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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

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Trovati 3749 prodotti di "Ciclo cellulare/Checkpoint"

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  • SNX2-1-108

    CAS:
    SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.
    Formula:C21H16N4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:324.38
  • LIMK-IN-14

    CAS:
    LIMK-IN-14 is an effective and selective inhibitor of LIMK.
    Formula:C22H27N7O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:437.49
  • N2-Ethylguanosine

    CAS:
    N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.
    Formula:C12H17N5O5
    Colore e forma:Solid
    Peso molecolare:311.29
  • S-(N-PhenethylthiocarbaMoyl)-L-cysteine

    CAS:
    PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.
    Formula:C12H16N2O2S2
    Colore e forma:Solid
    Peso molecolare:284.4
  • Denopterin

    CAS:
    Denopterin is an antineoplastic agent.
    Formula:C21H23N7O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:469.45
  • 8-Deazahomofolic acid

    CAS:
    8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.
    Formula:C21H22N6O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:454.44
  • Direct Black 38 free acid

    CAS:
    Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.
    Formula:C34H27N9O7S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:737.77
  • ProTAME

    CAS:
    ProTAME inhibits APC/CFzr & APC/CCdc20, enhances cell death with doxorubicin/etoposide in primary/MM cells, especially after TOPIIα upregulation.
    Formula:C34H38N4O12S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:726.75
  • 1-Acetyl-3-o-toluyl-5-fluorouracil

    CAS:
    <p>1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.</p>
    Formula:C14H11FN2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:290.25
  • RET-IN-19

    CAS:
    RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.
    Formula:C28H28N6O4S
    Colore e forma:Solid
    Peso molecolare:544.62
  • PF-2771

    CAS:
    PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
    Formula:C29H36ClN5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:554.08
  • Cyclapolin 9

    CAS:
    Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.
    Formula:C9H4F3N3O4S
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:307.21
  • 1-Methylcytosine

    CAS:
    <p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>
    Formula:C5H7N3O
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:125.13
  • CRT5

    CAS:
    CRT5, a selective PKD inhibitor, blocks VEGF effects on histone deacetylase 5, CREB, HSP27, and endothelial functions. IC50s: 1-2 nM for PKD1-3.
    Formula:C28H30N4O2
    Colore e forma:Solid
    Peso molecolare:454.56
  • ANI-7

    CAS:
    ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).
    Formula:C13H8Cl2N2
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:263.12
  • Rabacfosadine succinate

    CAS:
    Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.
    Formula:C25H41N8O10P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:644.623
  • Thiamiprine

    CAS:
    Thiamiprine is an agent with the activity of antineoplastic.
    Formula:C9H8N8O2S
    Colore e forma:Solid
    Peso molecolare:292.28
  • GW8510

    CAS:
    GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.
    Formula:C21H15N5O3S2
    Purezza:99.32%
    Colore e forma:Solid
    Peso molecolare:449.51
  • Meturedepa

    CAS:
    Meturedepa is an antineoplastic agent.
    Formula:C11H22N3O3P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:275.28
  • Digeranyl bisphosphonate

    CAS:
    Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl
    Formula:C21H34Na4O6P2
    Purezza:98.5%
    Colore e forma:Solid
    Peso molecolare:536.4
  • (R)-Filanesib

    CAS:
    (R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
    Formula:C20H22F2N4O2S
    Colore e forma:Solid
    Peso molecolare:420.48
  • Clociguanil

    CAS:
    Clociguanil has antimalarial activity.
    Formula:C12H15Cl2N5O
    Colore e forma:Solid
    Peso molecolare:316.19
  • IDD388

    CAS:
    IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.
    Formula:C16H12BrClFNO4
    Purezza:99.56%
    Colore e forma:Solid
    Peso molecolare:416.63
  • CDK4/6-IN-8

    CAS:
    CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).
    Formula:C18H18N6O5
    Colore e forma:Solid
    Peso molecolare:398.37
  • IMB-10

    CAS:
    IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.
    Formula:C19H15NOS2
    Colore e forma:Solid
    Peso molecolare:337.46
  • FRα-IN-1

    CAS:
    FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.
    Formula:C21H24N6O6
    Colore e forma:Solid
    Peso molecolare:456.45
  • Metioprim

    CAS:
    Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.
    Formula:C14H18N4O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:306.38
  • L-Cytidine

    CAS:
    L-Cytidine, pyrimidine nucleoside in RNA, regulates glial glutamate, brain lipids, catecholamines, and mitochondria.
    Formula:C9H13N3O5
    Colore e forma:Solid
    Peso molecolare:243.22
  • USP28-IN-2

    CAS:
    USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.
    Formula:C23H20Cl2N2O3S
    Colore e forma:Solid
    Peso molecolare:475.39
  • ROCK-IN-4

    CAS:
    ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.
    Formula:C20H26ClFN4O7S
    Colore e forma:Solid
    Peso molecolare:520.96
  • TCS 2314

    CAS:
    TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).
    Formula:C28H34N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:522.59
  • Trimetrexate glucuronate

    CAS:
    Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.
    Formula:C25H33N5O10
    Colore e forma:Solid
    Peso molecolare:563.564
  • Aloisine A

    CAS:
    Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.
    Formula:C16H17N3O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:267.33
  • CDK4/6-IN-14

    CAS:
    CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.
    Formula:C24H27ClFN7O
    Colore e forma:Solid
    Peso molecolare:483.97
  • CI-898 HCl

    CAS:
    CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.
    Formula:C19H26Cl3N5O3
    Colore e forma:Solid
    Peso molecolare:478.8
  • XIE18-6

    CAS:
    XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.
    Formula:C18H15NO6S
    Purezza:99.712%
    Colore e forma:Solid
    Peso molecolare:373.38
  • BA-1049

    CAS:
    BA-1049 is a selective ROCK2 inhibitor.
    Formula:C16H21N3O2S
    Colore e forma:Solid
    Peso molecolare:319.42
  • WF-536 Hydrochloride

    CAS:
    WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.
    Formula:C14H16ClN3O
    Colore e forma:Solid
    Peso molecolare:277.75
  • LY 207702

    CAS:
    LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.
    Formula:C10H12F2N6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:302.24
  • IRE1α kinase-IN-7

    CAS:
    IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic
    Formula:C28H25F3N6O
    Colore e forma:Solid
    Peso molecolare:518.53
  • DNA Gyrase-IN-4

    CAS:
    DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.
    Formula:C22H15Cl2NO4S
    Colore e forma:Solid
    Peso molecolare:460.33
  • Codon readthrough inducer 1

    CAS:
    Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.
    Formula:C15H11N3O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:313.26
  • Binucleine 2

    CAS:
    Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.
    Formula:C13H11ClFN5
    Colore e forma:Solid
    Peso molecolare:291.71
  • FUBP1-IN-2

    CAS:
    FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.
    Formula:C26H26ClN3O4
    Colore e forma:Solid
    Peso molecolare:479.96
  • MS0017509

    CAS:
    MS0017509 is a DNA damage repair inhibitor.
    Formula:C11H10N4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:198.22
  • Cylindrospermopsin

    CAS:
    Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.
    Formula:C15H21N5O7S
    Colore e forma:Solid
    Peso molecolare:415.42
  • MDK6204

    CAS:
    MDK6204 is a selective inhibitor of CLK1 and CLK2.
    Formula:C20H20N6O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:360.41
  • Zalunfiban

    CAS:
    RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.
    Formula:C16H18N8O2S
    Colore e forma:Solid
    Peso molecolare:386.43
  • Syntelin

    CAS:
    Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.
    Formula:C21H20N6O2S3
    Colore e forma:Solid
    Peso molecolare:484.62
  • DNA Gyrase-IN-5

    CAS:
    DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.
    Formula:C25H15BrClN5
    Colore e forma:Solid
    Peso molecolare:500.78
  • BSJ-01-175

    CAS:
    BSJ-01-175: Selective, potent covalent inhibitor of CDK12/13, targets cancer cells, inhibits phosphorylated RNA polymerase II, downregulates CDK12 genes.
    Formula:C30H33ClN6O2
    Colore e forma:Solid
    Peso molecolare:545.08
  • DENV-IN-7

    CAS:
    DENV-IN-7, a flavone analog, inhibits dengue virus at 70 nM EC50 with low toxicity to normal cells.
    Formula:C24H22O8
    Colore e forma:Solid
    Peso molecolare:438.43
  • P1788

    CAS:
    P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].
    Formula:C15H17NO3
    Colore e forma:Solid
    Peso molecolare:259.3
  • 5,10-Dideazaaminopterin

    CAS:
    5,10-Dideazaaminopterin is an antileukemic drug.
    Formula:C21H22N6O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:438.44
  • Antibacterial agent 89

    CAS:
    Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.
    Formula:C21H10Cl2F3NO5S
    Colore e forma:Solid
    Peso molecolare:516.27
  • HBV-IN-14

    CAS:
    HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).
    Formula:C22H21ClN2O5
    Colore e forma:Solid
    Peso molecolare:428.87
  • BMH-23

    CAS:
    BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.
    Formula:C15H15N3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:237.3
  • Indirubin-3'-monoxime-5-sulphonic acid

    CAS:
    Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.
    Formula:C16H11N3O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:357.34
  • MMV688845

    CAS:
    MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.
    Formula:C24H25N3O3S
    Colore e forma:Solid
    Peso molecolare:435.54
  • CDK7-IN-13

    CAS:
    CDK7-IN-13 (compound 1) is an effective CDK7 inhibitor for investigating cancers associated with transcriptional dysregulation.
    Formula:C20H23F3N6OS
    Purezza:99.22%
    Colore e forma:Solid
    Peso molecolare:452.5
  • TP1287

    CAS:
    TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.
    Formula:C21H21ClNO8P
    Colore e forma:Solid
    Peso molecolare:481.82
  • 5,10-Dideazafolic acid

    CAS:
    5,10-Dideazafolic acid is an antileukemic drug.
    Formula:C21H21N5O6
    Colore e forma:Solid
    Peso molecolare:439.42
  • 2'-Fluorothymidine

    CAS:
    <p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>
    Formula:C10H13FN2O5
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:260.22
  • 8RK64

    CAS:
    8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .
    Formula:C14H16N8O2S
    Colore e forma:Solid
    Peso molecolare:360.4
  • Chrysotobibenzyl

    CAS:
    Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.
    Formula:C19H24O5
    Colore e forma:Solid
    Peso molecolare:332.39
  • Antibacterial agent 124

    CAS:
    Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.
    Formula:C16H17ClFN3O2
    Colore e forma:Solid
    Peso molecolare:337.78
  • JA2131

    CAS:
    JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.
    Formula:C13H19N5O2S2
    Colore e forma:Solid
    Peso molecolare:341.45
  • Poloxipan

    CAS:
    Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.
    Formula:C14H10BrN3O3S
    Colore e forma:Solid
    Peso molecolare:380.22
  • Integrin modulator 1

    CAS:
    Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.
    Formula:C13H14N2O4
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:262.26
  • CDK7-IN-20


    CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.
    Formula:C30H26N6O3
    Colore e forma:Solid
    Peso molecolare:518.57
  • Zelpolib

    CAS:
    Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.
    Formula:C22H21N3O5S2
    Purezza:98.79%
    Colore e forma:Solid
    Peso molecolare:471.55
  • c-Myc inhibitor 9

    CAS:
    c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.
    Formula:C27H31N5OS
    Colore e forma:Solid
    Peso molecolare:473.63
  • BMS-587101

    CAS:
    BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.
    Formula:C26H20Cl2N4O4S
    Colore e forma:Solid
    Peso molecolare:555.43
  • ML372

    CAS:
    ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.
    Formula:C18H20N2O4S
    Colore e forma:Solid
    Peso molecolare:360.43
  • RSK-IN-1

    CAS:
    RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].
    Formula:C22H17NO2
    Colore e forma:Solid
    Peso molecolare:327.38
  • ERCC1-XPF-IN-1

    CAS:
    ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.
    Formula:C28H32ClN5O2
    Colore e forma:Solid
    Peso molecolare:506.04
  • MtTMPK-IN-6

    CAS:
    MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.
    Formula:C23H25N3O3
    Colore e forma:Solid
    Peso molecolare:391.46
  • DIF-3

    CAS:
    DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.
    Formula:C13H17ClO4
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:272.72
  • Eprociclovir

    CAS:
    Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of
    Formula:C11H15N5O3
    Purezza:98.50% - 99.86%
    Colore e forma:Solid
    Peso molecolare:265.27
  • SEL120-34A

    CAS:
    SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.
    Formula:C15H18Br2N4
    Purezza:99.764% - 99.84%
    Colore e forma:Solid
    Peso molecolare:414.14
  • Cytembena

    CAS:
    Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.
    Formula:C11H8BrNaO4
    Purezza:99.7%
    Colore e forma:White Powder
    Peso molecolare:307.07
  • CD532

    CAS:
    CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.
    Formula:C26H25F3N8O
    Purezza:99.99%
    Colore e forma:Solid
    Peso molecolare:522.52
  • CDK4/6/1 Inhibitor

    CAS:
    CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).
    Formula:C28H30F2N6
    Purezza:97.25% - 99.72%
    Colore e forma:Solid
    Peso molecolare:488.57
  • D-I03

    CAS:
    D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.
    Formula:C23H36N6S
    Purezza:99.65%
    Colore e forma:Solid
    Peso molecolare:428.64
  • 9-Isopropylolomoucine

    CAS:
    9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.
    Formula:C17H22N6O
    Purezza:99.82%
    Colore e forma:Solid
    Peso molecolare:326.4
  • PCSK9-IN-10

    CAS:
    <p>PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.</p>
    Formula:C18H23N5O4
    Purezza:99.06%
    Colore e forma:Soild
    Peso molecolare:373.41
  • DS18561882

    CAS:
    DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.
    Formula:C28H31F3N4O6S
    Purezza:98.19% - >99.99%
    Colore e forma:Solid
    Peso molecolare:608.63
  • 116-9e

    CAS:
    116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.
    Formula:C31H32N2O5
    Purezza:99.55%
    Colore e forma:Solid
    Peso molecolare:512.6
  • Talviraline

    CAS:
    Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a
    Formula:C15H20N2O3S2
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:340.46
  • UMK57

    CAS:
    UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,
    Formula:C17H17N3S
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:295.4
  • Galocitabine

    CAS:
    Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.
    Formula:C19H22FN3O8
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:439.39
  • hDHODH-IN-7

    CAS:
    hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.
    Formula:C21H23FN4O
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:366.43
  • hSMG-1 inhibitor 11e

    CAS:
    hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.
    Formula:C26H27N7O3S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:517.6
  • DENV-IN-5

    CAS:
    Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.
    Formula:C23H25ClF2N4OS
    Purezza:99.42%
    Colore e forma:Solid
    Peso molecolare:478.99
  • ITX3

    CAS:
    ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.
    Formula:C22H17N3OS
    Purezza:97.28%
    Colore e forma:Solid
    Peso molecolare:371.45
  • AzddMeC

    CAS:
    <p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>
    Formula:C10H14N6O3
    Purezza:97.14% - 99.62%
    Colore e forma:Solid
    Peso molecolare:266.26
  • 10-Formylfolic acid

    CAS:
    10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.
    Formula:C20H19N7O7
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:469.41
  • Poloxin-2

    CAS:
    Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.
    Formula:C16H15NO3
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:269.3
  • GRK6-IN-1

    CAS:
    GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.
    Formula:C22H23ClN6O2
    Purezza:99.37%
    Colore e forma:Solid
    Peso molecolare:438.91
  • Haspin-IN-3

    CAS:
    <p>Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.</p>
    Formula:C16H10N2O3
    Purezza:98.78%
    Colore e forma:Solid
    Peso molecolare:278.26