Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(144 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(139 prodotti)
- PDK(9 prodotti)
- PERK(27 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(62 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6063 prodotti di "Apoptosi"
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AZD0424
CAS:AZD0424: oral Src/Abl kinase inhibitor; potential anticancer; induces apoptosis, cell cycle arrest in lymphoma.Formula:C25H29ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:528.99PARP10/15-IN-2
CAS:PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.Formula:C15H11FN2O3Colore e forma:SolidPeso molecolare:286.26CDK4/6-IN-10
CDK4/6-IN-10: Oral CDK4 (IC50: 22 nM) & CDK6 (IC50: 10 nM) inhibitor with anti-cancer potential for MM research.Colore e forma:SolidRET-IN-11
RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.Formula:C27H30FN9OColore e forma:SolidPeso molecolare:515.59CCT369260
CAS:CCT369260 (compound 1), an orally active inhibitor targeting B-cell lymphoma 6 (BCL6), demonstrates anti-tumor efficacy with an IC50 value of 520 nM [1].Formula:C24H31ClF2N6O2Colore e forma:SolidPeso molecolare:508.99BCL6-IN-9
CAS:BCL6-IN-9 (compound 1) is a potent inhibitor of B-cell lymphoma 6 protein (BCL6) (IC50: 3.9 nM) and can be used to study cancer.Formula:C22H18ClF2N5O2Colore e forma:SolidPeso molecolare:457.86Anticancer agent 65
CAS:Anticancer agent 65: Effective on A549 cells, IC50 1.07 μM, halts S phase, triggers apoptosis, elevates p53/p21, causes ROS and MMP collapse.Formula:C36H63NO5Colore e forma:SolidPeso molecolare:589.89GL0388
GL0388, a Bax activator, induces apoptosis, hinders breast cancer growth, and has IC50 of 0.299-1.57 μM.Formula:C21H17FN2OColore e forma:SolidPeso molecolare:332.37mTOR/HDAC6-IN-1
mTOR/HDAC6-IN-1 inhibits HDAC6 (IC50: 56 nM) & mTOR (IC50: 133.7 nM), may treat TNBC by inducing autophagy and apoptosis.Formula:C20H20ClN5O2Colore e forma:SolidPeso molecolare:397.86Ganoderic acid R
CAS:Ganoderic acid R: potent anticancer, induces apoptosis, cytotoxic to MDR and sensitive tumor cells.Formula:C34H50O6Colore e forma:SolidPeso molecolare:554.76RWJ-56110
CAS:protease-activated receptor-1 (PAR1) antagonistFormula:C41H43Cl2F2N7O3Purezza:98%Colore e forma:SolidPeso molecolare:790.73Flizasertib
CAS:Flizasertib is a serine/threonine kinase inhibitor that acts by inhibiting RIPK1, which has anti-inflammatory and therapeutic effects on immune disorders.Formula:C15H14FN3OPurezza:99.39% - 99.57%Colore e forma:SolidPeso molecolare:271.29BRD1991
CAS:BRD1991 is a chemical compound that specifically disrupts the interaction between Beclin 1 and Bcl-2, thereby inducing autophagy.Formula:C33H35Cl2N3O4Colore e forma:SolidPeso molecolare:608.55HDAC6/HSP90-IN-2
HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.Formula:C19H22N2O5Colore e forma:SolidPeso molecolare:358.39Anticancer agent 53
CAS:Anticancer agent 53 exhibits potent in vitro cytotoxicity, triggers apoptosis, halts S/G2/M cycle, and has antitumor effects without toxicity.Formula:C31H25FN4O6SColore e forma:SolidPeso molecolare:600.62D-Cl-amidine hydrochloride
D-Cl-amidine hydrochloride is a potent and highly selective inhibitor of PAD1. It exhibits excellent tolerance and does not induce significant toxicity [1].Formula:C14H20Cl2N4O2Colore e forma:SolidPeso molecolare:347.24ZLHQ-5f
ZLHQ-5f inhibits CDK2/Topo I, with IC50 of 0.145μM for CDK2/CycA2, and promotes apoptosis by arresting HCT116 cells in S phase.Formula:C28H25N5O2Colore e forma:SolidPeso molecolare:463.53HDAC-IN-9
HDAC-IN-9, a dual tubulin/HDAC inhibitor, impedes A549 cell invasion/migration and shows strong anti-tumor/angiogenic effects.Formula:C33H38N2O4Colore e forma:SolidPeso molecolare:526.67hCAIX/XII-IN-5
Coumarin 9a: Selective inhibitor of hCA IX/XII (Ki 93.3/85.7 nM), blocks cancer cell growth, and induces apoptosis.Formula:C18H13NO3Colore e forma:SolidPeso molecolare:291.3RIPK1-IN-14
CAS:RIPK1-IN-14 inhibits RIPK1 with 92 nM IC50 and reduces necrotic apoptosis in U937 cells.Colore e forma:Soild
