Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(525 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(180 prodotti)
- Integrina(256 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(283 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(75 prodotti)
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Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"
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4',5'-Didehydro-5'-deoxy-5-methyluridine
CAS:4',5'-Didehydro-5'-deoxy-5-methyluridine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.Formula:C10H12N2O5Colore e forma:SolidPeso molecolare:240.21N1,N3-Bis(cyanomethyl)pseudouridine
N1,N3-Bis(cyanomethyl)pseudouridine is a Nucleoside Derivative - C-nucleoside;N-Alkylated nucleoside.Colore e forma:Soild3'-b-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine
CAS:3'-b-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine is a Nucleoside Derivative - Amino-nucleoside, Xylo-nucleoside, 2',3'-Didexoy nucleoside, 3'-ModifiedFormula:C29H29N3O5Colore e forma:SolidPeso molecolare:499.561-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose
CAS:<p>1-O-Acetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose is a Carbohydrate Derivative.</p>Formula:C29H32O6SiColore e forma:SolidPeso molecolare:504.652'-O-(2-Methoxyethyl)-2-aminoadenosine
CAS:Nucleoside Derivatives - 2’-Modified nucleosides, 2-Modified purine nucleosidesFormula:C13H20N6O5Colore e forma:SolidPeso molecolare:340.341-(3'-O-[4,4'-Dimethoxytrityl]-α-L-threofuranosyl)-thymine
CAS:Nucleoside Derivatives - L-Nucleosides; Protected nucleosides w/NH2/OH openFormula:C30H30N2O7Colore e forma:SolidPeso molecolare:530.57N4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-5-methylcytidine is a Nucleoside Derivative - Protected nucleoside w/NH2/OH open.Formula:C38H37N3O8Colore e forma:SolidPeso molecolare:663.729-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine
CAS:9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-ModifiedFormula:C16H15FN4O3Colore e forma:SolidPeso molecolare:330.31GDC-0575 dihydrochloride
CAS:GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is a selective, orally active CHK1 inhibitor (IC50: 1.2 nM) that exhibits antitumour effects.Formula:C16H22BrCl2N5OColore e forma:SolidPeso molecolare:451.194'-α-C-Allyl uridine
CAS:4'-alpha-C-Allyl uridine is a Nucleoside Derivative - 4'-Modified nucleoside.Formula:C12H16N2O6Colore e forma:SolidPeso molecolare:284.275-(1-Hydroxy)(methoxycarbonyl)methyl uridine
CAS:5-(1-Hydroxy)(methoxycarbonyl)methyl uridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Naturally modified ribo-nucleoside.Formula:C12H16N2O9Colore e forma:SolidPeso molecolare:332.26N6-Benzoyl-2'-deoxy-2',2'-diflurocytidine
CAS:N6-Benzoyl-2'-deoxy-2',2'-diflurocytidine is a Nucleoside Derivative - Fluoro-modified nucleoside.Formula:C16H15F2N3O5Colore e forma:SolidPeso molecolare:367.3N1-(1,1,1-Trifluoroethyl)pseudouridine
CAS:Nucleoside Derivatives - C-Nucleosides; N-Alkylated nucleosides; Fluoro-modified nucleosidesFormula:C11H13F3N2O6Colore e forma:SolidPeso molecolare:326.239-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine
CAS:9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purineFormula:C18H16FN5O3Colore e forma:SolidPeso molecolare:369.355'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine
CAS:Nucleoside Derivatives - 5-Modified pyrimidine nucleosideFormula:C31H32N2O9Colore e forma:SolidPeso molecolare:576.592,6-Bis(4-morpholinyl)-9-b-D-ribofuranosyl-9H-purine
Nucleoside Derivatives –6-Subtituted nucleosides；2-Substituted nucleosidesColore e forma:Soild2-Chloro-6-methoxypurine -9-β-D-(2'-deoxy-2'-fluoro)-arabinoriboside
CAS:Fluoro-modified nucleoside; Halo-nucleoside; 2/6/8-Modified purine nucleoside; Arabino-nucleoside;Formula:C11H12ClFN4O4Colore e forma:SolidPeso molecolare:318.695'-O-DMTr-2',2'-difluoro-dC(Bz)-3'-CED-phosphoramidite
CAS:Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; Nucleoside PhosphoramiditesFormula:C46H50F2N5O8PColore e forma:SolidPeso molecolare:869.898-Chloro-2'-β-C-methyl inosine
CAS:Nucleoside Derivatives - 2’-Modified nucleosides; 8-Modified purine nucleosides; Halo-nucleosidesFormula:C11H13ClN4O5Colore e forma:SolidPeso molecolare:316.72'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-β-D-arabinouridine
CAS:2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a Nucleoside Derivative - Fluoro-modified nucleoside,Arabino-nucleoside, 2'-Modified nucleoside.Formula:C16H16FN3O7Colore e forma:SolidPeso molecolare:381.313'-Azido-3'-deoxy-N6,N6-dimethyladenosine
CAS:3'-Azido-3'-deoxy-N6,N6-dimethyladenosine is a Nucleoside Derivative - Azido-nucleoside, 6-Modified purine nucleoside;N-Methylated nucleoside.Formula:C12H16N8O3Colore e forma:SolidPeso molecolare:320.319-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine
CAS:9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(pyridine-4-yl)purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-Formula:C15H14FN5O3Colore e forma:SolidPeso molecolare:331.35'(R)-C-Methyluridine
CAS:5'(R)-C-Methyluridine is a Nucleoside Derivative - 5'-Modified nucleoside.Formula:C10H14N2O6Colore e forma:SolidPeso molecolare:258.233'-O-(2-Methoxyethyl)cytidine
CAS:3'-O-(2-Methoxyethyl)cytidine is a Nucleoside Derivative - 3'-Modified nucleoside.Formula:C12H19N3O6Colore e forma:SolidPeso molecolare:301.35-Azidomethyl-2'-β-methyl-2',3',5'-tri-O-benzoyluridine
CAS:5-Azidomethyl-2'-beta-methyl-2',3',5'-tri-O-benzoyluridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Azido nucleoside; 2'-ModifiedFormula:C32H27N5O9Colore e forma:SolidPeso molecolare:625.59AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Formula:C24H32N6O3Purezza:97.84% - >99.99%Colore e forma:SolidPeso molecolare:452.55Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Formula:C18H22BrN5O3Purezza:98.86% - 99.87%Colore e forma:SolidPeso molecolare:436.3ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.596-Mercaptopurine hydrate
CAS:6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Formula:C5H6N4OSPurezza:97.54% - 99.14%Colore e forma:Light Yellow Crystalline PowderPeso molecolare:170.19iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purezza:98.77%Colore e forma:SolidPeso molecolare:948.04BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purezza:99.47% - 99.84%Colore e forma:SolidPeso molecolare:360.41TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Formula:C11H10Cl2N4Purezza:97.73% - 99%Colore e forma:SolidPeso molecolare:269.13Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formula:C23H25N5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:451.54Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formula:C27H26N6OPurezza:99.67%Colore e forma:SolidPeso molecolare:450.53Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purezza:98.49% - 98.93%Colore e forma:SolidPeso molecolare:421.49Camostat mesylate
CAS:Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.Formula:C21H26N4O8SPurezza:99.31% - 99.85%Colore e forma:Crystalline SolidPeso molecolare:494.52CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formula:C26H31BrN8OPurezza:98.51% - 99.89%Colore e forma:SolidPeso molecolare:551.48Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Formula:C21H31N7OPurezza:99.75%Colore e forma:SolidPeso molecolare:397.52ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Formula:C15H9F4N5OSPurezza:98.12%Colore e forma:SolidPeso molecolare:383.32PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formula:C24H27N3O4SPurezza:97.81%Colore e forma:SolidPeso molecolare:453.55ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Formula:C19H22O7SPurezza:98.27%Colore e forma:SolidPeso molecolare:394.44Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formula:C22H39ClN2O6SPurezza:98.81% - >99.99%Colore e forma:White SolidPeso molecolare:495.075-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Formula:C9H11BrN2O5Purezza:99.54% - 99.87%Colore e forma:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecolare:307.1MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurezza:98.80%Colore e forma:SolidPeso molecolare:377.46LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purezza:98.82%Colore e forma:SolidPeso molecolare:389.39Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purezza:99.74%Colore e forma:SolidPeso molecolare:274.32Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purezza:97.96% - 99.42%Colore e forma:SolidPeso molecolare:402.49Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Formula:C51H74N14O13Purezza:98%Colore e forma:SolidPeso molecolare:1091.24A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formula:C15H12N2OS2Purezza:98.07% - 98.52%Colore e forma:SolidPeso molecolare:300.4GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formula:C20H11Cl2NO4Purezza:98.23%Colore e forma:SolidPeso molecolare:400.21Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurezza:98.91%Colore e forma:SolidPeso molecolare:413.4TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purezza:98.98%Colore e forma:SolidPeso molecolare:474.33LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formula:C23H29ClN8OPurezza:100%Colore e forma:SolidPeso molecolare:469.022′-Deoxy-2′-fluoroguanosine
CAS:2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Formula:C10H12FN5O4Purezza:99.89%Colore e forma:SolidPeso molecolare:285.23BMS-5
CAS:BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formula:C17H14Cl2F2N4OSPurezza:98.01% - 99.88%Colore e forma:SolidPeso molecolare:431.29BMS-1001
CAS:BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formula:C35H34N2O7Purezza:98.43%Colore e forma:SolidPeso molecolare:594.7Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formula:C29H29FN3O9PPurezza:95.87%Colore e forma:SolidPeso molecolare:613.53Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Formula:C18H18FN5O2SPurezza:98.8%Colore e forma:SolidPeso molecolare:387.43Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purezza:98% - 99.8%Colore e forma:SolidPeso molecolare:588.66Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.55KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurezza:98.43% - 99.69%Colore e forma:SolidPeso molecolare:332.4Silver sulfadiazine
CAS:Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.Formula:C10H9AgN4O2SPurezza:99.04% - 99.58%Colore e forma:SolidPeso molecolare:357.14Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purezza:99.11%Colore e forma:SolidPeso molecolare:346.34YKL-5-124
CAS:YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displaysFormula:C28H33N7O3Purezza:99.36%Colore e forma:SolidPeso molecolare:515.61PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formula:C17H13Br2N5OS·HBrPurezza:99.91%Colore e forma:SolidPeso molecolare:576.1Bredinin aglycone
CAS:Bredinin aglycone (SM-108) is a purine nucleotide analog.Formula:C4H5N3O2Purezza:99.06%Colore e forma:SolidPeso molecolare:127.1WEE1-IN-3
CAS:WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.Formula:C28H31N7O2Purezza:98.33%Colore e forma:SolidPeso molecolare:497.59HALOFUGINONE LACTATE
CAS:HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formula:C19H23BrClN3O6Purezza:99.70% - 99.96%Colore e forma:SolidPeso molecolare:504.8dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purezza:99.64%Colore e forma:SolidPeso molecolare:507.182'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formula:C10H12FN5O3Purezza:99.95%Colore e forma:SolidPeso molecolare:269.23Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formula:C28H26Cl2N4O5Purezza:99.26% - 99.72%Colore e forma:SolidPeso molecolare:569.44Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Formula:C20H23CaN7O6Purezza:97.35%Colore e forma:Off-White To Pale Yellow SolidPeso molecolare:497.52AZD-7762
CAS:AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Formula:C17H19FN4O2SPurezza:98.96% - 99.19%Colore e forma:SolidPeso molecolare:362.42CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purezza:99.58%Colore e forma:SolidPeso molecolare:478.82Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formula:C27H32F2N8Purezza:99.43% - 99.87%Colore e forma:SolidPeso molecolare:506.59NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purezza:99.16% - 99.27%Colore e forma:SolidPeso molecolare:637.76NSC23005 Sodium
CAS:<p>NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.</p>Formula:C13H16NNaO4SPurezza:99.64%Colore e forma:SolidPeso molecolare:305.32BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurezza:99.21%Colore e forma:SolidPeso molecolare:416.99Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurezza:99.55%Colore e forma:SolidPeso molecolare:286.2NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purezza:99.78%Colore e forma:SolidPeso molecolare:400.04Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Purezza:97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%Colore e forma:LiquidPeso molecolare:N/AJNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formula:C15H12F2N6O3SPurezza:99.1% - 99.85%Colore e forma:SolidPeso molecolare:394.366-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Formula:C8H7BrO3Purezza:99.82%Colore e forma:SolidPeso molecolare:231.04Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurezza:97.45% - 99.4%Colore e forma:SolidPeso molecolare:559.614μ8C
CAS:4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.Formula:C11H8O4Purezza:97.48% - 98.45%Colore e forma:SolidPeso molecolare:204.18Isoindigotin
CAS:<p>Isoindigotin is used in the therapy of Y.</p>Formula:C16H10N2O2Purezza:98.14% - ≥95%Colore e forma:SolidPeso molecolare:262.26Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Formula:C31H35Cl3N8O5Purezza:99.69%Colore e forma:SolidPeso molecolare:706.026-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Formula:C10H12N4O4SPurezza:97.74%Colore e forma:SolidPeso molecolare:284.29CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purezza:98.82% - 99.50%Colore e forma:SolidPeso molecolare:408.88RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purezza:99.3% - 99.62%Colore e forma:SolidPeso molecolare:361.61TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formula:C72H66N8O12S4Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:1363.6Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purezza:98%Colore e forma:SolidPeso molecolare:596.64Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purezza:98.65% - 99.86%Colore e forma:SolidPeso molecolare:500.6CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formula:C14H12N6O2SPurezza:99.54%Colore e forma:SolidPeso molecolare:328.35Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurezza:98.68% - 99.64%Colore e forma:SolidPeso molecolare:401.46Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:543.61HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purezza:99.96%Colore e forma:SolidPeso molecolare:263.29IMT1B
CAS:<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Formula:C24H21ClFNO6Purezza:98.26% - 99.83%Colore e forma:SolidPeso molecolare:473.88
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