Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(525 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(224 prodotti)
- HSP(180 prodotti)
- Integrina(256 prodotti)
- Chinesina(86 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(284 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(75 prodotti)
Mostrare 10 più sottocategorie
Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"
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3-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Formula:C10H15N3O5Purezza:99.52%Colore e forma:SolidPeso molecolare:257.24SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formula:C18H15ClN6OS2Purezza:98%Colore e forma:SolidPeso molecolare:430.93(1E)-CFI-400437 dihydrochloride
CAS:(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.Formula:C29H30Cl2N6O2Purezza:97.08%Colore e forma:SolidPeso molecolare:565.5Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurezza:98% - 99.45%Colore e forma:SolidPeso molecolare:393.49TH-257
CAS:TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).Formula:C24H26N2O3SPurezza:98.23%Colore e forma:SolidPeso molecolare:422.54Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Formula:C29H32N4O3SPurezza:98.04% - 99.44%Colore e forma:SolidPeso molecolare:516.65Trimethoprim sulfate
CAS:Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.Formula:C28H38N8O10SColore e forma:SolidPeso molecolare:678.72CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purezza:98.27% - 98.98%Colore e forma:Brown PowderPeso molecolare:206.155-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formula:C5H3FN2O4Purezza:99.7% - >99.99%Colore e forma:White To Pale Yellow PowderPeso molecolare:174.09RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purezza:99.63% - 99.86%Colore e forma:SolidPeso molecolare:433.28Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Formula:C35H33FN6O3Purezza:99.77%Colore e forma:SolidPeso molecolare:604.67MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formula:C15H9NO3Purezza:98.6%Colore e forma:SolidPeso molecolare:251.24LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formula:C29H48N12O12S2Purezza:>99.99%Colore e forma:SolidPeso molecolare:820.89POL1-IN-1
CAS:<p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>Formula:C21H20N6Purezza:98% - 98.01%Colore e forma:SolidPeso molecolare:356.42Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H21ClFN3O4Purezza:99.78% - 99.98%Colore e forma:SolidPeso molecolare:397.8Acelarin
CAS:<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Formula:C25H27F2N4O8PPurezza:99.26%Colore e forma:SolidPeso molecolare:580.47Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purezza:97.96% - 99.42%Colore e forma:SolidPeso molecolare:402.49Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purezza:99.74%Colore e forma:SolidPeso molecolare:274.32CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurezza:97.36% - 97.59%Colore e forma:SolidPeso molecolare:368.46Dalpiciclib
CAS:<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Formula:C25H30N6O2Purezza:99.69%Colore e forma:SolidPeso molecolare:446.54Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formula:C22H39ClN2O6SPurezza:98.81% - >99.99%Colore e forma:White SolidPeso molecolare:495.07Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurezza:99.00% - 99.86%Colore e forma:SolidPeso molecolare:482.55Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Formula:C17H24ClNO4Purezza:99.75%Colore e forma:SolidPeso molecolare:341.83Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Formula:C41H44N4O10SPurezza:98.11%Colore e forma:SolidPeso molecolare:784.87SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purezza:98.13% - 98.47%Colore e forma:SolidPeso molecolare:450.6DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Formula:C41H49N4O9PPurezza:98.28%Colore e forma:SolidPeso molecolare:772.82M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formula:C20H16ClN5O2Purezza:98.01%Colore e forma:SolidPeso molecolare:393.83BMS-1166
CAS:<p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>Formula:C36H33ClN2O7Purezza:99.22%Colore e forma:SolidPeso molecolare:641.11SCH900776
CAS:SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Formula:C15H18BrN7Purezza:96.69% - 99.6%Colore e forma:SolidPeso molecolare:376.25Roniciclib
CAS:<p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>Formula:C18H21F3N4O3SPurezza:98% - 98.63%Colore e forma:SolidPeso molecolare:430.44LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formula:C17H25F2N3O5Purezza:98.82%Colore e forma:SolidPeso molecolare:389.39MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurezza:98.80%Colore e forma:SolidPeso molecolare:377.46GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurezza:99.4% - 99.70%Colore e forma:SolidPeso molecolare:595.712'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Formula:C9H12FN3O4Purezza:99.90%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:245.21BS-181 dihydrochloride
CAS:BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.Formula:C22H34Cl2N6Colore e forma:SolidPeso molecolare:453.46PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurezza:98.77% - 99.55%Colore e forma:SolidPeso molecolare:471.52AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Formula:C18H21N5O2SPurezza:99.73% - 99.87%Colore e forma:SolidPeso molecolare:371.46CRT0066854
CAS:CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.Formula:C24H25N5SColore e forma:SolidPeso molecolare:415.55Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurezza:98.01%Colore e forma:SolidPeso molecolare:244.29Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Formula:C36H62O9Purezza:98.62% - 99.71%Colore e forma:SolidPeso molecolare:638.875-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Formula:C9H11BrN2O5Purezza:99.54% - 99.87%Colore e forma:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecolare:307.1TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Formula:C19H18BrIN4O2Purezza:98.38% - 98.73%Colore e forma:SolidPeso molecolare:541.18360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formula:C27H23N5O2Purezza:98.68%Colore e forma:SolidPeso molecolare:449.5InhA-IN-2
CAS:N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.Formula:C16H15ClN2O2S2Purezza:98.4%Colore e forma:SolidPeso molecolare:366.89Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurezza:97.15% - 99.89%Colore e forma:White To Off-White SolidPeso molecolare:354.45Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Formula:C9H11ClN4O2Purezza:99.815%Colore e forma:SolidPeso molecolare:242.66Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Formula:C13H10ClN3OPurezza:99.42% - 99.87%Colore e forma:SolidPeso molecolare:259.69XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurezza:99.07%Colore e forma:SolidPeso molecolare:437.54Ibezapolstat
CAS:Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Formula:C18H20Cl2N6O2Purezza:98% - 99.429%Colore e forma:SolidPeso molecolare:423.3Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurezza:99.99%Colore e forma:SolidPeso molecolare:464.595'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Formula:C9H12FN3O4Purezza:99.67%Colore e forma:White SolidPeso molecolare:245.21SAR-020106
CAS:SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.Formula:C19H19ClN6OPurezza:97.78%Colore e forma:SolidPeso molecolare:382.85Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Formula:C23H29Cl2N3OPurezza:99.46%Colore e forma:SolidPeso molecolare:434.4Tipiracil hydrochloride
CAS:Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formula:C9H12Cl2N4O2Purezza:98.13% - ≥95%Colore e forma:SolidPeso molecolare:279.12THZ2
CAS:THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Formula:C31H28ClN7O2Purezza:98.28%Colore e forma:SolidPeso molecolare:566.05IRE1α kinase-IN-1
CAS:<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Formula:C26H26ClFN8Purezza:99.18%Colore e forma:SolidPeso molecolare:504.996-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Formula:C10H12N4O4SPurezza:97.74%Colore e forma:SolidPeso molecolare:284.29CX-5461 dihydrochloride
CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).Formula:C27H29Cl2N7O2SColore e forma:SolidPeso molecolare:586.54CCG-203971
CAS:CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.Formula:C23H21ClN2O3Purezza:98.82% - 99.50%Colore e forma:SolidPeso molecolare:408.88Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Formula:C16H17N5O2Purezza:99.06% - 99.61%Colore e forma:SolidPeso molecolare:311.34Cedazuridine hydrochloride
Cedazuridine (E7727) hydrochloride is an oral cancer research drug blocking cytidine deaminase (IC50=0.4μM).Formula:C9H15ClF2N2O5Colore e forma:SolidPeso molecolare:304.68FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurezza:98.61%Colore e forma:SolidPeso molecolare:315.41Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurezza:98.07%Colore e forma:SolidPeso molecolare:302.39RI-1
CAS:RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).Formula:C14H11Cl3N2O3Purezza:99.3% - 99.62%Colore e forma:SolidPeso molecolare:361.61TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formula:C72H66N8O12S4Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:1363.6SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purezza:99.88%Colore e forma:SolidPeso molecolare:376.25Folinic acid calcium hydrate
CAS:Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.Formula:C20H23CaN7O8Colore e forma:SolidPeso molecolare:529.523Netarsudil free base
CAS:Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formula:C28H27N3O3Colore e forma:SolidPeso molecolare:453.53Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purezza:98%Colore e forma:SolidPeso molecolare:596.64THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formula:C30H32ClN7O2Purezza:97.17% - 99.86%Colore e forma:SolidPeso molecolare:558.072'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formula:C10H12FN5O3Purezza:99.95%Colore e forma:SolidPeso molecolare:269.23Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFormula:C25H23FN4OPurezza:98.38%Colore e forma:SolidPeso molecolare:414.47AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Formula:C17H16ClN3OPurezza:98.04% - ≥95%Colore e forma:SolidPeso molecolare:313.78NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Formula:C16H19ClN6OPurezza:98% - 99.34%Colore e forma:SolidPeso molecolare:346.81Calcium N5-methyltetrahydrofolate
CAS:<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Formula:C20H23CaN7O6Purezza:99.41%Colore e forma:SolidPeso molecolare:497.51IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purezza:97.73%Colore e forma:SolidPeso molecolare:485.45Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purezza:98.65% - 99.86%Colore e forma:SolidPeso molecolare:500.6CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formula:C14H12N6O2SPurezza:99.54%Colore e forma:SolidPeso molecolare:328.35EN4
CAS:EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Formula:C25H24N2O4Purezza:98.51%Colore e forma:SolidPeso molecolare:416.47dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purezza:99.64%Colore e forma:SolidPeso molecolare:507.18Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Formula:C11H10Cl2N4Purezza:97.73% - 99%Colore e forma:SolidPeso molecolare:269.13Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formula:C23H25N5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:451.54AZD-7762
CAS:AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Formula:C17H19FN4O2SPurezza:98.96% - 99.19%Colore e forma:SolidPeso molecolare:362.42Mitonafide
CAS:<p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>Formula:C16H15N3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:313.31Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formula:C27H26N6OPurezza:99.67%Colore e forma:SolidPeso molecolare:450.53CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formula:C18H17F3N6O2Purezza:99.50%Colore e forma:SolidPeso molecolare:406.36CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Formula:C28H28N6O4Purezza:98.66% - 98.8%Colore e forma:SolidPeso molecolare:512.56RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurezza:99.95%Colore e forma:SolidPeso molecolare:373.83Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Formula:C19H20FN3O3Purezza:99.77% - 99.8%Colore e forma:SolidPeso molecolare:357.38CBFβ Inhibitor
CAS:<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Formula:C12H14N2OSPurezza:96.50%Colore e forma:SolidPeso molecolare:234.32Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurezza:97.51% - 99.51%Colore e forma:SolidPeso molecolare:427.32NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurezza:98.03% - 99.46%Colore e forma:SolidPeso molecolare:433.48Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formula:C20H21N7O7·CaPurezza:99.07% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:511.5Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurezza:98.68% - 99.64%Colore e forma:SolidPeso molecolare:401.46Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Formula:C12H13FN4O5Colore e forma:SolidPeso molecolare:312.257AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purezza:99.83% - 99.98%Colore e forma:SolidPeso molecolare:381.43Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:543.61GDC-0575
CAS:<p>GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).</p>Formula:C16H20BrN5OPurezza:≥95%Colore e forma:SolidPeso molecolare:378.27Apcin-A
CAS:Apcin-A is an anaphase-promoting complex (APC) inhibitor.Formula:C10H14Cl3N5O2Colore e forma:SolidPeso molecolare:342.61
