Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(142 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5903 prodotti di "Apoptosi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
4-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurezza:97.18%Colore e forma:SolidPeso molecolare:313.42Perillyl alcohol
CAS:<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Formula:C10H16OPurezza:97.36%Colore e forma:SolidPeso molecolare:152.23NAE-IN-M22
CAS:<p>NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.</p>Formula:C20H24Cl2N2Purezza:97.65%Colore e forma:SolidPeso molecolare:363.32Avadomide HCl
CAS:Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.Formula:C14H15ClN4O3Colore e forma:SolidPeso molecolare:322.75BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purezza:97.13% - 97.54%Colore e forma:SolidPeso molecolare:464.56Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Formula:C44H51ClF3N5O5S3Purezza:99.87%Colore e forma:SolidPeso molecolare:918.55Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formula:C20H20N8Na2O5Purezza:99.77% - 99.96%Colore e forma:SolidPeso molecolare:498.4Nutlin-3
CAS:Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purezza:98.13% - 99.89%Colore e forma:SolidPeso molecolare:581.49PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purezza:99.40%Colore e forma:SolidPeso molecolare:557.56Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurezza:98% - 99.91%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:301.32Thalidomide-PEG4-Propargyl
CAS:Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.Formula:C24H28N2O9Purezza:97.46%Colore e forma:SolidPeso molecolare:488.49Coenzyme Q9
CAS:<p>Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma.</p>Formula:C54H82O4Purezza:98.2% - 99.47%Colore e forma:SolidPeso molecolare:795.23Amifostine thiol dihydrochloride
CAS:Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.Formula:C5H16Cl2N2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:207.165Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Formula:C13H10O5Purezza:99.85% - ≥95%Colore e forma:SolidPeso molecolare:246.22Mitochonic acid 5
CAS:<p>MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.</p>Formula:C18H13F2NO3Purezza:98.85%Colore e forma:SolidPeso molecolare:329.3T-1101 tosylate
CAS:T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.Formula:C31H31N5O6S3Purezza:98.1%Colore e forma:SolidPeso molecolare:665.8Sinapinic Acid
CAS:<p>Sinapinic Acid (Synapoic acid) is a phenolic isolated from the roots of Hydnophytum formicarumJack. It is an HDAC inhibitor and also inhibits ACE-I activity.</p>Formula:C11H12O5Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:224.21Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Deltamethrin
CAS:<p>Deltamethrin, a pyrethroid insecticide, causes reversible hind limb rigidity in rats and is used for crop protection and disease control.</p>Formula:C22H19Br2NO3Purezza:99.25% - 99.85%Colore e forma:White To Off-White Crystals Or PowderPeso molecolare:505.20NSC 73150
CAS:<p>6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.</p>Formula:C12H12N4O2Purezza:99.84%Colore e forma:SolidPeso molecolare:244.25OTS964 hydrochloride
CAS:<p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>Formula:C23H24N2O2S·HClPurezza:96.5% - 98.03%Colore e forma:SolidPeso molecolare:428.97Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Formula:C21H28FN3O7Purezza:98.24% - 99.79%Colore e forma:SolidPeso molecolare:453.464-Methyldaphnetin
CAS:4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formula:C10H8O4Purezza:99.73%Colore e forma:SolidPeso molecolare:192.17Fimasartan
CAS:<p>Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.</p>Formula:C27H31N7OSPurezza:98.96%Colore e forma:SolidPeso molecolare:501.65Rhapontin
CAS:Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.Formula:C21H24O9Purezza:99% - 99.91%Colore e forma:Light YellowPeso molecolare:420.41M50054
CAS:Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.Formula:C13H16O4Purezza:97.8%Colore e forma:SolidPeso molecolare:236.26Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36Sodium taurodeoxycholate hydrate
CAS:<p>Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations of</p>Formula:C26H44NO6S·Na·H2OPurezza:99.78%Colore e forma:SolidPeso molecolare:539.7Evofosfamide
CAS:<p>Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage and potentially induce apoptosis.</p>Formula:C9H16Br2N5O4PPurezza:98.74% - 99.75%Colore e forma:SolidPeso molecolare:449.04(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Formula:C18H15N5O6S2Purezza:97.62% - 98%Colore e forma:SolidPeso molecolare:461.47Angelicin
CAS:Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Formula:C11H6O3Purezza:99.86% - 99.89%Colore e forma:White SolidPeso molecolare:186.16Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formula:C18H20N3NaO3SPurezza:98% - 99.912%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:381.42Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purezza:98% - 99.8%Colore e forma:SolidPeso molecolare:588.66Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Formula:C39H62O12Purezza:99.60% - 99.75%Colore e forma:SolidPeso molecolare:722.9Acenocoumarol
CAS:<p>Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.</p>Formula:C19H15NO6Purezza:99.95%Colore e forma:Crystals SolidPeso molecolare:353.33TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurezza:99.71%Colore e forma:SolidPeso molecolare:396.44DEL-22379
CAS:DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.Formula:C26H28N4O3Purezza:99.3% - 99.53%Colore e forma:SolidPeso molecolare:444.53Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurezza:99.13% - 99.97%Colore e forma:SolidPeso molecolare:530.5Piperacetazine
CAS:Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.Formula:C24H30N2O2SPurezza:99.9% - 99.92%Colore e forma:SolidPeso molecolare:410.57Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formula:C15H10O4Purezza:97.86% - 98.45%Colore e forma:SolidPeso molecolare:254.24Laquinimod sodium
CAS:Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.Formula:C19H16ClN2NaO3Colore e forma:SolidPeso molecolare:378.79Crebanine
CAS:Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.Formula:C20H21NO4Purezza:99.17% - 99.77%Colore e forma:SolidPeso molecolare:339.39Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formula:C22H30N6OSBrHPurezza:97.83% - 99.92%Colore e forma:SolidPeso molecolare:628.86Pomolic acid
CAS:Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-Formula:C30H48O4Purezza:96.84% - 99.79%Colore e forma:SolidPeso molecolare:472.7GSK-J4
CAS:GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Formula:C24H27N5O2Purezza:98.24% - 99.98%Colore e forma:SolidPeso molecolare:417.5Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurezza:99.65% - 99.79%Colore e forma:SolidPeso molecolare:404.44Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purezza:99.8% - ≥95%Colore e forma:White CrystalPeso molecolare:307.43Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formula:C18H26ClN3O3·C4H6O4Purezza:99.24%Colore e forma:SolidPeso molecolare:485.96Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Formula:C10H13Cl2NPurezza:99.54%Colore e forma:SolidPeso molecolare:218.12
