Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(526 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(179 prodotti)
- Integrina(256 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(283 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3756 prodotti di "Ciclo cellulare/Checkpoint"
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Phelorphan
CAS:Phelorphan is an inhibitor of enkephalinase.Formula:C20H22N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:386.46CDK7-IN-15
CAS:CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.Formula:C21H24F4N6OSPurezza:99.27%Colore e forma:SolidPeso molecolare:484.51CDK7-IN-13
CAS:CDK7-IN-13 (compound 1) is an effective CDK7 inhibitor for investigating cancers associated with transcriptional dysregulation.Formula:C20H23F3N6OSPurezza:99.22%Colore e forma:SolidPeso molecolare:452.5Indirubin-3'-monoxime-5-sulphonic acid
CAS:Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.Formula:C16H11N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:357.34CDK7-IN-16
CAS:CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Formula:C19H21F3N6O2SColore e forma:SolidPeso molecolare:454.47Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Formula:C22H21N3O5S2Purezza:98.79%Colore e forma:SolidPeso molecolare:471.55SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurezza:98%Colore e forma:SolidPeso molecolare:319.81CFM-1
CAS:CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.Formula:C12H7BrN2O2S2Purezza:98%Colore e forma:SolidPeso molecolare:355.23Synucleozid
CAS:Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Formula:C22H20N6Purezza:98%Colore e forma:SolidPeso molecolare:368.43GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormula:C18H30Cl3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:454.82MMV688845
CAS:MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Formula:C24H25N3O3SColore e forma:SolidPeso molecolare:435.54PF-4950834
CAS:PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.Formula:C21H19N3O2Purezza:98%Colore e forma:SolidPeso molecolare:345.39MMV688844
CAS:MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Formula:C23H25ClN4O2Colore e forma:SolidPeso molecolare:424.92RUC-1
CAS:RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.Formula:C11H15N5OSPurezza:98%Colore e forma:SolidPeso molecolare:265.33Homocarbonyltopsentin
CAS:Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.Formula:C21H14N4O3Purezza:98%Colore e forma:SolidPeso molecolare:370.36Guanoctine hydrochloride
CAS:Guanoctine hydrochloride has antihypertensive activity.Formula:C9H22ClN3Colore e forma:SolidPeso molecolare:207.74PV-1115
CAS:PV-1115 is an effective and highly selective inhibitor of the Chk2.Formula:C20H19N7O3Purezza:98%Colore e forma:SolidPeso molecolare:405.41Cdc7-IN-9
CAS:Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].Formula:C15H17N5OSColore e forma:SolidPeso molecolare:315.39IXA6
CAS:IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formula:C22H20ClN3O3SPurezza:98.63%Colore e forma:SolidPeso molecolare:441.93JH-XIV-68-3
CAS:JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.Formula:C21H17F3N8OColore e forma:SolidPeso molecolare:454.41MTH1-IN-2
CAS:<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formula:C24H27N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:469.55L-Cytidine
CAS:L-Cytidine, pyrimidine nucleoside in RNA, regulates glial glutamate, brain lipids, catecholamines, and mitochondria.Formula:C9H13N3O5Colore e forma:SolidPeso molecolare:243.22Metioprim
CAS:Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.Formula:C14H18N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:306.38FRα-IN-1
CAS:FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.Formula:C21H24N6O6Colore e forma:SolidPeso molecolare:456.45IDD388
CAS:IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formula:C16H12BrClFNO4Purezza:99.56%Colore e forma:SolidPeso molecolare:416.63A 65282
CAS:A 65282: antibacterial isothiazoloquinolone, inhibits P4-unknotting, causes DNA breaks via topoisomerase II.Formula:C17H16F2N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:378.4Clociguanil
CAS:Clociguanil has antimalarial activity.Formula:C12H15Cl2N5OColore e forma:SolidPeso molecolare:316.19Erythromycin hydrochloride
CAS:Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.Formula:C37H68ClNO13Colore e forma:SolidPeso molecolare:770.39Digeranyl bisphosphonate
CAS:Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.DigeranylFormula:C21H34Na4O6P2Purezza:98.5%Colore e forma:SolidPeso molecolare:536.4CLK1-IN-1
CAS:CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).Formula:C24H16FN5OColore e forma:SolidPeso molecolare:409.42GW8510
CAS:GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Formula:C21H15N5O3S2Purezza:99.32%Colore e forma:SolidPeso molecolare:449.51THZ1-R
CAS:THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.Formula:C31H30ClN7O2Purezza:98%Colore e forma:SolidPeso molecolare:568.07Mequindox
CAS:Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].Formula:C11H10N2O3Colore e forma:SolidPeso molecolare:218.21DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Colore e forma:SolidPeso molecolare:394.51Phen-DC3
CAS:Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).Formula:C34H26N6O2Purezza:98%Colore e forma:SolidPeso molecolare:550.61RP-106
CAS:RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.Formula:C17H19N3OPurezza:98%Colore e forma:SolidPeso molecolare:281.35Antitumor agent-84
Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.Formula:C24H31N7Colore e forma:SolidPeso molecolare:417.55Nucleoside-Analog-2
CAS:Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.Formula:C9H11N5O6Purezza:98%Colore e forma:SolidPeso molecolare:285.21TCS 2312
CAS:checkpoint kinase 1 (chk1) inhibitorFormula:C25H24N4O2Purezza:98%Colore e forma:SolidPeso molecolare:412.48Trimetrexate
CAS:Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.Formula:C19H23N5O3Purezza:98%Colore e forma:SolidPeso molecolare:369.42Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Formula:C15H13F3N2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:310.27ANI-7
CAS:ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).Formula:C13H8Cl2N2Purezza:99.07%Colore e forma:SolidPeso molecolare:263.12CRT5
CAS:CRT5, a selective PKD inhibitor, blocks VEGF effects on histone deacetylase 5, CREB, HSP27, and endothelial functions. IC50s: 1-2 nM for PKD1-3.Formula:C28H30N4O2Colore e forma:SolidPeso molecolare:454.56BAP1-IN-1
CAS:BAP1-IN-1 is an inhibitor of the catalytic activity of BRCA1-associated protein 1 (BAP1), which is related to cancer and can be used to study cancer.Formula:C18H16N2O2Purezza:98.11%Colore e forma:SolidPeso molecolare:292.331-Methylcytosine
CAS:<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Formula:C5H7N3OPurezza:99.88%Colore e forma:SolidPeso molecolare:125.13Integrin-IN-2
CAS:Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.Formula:C27H30N4O3Purezza:98%Colore e forma:SolidPeso molecolare:458.55Cyclapolin 9
CAS:Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.Formula:C9H4F3N3O4SPurezza:99.64%Colore e forma:SolidPeso molecolare:307.21Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formula:C20H22N4O5SPurezza:99.39% - 99.39%Colore e forma:SolidPeso molecolare:430.48BAY-707 acetate
CAS:BAY-707: potent, selective MTH1 inhibitor with excellent engagement and pharmacokinetics but no anticancer efficacy alone or combined.Formula:C17H24N4O4Colore e forma:SolidPeso molecolare:348.18TIBI
CAS:TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme.Formula:C7H2I4N2Purezza:>99.99%Colore e forma:SolidPeso molecolare:621.72Ulecaciclib
CAS:Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).Formula:C25H33FN8SColore e forma:SolidPeso molecolare:496.65KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formula:C28H38N4O5S2Purezza:98.45%Colore e forma:SolidPeso molecolare:574.76Ametantrone Acetate
CAS:Ametantrone Acetate is a topoisomerase II inhibitor of anthrapyrazole family, which can lead to DNA covalent crosslinking.Formula:C24H32N4O6Colore e forma:SolidPeso molecolare:472.542Mycro1
CAS:Mycro1 is an inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max.Formula:C20H15F3N4O2SColore e forma:SolidPeso molecolare:432.42360A iodide
CAS:360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).Formula:C27H23I2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:703.31NSC 625987
CAS:Cyclin-dependent kinase (cdk) 4 inhibitorFormula:C15H13NO2SPurezza:98%Colore e forma:SolidPeso molecolare:271.33RECQL5-IN-1
CAS:RECQL5-IN-1, an oral RECQL5 inhibitor (IC50 46.3 nM), targets enzyme/non-enzyme domains, useful in breast cancer research.Formula:C25H18F6N4O2SColore e forma:SolidPeso molecolare:552.49PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:554.08PD 130883
CAS:PD 130883 is a potent lipophilic quinazoline antifolate.Formula:C18H15N5O3Purezza:98%Colore e forma:SolidPeso molecolare:349.34Direct Black 38 free acid
CAS:Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.Formula:C34H27N9O7S2Purezza:98%Colore e forma:SolidPeso molecolare:737.77Chlorasquin
CAS:Chlorasquin is a dihydrofolate reductase inhibitor.Formula:C20H19ClN6O5Purezza:98%Colore e forma:SolidPeso molecolare:458.868-Deazahomofolic acid
CAS:8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.Formula:C21H22N6O6Purezza:98%Colore e forma:SolidPeso molecolare:454.44S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.Formula:C12H16N2O2S2Colore e forma:SolidPeso molecolare:284.4N2-Ethylguanosine
CAS:N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.Formula:C12H17N5O5Colore e forma:SolidPeso molecolare:311.29PFM03
CAS:PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.Formula:C14H15NO2S2Purezza:99.81% - 99.98%Colore e forma:SolidPeso molecolare:293.4UR-3216
CAS:UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.Formula:C27H29N7O7Purezza:98%Colore e forma:SolidPeso molecolare:563.56Apricitabine
CAS:Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-Formula:C8H11N3O3SPurezza:99.45%Colore e forma:SolidPeso molecolare:229.26CLT-28643
CAS:CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Formula:C19H17N3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:351.36XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Formula:C21H24N8OPurezza:99.04%Colore e forma:SoildPeso molecolare:404.47CDK8/19-IN-51
CAS:CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formula:C23H22N6O2Purezza:98.65% - 99.62%Colore e forma:SoildPeso molecolare:414.46XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formula:C25H21Cl2N3O8Colore e forma:SolidPeso molecolare:562.3610-Methyl-10-deazaaminopterin
CAS:10-Methyl-10-deazaaminopterin is a folate analog that shows antitumor activity.Formula:C21H23N7O5Purezza:98%Colore e forma:SolidPeso molecolare:453.45FN-1501-propionic acid
CAS:FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.Formula:C25H27N9O4Purezza:98%Colore e forma:SolidPeso molecolare:517.54ROCK-IN-D2
CAS:ROCK-IN-D2 is an effective and selective inhibitor of ROCK.Formula:C22H28N6OPurezza:98%Colore e forma:SolidPeso molecolare:392.5Cdc7-IN-13
CAS:Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Formula:C18H20N4O2SColore e forma:SolidPeso molecolare:356.44CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Formula:C24H26N2O2Purezza:98.18% - 98.86%Colore e forma:SolidPeso molecolare:374.48AP-1/NF-κB activation inhibitor 1
CAS:AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFormula:C13H11F3N4O4Purezza:99.52% - 99.91%Colore e forma:SolidPeso molecolare:344.25UR-2922
CAS:UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.Formula:C25H25N7O6Purezza:98%Colore e forma:SolidPeso molecolare:519.51SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formula:C27H24N4O4Colore e forma:SolidPeso molecolare:468.5CDK2-IN-13
CAS:CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.Formula:C13H12ClN5Colore e forma:SoildPeso molecolare:273.72CDK8-IN-7
CAS:CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Formula:C30H40N2Colore e forma:SolidPeso molecolare:428.65EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:476.53GSK3182571
CAS:GSK3182571 is a non-speci c kinase inhibitor[1].Formula:C25H31ClN8OColore e forma:SolidPeso molecolare:495.02APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purezza:99.8%Colore e forma:SolidPeso molecolare:440.5Cdc7-IN-3
CAS:Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.Formula:C20H22N4O5Purezza:98%Colore e forma:SolidPeso molecolare:398.41AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Formula:C26H35N5O5SPurezza:98.06% - 99.58%Colore e forma:SolidPeso molecolare:529.65DHODH-IN-15
CAS:DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Formula:C15H11N3O3Purezza:99.8%Colore e forma:SolidPeso molecolare:281.27DNA Gyrase-IN-3
CAS:DNA Gyrase-IN-3 inhibits E. coli DNA gyrase B with IC50 5.41-15.64 μM; shows anti-TB and antibacterial properties.Formula:C18H20N6OS2Colore e forma:SolidPeso molecolare:400.52HOI-07
CAS:HOI-07 is a specific Aurora B inhibitor.Formula:C19H13NO4Colore e forma:SolidPeso molecolare:319.31RHI002-Me
CAS:RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.Formula:C18H19N3O2S2Purezza:98%Colore e forma:SolidPeso molecolare:373.49AG-012986
CAS:AG-012986: a selective CDK inhibitor with in vitro and in vivo antitumor effects; low IC50 in 14/18 cancer cell types; CAS# 486414-35-1.Formula:C22H23F2N5O2SColore e forma:SolidPeso molecolare:459.51Y-33075
CAS:Y-33075 (Y-39983 free base) is a ROCK inhibitor that lowers IOP, increases blood flow to ONH, and increases the number of RGCs with regenerating axons.Formula:C16H16N4OPurezza:98%Colore e forma:SolidPeso molecolare:280.32CB 3731
CAS:CB 3731 is used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.Formula:C23H24FN5O6Colore e forma:SolidPeso molecolare:485.46tBID
CAS:tBID is a selective homeodomain-interacting protein kinase 2 (HIPK2) inhibitor (IC50 of 0.33 μM)Formula:C11H3Br4N3O2Purezza:98%Colore e forma:SolidPeso molecolare:528.78Chlorozotocin
CAS:Chlorozotocin is a nitrosourea. It is used for cancer therapy.Formula:C9H16ClN3O7Colore e forma:SolidPeso molecolare:313.693'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formula:C9H15N2O14P3Colore e forma:SolidPeso molecolare:468.14IS-741 calcium
CAS:IS-741 calcium is a phospholipase A2 inhibitor.Formula:C30H38CaF6N6O6S2Colore e forma:SolidPeso molecolare:796.86DAP-81
CAS:DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.Formula:C25H20N6O4Colore e forma:SolidPeso molecolare:468.46CDK4/6-IN-9
CAS:CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.Formula:C22H23FN8Colore e forma:SolidPeso molecolare:418.47HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Formula:C22H20ClNO4Colore e forma:SolidPeso molecolare:397.85
