Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(115 prodotti)
- CDK(547 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(46 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(227 prodotti)
- HSP(180 prodotti)
- Integrina(269 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(21 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(127 prodotti)
- PLK(25 prodotti)
- ROCK(61 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3912 prodotti di "Ciclo cellulare/Checkpoint"
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Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purezza:95.29% - >99.99%Colore e forma:SolidPeso molecolare:603.67TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purezza:98.49% - 99.62%Colore e forma:SolidPeso molecolare:588.07MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Formula:C18H17ClN4OPurezza:98.93%Colore e forma:SolidPeso molecolare:340.81Ref: TM-TQ0266
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg462,00€50mg692,00€100mg964,00€MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Formula:C62H109N23O13Purezza:99.57%Colore e forma:SolidPeso molecolare:1384.67R-IMPP
CAS:R-IMPP is an inhibitor of PCSK9 translation.Formula:C24H27N3O2Purezza:99.47% - 99.85%Colore e forma:SolidPeso molecolare:389.49Ref: TM-T4058
1mg46,00€2mg56,00€1mL*10mM (DMSO)75,00€5mg88,00€10mg140,00€25mg280,00€50mg500,00€100mg718,00€CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurezza:99.66%Colore e forma:SolidPeso molecolare:486.38Ref: TM-T8930
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Formula:C12H13FN4O5Colore e forma:SolidPeso molecolare:312.257Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Formula:C20H21N7O7·CaPurezza:99.07% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:511.5Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formula:C10H17N2O14P3·XNaPurezza:99.78%Colore e forma:White Amorphous PowderPeso molecolare:482.17（free base）BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purezza:99.47% - 99.84%Colore e forma:SolidPeso molecolare:360.41Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurezza:97.51% - 99.51%Colore e forma:SolidPeso molecolare:427.32Ref: TM-T1911
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg92,00€25mg166,00€50mg259,00€100mg452,00€500mg982,00€Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Formula:C19H20FN3O3Purezza:99.77% - 99.8%Colore e forma:SolidPeso molecolare:357.38TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formula:C9H2Cl4O2Purezza:99.34%Colore e forma:SolidPeso molecolare:283.92GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Formula:C20H18N4OPurezza:98.64%Colore e forma:SolidPeso molecolare:330.38Ref: TM-T5461
1mg66,00€2mg96,00€5mg144,00€1mL*10mM (DMSO)158,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Formula:C28H28N6O4Purezza:98.66% - 98.8%Colore e forma:SolidPeso molecolare:512.56Ref: TM-T4482
1mg50,00€5mg105,00€1mL*10mM (DMSO)120,00€10mg170,00€25mg340,00€50mg512,00€100mg733,00€500mg1.513,00€TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Formula:C19H18BrIN4O2Purezza:98.38% - 98.73%Colore e forma:SolidPeso molecolare:541.18Simeprevir sodium
CAS:Simeprevir is a drug for the treatment and cure of hepatitis C.Formula:C38H46N5NaO7S2Purezza:98%Colore e forma:SolidPeso molecolare:771.92CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purezza:96.2% - 99.81%Colore e forma:SolidPeso molecolare:456.37ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.593'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Formula:C10H13N5O4Purezza:98.85% - 98.96%Colore e forma:SolidPeso molecolare:267.24
