Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(113 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(65 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6107 prodotti di "Apoptosi"
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Sulforaphane
CAS:Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H11NOS2Purezza:95% - 99.79%Colore e forma:Light Yellow LiquidPeso molecolare:177.29Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurezza:98% - 99.87%Colore e forma:SolidPeso molecolare:532.61PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurezza:95.49% - 99.16%Colore e forma:SolidPeso molecolare:328.29Ref: TM-T3105
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg170,00€50mg259,00€100mg409,00€1mL*10mM (DMSO)73,00€Picropodophyllin
CAS:Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.Formula:C22H22O8Purezza:98.38% - 99.83%Colore e forma:SolidPeso molecolare:414.41Ref: TM-T6943
5mg64,00€10mg88,00€25mg170,00€50mg316,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)69,00€β-Elemonic Acid
CAS:β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.Formula:C30H46O3Purezza:99.61% - 99.8%Colore e forma:SolidPeso molecolare:454.68Ref: TM-T2S0618
1mg35,00€5mg75,00€10mg110,00€25mg192,00€50mg286,00€100mg425,00€200mg612,00€1mL*10mM (DMSO)84,00€Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Formula:C17H16O4Purezza:99.18% - 99.35%Colore e forma:Less Transparent Liquid Colorless Transparent LiquidPeso molecolare:284.31Levomenol
CAS:Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.Formula:C15H26OPurezza:96.01%Colore e forma:Clear To Yellowish LiquidPeso molecolare:222.37Pevonedistat
CAS:Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).Formula:C21H25N5O4SPurezza:95% - 99.92%Colore e forma:SolidPeso molecolare:443.52Ref: TM-T6332
1mg50,00€2mg66,00€5mg90,00€10mg137,00€25mg245,00€50mg401,00€100mg680,00€1mL*10mM (DMSO)88,00€Onatasertib
CAS:Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formula:C21H27N5O3Purezza:99.14% - 99.93%Colore e forma:SolidPeso molecolare:397.47PIK-75
CAS:PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formula:C16H14BrN5O4SPurezza:98.52% - >99.99%Colore e forma:SolidPeso molecolare:452.28Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purezza:98.20% - 99.36%Colore e forma:White To Off-White SolidPeso molecolare:459.92,4,6-Triiodophenol
CAS:2,4,6-Triiodophenol: iodinated byproduct from sewage chlorination, disrupts thyroid function, used to study deiodinase.Formula:C6H3I3OPurezza:98.11%Colore e forma:Grey To Tan To Brown PowderPeso molecolare:471.81400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Formula:C10H17Cl2N3Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:250.17Ref: TM-T3491
5mg48,00€10mg71,00€25mg118,00€50mg207,00€100mg354,00€200mg460,00€500mg747,00€1mL*10mM (DMSO)50,00€2-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purezza:98% - 99.95%Colore e forma:Off-White SolidPeso molecolare:302.41GW 5074
CAS:GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.Formula:C15H8Br2INO2Purezza:99.32%Colore e forma:SolidPeso molecolare:520.94WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purezza:98% - 99.67%Colore e forma:SolidPeso molecolare:376.2S63845
CAS:S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.Formula:C39H37ClF4N6O6SPurezza:97.7% - ≥98%Colore e forma:SolidPeso molecolare:829.26Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formula:C15H10Cl2N2O2SPurezza:96.57% - 99.23%Colore e forma:SolidPeso molecolare:353.22Ref: TM-T1907
5mg44,00€10mg52,00€25mg95,00€50mg144,00€100mg215,00€200mg319,00€500mg530,00€1mL*10mM (DMSO)48,00€Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purezza:97.03% - 99.99%Colore e forma:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Peso molecolare:324.42PYR-41
CAS:PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.Formula:C17H13N3O7Purezza:98.25%Colore e forma:SolidPeso molecolare:371.3Ref: TM-T6629
2mg37,00€5mg54,00€10mg82,00€25mg154,00€50mg294,00€100mg447,00€200mg618,00€500mg973,00€1mL*10mM (DMSO)60,00€Lupeol
CAS:Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.Formula:C30H50OPurezza:98% - 99.96%Colore e forma:Needles From Alcohol Acetone White PowderPeso molecolare:426.72Purvalanol A
CAS:Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formula:C19H25ClN6OPurezza:98.13% - 99.68%Colore e forma:PowderPeso molecolare:388.89Meisoindigo
CAS:Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).Formula:C17H12N2O2Purezza:98.03% - 98.19%Colore e forma:SolidPeso molecolare:276.29Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:212.24M50054
CAS:Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.Formula:C13H16O4Purezza:97.8%Colore e forma:SolidPeso molecolare:236.26BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purezza:97.13% - 97.54%Colore e forma:SolidPeso molecolare:464.56BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purezza:98% - 99.88%Colore e forma:SolidPeso molecolare:521.65Ref: TM-T6173
1mg43,00€2mg56,00€5mg93,00€10mg98,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€1mL*10mM (DMSO)92,00€Copanlisib
CAS:Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.Formula:C23H28N8O4Purezza:99% - 99.88%Colore e forma:SolidPeso molecolare:480.52Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35Ref: TM-T6S0117
1mg55,00€5mg92,00€10mg152,00€25mg268,00€50mg395,00€100mg583,00€200mg832,00€1mL*10mM (DMSO)105,00€PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.
Formula:C15H11NSPurezza:98.00%Colore e forma:SolidPeso molecolare:237.32Terrestrosin D
CAS:Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.
Formula:C50H80O23Purezza:99.92% - 99.96%Colore e forma:SolidPeso molecolare:1049.16Ganetespib
CAS:Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formula:C20H20N4O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:364.4Ref: TM-T2309
5mg63,00€10mg93,00€25mg126,00€50mg158,00€100mg236,00€200mg401,00€500mg665,00€1mL*10mM (DMSO)71,00€Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Formula:C19H26ClN7OPurezza:99.73%Colore e forma:SolidPeso molecolare:403.91Ref: TM-T22260
2mg39,00€5mg60,00€10mg92,00€25mg173,00€50mg269,00€100mg389,00€200mg555,00€1mL*10mM (DMSO)62,00€Apomine
CAS:Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。Formula:C28H52O7P2Purezza:>99.99%Colore e forma:SolidPeso molecolare:562.66TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Ginsenoside Rh2
CAS:Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.Formula:C36H62O8Purezza:99.20% - 99.76%Colore e forma:White PowderPeso molecolare:622.87Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formula:C42H72O13Purezza:99.04% - 99.3%Colore e forma:SolidPeso molecolare:785.01Ref: TM-T3916
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€1mL*10mM (DMSO)92,00€HA14-1
CAS:HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).Formula:C17H17BrN2O5Purezza:95.07% - 98%Colore e forma:SolidPeso molecolare:409.23LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:500.63Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formula:C23H20N6OPurezza:99% - 99.21%Colore e forma:SolidPeso molecolare:396.44AG1024
CAS:AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Formula:C14H13BrN2OPurezza:98% - 99.37%Colore e forma:SolidPeso molecolare:305.17Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Formula:C20H15Cl3N2OSPurezza:99.483%Colore e forma:SolidPeso molecolare:437.77Ref: TM-T50005
5mg55,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)79,00€Rigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formula:C21H25NO8SPurezza:99.53%Colore e forma:SolidPeso molecolare:451.49PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purezza:97.79% - 99.3%Colore e forma:SolidPeso molecolare:348.36ML311
CAS:ML311 is a selective inhibitor of the Mcl-1/Bim interaction.Formula:C23H24F3N3OPurezza:99.75%Colore e forma:SolidPeso molecolare:415.45Asiaticoside
CAS:Asiaticoside, in Centella asiatica, may treat wounds/burns.Formula:C48H78O19Purezza:98% - 99.96%Colore e forma:PowderPeso molecolare:959.12SC66
CAS:SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).
Formula:C18H16N2OPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:276.33Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formula:C20H20Cl2N6OPurezza:97.33% - 98.92%Colore e forma:SolidPeso molecolare:431.318Ref: TM-T16745
1mg159,00€2mg40,00€5mg58,00€10mg97,00€25mg216,00€50mg406,00€100mg735,00€1mL*10mM (DMSO)64,00€NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.
Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12Idasanutlin
CAS:Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).Formula:C31H29Cl2F2N3O4Purezza:99.13% - 99.88%Colore e forma:SolidPeso molecolare:616.48Ref: TM-T6254
2mg38,00€5mg57,00€10mg90,00€25mg150,00€50mg215,00€100mg356,00€500mg837,00€1mL*10mM (DMSO)79,00€CPTH2
CAS:CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.Formula:C14H14ClN3SPurezza:99.81%Colore e forma:SolidPeso molecolare:291.8ZMC1
CAS:NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Formula:C11H14N4SPurezza:98.97% - 99.76%Colore e forma:SolidPeso molecolare:234.32RAD51 Inhibitor B02
CAS:RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.Formula:C22H17N3OPurezza:99.72% - 99.89%Colore e forma:SolidPeso molecolare:339.39Bendamustine
CAS:Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic LeukemiaFormula:C16H21Cl2N3O2Purezza:99.99% - ≥98%Colore e forma:SolidPeso molecolare:358.26Ref: TM-T8380
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg245,00€50mg385,00€100mg575,00€500mg1.234,00€1mL*10mM (DMSO)89,00€Sertaconazole nitrate
CAS:Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Formula:C20H15Cl3N2OS·HNO3Purezza:98.66% - 99.65%Colore e forma:SolidPeso molecolare:500.78Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purezza:97.75% - 98.02%Colore e forma:SolidPeso molecolare:512.56Grape Seed Extract
CAS:Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.Formula:C32H30O11Purezza:98%Colore e forma:SolidPeso molecolare:590.581CVT-11127
CAS:CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.Formula:C25H23Cl2N5O3Purezza:98.32%Colore e forma:SolidPeso molecolare:512.39N-Ethylmaleimide
CAS:N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.Formula:C6H7NO2Purezza:99.50%Colore e forma:White SolidPeso molecolare:125.13Cucurbitacin IIA
CAS:1.Formula:C32H50O8Purezza:98.62% - 99.87%Colore e forma:SolidPeso molecolare:562.73OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:443.44Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Formula:C31H43N3O8Purezza:98.24% - 99.83%Colore e forma:Dark Purple SolidPeso molecolare:585.692-tert-Butyl-1,4-benzoquinone
CAS:TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.Formula:C10H12O2Purezza:97.19%Colore e forma:SolidPeso molecolare:164.2Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formula:C29H32N6O4SPurezza:98% - 99.42%Colore e forma:SolidPeso molecolare:560.67Ref: TM-T2066
5mg58,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€1mL*10mM (DMSO)71,00€Caudatin
CAS:Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formula:C28H42O7Purezza:98.83% - 99.84%Colore e forma:SolidPeso molecolare:490.63Ref: TM-T3150
1mg52,00€5mg100,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)119,00€Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurezza:98.23% - 99.56%Colore e forma:White To Off-White PowderPeso molecolare:521.68GSK-J4
CAS:GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Formula:C24H27N5O2Purezza:98.24% - 99.98%Colore e forma:SolidPeso molecolare:417.5Ref: TM-T3100
2mg52,00€5mg86,00€10mg122,00€25mg215,00€50mg345,00€100mg523,00€200mg663,00€1mL*10mM (DMSO)134,00€Angelicin
CAS:Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Formula:C11H6O3Purezza:99.86% - 99.89%Colore e forma:White SolidPeso molecolare:186.16Fimasartan
CAS:Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.Formula:C27H31N7OSPurezza:98.96%Colore e forma:SolidPeso molecolare:501.65Lenalidomide hemihydrate
CAS:Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.Formula:C13H13N3O3H2OPurezza:96.22%Colore e forma:SolidPeso molecolare:268.28ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purezza:98.33% - 99.85%Colore e forma:SolidPeso molecolare:539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€1mL*10mM (DMSO)163,00€Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formula:C24H22O6Purezza:98.40% - 98.59%Colore e forma:SolidPeso molecolare:406.43BI-6C9
CAS:BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.Formula:C23H25N3O4S2Purezza:98.39%Colore e forma:SolidPeso molecolare:471.59Ref: TM-T5827
1mg66,00€2mg95,00€5mg144,00€10mg210,00€25mg376,00€50mg557,00€100mg782,00€200mg1.035,00€1mL*10mM (DMSO)150,00€Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purezza:99.63%Colore e forma:SolidPeso molecolare:339.39Ref: TM-T6192
2mg34,00€5mg49,00€10mg60,00€25mg81,00€50mg92,00€100mg129,00€200mg178,00€1mL*10mM (DMSO)50,00€Takinib
CAS:Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).Formula:C18H18N4O2Purezza:98.29% - 99.35%Colore e forma:SolidPeso molecolare:322.36ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Ref: TM-T8375
1mg35,00€2mg52,00€5mg87,00€10mg140,00€25mg246,00€50mg414,00€100mg557,00€1mL*10mM (DMSO)90,00€UMI-77
CAS:UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.Formula:C18H14BrNO5S2Purezza:96% - 99.57%Colore e forma:SolidPeso molecolare:468.34Ref: TM-T6034
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€200mg692,00€500mg1.035,00€1mL*10mM (DMSO)86,00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFormula:C49H58FN9O7SPurezza:97.54% - 98.15%Colore e forma:SolidPeso molecolare:936.1[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formula:C19H28O3Purezza:97.01%Colore e forma:SolidPeso molecolare:304.42Ref: TM-T5430
1mg90,00€5mg197,00€10mg339,00€25mg560,00€50mg793,00€100mg1.063,00€1mL*10mM (DMSO)219,00€R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurezza:98.64% - 99.8%Colore e forma:SolidPeso molecolare:380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€1mL*10mM (DMSO)71,00€(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formula:C20H22O7Purezza:99.88%Colore e forma:SolidPeso molecolare:374.38Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formula:C8H18N3O8PPurezza:99.44%Colore e forma:SolidPeso molecolare:315.22Erdafitinib
CAS:Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formula:C25H30N6O2Purezza:97.00% - 99.36%Colore e forma:SolidPeso molecolare:446.54ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purezza:99.92%Colore e forma:SolidPeso molecolare:405.41Ref: TM-T9697
1mg90,00€5mg215,00€10mg321,00€25mg582,00€50mg873,00€100mg1.216,00€1mL*10mM (DMSO)236,00€Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurezza:99.53% - 99.86%Colore e forma:SolidPeso molecolare:499.7MGH-CP1
CAS:MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.Formula:C20H24N4OSPurezza:98.66%Colore e forma:SolidPeso molecolare:368.5Ref: TM-T9032
2mg38,00€5mg57,00€10mg93,00€25mg177,00€50mg313,00€100mg507,00€200mg710,00€1mL*10mM (DMSO)67,00€BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurezza:99.46%Colore e forma:SolidPeso molecolare:463.32Ref: TM-T6776
1mg35,00€5mg79,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€1mL*10mM (DMSO)93,00€Lycorine
CAS:Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.Formula:C16H17NO4Purezza:98.60% - 99.95%Colore e forma:SolidPeso molecolare:287.312BAct
CAS:2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress responseFormula:C19H16ClF3N4O3Purezza:97.97% - 99.04%Colore e forma:SolidPeso molecolare:440.8Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purezza:99.50% - 99.85%Colore e forma:SolidPeso molecolare:360.31ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurezza:99.36% - 99.56%Colore e forma:SolidPeso molecolare:407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€1mL*10mM (DMSO)71,00€SW106065
CAS:SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.Formula:C10H8N2OSPurezza:99.97%Colore e forma:SolidPeso molecolare:204.25(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purezza:99.14%Colore e forma:SolidPeso molecolare:275.34Nur77 modulator 1
CAS:Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.Formula:C28H25N5O2SPurezza:99.62%Colore e forma:SolidPeso molecolare:495.6Ref: TM-T40130
1mg64,00€5mg140,00€10mg226,00€25mg373,00€50mg509,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)153,00€KRIBB11
CAS:KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.Formula:C13H12N6O2Purezza:97.25% - 99.91%Colore e forma:SolidPeso molecolare:284.27Ref: TM-T3652
5mg49,00€10mg73,00€25mg150,00€50mg249,00€100mg484,00€200mg680,00€500mg1.035,00€1mL*10mM (DMSO)50,00€Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Formula:C47H76O18Purezza:97.15% - 99.79%Colore e forma:SolidPeso molecolare:929.10Ginsenoside Rg6
CAS:Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFormula:C42H70O12Purezza:97.34%Colore e forma:SolidPeso molecolare:767GSK2334470
CAS:GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.Formula:C25H34N8OPurezza:99.57% - 99.87%Colore e forma:SolidPeso molecolare:462.59Dictamine
CAS:Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi.Formula:C12H9NO2Purezza:99.72% - 99.889%Colore e forma:SolidPeso molecolare:199.21Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurezza:97.56% - >99.99%Colore e forma:SolidPeso molecolare:498.64
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