Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(5 prodotti)
- Caspasi(151 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(105 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(58 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6043 prodotti di "Apoptosi"
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BRD3308
CAS:BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.Formula:C15H14FN3O2Purezza:97%Colore e forma:SolidPeso molecolare:287.29Ref: TM-T8233
2mg42,00€5mg62,00€10mg92,00€25mg178,00€50mg295,00€100mg462,00€200mg655,00€1mL*10mM (DMSO)66,00€INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formula:C20H21N3O5SPurezza:99.5%Colore e forma:SolidPeso molecolare:415.46Ref: TM-T5417
1mg42,00€5mg90,00€10mg140,00€25mg245,00€50mg368,00€100mg500,00€200mg688,00€1mL*10mM (DMSO)90,00€Methotrexate disodium
CAS:Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFormula:C20H20N8Na2O5Purezza:99.77% - 99.96%Colore e forma:SolidPeso molecolare:498.4Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Formula:C34H50O12Purezza:99.07% - 99.3%Colore e forma:Colourless FilmPeso molecolare:650.75(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purezza:99.14%Colore e forma:SolidPeso molecolare:275.34PS-1145
CAS:PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.Formula:C17H11ClN4OPurezza:98.81% - >99.99%Colore e forma:SolidPeso molecolare:322.75Ref: TM-T3094
1mg39,00€2mg52,00€5mg87,00€10mg120,00€25mg245,00€50mg394,00€100mg620,00€200mg875,00€1mL*10mM (DMSO)96,00€SW106065
CAS:SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.Formula:C10H8N2OSPurezza:99.97%Colore e forma:SolidPeso molecolare:204.25RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurezza:99.56%Colore e forma:SolidPeso molecolare:518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurezza:99.36% - 99.56%Colore e forma:SolidPeso molecolare:407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€1mL*10mM (DMSO)71,00€LASSBio-1135
CAS:LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Formula:C18H14N4Purezza:99.09%Colore e forma:SolidPeso molecolare:286.33Epoxomicin
CAS:Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.Formula:C28H50N4O7Purezza:98.65% - 98.86%Colore e forma:White To Off-White SolidPeso molecolare:554.72Ref: TM-T6830
1mg125,00€5mg311,00€10mg502,00€25mg817,00€50mg1.130,00€100mg1.501,00€500mg3.022,00€1mL*10mM (DMSO)375,00€Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purezza:98.75% - 99.57%Colore e forma:SolidPeso molecolare:199.25Ref: TM-T4414
5mg73,00€10mg105,00€25mg207,00€50mg368,00€100mg652,00€500mg1.320,00€1mL*10mM (DMSO)81,00€Helichrysetin
CAS:Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.Formula:C16H14O5Purezza:96.32% - ≥95%Colore e forma:SolidPeso molecolare:286.28Ref: TM-TN1727
1mg90,00€5mg222,00€10mg331,00€25mg537,00€50mgPrezzo su richiesta1mL*10mM (DMSO)200,00€Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg90,00€5mg203,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)224,00€Ligustrazine
CAS:Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.Formula:C8H12N2Purezza:99.91% - >99.99%Colore e forma:White Crystals Or PowderPeso molecolare:136.19Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formula:C31H42N6O4Purezza:99.45% - ≥98%Colore e forma:White SolidPeso molecolare:562.7Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor
Formula:C40H54N4O10SPurezza:99.85%Colore e forma:White To Light Yellow Crystal PowdePeso molecolare:782.9Paederosidic acid
CAS:Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.Formula:C18H24O12SPurezza:98% - 99.56%Colore e forma:SolidPeso molecolare:464.444-Methyldaphnetin
CAS:4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formula:C10H8O4Purezza:99.73%Colore e forma:SolidPeso molecolare:192.17(20S)-Protopanaxatriol
CAS:(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoidFormula:C30H52O4Purezza:95% - 99%Colore e forma:SolidPeso molecolare:476.73Ref: TM-T2810
2mg34,00€5mg50,00€10mg66,00€25mg114,00€50mg178,00€100mg295,00€200mg442,00€1mL*10mM (DMSO)55,00€OsMundacetone
CAS:OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.Formula:C10H10O3Purezza:99.59% - ≥95%Colore e forma:SolidPeso molecolare:178.18K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purezza:97.16%Colore e forma:SolidPeso molecolare:449.67NVP-TAE 226
CAS:NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formula:C23H25ClN6O3Purezza:98.07% - 98.78%Colore e forma:SolidPeso molecolare:468.94Ref: TM-T1918
1mg46,00€2mg59,00€5mg96,00€10mg155,00€25mg250,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)96,00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purezza:98.92% - 99.52%Colore e forma:SolidPeso molecolare:310.35Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purezza:99.6% - 99.84%Colore e forma:SolidPeso molecolare:719.91Sclareol
CAS:Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.Formula:C20H36O2Purezza:99.58% - 99.97%Colore e forma:White Fine PowderPeso molecolare:308.5Hispidol
CAS:Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormula:C15H10O4Purezza:97.86% - 98.45%Colore e forma:SolidPeso molecolare:254.24Ref: TM-T4319
1mg42,00€2mg56,00€5mg93,00€10mg137,00€25mg200,00€50mg260,00€100mg409,00€200mg560,00€500mg954,00€1mL*10mM (DMSO)92,00€PUMA BH3 Free base
PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd ofFormula:C130H206N42O45SPurezza:96.64%Colore e forma:SolidPeso molecolare:3109.35Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurezza:99.65% - 99.79%Colore e forma:SolidPeso molecolare:404.44Ref: TM-T6255
1mg44,00€2mg57,00€5mg93,00€10mg133,00€25mg260,00€50mg416,00€100mg665,00€200mg888,00€1mL*10mM (DMSO)92,00€Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formula:C8H16O2Purezza:97.78% - 99%Colore e forma:Colourless To Pale Yellow Liquid ViscousPeso molecolare:144.21Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formula:C18H26ClN3O3·C4H6O4Purezza:99.24%Colore e forma:SolidPeso molecolare:485.96PNU-74654
CAS:PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).Formula:C19H16N2O3Purezza:97.27%Colore e forma:SolidPeso molecolare:320.34Ref: TM-T7204
2mg40,00€5mg56,00€10mg79,00€25mg150,00€50mg259,00€100mg432,00€200mg700,00€1mL*10mM (DMSO)64,00€Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purezza:99.50% - 99.85%Colore e forma:SolidPeso molecolare:360.31Luminespib
CAS:Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.
Formula:C26H31N3O5Purezza:98% - 99.25%Colore e forma:SolidPeso molecolare:465.54DD1
CAS:DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.Formula:C16H14N2O3Purezza:99.57%Colore e forma:SolidPeso molecolare:282.29Ref: TM-T8978
1mg74,00€5mg138,00€10mg226,00€25mg356,00€50mg492,00€100mg665,00€200mg898,00€1mL*10mM (DMSO)145,00€NSC59984
CAS:NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.Formula:C12H15N3O4Purezza:99.33% - 99.59%Colore e forma:SolidPeso molecolare:265.27Ref: TM-T6910
5mg66,00€10mg102,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€1mL*10mM (DMSO)73,00€20(R)-Ginsenoside Rh2
CAS:20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.Formula:C36H62O8Purezza:99.58%Colore e forma:SolidPeso molecolare:622.87Ref: TM-T3813
1mg46,00€5mg87,00€10mg123,00€25mg192,00€50mg264,00€100mg378,00€200mg552,00€1mL*10mM (DMSO)119,00€Millepachine
CAS:Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.Formula:C22H22O4Purezza:99.73%Colore e forma:SolidPeso molecolare:350.41Ref: TM-T38815
1mg55,00€5mg116,00€10mg156,00€25mg259,00€50mg378,00€100mg567,00€200mg748,00€1mL*10mM (DMSO)134,00€2BAct
CAS:2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress responseFormula:C19H16ClF3N4O3Purezza:97.97% - 99.04%Colore e forma:SolidPeso molecolare:440.8Vanillyl Alcohol
CAS:Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.Formula:C8H10O3Purezza:97.02% - 98.42%Colore e forma:Crystalline White To Off-White PowderPeso molecolare:154.16Tubeimoside I
CAS:Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).Formula:C63H98O29Purezza:98.89% - 99.94%Colore e forma:SolidPeso molecolare:1319.43Ref: TM-T2715
5mg34,00€10mg42,00€25mg58,00€50mg81,00€100mg105,00€200mg152,00€500mg245,00€1mL*10mM (DMSO)52,00€Lycorine
CAS:Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.Formula:C16H17NO4Purezza:98.60% - 99.95%Colore e forma:SolidPeso molecolare:287.31NVP 231
CAS:NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.
Formula:C25H25N3O2SPurezza:99.16% - ≥95%Colore e forma:SolidPeso molecolare:431.55BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurezza:99.46%Colore e forma:SolidPeso molecolare:463.32Ref: TM-T6776
1mg35,00€5mg79,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€1mL*10mM (DMSO)93,00€Abacavir sulfate
CAS:Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormula:C14H18N6OH2O4SPurezza:99.79% - 99.85%Colore e forma:White To Off-White SolidPeso molecolare:335.38MGH-CP1
CAS:MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.Formula:C20H24N4OSPurezza:98.66%Colore e forma:SolidPeso molecolare:368.5Ref: TM-T9032
2mg38,00€5mg57,00€10mg93,00€25mg177,00€50mg313,00€100mg507,00€200mg710,00€1mL*10mM (DMSO)67,00€Rimiducid
CAS:Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.Formula:C78H98N4O20Purezza:99.54%Colore e forma:SolidPeso molecolare:1411.63Ref: TM-T14298
1mg129,00€2mg177,00€5mg285,00€10mg420,00€25mg692,00€50mg973,00€100mg1.305,00€500mg2.602,00€Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurezza:99.53% - 99.86%Colore e forma:SolidPeso molecolare:499.7ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purezza:99.92%Colore e forma:SolidPeso molecolare:405.41Ref: TM-T9697
1mg90,00€5mg215,00€10mg321,00€25mg582,00€50mg873,00€100mg1.216,00€1mL*10mM (DMSO)236,00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purezza:99.25%Colore e forma:Yellowish SolidPeso molecolare:379.88Ref: TM-T6568
5mg44,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€1mL*10mM (DMSO)48,00€Erdafitinib
CAS:Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formula:C25H30N6O2Purezza:97.00% - 99.36%Colore e forma:SolidPeso molecolare:446.54NSC 15364
CAS:NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.Formula:C13H14N4OPurezza:98.67%Colore e forma:SolidPeso molecolare:242.28Trabectedin
CAS:Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.Formula:C39H43N3O11SPurezza:≥98%Colore e forma:SolidPeso molecolare:761.84Mirodenafil dihydrochloride
CAS:Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H39Cl2N5O5SPurezza:99.64% - 99.78%Colore e forma:SolidPeso molecolare:604.59Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formula:C8H18N3O8PPurezza:99.44%Colore e forma:SolidPeso molecolare:315.22(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formula:C20H22O7Purezza:99.88%Colore e forma:SolidPeso molecolare:374.38Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purezza:99.24% - 99.82%Colore e forma:Off-White PowderPeso molecolare:466.53Ref: TM-T6680
1mg58,00€2mg82,00€5mg92,00€10mg138,00€25mg234,00€50mg380,00€100mg565,00€500mg1.215,00€1mL*10mM (DMSO)103,00€R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurezza:98.64% - 99.8%Colore e forma:SolidPeso molecolare:380.77Ref: TM-T4637
1mg35,00€2mg46,00€5mg66,00€10mg96,00€25mg207,00€50mg283,00€100mg464,00€200mg658,00€1mL*10mM (DMSO)74,00€[8]-Shogaol
CAS:[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formula:C19H28O3Purezza:97.01%Colore e forma:SolidPeso molecolare:304.42Ref: TM-T5430
1mg90,00€5mg197,00€10mg339,00€25mg560,00€50mg793,00€100mg1.063,00€1mL*10mM (DMSO)219,00€ACBI1
CAS:ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFormula:C49H58FN9O7SPurezza:97.54% - 98.15%Colore e forma:SolidPeso molecolare:936.1UMI-77
CAS:UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.Formula:C18H14BrNO5S2Purezza:96% - 99.57%Colore e forma:SolidPeso molecolare:468.34Ref: TM-T6034
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€200mg692,00€500mg1.035,00€1mL*10mM (DMSO)86,00€ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Ref: TM-T8375
1mg35,00€2mg52,00€5mg87,00€10mg140,00€25mg246,00€50mg414,00€100mg557,00€1mL*10mM (DMSO)90,00€Takinib
CAS:Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).Formula:C18H18N4O2Purezza:98.29% - 99.35%Colore e forma:SolidPeso molecolare:322.36Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purezza:99.63%Colore e forma:SolidPeso molecolare:339.39Ref: TM-T6192
2mg34,00€5mg49,00€10mg60,00€25mg81,00€50mg92,00€100mg129,00€200mg178,00€1mL*10mM (DMSO)50,00€BI-6C9
CAS:BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.Formula:C23H25N3O4S2Purezza:98.39%Colore e forma:SolidPeso molecolare:471.59Ref: TM-T5827
1mg66,00€2mg95,00€5mg144,00€10mg210,00€25mg376,00€50mg557,00€100mg782,00€200mg1.035,00€1mL*10mM (DMSO)150,00€Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formula:C24H22O6Purezza:98.40% - 98.59%Colore e forma:SolidPeso molecolare:406.43Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formula:C22H22O7Purezza:99.65% - 99.84%Colore e forma:SolidPeso molecolare:398.41ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purezza:98.33% - 99.85%Colore e forma:SolidPeso molecolare:539.68Ref: TM-TQ0029
1mg84,00€5mg144,00€10mg216,00€25mg432,00€50mg638,00€100mg908,00€1mL*10mM (DMSO)172,00€Lenalidomide hemihydrate
CAS:Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.Formula:C13H13N3O3H2OPurezza:96.22%Colore e forma:SolidPeso molecolare:268.28Fimasartan
CAS:Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.Formula:C27H31N7OSPurezza:98.96%Colore e forma:SolidPeso molecolare:501.653-O-Methylgallic acid
CAS:3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins andFormula:C8H8O5Purezza:99.56%Colore e forma:SolidPeso molecolare:184.15W-7 hydrochloride
CAS:W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochlorideFormula:C16H22Cl2N2O2SPurezza:99.63%Colore e forma:White Crystalline SolidPeso molecolare:377.32ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purezza:98% - 99.75%Colore e forma:SolidPeso molecolare:566.51Clobenpropit dihydrobromide
CAS:Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)Formula:C14H19Br2ClN4SPurezza:99.86%Colore e forma:SolidPeso molecolare:470.7SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。Formula:C19H13Cl2N3O2SPurezza:98.9%Colore e forma:SolidPeso molecolare:418.3Degrasyn
CAS:Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.Formula:C19H18BrN3OPurezza:98.32% - 99.98%Colore e forma:SolidPeso molecolare:384.27Ref: TM-T6300
2mg42,00€5mg60,00€10mg92,00€25mg188,00€50mg324,00€100mg505,00€200mg710,00€1mL*10mM (DMSO)66,00€Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Formula:C21H19NO3SPurezza:98.76% - 99.13%Colore e forma:SolidPeso molecolare:365.45Ref: TM-T1867
2mg38,00€5mg57,00€10mg93,00€25mg166,00€50mg260,00€100mg416,00€500mg888,00€1mL*10mM (DMSO)63,00€iCRT3
CAS:iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.Formula:C23H26N2O2SPurezza:98.32% - 98.47%Colore e forma:SolidPeso molecolare:394.53Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:653.21Angelicin
CAS:Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Formula:C11H6O3Purezza:99.86% - 99.89%Colore e forma:White SolidPeso molecolare:186.16EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurezza:98.3% - 99.76%Colore e forma:SolidPeso molecolare:413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formula:C26H23FN8OPurezza:99.31%Colore e forma:SolidPeso molecolare:482.51Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purezza:98.92%Colore e forma:SolidPeso molecolare:338.353-Nitropropanoic acid
CAS:3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.Formula:C3H5NO4Purezza:98.35% - 99.94%Colore e forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecolare:119.08GSK-J4
CAS:GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Formula:C24H27N5O2Purezza:98.24% - 99.98%Colore e forma:SolidPeso molecolare:417.5Ref: TM-T3100
2mg52,00€5mg86,00€10mg122,00€25mg215,00€50mg345,00€100mg523,00€200mg663,00€1mL*10mM (DMSO)134,00€TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formula:C21H17ClN2O6Purezza:97.62% - 99.09%Colore e forma:SolidPeso molecolare:428.82Nelarabine
CAS:Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formula:C11H15N5O5Purezza:98.10% - 99.6%Colore e forma:White SolidPeso molecolare:297.27Ref: TM-T6603
1mg40,00€2mg54,00€5mg84,00€10mg133,00€25mg234,00€50mg414,00€100mg520,00€500mg1.099,00€1mL*10mM (DMSO)84,00€Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formula:C20H22O6Purezza:99.11% - 99.64%Colore e forma:White Crystalline PowderPeso molecolare:358.39Ref: TM-T5S1058
1mg52,00€2mg74,00€5mg108,00€10mg158,00€25mg268,00€50mg409,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)133,00€Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurezza:98.23% - 99.56%Colore e forma:White To Off-White PowderPeso molecolare:521.68Demethylzeylasteral
CAS:Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.Formula:C29H36O6Purezza:98.74% - 99.54%Colore e forma:SolidPeso molecolare:480.59Angiotensin II human
CAS:Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.Formula:C50H71N13O12Purezza:95% - >99.99%Colore e forma:SolidPeso molecolare:1046.18Caudatin
CAS:Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formula:C28H42O7Purezza:98.83% - 99.84%Colore e forma:SolidPeso molecolare:490.63Ref: TM-T3150
1mg52,00€5mg100,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)119,00€Quizartinib
CAS:Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formula:C29H32N6O4SPurezza:98% - 99.42%Colore e forma:SolidPeso molecolare:560.67Ref: TM-T2066
5mg58,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€1mL*10mM (DMSO)71,00€PFI-90
CAS:PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.Formula:C11H10N4OPurezza:99.46%Colore e forma:SolidPeso molecolare:214.22Mancozeb
CAS:Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.Formula:C8H12MnN4S8ZnPurezza:98%Colore e forma:Grayish-Yellow PowderPeso molecolare:541.08CCF642
CAS:CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.Formula:C15H10N2O4S3Purezza:97.12% - 98.82%Colore e forma:SolidPeso molecolare:378.45Ref: TM-T6800
1mg34,00€2mg46,00€5mg63,00€10mg93,00€25mg170,00€50mg281,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)66,00€GSK4112
CAS:GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formula:C18H21ClN2O4SPurezza:99.69%Colore e forma:SolidPeso molecolare:396.89Triglycidyl isocyanurate
CAS:Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.Formula:C12H15N3O6Purezza:99.01%Colore e forma:White Solid ParticulatesPeso molecolare:297.26EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurezza:99.71%Colore e forma:SolidPeso molecolare:311.33Ref: TM-T27242
1g1.510,00€1mg40,00€5mg85,00€10mg133,00€25mg235,00€50mg354,00€100mg533,00€500mg1.130,00€1mL*10mM (DMSO)93,00€Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurezza:98.71%Colore e forma:SolidPeso molecolare:253.27Ref: TM-T19692
1mg99,00€5mg222,00€10mg344,00€25mg550,00€50mg773,00€100mg1.063,00€1mL*10mM (DMSO)205,00€
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