Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(115 prodotti)
- CDK(546 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(227 prodotti)
- HSP(180 prodotti)
- Integrina(269 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(274 prodotti)
- PKC(126 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3905 prodotti di "Ciclo cellulare/Checkpoint"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Hu7691
CAS:Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Formula:C22H22ClF3N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:450.887BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purezza:99.67%Colore e forma:SolidPeso molecolare:356.17SBC-115337
CAS:SBC-115337 is a PCSK9 inhibitor.Formula:C29H19N3O4Purezza:99.41%Colore e forma:SolidPeso molecolare:473.48Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Formula:C38H47N5O7S2Purezza:99.45% - 99.92%Colore e forma:SolidPeso molecolare:749.94WR99210 hydrochloride(47326-86-3 free base)
CAS:WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Formula:C14H19Cl4N5O2Purezza:97.77% - 99.8%Colore e forma:SolidPeso molecolare:431.14Ref: TM-T17257L
1mg62,00€5mg132,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€1mL*10mM (DMSO)157,00€WNK-IN-11
CAS:WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Formula:C21H21Cl2N5OSPurezza:98.32%Colore e forma:SolidPeso molecolare:462.4Ref: TM-T5456
1mg87,00€5mg172,00€10mg280,00€25mg474,00€50mg683,00€100mg964,00€500mg1.918,00€1mL*10mM (DMSO)188,00€3'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Formula:C10H13N5O4Purezza:98.85% - 98.96%Colore e forma:SolidPeso molecolare:267.24Phosphonoformic acid trisodium salt hexa
CAS:Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.Formula:CH12Na3O11PPurezza:98%Colore e forma:SolidPeso molecolare:300.03Cyclo(RGDyK) trifluoroacetate
CAS:Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formula:C31H43F6N9O12Purezza:95.28% - ≥95%Colore e forma:SolidPeso molecolare:847.72PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formula:C14H11F3N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:296.24Ref: TM-T12438
1mg52,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)92,00€GAK inhibitor 49 hydrochloride
Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.Formula:C20H23ClN2O5Colore e forma:SolidPeso molecolare:406.86Tirapazamine
CAS:Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Formula:C7H6N4O2Purezza:96.65% - 99.87%Colore e forma:Orange-Red Crystalline PowderPeso molecolare:178.15LDN-192960 hydrochloride
CAS:LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.Formula:C18H22Cl2N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:401.35Levofloxacin hydrochloride
CAS:Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H21ClFN3O4Purezza:99.78% - 99.98%Colore e forma:SolidPeso molecolare:397.8Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formula:C41H44N4O10SPurezza:98.11%Colore e forma:SolidPeso molecolare:784.87M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formula:C20H16ClN5O2Purezza:98.01%Colore e forma:SolidPeso molecolare:393.83Ref: TM-T11929
1mg84,00€5mg152,00€10mg236,00€25mg447,00€50mg670,00€100mg982,00€1mL*10mM (DMSO)167,00€CRT0066854
CAS:CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.Formula:C24H25N5SColore e forma:SolidPeso molecolare:415.55Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formula:C26H32ClN7O4SColore e forma:SolidPeso molecolare:574.09Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Formula:C9H11ClN4O2Purezza:99.815%Colore e forma:SolidPeso molecolare:242.66Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purezza:98.33% - 99.58%Colore e forma:SolidPeso molecolare:355.36
