Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(115 prodotti)
- CDK(546 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(227 prodotti)
- HSP(180 prodotti)
- Integrina(268 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(126 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3904 prodotti di "Ciclo cellulare/Checkpoint"
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TMPyP4 tosylate
CAS:TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.Formula:C72H66N8O12S4Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:1363.6Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFormula:C31H32N8O5Purezza:98%Colore e forma:SolidPeso molecolare:596.64Adavosertib
CAS:Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formula:C27H32N8O2Purezza:98.65% - 99.86%Colore e forma:SolidPeso molecolare:500.6Ref: TM-T2077
5mg46,00€10mg66,00€25mg81,00€50mg96,00€100mg110,00€200mg161,00€500mg260,00€1mL*10mM (DMSO)49,00€CK7
CAS:CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formula:C14H12N6O2SPurezza:99.54%Colore e forma:SolidPeso molecolare:328.35Ref: TM-T9615
1mg50,00€5mg114,00€10mg177,00€25mg356,00€50mg557,00€100mg858,00€200mg1.153,00€1mL*10mM (DMSO)126,00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purezza:98.68% - 99.77%Colore e forma:SolidPeso molecolare:385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€1mL*10mM (DMSO)69,00€Risdiplam
CAS:Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formula:C22H23N7OPurezza:98.68% - 99.64%Colore e forma:SolidPeso molecolare:401.46Ro3280
CAS:Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formula:C27H35F2N7O3Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:543.61HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formula:C17H13NO2Purezza:99.96%Colore e forma:SolidPeso molecolare:263.29IMT1B
CAS:IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formula:C24H21ClFNO6Purezza:98.26% - 99.83%Colore e forma:SolidPeso molecolare:473.88Ref: TM-T8842
1mg138,00€5mg295,00€10mg505,00€25mg733,00€50mg888,00€100mg1.251,00€1mL*10mM (DMSO)309,00€AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurezza:>99.99%Colore e forma:SolidPeso molecolare:405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€1mL*10mM (DMSO)286,00€BRD9876
CAS:BRD9876 is a selective inhibitor of MM1S growth.Formula:C16H14N2Purezza:97.81%Colore e forma:SolidPeso molecolare:234.3RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formula:C23H20N6O3Purezza:99.04% - 99.72%Colore e forma:SolidPeso molecolare:428.44T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormula:C29H27NO8Purezza:97.88% - 99.29%Colore e forma:SolidPeso molecolare:517.53Ref: TM-T5416
1mg48,00€5mg96,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€1mL*10mM (DMSO)107,00€Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purezza:97.09% - 99.84%Colore e forma:SolidPeso molecolare:938.71BUR1
CAS:BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formula:C16H17N5Purezza:90%Colore e forma:SolidPeso molecolare:279.34LP-935509
CAS:LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.Formula:C20H24N6O3Purezza:98.34% - 99.64%Colore e forma:SolidPeso molecolare:396.44Ref: TM-T15781
1mg37,00€2mg49,00€5mg79,00€10mg124,00€25mg239,00€50mg444,00€100mg647,00€1mL*10mM (DMSO)87,00€H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purezza:>99.99%Colore e forma:SolidPeso molecolare:614.61Alovudine
CAS:3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.Formula:C10H13FN2O4Purezza:99.41%Colore e forma:Less Solid Colourless SolidPeso molecolare:244.22Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurezza:99.54% - 99.62%Colore e forma:SolidPeso molecolare:493.57Peldesine dihydrochloride
CAS:Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.Formula:C12H13Cl2N5OColore e forma:SolidPeso molecolare:314.17
