Formule :C29H36N6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :500.64Rabbit Factor Xa
<p>RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.</p>Couleur et forme :Odour SolidD-(+)-Trehalose-13C12
CAS :<p>D-(+)-Trehalose-13C12 is an isotopic label of D-(+)-Trehalose, enriched with 13C. This compound is pervasively found and often employed as a food ingredient and a shape-forming agent for active molecules.</p>Formule :C12H22O11Couleur et forme :SolidMasse moléculaire :354.216-hydroxy Chlorzoxazone
CAS :<p>6-hydroxy Chlorzoxazone, a chlorzoxazone metabolite, is formed in the liver via CYP2E1.</p>Formule :C7H4ClNO3Couleur et forme :White To PinkMasse moléculaire :185.56tetranor-PGAM
CAS :PGE2 is a biomarker for inflammation and disease; its unstable urinary metabolite, tetranor-PGEM, and its byproduct, tetranor-PGAM, indicate biosynthesis.Formule :C16H22O6Couleur et forme :SolidMasse moléculaire :310.346α-glucosidase/PTP1B-IN-1
α-glucosidase/PTP1B-IN-1 (compound 8a) is an effective inhibitor of both α-glucosidase and PTP1B, with IC50 values of 66.3 μM and 47.0 μM, respectively. It also exhibits strong inhibitory activity against α-amylase, having an IC50 of 30.62 μM. This compound is capable of binding to the active sites of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 holds potential for reducing postprandial blood glucose levels and may be useful in managing type 2 diabetes.Formule :C23H20Cl2O5Couleur et forme :SolidMasse moléculaire :447.31
