Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(3 prodotti)
- Caspasi(153 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(92 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(49 prodotti)
- c-RET(60 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6031 prodotti di "Apoptosi"
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[1,1'-Biphenyl]-3-amine
CAS:[1,1'-Biphenyl]-3-amine is an inhibitor of MAO-A and MAO-B and can inhibit the cell viability of HT-29, HEK 293, and MCF-7 cells.Formula:C12H11NPurezza:99.78%Colore e forma:SolidPeso molecolare:169.22Mcl1-IN-12
CAS:Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.Formula:C45H46N4O6S2Purezza:98%Colore e forma:SolidPeso molecolare:803Polyinosinic-polycytidylic acid potassium
CAS:Poly(I:C) potassium is a synthetic RNA analog, activates TLR3/RIG-I, used as a vaccine adjuvant, and induces apoptosis in cancer cells.Formula:(C10H13N4O8P)x·(C9H14N3O8P)x·xKColore e forma:SolidPTD-p65-P1 Peptide TFA
Ptd-p65-p1 Peptide TFA inhibits NF-kappaB, has a cell-penetrating antennapedia sequence, and selectively blocks NF-kappaB activation.
Formula:C170H276F3N57O46SPurezza:98%Colore e forma:SolidPeso molecolare:3943.52PERK-IN-4
CAS:PERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM.PERK-IN-4 can be used in the study of cancer and neurological disorders.Formula:C24H19F4N5OPurezza:99.44% - 99.49%Colore e forma:SolidPeso molecolare:469.43Tubulysin B
CAS:Tubulysin B: a potent, cytotoxic microtubule-disrupting peptide from Archangium geophyra and Angiococcus disciformis.Formula:C42H63N5O10SPurezza:98%Colore e forma:SolidPeso molecolare:830.04Reveromycin A
CAS:Reveromycin A from Streptomyces sp. inhibits epidermal growth, tumors, and C. albicans; affects osteoclasts. IC50: 0.7-1.9 μg/ml; MIC: 2 μg/ml.Formula:C36H52O11Colore e forma:SolidPeso molecolare:660.79Tubulin inhibitor 34
Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis.Formula:C21H22N4O3SColore e forma:SolidPeso molecolare:410.492-aminobenzo[d]thiazol-6-ol
CAS:2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.Formula:C7H6N2OSPurezza:98.92%Colore e forma:SolidPeso molecolare:166.2MRT-2359
CAS:"MRT-2359: Oral GSPT1 reducer, anti-cancer, targets NSCLC/SCLC, effective on MYC-driven cells."
Formula:C22H17F4N3O6Purezza:98.69%Colore e forma:SoildPeso molecolare:495.38PZ703b hydrochloride
PZ703b hydrochloride, a Bcl-xl PROTAC, triggers apoptosis and halts cancer growth; used in bladder cancer studies.Formula:C80H103Cl2F3N10O11S4Colore e forma:SolidPeso molecolare:1636.9Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-amido-C8-NH2 hydrochloride, a synthetic cereblon ligand-linker for PROTAC synthesis.Formula:C23H31ClN4O6Purezza:98%Colore e forma:SolidPeso molecolare:494.97PI3Kα-IN-14
PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and markedly diminishes mitochondrial membrane potential, resulting inPurezza:98%Colore e forma:Odour SolidShepherdin (79-87)
CAS:Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.Formula:C41H64N12O12SPurezza:98%Colore e forma:SolidPeso molecolare:949.09Z-VEID-FMK
CAS:Z-VEID-FMK is a selective caspase-6 peptide inhibitor that irreversibly covalently binds to the enzyme, thereby inhibiting apoptosis and DNA breakage.Formula:C31H45FN4O10Purezza:98%Colore e forma:SolidPeso molecolare:652.71p38-α MAPK-IN-8
p38-α MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. It exhibits cytotoxicity toward various tumor cells, inducing cell cycle arrest and apoptosis, as well as increasing reactive oxygen species (ROS) production and causing mitochondrial membrane potential depolarization. Its antitumor activity may be related to the p38α MAPK pathway, making it a potential candidate for cancer research.Formula:C49H62BrO4PColore e forma:SolidPeso molecolare:825.892PUMA BH3
PUMA BH3 activates Bak, binds Bcl-2; triggers apoptosis via cytochrome C release; Kd 26 nM.Formula:C128H202N42O43SPurezza:98%Colore e forma:SolidPeso molecolare:3049.3CYP51/PD-L1-IN-4
CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target inhibitor of CYP51/PD-L1, displaying IC50 values of 0.17 and 0.021 μM, respectively.Formula:C27H28N4O3Colore e forma:SolidPeso molecolare:456.54BRAFV600E/JNK-IN-1
BRAFV600E/JNK-IN-1 (Compound 14c) is an inhibitor of JNK1, JNK2, JNK3, and BRAFV600E, with IC50 values of 0.51 μM, 0.53 μM, 1.02 μM, and 0.009 μM, respectively. It also inhibits the phosphorylation of MEK1/2 and ERK1/2. Additionally, BRAFV600E/JNK-IN-1 suppresses tumor cell proliferation, NO release, and PGE2 production, exhibiting both antitumor and anti-inflammatory activities.Colore e forma:Odour SolidPG-11047 2HCl
PG-11047 2HCl treats genitourinary, immune, genetic, ocular, blood/lymphatic disorders, and aids lymphoma/prostate cancer research.Formula:C14H34Cl2N4Purezza:99.51%Colore e forma:SolidPeso molecolare:329.35
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