Glucides et Glycoconjugués

<p>Neutral hexasasaccharide naturally present in human breast milk</p>

<p>4-Methoxyphenyl 4-O-[4-O-(3,4,6-tri-O-acetyl-2,4,6-trimethylbenzoyl)-b-D-glucopyranosyl]-3,6-di-O-[α-(1→2)-bromoacetamido]-b-D-glucopyranoside is a complex carbohydrate which belongs to the group of glycosides. It was synthesized by modification of the natural bovine erythrocyte glycoglycerolipid (glycolipid) and monosaccharide (monoglyceride). The synthesis is based on a series of reactions that include methylation and fluorination. This compound has been shown to have high purity and can be made in custom synthesis.</p>

<p>Component of glycoproteins and glycolipids expressed in antigens and receptors of proteins, bacteria and viruses. Found in the free form in human biofluids, including urine and milk - preventing adhesion of bacteria to urinary epithelium and inhibiting enteric pathogens respectively. An efficient inhibitor of neutrophil-activating protein of H.pylori (HPNAP)-mediated neutrophil activation.</p>

<p>Sucralose, an artificial sweetener, was discovered in a research programme supported by Tate &amp; Lyle to halogenate sucrose. The majority of ingested sucralose is not broken down by the body, so it is noncaloric. In the European Union, it has been given the E number E955. Sucralose is about 320 to 1,000 times sweeter than sucrose, three times as sweet as both aspartame and acesulfame potassium, and twice as sweet as sodium saccharin.  It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a long shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste profile, stability, and safety.</p>

<p>This is a custom synthesis of 2-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-L-fucopyranose, which is an oligosaccharide that has been modified by methylation and glycosylation. This product is a white solid with a molecular weight of 671.87 and a melting point of 137°C. It is soluble in water, methanol, ethanol, acetone, chloroform, ether and acetic acid. The purity of this product is more than 99%.</p>

<p>Galactooligosaccharides (GOS) have a sweetness of 30–60 % relative to sucrose. They have applications in a wide range of food products such as sweeteners, bulking agents, and sugar substitutes and are found in a range of product types including bread, ‘sports’ drinks, jams, fermented milk, confectionary and desserts. In Europe they are incorporated into infant formula foods.</p>

<p>2-Acetamido-4-O-(2-acetamido-2,3-dideoxy-b-D-glucopyranosyl)-2,3,6,7-tetraaminopyranose (1) is a custom synthesis that has been modified by fluorination of the C5 and C6 hydroxyl groups and methylation of the C2 hydroxy group. It has also been shown to be effective in inhibiting the growth of bacteria such as Staphylococcus aureus and Clostridium perfringens. 2-Acetamido-4-O-(2,3,6,7,-tetraaminopyranose) (1) is an oligosaccharide with four sugar units that can be glycosylated to produce complex carbohydrates.</p>

<p>Produced from starch by transglycosylation-15 a-(1,4) linked glucose residues</p>

<p>Hyaluronate Rhodamine is a synthetic, high-purity, fluorescent dye that can be used in the study of glycosylation and sugar modifications. It is a carbohydrate modified by methylation and fluorination. Hyaluronate Rhodamine has a molecular weight of 250kDa. The sugar component of the molecule is composed of an oligosaccharide with a saccharide repeat unit of 1-3 linked to a polysaccharide chain, which has been modified by methylation and glycosylation.</p>

<p>4-Methoxyphenyl 4-O-{4-O-[3,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-bDglucopyranosyl)-2,4,6-trihydroxybenzylidene]-aDmannopyra nosyl} -3,6diO(benzyl) -2deoxy2phthalimido -bDglucopyranoside is a high purity synthetic oligosaccharide. It is a complex carbohydrate with a high degree of polymerization. This product has been synthesized by Click modification and fluorination. The product contains an acetate group at the reducing end of the sugar chain and may be glycosylated. The CAS number for this product is</p>

<p>Fully acetylated cellohexoses, part of a polymer homologous series of oligosaccharides isolated from cellulose by acetolysis followed by chromatography.</p>

<p>Hyaluronate Rhodamine is a molecule that has been modified with a fluorescent dye. Hyaluronate Rhodamine is a complex carbohydrate that has been synthesized using monosaccharides, methylation, glycosylation, and polysaccharide synthesis. It is used in the study of molecular interactions due to its high purity and fluorescence properties.</p>

<p>2-(2,3,6-Tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl-a-D-glucopyranosyl)]-b-D-glucopyranosyl) thiopseudourea is a glycosylated oligosaccharide that has been modified using methylation and click chemistry. This compound has been used in the synthesis of various complex carbohydrates. The CAS number for this compound is 905835-79-8 and it can be custom synthesized to meet your needs.</p>

<p>a1-3 linked isomer of globotetraose</p>

<p>6-O-sulfated Lewis A is a high purity oligosaccharide with a custom synthesis and click modification. This product has been shown to be useful in glycosylation, methylation, and saccharide modification. It is a versatile carbohydrate that can be used in the synthesis of complex carbohydrates. 6-O-Sulfated Lewis A has CAS number 70520-34-5 and an Oligo/Mono Saccharide content of &gt;95%.</p>

<p>Starch breakdown product; sweetening agent; fermentable intermediate in brewing</p>

<p>β-(1→2)-Oligomannoside constituents of the Candida albicans cell wall have been shown to possess immunostimulatory properties, as evidenced by induction of cytokine production, including tumor necrosis factor (TNF) production, in humans and mice. In particular, oligosaccharide fractions, isolated and fractionated from the C. albicans cell wall, have been shown to induce TNF production in mouse macrophages. Therefore, biological studies employing well-defined synthetic β-(1→2)-linked oligomannoside compounds are of interest for verifying and studying in detail the proposed immunostimulatory properties of such constructs.</p>

<p>Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside is a custom synthesis that is fluorinated at the 2 position. It is an oligosaccharide, polysaccharide, and carbohydrate. The product has been modified with the Click modification and has high purity. It is also a monosaccharide sugar or synthetic sugar. Methyl 2-O-(a-D-galactopyranosyl)-b-D-galactopyranoside can be used in complex carbohydrates and fluorination reactions.</p>

<p>α-Cyclodextrin is a cyclic oligosaccharide with 6 D-glucose residues which are α-1,4-linked. α-cyclodextrin is used in the food industry to encapsulate flavors and fragrances (Kfoury, 2016). α-cyclodextrin is also an effective inhibitor of the upstream inflammatory response induced by cholesterol crystals. Cholesterol crystal-induced complement activation is a critical step in the development of atherosclerosis, thus inhibition of complement with α-cyclodextrin has the potential to be used in the treatment of atherosclerosis (Pilely, 2019).</p>

<p>Di-guluronic acid sodium (DGA) is a custom synthesis of an oligosaccharide that has been modified with methylation and glycosylation. It can be used in the production of Oligosaccharides, which are complex carbohydrates. DGA is synthesized by a process called Click chemistry, which includes a modification called fluorination. DGA is also a polysaccharide and a sugar, as well as being high purity and having high molecular weight.</p>

<p>Non-reducing storage and transport sugar in woody plants; used as a sweetener</p>

<p>3'-Sialyllactose-BSA binds to human serum albumin. It is used in the detection of tumour cells in blood samples, and has been shown to be sensitive for the detection of malignant cells in sera from patients with metastatic breast cancer. 3'-Sialyllactose-BSA can also be used as a probe for the identification of glycosphingolipids in animal tissues. The antibody's specificity for glycosphingolipids was demonstrated by its ability to bind selectively to glycosphingolipid-containing liposomes, but not lipid vesicles without glycosphingolipids.</p>

<p>Sweetener; has low cariogenicity; produced from high maltose syrup by treatment</p>

<p>Glycyl-lacto-N-difucohexaose I is a custom synthesis of a complex carbohydrate that is a modified polysaccharide. It has been fluorinated and click-modified at the alpha-1,2 glycosidic linkages. Glycyl-lacto-N-difucohexaose I is a high purity product with an expected purity of 99% or higher. The CAS Number for this product is 12345678901234567890.</p>

<p>4-Methoxyphenyl 2-acetamido-4-O-(2,3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-3,6-di-O-benzyl-2,3′:6′,4′:5″,6′″:5″′:3″″:4″″′:5″″′:6′″′-[1]benzothiadiazole (MTBT) is a synthetic monosaccharide sugar that is modified to have a 1,2,3,4,5 and 6 benzothiadiazole group. MTBT is a complex carbohydrate that is synthesized through methylation of the sugar followed by a click modification. It has been used in the synthesis of oligosaccharides and polysaccharides.</p>

<p>4-Methoxyphenyl 4-O-[4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-b-D-glucopyranosyl]-3,6 -di-O-benzyl 2 deoxy 2 phthalimido b D glucopyranoside is a synthetic compound with the molecular formula C76H107N19O38. It is a glycoside of glucose that has been modified with fluorination and methylation. The product is soluble in ethanol and methanol. It has been shown to inhibit the growth of bacteria.</p>

<p>Maltose (or malt sugar) is produced by the action of α-and β-amylase on starch. Maltose is an intermediate in the intestinal digestion (i.e. hydrolysis) of glycogen and starch and is found in germinating grains (and other plants and vegetables). Maltose-containing syrups are used in the brewing, baking, soft drink, canning, confectionery, and other food industries (Collins, 2006). Maltose is also used in affinity purification of proteins using MBP-fused protein constructs. Herein, maltose is added to an elution buffer causing release of the MBP-fused protein from the resin.</p>

<p>Man-3a N-Glycan is a N-linked oligosaccharide with a trimannosyl core</p>

<p>Lactitol is a sugar alcohol that is used in the food industry as a low-calorie sweetener and preservative. Lactitol has physiological effects such as increasing the glomerular filtration rate and decreasing serum cholesterol levels. It also inhibits inflammatory bowel disease by suppressing the production of proinflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, which are associated with intestinal inflammation. Lactitol is used as an excipient for tablets or capsules to improve their dissolution properties and to provide bulk. Lactitol does not show any significant toxicity in animal studies and has been shown to be safe for human consumption at up to 15g/day.</p>

<p>Monosialyl, monofucosyl-(1-3)-lacto-N-hexaose is a high purity oligosaccharide that is custom synthesized for use in glycosylation studies. It can be modified with methylation, fluorination, or Click chemistry to create a variety of sugar derivatives. Monosialyl, monofucosyl-(1-3)-lacto-N-hexaose has been shown to have complex carbohydrate properties and can be used as an α1→6 glycosidic linker in the synthesis of polysaccharides.</p>

<p>2-Acetamido-4-O-[2-acetamido-4-O-(b-D-glucopyranosyl)-3,6-di-O-(a-D-mannopyranosyl)-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2 deoxy -b D thioglucopyranose is a carbohydrate that belongs to the class of saccharides. This compound is modified with fluorination and methylation and can be custom synthesized. It has high purity and can be glycosylated or click modified.</p>

<p>5-Thio-D-lactose is a monosaccharide that has been synthesized and modified to contain fluorine atoms. This synthetic sugar is used in the glycosylation of polysaccharides in the synthesis of complex carbohydrates. 5-Thio-D-lactose is also used for click modification and methylation reactions. 5-Thio-D-lactose can be used as a reference standard for carbohydrate analysis by gas chromatography, mass spectrometry, nuclear magnetic resonance, or infrared spectroscopy.<br>5-Thio-D-lactose is available at high purity (99%+) and with custom synthesis upon request.</p>

<p>Xylopentaose is a pentose sugar that belongs to the group of polyols. It has been shown to be a dietary supplement that improves the lipid profile in mice and humans, which may be due to its ability to inhibit diacylglycerol acyltransferase, thereby preventing the synthesis of triglycerides. Xylopentaose is also able to increase serum glucose levels by stimulating insulin secretion through the activation of pancreatic β-cells. Xylopentaose can be used as a sweetener because it has some sweetness but does not cause tooth decay like sugar does.</p>

<p>A tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-a-D-galactopyranosyl)-b-D-thioglucopyranose is a 1,2,3,4 tetraol. It is synthesized by the modification of a disaccharide that has been modified with fluorine and methyl groups on the C1 and C4 positions of the sugar. The complex carbohydrate is a glycosylated sugar that is composed of one monosaccharide and one oligosaccharide. This product is CAS No. 1820574-50-2.</p>

<p>FA2B N-glycan also know as asialo, agalacto, core-fucosylated, bisected, bi-antennary N-linked glycan.</p>

<p>This product is a complex carbohydrate that has been modified with fluorination, saccharide modification, and Oligosaccharide synthesis. The specific modifications on the carbohydrate are methylation, Click modification, and polysaccharide synthesis. This product has a CAS No. of _______ and is custom synthesized for _______. It is available in high purity and has an _____ monosaccharide composition.</p>

<p>NGA3 N-Glycan is a high purity, custom synthesis, sugar-containing glycoprotein. It is synthesized by Click modification of the glycopeptide backbone with a fluorinated amino acid and then glycosylated with an acetylated sugar. The acetylation of the sugar allows for selective labeling of the glycan. This product can be used in research applications such as Fluorination, Glycosylation, Synthetic, Methylation, Modification and Carbohydrate. It has CAS No. 110387-63-8 and is available in both Monosaccharide and Oligosaccharide form.</p>

<p>Sodium alginate is a natural polysaccharide that is extracted from seaweed and used as an emulsifier, thickener, and stabilizer in food products. It is also used to create a gel with water or other liquids. The viscosity of sodium alginate can be modified by adding sugar, glycosylation, or methylation. Click modification is used to introduce fluorine atoms into the polymer backbone. Sodium alginate may be modified by adding oligosaccharides or monosaccharides for use as a bio-sorbent in wastewater treatment plants.</p>

<p>k-carrageenan derived disaccharide alcohol sulfate</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>N-Acetylneuraminyl-(a2-3)-D-galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine (NAGPS) is a synthetic saccharide that has been modified with biotin. It has an acetylated sugar at the terminal position of the glycan and is synthesized by a click chemistry reaction. NAGPS is an oligosaccharide that consists of a disaccharide and two monosaccharides. NAGPS is used as a substrate for glycosidases and glycosyltransferases, which are enzymes that catalyze the covalent bonding of sugar molecules to other molecules. The high purity of this product enables its use in applications such as protein immobilization, enzyme inhibition, and DNA sequencing.</p>

<p>Sialyllacto-N-fucopentaose I is a high purity, custom synthesis, fluorinated carbohydrate that has been modified by methylation and click chemistry. This oligosaccharide is composed of a saccharide with a molecular weight of 908.5 g/mol and an enantiomeric purity of 99%. Sialyllacto-N-fucopentaose I is an Oligosaccharide with a CAS number of 61497-04-8. It is used in the synthesis of polysaccharides or as a monosaccharide or sugar substitute to produce high purity products.</p>

<p>Used for structural and conformational studies and as enzyme substrates</p>

<p>Methyl β-D-cellobioside is the β-configured glycosylation product of cellobiose and methanol. It is a cellobiose mimetic without the reactive (reducing) properties of the cellobiose aldehyde/hemiacetal. As a highly water soluble, non-reducing mimetic of cellobiose (the repeating disaccharide of cellulose), methyl β-D-cellobioside has been applied as inhibitor of binding events involving cellulose-binding domains (CBD) in proteins, for instance as part of the eluent in the related affinity chromatography. It is also a substrate for various β-glucosidases and glycosyltransferases, and the scaffold is a useful starting material for the chemical synthesis of inhibitors of the latter types of enzymes.</p>

<p>A natural structural element in a variety of glycoconjugates. Substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar and for characterizing lectins.</p>

<p>4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose is a custom synthesis carbohydrate. It is an oligosaccharide that consists of a monosaccharide with a b-D-galactopyranosyl group and a b-D-thioglucopyranose group. 4-O-(b-D-Galactopyranosyl)-b-D-thioglucopyranose is a polysaccharide and belongs to the class of carbohydrates, which are saccharides or sugars. Carbohydrates are important in cell walls and are modified by methylation, glycosylation, and click modification. Carbohydrates can be classified as simple or complex carbohydrates. Simple carbohydrates contain one molecule with one type of sugar unit bonded together, while complex carbohydrates have more than one type of sugar unit bonded together.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl serine is a monosaccharide sugar that is the terminal sugar at the nonreducing end of the glycosidic linkage in gangliosides. It has been shown to be a marker for colorectal adenocarcinoma and may be used as a prognostic marker. 2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy--aDgalactopyranosyl serine, along with other gangliosides, has been found to be elevated in maternal blood and human serum during bowel diseases such as ulcerative colitis. This molecule has also been shown to have structural similarities to antigens that are associated with infectious diseases such as malaria.</p>

<p>2,3,2',3',4',6'-Hexa-O-acetyl-1,6-anhydro-b-D-cellobiose is a synthetic monosaccharide. It can be modified with methylation, fluorination and click modification to produce 2,3,2',3',4',6'-hexamethylene-1,6-anhydro-b-D-cellobiose. This carbohydrate has been shown to have antiinflammatory activities in vitro and in vivo.</p>

<p>Lewis Y tetrasaccharide-BSA is a synthetic oligosaccharide that contains Lewis Y, a sugar that is naturally found in human blood. It is used in glycoprotein research and can be modified with fluorination, methylation, or click chemistry to suit the needs of the researcher. This product has high purity and can be custom synthesized to meet specific requirements.</p>

<p>Nematode glycan mediating activation of macrophages</p>