Tyrosine Kinase/Adaptateurs
Les inhibiteurs des tyrosines kinases et des adaptateurs sont des composés qui ciblent les tyrosines kinases et leurs protéines adaptatrices associées, jouant des rôles essentiels dans la signalisation cellulaire, la croissance et la différenciation. Ces inhibiteurs sont des outils essentiels dans la recherche sur le cancer, car de nombreuses tyrosines kinases sont impliquées dans les voies de signalisation qui favorisent la croissance tumorale et les métastases. En inhibant les tyrosines kinases, ces composés peuvent bloquer des cascades de signalisation cruciales, offrant ainsi des stratégies thérapeutiques potentielles pour divers cancers et autres maladies impliquant une signalisation cellulaire anormale. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de tyrosines kinases et d'adaptateurs de haute qualité pour soutenir vos recherches en oncologie, biologie moléculaire et développement de thérapies ciblées.
Sous-catégories appartenant à la catégorie "Tyrosine Kinase/Adaptateurs"
- ALK(112 produits)
- CSF-1R(42 produits)
- EGFR(572 produits)
- Récepteur Ephrin(23 produits)
- FLT(92 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(170 produits)
- SON(5 produits)
- Hck(3 produits)
- IGF-1R(86 produits)
- PDGFR(126 produits)
- PYK2(7 produits)
- Src(78 produits)
- Récepteur TAM(32 produits)
- Tie-2(20 produits)
- Récepteur Trk(59 produits)
- Tyrosine Kinases(27 produits)
- VEGFR(268 produits)
- c-Fms(108 produits)
- c-Kit(101 produits)
- c-Met/HGFR(128 produits)
- c-RET(51 produits)
Affichez 13 plus de sous-catégories
1375 produits trouvés pour "Tyrosine Kinase/Adaptateurs"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
EGFR-IN-129
<p>EGFR-IN-129 (Compound 10b) is an effective, selective EGFR inhibitor with an IC50 of 51.2 nM and demonstrates broad-spectrum antiproliferative activity against the NCI tumor panel.</p>Formule :C21H18N4O3SCouleur et forme :SolidMasse moléculaire :406.46Cofetuzumab
CAS :<p>Cofetuzumab (PF-06523435) is a antibody targeting protein tyrosine kinase 7 (PTK7), which can be used to synthesize ADC compounds like cofetuzumab pelidotin.</p>Degré de pureté :>95%Couleur et forme :LiquidDS06652923
<p>DS06652923 is an orally active inhibitor targeting EGFR triple mutations. It exhibits growth-inhibitory effects on Ba/F3EGFRdel19/T90M/C795S cells, with a GI50 value of 9.4 nM. Additionally, DS06652923 induces tumor regression in the Ba/F3 syngeneic transplantation model.</p>Couleur et forme :Odour SolidU3-1565
<p>U3-1565 (Anti-HB-EGF antibody) is an antibody targeting HB-EGF with potential anti-tumor activity, used in the study of advanced solid tumors.</p>Couleur et forme :LiquidMasse moléculaire :144.82 kDa (Predicted)MS9427
CAS :<p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>Formule :C48H58ClFN8O12Couleur et forme :SolidMasse moléculaire :993.47Zenocutuzumab
CAS :<p>Zenocutuzumab (MCLA-128) is a humanized antibody targeting HER2, used for research on tumors driven by NRG1 gene rearrangement.</p>Degré de pureté :97%Couleur et forme :LiquidTimigutuzumab
CAS :<p>Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].</p>Couleur et forme :LiquidIGF-I (30-41)
CAS :<p>IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).</p>Formule :C51H83N19O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1266.34Gefitinib N-oxide hydrochloride
<p>Gefitinib N-oxide hydrochloride is an N-oxide of EGFR inhibitor Gefitinib with IC50 of 2-37 nM.</p>Formule :C22H24ClFN4O41·5HClCouleur et forme :SolidMasse moléculaire :517.59KRAS G12D inhibitor 25
CAS :<p>KRAS G12D inhibitor 25 (Compound 148) acts as an inhibitor for KRAS G12C and HSP90α, displaying IC50 values of <0.1 μM and 0.1-1 μM respectively. Additionally, it suppresses the proliferation of MIA PaCa-2 and NCI-H358 cell lines, with EC50 values of <0.1 μM and 0.1-1 μM correspondingly. This compound also promotes the degradation of ERBB2, exhibiting a DC50 of 0.1-1 μM.</p>Formule :C56H62ClN11O6Couleur et forme :SolidMasse moléculaire :1020.62Proinsulin C-peptide (human)
CAS :<p>C-peptide, a 31-amino acid, links Proinsulin A & B chains for correct folding and function.</p>Formule :C129H211N35O48Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3020.26Fosgonimeton acetate
<p>Fosgonimeton acetate is an agonist of hepatocyte growth factor (HGF).</p>Formule :C29H49N4O10PDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :644.69SJF 1521
CAS :<p>SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.</p>Formule :C57H61ClFN7O9SDegré de pureté :99.20%Couleur et forme :SolidMasse moléculaire :1074.65CN009543V
CAS :<p>CN009543V is an enhancer of tyrosine phosphorylation of EGFR via downstream signaling pathways.</p>Formule :C12H12N4O6SCouleur et forme :SolidMasse moléculaire :340.31GIP (3-42), human acetate
<p>GIP (3-42), human acetate is an antagonist of a glucose-dependent insulinotropic polypeptide (GIP) receptor and regulates insulin secretion and GIP metabolism</p>Degré de pureté :98%Couleur et forme :Liquid3-Hydroxy Midostaurin
CAS :<p>3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM in</p>Formule :C35H30N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.648Eflapegrastim
CAS :<p>Eflapegrastim: humanized IgG4 antibody and G-CSF that boosts neutrophils and shortens neutropenia.</p>Couleur et forme :LiquidDepatuxizumab MMAF
<p>Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized in glioblastoma research.</p>Couleur et forme :LiquidMasse moléculaire :148.24 kDaAMG-820
<p>AMG-820 is a human antibody targeting CSF-1R, inhibiting the binding of ligands CSF1 and IL34, and preventing subsequent ligand-induced receptor activation. For AMG-820's isotype control, refer to [Human IgG2 kappa, Isotype Control].</p>Couleur et forme :Odour LiquidcFMS Receptor Inhibitor IV
CAS :<p>cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.</p>Formule :C22H26N4O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :378.47Anti-ERBB3/HER3 (29Z6)
<p>Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor targeting human ERBB3/HER3.</p>Couleur et forme :Odour LiquidARRY-380 (analog )
CAS :<p>ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.</p>Formule :C29H27N7O4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :569.63BMS-777607
CAS :<p>BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.</p>Formule :C25H19ClF2N4O4Degré de pureté :98.16% - 98.56%Couleur et forme :SolidMasse moléculaire :512.89Matuzumab
CAS :<p>Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to study non-small cell lung cancer.</p>Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.9 kDaCetuximab (PBS)
<p>Cetuximab (PBS) is a human IgG1 monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), with a dissociation constant (Kd) of 0.201 nM for EGFR as measured by the SPR method. It exhibits potent antitumor activity.</p>Couleur et forme :Odour LiquidModotuximab
CAS :<p>Modotuximab (DS 1024) is a humanized antibody targeting EGFR with antitumor activity that accelerates the internalization and degradation of EGFR.</p>Degré de pureté :95.5% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 99.3% (SEC-HPLC)Couleur et forme :LiquidBMS-599626
CAS :<p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>Formule :C27H27FN8O3Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :530.55VEGFR-2-IN-55
<p>VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.</p>Couleur et forme :Odour SolidErlotinib-d6
CAS :<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Formule :C22H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.47(3S,4S)-PF-06459988
CAS :<p>(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.</p>Formule :C19H22ClN7O3Couleur et forme :SolidMasse moléculaire :431.88SB-505124
CAS :Formule :C20H21N3O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalineMasse moléculaire :335.41SYN1143
CAS :<p>SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.</p>Formule :C31H29FN4O5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :556.58Tucatinib hemiethanolate
CAS :<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Formule :C54H54N16O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :1007.11CL-387785
CAS :Formule :C18H13BrN4ODegré de pureté :>98.0%(GC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :381.23Lapatinib Ditosylate
CAS :Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :925.46Trapidil
CAS :Formule :C10H15N5Degré de pureté :>98.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :205.27MNS
CAS :Formule :C9H7NO4Degré de pureté :>98.0%(GC)Couleur et forme :Light yellow to Yellow to Green powder to crystalMasse moléculaire :193.16AP23846
CAS :<p>AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.</p>Formule :C24H34N5OPDegré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :439.53PD 173074
CAS :Formule :C28H41N7O3Degré de pureté :>95.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :523.68EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
<p>EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.1-Naphthyl PP1
CAS :Formule :C19H19N5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :317.40EGFRVIII Protein, Human, Recombinant (His & Avi)
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.AG 1478 Hydrochloride
CAS :Formule :C16H14ClN3O2·HClDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :352.22EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :60-90 KDa (reducing condition)EGFR vIII Protein, Human, Recombinant (His)
<p>EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :61-75 Kda (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted)Vatalanib Succinate
CAS :Formule :C20H15ClN4·C4H6O4Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :464.91Rilematovir
CAS :<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Formule :C21H20ClF3N4O3SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :500.92EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-78 kDa based on Tris-Bis PAGE result.Tyrphostin AG 1478
CAS :Formule :C16H14ClN3O2Degré de pureté :>98.0%(HPLC)Couleur et forme :Light orange to Yellow to Green powder to crystalMasse moléculaire :315.76SU 5416
CAS :Formule :C15H14N2ODegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :238.29PD-161570
CAS :Formule :C26H35Cl2N7ODegré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :532.51EGFR vIII Protein, Human, Recombinant (hFc)
<p>EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :90-120 KDa (reducing condition)AEE 788
CAS :Formule :C27H32N6Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :440.60EGFR Protein, Human, Recombinant (His & Avi)
<p>EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.EGFR Protein, Rhesus macaque, Recombinant (His)
<p>EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.PF-06737007
CAS :<p>PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).</p>Formule :C25H28F4N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.49Tyrphostin RG 14620
CAS :Formule :C14H8Cl2N2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :275.13Anti-Src Antibody (1E789)
<p>Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.</p>Couleur et forme :Odour LiquidAnti-EGFR Antibody (3B845)
<p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>Couleur et forme :Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
<p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>Couleur et forme :Odour LiquidAnti-EGFR Antibody (7X976)
<p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>Couleur et forme :Odour LiquidAnti-EGFR Antibody (9S619)
<p>Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.</p>Couleur et forme :Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
<p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>Couleur et forme :Odour LiquidSU 1498
CAS :Formule :C25H30N2O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :390.53Mubritinib
CAS :Formule :C25H23F3N4O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Gray to Brown powder to crystalMasse moléculaire :468.48NSC 12
CAS :<p>NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.</p>Formule :C24H34F6O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :484.52DT-3 acetate
<p>DT-3 acetate is a cell-permeable peptide that acts as an inhibitor of protein kinase G (PKGIα), effectively blocking the cGMP-PKG signaling pathway.</p>Formule :C152H258N52O28S·xC2H4O2Couleur et forme :SolidMasse moléculaire :3294.07 (free acid)Bosutinib
CAS :Formule :C26H29Cl2N5O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :530.45AG-1296
CAS :Formule :C16H14N2O2Degré de pureté :>98.0%(GC)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :266.30PP 1
CAS :Formule :C16H19N5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :281.36Neratinib
CAS :Formule :C30H29ClN6O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :557.05Rociletinib hydrobromide
CAS :<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Formule :C27H29BrF3N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :636.46PD 158780
CAS :Formule :C14H12BrN5Degré de pureté :>97.0%(HPLC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :330.19Pazopanib
CAS :Formule :C21H23N7O2SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :437.52Motesanib
CAS :Formule :C22H23N5ODegré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :373.46Canertinib
CAS :Formule :C24H25ClFN5O3Degré de pureté :>98.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :485.94Cediranib
CAS :Formule :C25H27FN4O3Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :450.51Vandetanib
CAS :Formule :C22H24BrFN4O2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :475.36BAY-826
CAS :<p>BAY-826 is a novel, potent and selective TIE-2 inhibitor that inhibits TIE-2 phosphorylation and can be used to study tumors.</p>Formule :C26H19F5N6OSDegré de pureté :98% - 99.28%Couleur et forme :SolidMasse moléculaire :558.53Sunitinib Malate
CAS :Formule :C22H27FN4O2·C4H6O5Degré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Brown powder to crystalMasse moléculaire :532.57Imatinib Mesylate
CAS :Formule :C29H31N7O·CH4O3SDegré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :589.72SB-525334
CAS :Formule :C21H21N5Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :343.43PLX647
CAS :<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Formule :C21H17F3N4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :382.38Nintedanib
CAS :Formule :C31H33N5O4Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Yellow to Yellow green powder to crystalMasse moléculaire :539.64Linifanib
CAS :Formule :C21H18FN5ODegré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :375.41PF-04217903 methanesulfonate
CAS :<p>PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).</p>Formule :C20H20N8O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.49GDC-0834
CAS :<p>GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and</p>Formule :C33H36N6O3SCouleur et forme :SolidMasse moléculaire :596.74Mavelertinib
CAS :<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Formule :C18H22FN9O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :415.42AV-412 free base
CAS :<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Formule :C27H28ClFN6OCouleur et forme :SolidMasse moléculaire :507Neratinib maleate
CAS :<p>Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.</p>Formule :C34H33ClN6O7Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :673.11N-Desethyl Sunitinib
CAS :<p>N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,</p>Formule :C20H23FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.42Lanraplenib succinate
CAS :<p>Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.</p>Formule :C58H68N18O14Couleur et forme :SolidMasse moléculaire :1241.294SB1317
CAS :<p>SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).</p>Formule :C23H24N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :372.46BPR1K871
CAS :<p>BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of</p>Formule :C25H28ClN7O2SCouleur et forme :SolidMasse moléculaire :526.05Osimertinib dimesylate
CAS :<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Formule :C30H41N7O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :691.82SU14813 maleate
CAS :<p>SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).</p>Formule :C27H31FN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.56BI-4142
CAS :<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Formule :C28H27N9O2Degré de pureté :97.21% - 98.09%Couleur et forme :SolidMasse moléculaire :521.57Cediranib Maleate
CAS :Formule :C25H27FN4O3·C4H4O4Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :566.59JK-P3
CAS :Formule :C18H17N3O3Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :323.35Saracatinib
CAS :Formule :C27H32ClN5O5Degré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :542.03Tyrphostin AG 879
CAS :Formule :C18H24N2OSDegré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange powder to crystalMasse moléculaire :316.46trans-Pralsetinib
CAS :<p>trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).</p>Formule :C27H32FN9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.6Nilotinib
CAS :Formule :C28H22F3N7ODegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :529.53PD 0325901
CAS :Formule :C16H14F3IN2O4Degré de pureté :>97.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :482.20DDR1-IN-4
CAS :<p>DDR1-IN-4 is a DDR1 inhibitor that inhibits autophosphorylation of DDR1 and DDR2 and can be used to study chronic kidney disease.</p>Formule :C23H20BrF3N6O3Degré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :565.34PQ401
CAS :Formule :C18H16ClN3O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :341.80Hypericin
CAS :Formule :C30H16O8Degré de pureté :>95.0%(HPLC)Couleur et forme :Black powder to crystalMasse moléculaire :504.45A-770041
CAS :<p>A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.</p>Formule :C34H39N9O3Degré de pureté :99.23% - 99.86%Couleur et forme :SolidMasse moléculaire :621.73Pazopanib Hydrochloride
CAS :Formule :C21H23N7O2S·HClDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :473.98HNMPA-(AM)3
CAS :<p>HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。</p>Formule :C20H23O10PDegré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :454.36WHI-P180 Hydrochloride
CAS :Formule :C16H15N3O3·HClDegré de pureté :>97.0%(T)(HPLC)Couleur et forme :White to Light gray to Light yellow powder to crystalMasse moléculaire :333.77PP 2
CAS :Formule :C15H16ClN5Degré de pureté :>97.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :301.78Regorafenib
CAS :Formule :C21H15ClF4N4O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :482.82SM27
CAS :<p>SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.</p>Formule :C21H16N2O9S2Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :504.49Tyrphostin A9
CAS :Formule :C18H22N2ODegré de pureté :>98.0%(GC)Couleur et forme :Light orange to Yellow to Green powder to crystalMasse moléculaire :282.39WHI-P154
CAS :Formule :C16H14BrN3O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :376.21Tyrphostin 8
CAS :<p>Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein</p>Formule :C10H6N2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :170.17Daphnetin
CAS :Formule :C9H6O4Degré de pureté :>90.0%(HPLC)Couleur et forme :White to Light yellow to Light red powder to crystalMasse moléculaire :178.14BMS-599626
CAS :Formule :C27H27FN8O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :530.56Brivanib
CAS :<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Formule :C19H19FN4O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :370.38Tyrphostin RG 13022
CAS :Formule :C16H14N2O2Degré de pureté :>98.0%(GC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :266.30Anti-EGFR Monoclonal Antibody-Biotin
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Degré de pureté :> 95% as determined by SDS-PAGE.Couleur et forme :LiquidMasse moléculaire :150 kDaAnti-EGFR Monoclonal Antibody
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Degré de pureté :> 95% as determined by SDS-PAGE.Couleur et forme :LiquidMasse moléculaire :150 kDaNaquotinib
CAS :<p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>Formule :C30H42N8O3Degré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :562.71(Rac)-IBT6A
CAS :<p>(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>Formule :C22H22N6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :386.45squarunkinA
CAS :<p>squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-</p>Formule :C25H32F3N5O4Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :523.55LY2874455
CAS :<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Formule :C21H19Cl2N5O2Degré de pureté :97.22% - 99.46%Couleur et forme :SolidMasse moléculaire :444.31Protein kinase inhibitors 1
CAS :<p>Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.</p>Formule :C18H17N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :383.42Bacitracin Zinc
CAS :<p>Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.</p>Formule :C66H101N17O16SZnDegré de pureté :63.98%Couleur et forme :Light-Colored Free-Flowing PowdersMasse moléculaire :1486.07ZM39923 hydrochloride
CAS :<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91Malantide acetate(86555-35-3 free base)
<p>Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide</p>Formule :C74H128N22O23Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :1693.97R-268712
CAS :<p>R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.</p>Formule :C20H18FN5ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :363.39ASP5878
CAS :<p>ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.</p>Formule :C18H19F2N5O4Degré de pureté :99.8% - 99.89%Couleur et forme :SolidMasse moléculaire :407.37PP 3
CAS :<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Formule :C11H9N5Degré de pureté :98.61%Couleur et forme :Whit To Off-White SolidMasse moléculaire :211.22BMS-911543
CAS :<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Formule :C23H28N8ODegré de pureté :97.69% - 99.98%Couleur et forme :SolidMasse moléculaire :432.52Ningetinib Tosylate
CAS :<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formule :C38H37FN4O8SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :728.79LDN193189
CAS :<p>LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.</p>Formule :C25H22N6Degré de pureté :98% - 99.86%Couleur et forme :SolidMasse moléculaire :406.48FLT3-IN-2
CAS :<p>FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).</p>Formule :C21H16ClF3N4Degré de pureté :97.57% - 98.53%Couleur et forme :SolidMasse moléculaire :416.83Glumetinib
CAS :<p>Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).</p>Formule :C21H17N9O2SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :459.48Fostamatinib Disodium
CAS :<p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>Formule :C23H24FN6O9P·2NaDegré de pureté :96.13% - 99.09%Couleur et forme :SolidMasse moléculaire :624.42AAL-993
CAS :<p>AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.</p>Formule :C20H16F3N3ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :371.36MSDC 0160
CAS :<p>MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.</p>Formule :C19H18N2O4SDegré de pureté :98.11% - 99.53%Couleur et forme :SolidMasse moléculaire :370.42BIBF0775
CAS :<p>BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).</p>Formule :C31H34N4O2Degré de pureté :99.45% - 99.79%Couleur et forme :SolidMasse moléculaire :494.63Ruxolitinib (S enantiomer)
CAS :<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Formule :C17H18N6Degré de pureté :99.37% - 99.79%Couleur et forme :SolidMasse moléculaire :306.36AZ7550
CAS :<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formule :C27H31N7O2Degré de pureté :97.07% - 99.75%Couleur et forme :SolidMasse moléculaire :485.58Tyrphostin AG 528
CAS :<p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>Formule :C18H14N2O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :306.32JCN037
CAS :<p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>Formule :C16H11BrFN3O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :376.185'-Fluoroindirubinoxime
CAS :<p>5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).</p>Formule :C16H10FN3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :295.27FIIN-3
CAS :<p>FIIN-3 is an irreversible inhibitor of FGFR.</p>Formule :C34H36Cl2N8O4Degré de pureté :97.63% - 98.92%Couleur et forme :SolidMasse moléculaire :691.61Osimertinib mesylate
CAS :<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Formule :C29H37N7O5SDegré de pureté :99.46% - >99.99%Couleur et forme :SolidMasse moléculaire :595.71GSK1838705A
CAS :<p>GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.</p>Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.57Tyrphostin A9
CAS :<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Formule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38Dovitinib lactate
CAS :<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Formule :C24H27FN6O4Degré de pureté :99.54% - 99.77%Couleur et forme :SolidMasse moléculaire :482.51Neratinib
CAS :<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04(E/Z)-Zotiraciclib
CAS :<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46(E)-AG 99
CAS :<p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>Formule :C10H8N2O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :204.18Entrectinib
CAS :<p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Formule :C31H34F2N6O2Degré de pureté :98.03% - 99.61%Couleur et forme :SolidMasse moléculaire :560.64AG-494
CAS :<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28CP-724714
CAS :<p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>Formule :C27H27N5O3Degré de pureté :97.1% - 98.82%Couleur et forme :SolidMasse moléculaire :469.54HPK1-IN-2
CAS :<p>HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.</p>Formule :C19H20N6OSDegré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :380.47RG14620
CAS :<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Formule :C14H8Cl2N2Degré de pureté :99.82% - 99.87%Couleur et forme :SolidMasse moléculaire :275.13UNC2541
CAS :<p>UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.</p>Formule :C24H34FN7O2Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :471.57AG-13958
CAS :<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Formule :C26H22FN7ODegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :467.5G5-7
CAS :<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39AZD8931 diFuMaric acid
CAS :<p>AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).</p>Formule :C31H33ClFN5O11Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :706.1Theliatinib
CAS :<p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>Formule :C25H26N6O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :442.51Theliatinib tartrate
CAS :<p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.</p>Formule :C29H32N6O8Couleur et forme :SolidMasse moléculaire :592.6Decernotinib
CAS :<p>Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.</p>Formule :C18H19F3N6ODegré de pureté :99.28% - >99.99%Couleur et forme :SolidMasse moléculaire :392.38RepSox
CAS :<p>RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).</p>Formule :C17H13N5Degré de pureté :98.8% - 99.73%Couleur et forme :SolidMasse moléculaire :287.32LDN-214117
CAS :<p>LDN-214117 is a potent and selective ALK2 inhibitor.</p>Formule :C25H29N3O3Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :419.52SU5205
CAS :<p>SU5205 is a VEGFR2 inhibitor.</p>Formule :C15H10FNODegré de pureté :99.62% - 99.67%Couleur et forme :SolidMasse moléculaire :239.24R112
CAS :<p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :SolidMasse moléculaire :312.3TL-895
CAS :<p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>Formule :C25H26FN5O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :447.5NRC-2694
CAS :<p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>Formule :C24H26N4O3Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :418.49SYR127063
CAS :<p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>Formule :C23H20ClF3N4O3Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :492.88SCR-1481B1
CAS :<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Formule :C32H40ClF2N6O13PDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :821.12Ponatinib
CAS :<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Formule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56Dacomitinib
CAS :<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Formule :C24H25ClFN5O2Degré de pureté :99.4% - 99.72%Couleur et forme :SolidMasse moléculaire :469.94Oritinib mesylate
CAS :<p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>Formule :C32H41N7O5SCouleur et forme :SolidMasse moléculaire :635.78Pralsetinib
CAS :<p>Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T</p>Formule :C27H32FN9O2Degré de pureté :97.88% - 99.8%Couleur et forme :SolidMasse moléculaire :533.6AMG-47a
CAS :<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Remibrutinib
CAS :<p>Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.</p>Formule :C27H27F2N5O3Degré de pureté :99.5% - 99.81%Couleur et forme :SolidMasse moléculaire :507.53LDC1267
CAS :<p>LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).</p>Formule :C30H26F2N4O5Degré de pureté :99.38% - 99.88%Couleur et forme :SolidMasse moléculaire :560.55Vatalanib free base
CAS :<p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>Formule :C20H15ClN4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :346.81ZM 306416
CAS :<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Formule :C16H13ClFN3O2Degré de pureté :99.37% - ≥95%Couleur et forme :SolidMasse moléculaire :333.74Crenolanib
CAS :<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Formule :C26H29N5O2Degré de pureté :98.40% - 99.73%Couleur et forme :SolidMasse moléculaire :443.54AG490
CAS :<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formule :C17H14N2O3Degré de pureté :98.6% - 99.39%Couleur et forme :Yellow SolidMasse moléculaire :294.31-Naphthyl PP1
CAS :<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Formule :C19H19N5Degré de pureté :99.85%Couleur et forme :White Cyrstalline SolidMasse moléculaire :317.39Tolimidone
CAS :<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Formule :C11H10N2O2Degré de pureté :99.85% - 99.85%Couleur et forme :SolidMasse moléculaire :202.21Butein
CAS :<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Formule :C15H12O5Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :272.25Pexmetinib
CAS :<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formule :C31H33FN6O3Degré de pureté :99.07% - 99.66%Couleur et forme :SolidMasse moléculaire :556.63Entospletinib
CAS :<p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>Formule :C23H21N7ODegré de pureté :98.54% - 99.51%Couleur et forme :SolidMasse moléculaire :411.46Fisogatinib
CAS :<p>Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.</p>Formule :C24H24Cl2N4O4Degré de pureté :99.27% - ≥95%Couleur et forme :SolidMasse moléculaire :503.38Chrysophanol
CAS :<p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>Formule :C15H10O4Degré de pureté :99.44% - 99.91%Couleur et forme :Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CMasse moléculaire :254.24DMH-1
CAS :<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Formule :C24H20N4ODegré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :380.44Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71CH5424802 analog
CAS :<p>CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.</p>Formule :C28H30N4O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :454.56
