Métabolisme
Les inhibiteurs du métabolisme sont des composés qui interfèrent avec les voies métaboliques, modifiant ainsi la production et l'utilisation de l'énergie au sein des cellules. Ces inhibiteurs sont utilisés pour étudier la régulation du métabolisme, le rôle des voies métaboliques dans des maladies telles que le cancer et le diabète, et pour développer de nouvelles stratégies thérapeutiques. Les inhibiteurs du métabolisme peuvent cibler diverses enzymes et processus impliqués dans la glycolyse, l'oxydation des acides gras et d'autres fonctions métaboliques. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de métabolisme de haute qualité pour soutenir vos recherches en biochimie, troubles métaboliques et développement de médicaments.
Sous-catégories appartenant à la catégorie "Métabolisme"
- AhR(42 produits)
- Aminopeptidase(76 produits)
- CETP(20 produits)
- Anhydrase carbonique(196 produits)
- Caséine Kinase(138 produits)
- DHFR(32 produits)
- Décarboxylase(4 produits)
- Déshydrogénase(302 produits)
- FAAH(64 produits)
- FXR(62 produits)
- Facteur Xa(85 produits)
- Synthase des acides gras(37 produits)
- Ferroptose(226 produits)
- GR(3 produits)
- GSNOR(3 produits)
- Glucokinase(57 produits)
- Prolyl-Hydroxylase de HIF/HIF(146 produits)
- HMG-CoA Réductase(34 produits)
- Hydroxylase(36 produits)
- IDO(84 produits)
- LDL(7 produits)
- Lipase(107 produits)
- Lipides(61 produits)
- Lipoxygénase(134 produits)
- MAO(87 produits)
- MPO(2 produits)
- NAMPT(40 produits)
- P450(6 produits)
- PAI-1(26 produits)
- PDE(169 produits)
- PED(1 produits)
- PKM(17 produits)
- PPAR(170 produits)
- Phospholipase(86 produits)
- ROR(47 produits)
- Récepteur de rétinoïdes(22 produits)
- SGK(10 produits)
- Thioredoxine(12 produits)
- Transférase(29 produits)
- Tansporteur(45 produits)
- UGT(4 produits)
- Inhibiteurs de la xanthine oxydase (XO)(9 produits)
Affichez 34 plus de sous-catégories
9182 produits trouvés pour "Métabolisme"
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Boc-Ile-Glu-Gly-Arg-AMC
CAS :Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formule :C34H50N8O10Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :730.81MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45Lantanose A
CAS :Lantanose A is a bioactive chemical from Lantana cumara roots.Formule :C30H52O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :828.72DSPE-PEG1000-APRPG
DSPE-PEG1000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is applicable for drug delivery.Couleur et forme :Odour SolidPoststatin
CAS :Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3.Formule :C26H47N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.69DSPE-PEG2000-APRPG
DSPE-PEG2000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is utilized in drug delivery applications.Couleur et forme :Odour Solid20-hydroxy Leukotriene B4
CAS :20-hydroxy LTB4, a LTB4 metabolite in neutrophils, is less active (~5%) but inhibits LTB4-induced degranulation, retains BLT2 affinity, non-agonist.
Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.471ROC-0929
CAS :ROC-0929 (13a) is a selective sPLA2 inhibitor with IC50 of 80 nM, targeting hGX and blocking ERK1/2, p-38 phosphorylation for inflammation research.Formule :C30H31N3O6SCouleur et forme :SolidMasse moléculaire :561.65Carbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Couleur et forme :Odour SolidCAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662Pestalotin
CAS :Pestalotin, a fungal derivative, promotes rice seedling growth and sugar release, has antifungal properties, and is cytotoxic to certain cells.Formule :C11H18O4Couleur et forme :SolidMasse moléculaire :214.26Lysophosphatidylethanolamines (egg)
CAS :Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine.
Couleur et forme :Solid9(S)-HODE cholesteryl ester
CAS :9(S)-HODE cholesteryl ester, from atherosclerotic lesions, has an uncertain origin and serves as a standard for chiral ester analysis.
Formule :C45H76O3Couleur et forme :SolidMasse moléculaire :665.118-Hydroxycorticosterone
CAS :18-Hydroxycorticosterone is a corticosteroid and corticosterone derivative, which can lead to serious electrolyte imbalances.Formule :C21H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.46Trihydroxycholestanoic Acid
CAS :Trihydroxycholestanoic acid aids cholic acid creation; high levels indicate Zellweger syndrome due to faulty PEX genes.
Formule :C27H46O5Couleur et forme :SolidMasse moléculaire :450.66hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formule :C24H17Cl2N3O3S2Couleur et forme :SolidMasse moléculaire :530.446Plipastatin A1
CAS :Plipastatin A1, a lipopeptide isolated from B.Formule :C72H110N12O20Couleur et forme :SolidMasse moléculaire :1463.71O-Methyl Atorvastatin hemicalcium
CAS :O-Methyl Atorvastatin, an Atorvastatin impurity, orally inhibits HMG-CoA reductase to lower blood lipids.Formule :C68H76CaF2N4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1187.449UDP-glucosamine disodium
CAS :UDP-GlcNAc disodium is a substrate for O-GlcNAc transferase and removed by O-GlcNAcase, produced in the hexosamine pathway regulated by GFAT.Formule :C15H23N3Na2O16P2Couleur et forme :SolidMasse moléculaire :609.28Terpendole I
CAS :Terpendole I, from A. yamanashiensis, inhibits ACAT (IC50=145 μM), fights B. cereus/subtilis (MIC=100 μg/ml), and kills HeLa cells (IC50=52.6 μM).Formule :C27H35NO5Couleur et forme :SolidMasse moléculaire :453.579Calcitroic acid
CAS :Calcitroic acid is a vitamin D receptor (VDR) agonist that activates VDR-mediated transcription. It is the primary metabolite of 1,25-dihydroxyvitamin D3, showing the highest concentrations in the liver and mucosa of mice. The compound exhibits metabolic stability and extremely low toxicity.Formule :C23H34O4Couleur et forme :SolidMasse moléculaire :374.514tetranor-PGAM
CAS :PGE2 is a biomarker for inflammation and disease; its unstable urinary metabolite, tetranor-PGEM, and its byproduct, tetranor-PGAM, indicate biosynthesis.Formule :C16H22O6Couleur et forme :SolidMasse moléculaire :310.346FASN-IN-4 tosylate
CAS :FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Formule :C33H35N3O7S2Couleur et forme :SolidMasse moléculaire :649.78(Rac)-5-Keto Fluvastatin
CAS :(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Formule :C24H24FNO4Degré de pureté :95.04%Couleur et forme :SolidMasse moléculaire :409.452-Pentyl-1H-benzo[d]imidazole
CAS :2-Pentyl-1H-benzo[d]imidazole is a micromolar level inhibitor of Cytochrome P450 1A1 and 2B1 and has antibacterial activity against Fusarium verticillioides.Formule :C12H16N2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :188.27SAICAR
CAS :SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).Formule :C13H19N4O12PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.28Nedosiran sodium
CAS :Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.
Couleur et forme :Solid10(S),17(S)-DiHDHA
CAS :Protectin D1, or neuroprotectin D1 in neurons, is anti-inflammatory. 10(S),17(S)-DiHDHA, also PDX, differs in structure and inhibits neutrophils and platelets.
Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.494α-Amylase-IN-4
α-Amylase-IN-4 (Compd 10y) exhibits the highest level of amylase inhibition, demonstrating an IC50 value of 17.83 ± 0.14 μg/mL [1].Couleur et forme :Odour SolidBeauverolide Ja
CAS :Beauverolide Ja: cyclotetradepsipeptide, CaM inhibitor; Kd 0.078 μM, Ki 0.39 μM; from Isaria fumosorosea.Formule :C35H46N4O5Couleur et forme :SolidMasse moléculaire :602.76Valinotricin
CAS :Valinotricin is a minor fungal metabolite.Formule :C12H22N2O4Couleur et forme :SolidMasse moléculaire :258.31PDE12-IN-1
CAS :PDE12-IN-1, a potent PDE12 inhibitor with a pIC50 of 9.1, increases 2-5A, has a pEC50 of 7.7, and shows antiviral properties.Formule :C31H27BrFN5O3Couleur et forme :SolidMasse moléculaire :616.491Pantothenoylcysteine
CAS :Pantothenoylcysteine is a bioactive chemical.Formule :C12H22N2O6SCouleur et forme :SolidMasse moléculaire :322.38Mycophenolate mofetil hydrochloride
CAS :Mycophenolate Mofetil: Non-competitive, selective inhibitor of IMP dehydrogenase I/II, IC50: 39/27 nM.Formule :C23H32ClNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.96Heptanoyl-L-carnitine (chloride)
CAS :Heptanoyl-L-carnitine is a medium-chain acylcarnitine and derivative of L-carnitine .Formule :C14H28ClNO4Couleur et forme :SolidMasse moléculaire :309.83DSPE-PEG5000-CREKA
DSPE-PEG5000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide is utilized for targeting tumor cells and tumor vasculature, exhibiting anti-tumor activity. DSPE-PEG5000-CREKA is applicable in drug delivery systems.Couleur et forme :Odour SolidAculene A
CAS :Aculene A is a unique type of norsesquiterpene from Aspergillus aculeatus [1] .Formule :C19H25NO3Couleur et forme :SolidMasse moléculaire :315.41Fructosyl-lysine dihydrochloride
CAS :Fructoselysine dihydrochloride, a Maillard reaction product and precursor to diabetes marker glucosepane.Formule :C12H26Cl2N2O7Couleur et forme :SolidMasse moléculaire :381.25DHODH-IN-23
CAS :DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormule :C26H24N6O2Couleur et forme :SolidMasse moléculaire :452.51IDO1-IN-7
CAS :IDO1-IN-7 is a potent IDO1 inhibitor with a 6.1 nM IC50 and immunomodulatory effects for cancer research.Formule :C22H19ClFN3O3Couleur et forme :SolidMasse moléculaire :427.86PKM2-IN-3
CAS :PKM2-IN-3 inhibits PKM2 kinase with 4.1 μM IC50, curbing glycolysis and NLRP3, reducing neuroinflammation.Formule :C21H22O4Couleur et forme :SolidMasse moléculaire :338.4031α-Hydroxy VD4
CAS :1alpha-Hydroxy VD4 can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU, and P31/FUJ cells.Formule :C28H46O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.66PDE1-IN-5
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, ILFormule :C27H29FN4OCouleur et forme :SolidMasse moléculaire :444.54(+)-Geodin
CAS :(+)-Geodin, a fungal metabolite, boosts fibrinolysis in BAECs (50-150 μM) and glucose uptake in rat adipocytes (1-100 μg/ml).Formule :C17H12Cl2O7Couleur et forme :SolidMasse moléculaire :399.18(±)14(15)-EpEDE
CAS :8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid , is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action ofFormule :C20H34O3Couleur et forme :SolidMasse moléculaire :322.489DOTA-XYIMSR-01
CAS :DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57cis-5-Tetradecenoic acid
CAS :cis-5-Tetradecenoic acid, found in blood, helps study Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency.Formule :C14H26O2Couleur et forme :SolidMasse moléculaire :226.36TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.47DSPE-PEG1000-CREKA
DSPE-PEG1000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide has the capability to target tumor cells and tumor vasculature, exhibiting anti-tumor activity. Additionally, DSPE-PEG1000-CREKA can be utilized for drug delivery.Couleur et forme :Odour Solid
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