Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(115 prodotti)
- CDK(547 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(227 prodotti)
- HSP(180 prodotti)
- Integrina(269 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(126 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3909 prodotti di "Ciclo cellulare/Checkpoint"
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dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFormula:C10H16N5O13P3Purezza:99.64%Colore e forma:SolidPeso molecolare:507.182'-Fluoro-2'-Deoxyadenosine
CAS:2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).Formula:C10H12FN5O3Purezza:99.95%Colore e forma:SolidPeso molecolare:269.23Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formula:C28H26Cl2N4O5Purezza:99.26% - 99.72%Colore e forma:SolidPeso molecolare:569.44Levomefolate calcium
CAS:Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.Formula:C20H23CaN7O6Purezza:97.35%Colore e forma:Off-White To Pale Yellow SolidPeso molecolare:497.52AZD-7762
CAS:AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Formula:C17H19FN4O2SPurezza:98.96% - 99.19%Colore e forma:SolidPeso molecolare:362.42Ref: TM-T6093
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg90,00€25mg167,00€50mg265,00€100mg424,00€CCG-100602
CAS:CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formula:C21H17ClF6N2O2Purezza:99.58%Colore e forma:SolidPeso molecolare:478.82Ref: TM-T22062
5mg35,00€1mL*10mM (DMSO)40,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€Abemaciclib
CAS:Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formula:C27H32F2N8Purezza:99.43% - 99.87%Colore e forma:SolidPeso molecolare:506.59NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormula:C38H43N3O6Purezza:99.16% - 99.27%Colore e forma:SolidPeso molecolare:637.76NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Formula:C13H16NNaO4SPurezza:99.64%Colore e forma:SolidPeso molecolare:305.32BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurezza:99.21%Colore e forma:SolidPeso molecolare:416.99Ref: TM-T6162
200mgPrezzo su richiesta1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg250,00€50mg416,00€100mg645,00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formula:C5H7N6NaO5SPurezza:99.55%Colore e forma:SolidPeso molecolare:286.2NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFormula:C13H10Cl4N2O4Purezza:99.78%Colore e forma:SolidPeso molecolare:400.04Ref: TM-T9168
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)80,00€10mg90,00€25mg164,00€50mg227,00€100mg358,00€500mg842,00€Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Purezza:97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%Colore e forma:LiquidPeso molecolare:146.19 kDaJNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurezza:99.1% - 99.85%Colore e forma:SolidPeso molecolare:394.36Ref: TM-T6126
1mg48,00€1mL*10mM (DMSO)94,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€6-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).Formula:C8H7BrO3Purezza:99.82%Colore e forma:SolidPeso molecolare:231.04Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurezza:97.45% - 99.4%Colore e forma:SolidPeso molecolare:559.61Ref: TM-T8487
1mg86,00€5mg173,00€1mL*10mM (DMSO)231,00€10mg261,00€25mg425,00€50mg583,00€100mg803,00€200mg1.063,00€4μ8C
CAS:4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.Formula:C11H8O4Purezza:97.48% - 98.45%Colore e forma:SolidPeso molecolare:204.18Isoindigotin
CAS:Isoindigotin is used in the therapy of Y.
Formula:C16H10N2O2Purezza:98.14% - ≥95%Colore e forma:SolidPeso molecolare:262.26Pyridostatin Trihydrochloride
CAS:Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.Formula:C31H35Cl3N8O5Purezza:99.69%Colore e forma:SolidPeso molecolare:706.026-Thioinosine
CAS:6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.Formula:C10H12N4O4SPurezza:97.74%Colore e forma:SolidPeso molecolare:284.29
